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  3. 4'-Nitroacetophenone

4'-Nitroacetophenone is a nitro-aromatic compound that is an intermediate of the pharmaceutical chloramphenicol and a dye intermediate that can be used in the manufacture of synthomycin and chloramphenicol.

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4'-Nitroacetophenone Chemical Structure

4'-Nitroacetophenone Chemical Structure

CAS No. : 100-19-6

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Based on 1 publication(s) in Google Scholar

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Description

4'-Nitroacetophenone is a nitro-aromatic compound that is an intermediate of the pharmaceutical chloramphenicol and a dye intermediate that can be used in the manufacture of synthomycin and chloramphenicol[1].

Molecular Weight

165.15

Formula

C8H7NO3

CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

CC(C1=CC=C([N+]([O-])=O)C=C1)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 200 mg/mL (1211.02 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 6.0551 mL 30.2755 mL 60.5510 mL
5 mM 1.2110 mL 6.0551 mL 12.1102 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.48%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 6.0551 mL 30.2755 mL 60.5510 mL 151.3775 mL
5 mM 1.2110 mL 6.0551 mL 12.1102 mL 30.2755 mL
10 mM 0.6055 mL 3.0276 mL 6.0551 mL 15.1378 mL
15 mM 0.4037 mL 2.0184 mL 4.0367 mL 10.0918 mL
20 mM 0.3028 mL 1.5138 mL 3.0276 mL 7.5689 mL
25 mM 0.2422 mL 1.2110 mL 2.4220 mL 6.0551 mL
30 mM 0.2018 mL 1.0092 mL 2.0184 mL 5.0459 mL
40 mM 0.1514 mL 0.7569 mL 1.5138 mL 3.7844 mL
50 mM 0.1211 mL 0.6055 mL 1.2110 mL 3.0276 mL
60 mM 0.1009 mL 0.5046 mL 1.0092 mL 2.5230 mL
80 mM 0.0757 mL 0.3784 mL 0.7569 mL 1.8922 mL
100 mM 0.0606 mL 0.3028 mL 0.6055 mL 1.5138 mL
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4'-Nitroacetophenone Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
4'-Nitroacetophenone
Cat. No.:
HY-Y0185
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