2. Anti-infection
  3. Parasite
  4. Cabraleahydroxylactone

Cabraleahydroxylactone is a dammarane triterpenoid with antimycobacterial activity against Mycobacterium tuberculosis.

For research use only. We do not sell to patients.

Cabraleahydroxylactone Chemical Structure

Cabraleahydroxylactone Chemical Structure

CAS No. : 35833-69-3

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Cabraleahydroxylactone Related Antibodies

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Amebae Coccidia Leishmania Mite Plasmodium Toxoplasma Trypanosoma Schistosome

  • Biological Activity

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Description

Cabraleahydroxylactone is a dammarane triterpenoid with antimycobacterial activity against Mycobacterium tuberculosis[1].

Cellular Effect
Cell Line Type Value Description References
A549 IC50
> 50 μM
Compound: 17
Cytotoxicity against human A549 cells assessed as cell viability after 48 hrs by MTT assay
Cytotoxicity against human A549 cells assessed as cell viability after 48 hrs by MTT assay
[PMID: 24547740]
COLO 205 IC50
> 100 μM
Compound: 15
Cytotoxicity against human COLON205 cells after 48 hrs by MTT assay
Cytotoxicity against human COLON205 cells after 48 hrs by MTT assay
[PMID: 17346076]
HepG2 IC50
> 50 μM
Compound: 17
Cytotoxicity against human HepG2 cells assessed as cell viability after 48 hrs by MTT assay
Cytotoxicity against human HepG2 cells assessed as cell viability after 48 hrs by MTT assay
[PMID: 24547740]
K562 IC50
> 100 μM
Compound: 15
Cytotoxicity against human K562 cells after 48 hrs by MTT assay
Cytotoxicity against human K562 cells after 48 hrs by MTT assay
[PMID: 17346076]
K562/Adr IC50
> 100 μM
Compound: 15
Cytotoxicity against human doxorubicin-resistant K562/Adr cells after 48 hrs by MTT assay
Cytotoxicity against human doxorubicin-resistant K562/Adr cells after 48 hrs by MTT assay
[PMID: 17346076]
K562/Adr IC50
> 100 μM
Compound: 15
Cytotoxicity against human doxorubicin-resistant K562/Adr cells in presence of 1 uM doxorubicin after 48 hrs by MTT assay
Cytotoxicity against human doxorubicin-resistant K562/Adr cells in presence of 1 uM doxorubicin after 48 hrs by MTT assay
[PMID: 17346076]
KB IC50
> 100 μM
Compound: 15
Cytotoxicity against human KB cells after 48 hrs by MTT assay
Cytotoxicity against human KB cells after 48 hrs by MTT assay
[PMID: 17346076]
MCF7 IC50
> 100 μM
Compound: 15
Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
[PMID: 17346076]
MCF7 IC50
> 50 μM
Compound: 17
Cytotoxicity against human MCF7 cells assessed as cell viability after 48 hrs by MTT assay
Cytotoxicity against human MCF7 cells assessed as cell viability after 48 hrs by MTT assay
[PMID: 24547740]
RAW264.7 IC50
> 100 μM
Compound: 17
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-stimulated nitric oxide production after 24 hrs by Griess assay
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-stimulated nitric oxide production after 24 hrs by Griess assay
[PMID: 24547740]
Molecular Weight

416.64

Formula

C27H44O3
CAS No.
SMILES

C[C@]12[C@@](CC[C@@]3([H])[C@]2(CC[C@]3([H])[C@]4(OC(CC4)=O)C)C)([H])[C@@]5([C@@](C(C)([C@@H](CC5)O)C)([H])CC1)C
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Cabraleahydroxylactone Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cabraleahydroxylactone35833-69-3ParasiteInhibitorinhibitorinhibit

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