2. Signaling Pathways
  3. Vitamin D Related/Nuclear Receptor
  4. Estrogen Receptor/ERR
  5. Estrogen Receptor/ERR Agonist

Estrogen Receptor/ERR Agonist

Estrogen Receptor/ERR Isoform Comparison

Estrogen Receptor/ERR Agonists (94):

Cat. No. Product Name Effect Purity
  • HY-N0233R
    Bavachin (Standard)
    		Agonist
    Bavachin (Standard) is the analytical standard of Bavachin. This product is intended for research and analytical applications. Bavachin, a flavonoid first isolated from seeds of P. corylifolia, acts as a phytoestrogen that activates the estrogen receptors ERα and ERβ with EC50s of 320 and 680 nM, respectively.
  • HY-160856
    TOP5300
    		Agonist
    TOP5300 is an orally active follicle-stimulating hormone receptor allosteric agonist. TOP5300 can induce the production of testosterone in stromal cells and promote follicular genesis and superovulation in rats.
  • HY-N0835R
    (20S)-Protopanaxatriol (Standard)
    		Agonist
    (20S)-Protopanaxatriol (Standard) is the analytical standard of (20S)-Protopanaxatriol. This product is intended for research and analytical applications. (20S)-Protopanaxatriol is a metabolite of ginsenoside. (20S)-Protopanaxatriol works through the glucocorticoid receptor (GR) and estrogen receptor (ER), and is also a LXRα inhibitor. (20S)-Protopanaxatriol shows a broad spectrum of antitumor effects.
  • HY-149584
    CIDD-0149897
    		Agonist 99.91%
    CIDD-0149897 is a potent, selective and brain-penetrant ERβ agonist. CIDD-0149897 exert antitumor functions in glioblastoma.
  • HY-B0487R
    Ethisterone (Standard)
    		Agonist
    Ethisterone (Standard) is the analytical standard of Ethisterone. This product is intended for research and analytical applications. Ethisterone (Pregneninolone), a synthetic steroidal estrogen, is an orally active steroidal contraceptive agent. Ethisterone is reported for androgenic activity, used for the research of the gynecological disorders.
  • HY-160857
    TOP5668
    		Agonist
    TOP5668 is an orally active follicle-stimulating hormone receptor allosteric agonist. TOP5668 can induce the production of testosterone in stromal cells and promote follicular genesis and superovulation in rats.
  • HY-B0141S4
    Estradiol-13C6
    		Agonist
    Estradiol-13C6 is the 13C-labeled Estradiol. Estradiol is a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females. Estradiol upregulates IL-6 expression through the estrogen receptor β (ERβ) pathway[1][2][3].
  • HY-18295A
    rel-Erteberel
    		Agonist
    rel-Erteberel is rel isomer of Erteberel (HY-18295). Erteberel is a potent and selective estrogen receptor beta (ERβ) agonist with Ki and EC50 of 1.54 nM and 3.61 nM, respectively. Erteberel has anti-tumor activities.
  • HY-B0652R
    Etonogestrel (Standard)
    		Agonist
    Etonogestrel (Standard) is the analytical standard of Etonogestrel. This product is intended for research and analytical applications. Etonogestrel (3-Oxodesogestrel), a biologically active metabolite of progestin Desogestrel, binds with high affinity to progesterone receptors and estrogen receptors in the target organs. Etonogestrel induce FKBP51 mRNA and protein expression in cultured human endometrial stromal cells (HESCs).
  • HY-B1361R
    Estropipate (Standard)
    		Agonist
    Estropipate (Standard) is the analytical standard of Estropipate. This product is intended for research and analytical applications.
  • HY-137818
    SR19881
    		Agonist
    SR19881 is a potent dual agonist of ERRγ and ERRβ, with EC50 values of 0.39 and 0.63 μM, respectively.
  • HY-100327
    MK-6913
    		Agonist
    MK-6913 (Tetrahydrofluoroene 52) is a potent and selective estrogen receptor β agonist.
  • HY-123047R
    Tibolone (Standard)
    		Agonist
    Tibolone (Standard) is the analytical standard of Tibolone. This product is intended for research and analytical applications. Tibolone is a broad spectrum gonadal steroid agonist with progestagenic, androgenic, and estrogenic activities. Tibolone can be used for postmenopausal osteoporosis research.
  • HY-149833
    ERRγ inverse agonist 2
    		Agonist
    ERRγ inverse agonist 2 (compound 19) is a potent and selective ERRγ inverse agonist with a Kd value of 6.5 μM. ERRγ inverse agonist 2 inhibits the expression of hepcidin, fibrinogen and gluconeogenic genes. ERRγ inverse agonist 2 has antimicrobial, anti-coagulant and antidiabetic activities.
  • HY-B0141S5
    Estradiol-13C2
    		Agonist
    Estradiol-13C2 is the 13C-labeled Estradiol. Estradiol is a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females. Estradiol upregulates IL-6 expression through the estrogen receptor β (ERβ) pathway[1][2][3].
  • HY-B0234S3
    Estrone-13C2
    		Agonist
    Estrone-13C2 is the 13C-labeled Estrone. Estrone (E1) is a natural estrogenic hormone. Estrone is the main representative of the endogenous estrogens and is produced by several tissues, especially adipose tissue. Estrone is the result of the process of aromatization of androstenedione that occurs in fat cells[1][2].
  • HY-N2682B
    Dehydrodiconiferyl alcohol
    		Agonist
    Dehydrodiconiferyl alcohol is an estrogen receptor agonist that can promote BMP-2-induced osteoblastogenesis. Dehydrodiconiferyl alcohol also exerts anti-inflammatory activity through inactivation of NF-κB pathways.
  • HY-N7748A
    Epi-cryptoacetalide
    		Agonist
    Epi-cryptoacetalide is a natural diterpenoid. Epi-cryptoacetalide reveals high affinity to ER-α and PGE2 receptor (EP2 subtype) with Ki values of 0.3 μM and 1.92 μM, respectively. Epi-cryptoacetalide has anti-endometriosis activities.
  • HY-149500
    CITFA
    		Agonist
    CITFA is a GPER agonist. CITFA can promote neurite growth of hippocampal neurons in rat embryo (E18).
  • HY-B1403R
    Dienestrol (Standard)
    		Agonist
    Dienestrol (Standard) is the analytical standard of Dienestrol. This product is intended for research and analytical applications.