2. Cell Cycle/DNA Damage
  3. CDK
  4. CDK2-IN-13

CDK2-IN-13 (Compound 15) is a CDK2 inhibitor with an IC50 of 12 µM. CDK2-IN-13 can be used in research of cancer.

For research use only. We do not sell to patients.

CDK2-IN-13 Chemical Structure

CDK2-IN-13 Chemical Structure

CAS No. : 101622-53-1

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Based on 1 publication(s) in Google Scholar

CDK2-IN-13 Related Antibodies

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Description

CDK2-IN-13 (Compound 15) is a CDK2 inhibitor with an IC50 of 12 µM. CDK2-IN-13 can be used in research of cancer[1].

IC50 & Target

IC50:12 µM (CDK2)[1].
Molecular Weight

273.72

Formula

C13H12ClN5
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CN1C=NC2=C(N=C(N=C21)Cl)NCC3=CC=CC=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 11.11 mg/mL (40.59 mM; ultrasonic and warming and adjust pH to 11 with NaOH and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.6534 mL 18.2668 mL 36.5337 mL
5 mM 0.7307 mL 3.6534 mL 7.3067 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.6534 mL 18.2668 mL 36.5337 mL 91.3342 mL
5 mM 0.7307 mL 3.6534 mL 7.3067 mL 18.2668 mL
10 mM 0.3653 mL 1.8267 mL 3.6534 mL 9.1334 mL
15 mM 0.2436 mL 1.2178 mL 2.4356 mL 6.0889 mL
20 mM 0.1827 mL 0.9133 mL 1.8267 mL 4.5667 mL
25 mM 0.1461 mL 0.7307 mL 1.4613 mL 3.6534 mL
30 mM 0.1218 mL 0.6089 mL 1.2178 mL 3.0445 mL
40 mM 0.0913 mL 0.4567 mL 0.9133 mL 2.2834 mL
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CDK2-IN-13 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CDK2-IN-13101622-53-1CDKCyclin dependent kinasecancertumorInhibitorinhibitorinhibit

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