2. Gene
  3. CD300C - CD300c molecule Gene

CD300C - CD300c molecule Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as LIR; CLM-6; CMRF35; IGSF16; CMRF-35; CMRF35A; CMRF-35A; CMRF35A1; CMRF35-A1

Gene ID: 10871 | Gene type: protein coding

About CD300C

Cytogenetic location: 17q25.1 Genomic coordinates (GRCh38): 17:74,534,635-74,546,115 (from NCBI)

This gene has 1 transcript (splice variant), 157 orthologues and 13 paralogues. Broad expression in lung (RPKM 2.9), appendix (RPKM 2.6) and 19 other tissues.

Summary

The CMRF35 antigen, which was identified by reactivity with a monoclonal antibody, is present on monocytes, neutrophils, and some T and B lymphocytes (Jackson et al., 1992 [PubMed 1349532]).[supplied by OMIM, Mar 2008]

CD300C Products(1)

mRNA Protein Name
NM_006678.5 NP_006669.1 CMRF35-like molecule 6 precursor
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
20959446 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CD300C Protein Structure

V-set

V-set: Immunoglobulin V-set domain (27 - 119)

  • 0
  • 100
  • 200
  • 224 a.a.
Protein Preferred Names Protein Names

CMRF35-like molecule 6

CD300 antigen-like family member C

CD300C Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
CD300C Q08708 GPR151 Homo sapiens Q8TDV0
Y2H Prey Pooling
32296183
Intra
CD300C Q08708 GPR151 Homo sapiens Q8TDV0
Validated Y2H
32296183
Intra
CD300C Q08708 GPR151 Homo sapiens Q8TDV0
Y2H Array
32296183
Intra
CD300C Q08708 UNC93A Homo sapiens Q86WB7-2
Validated Y2H
32296183
Intra
CD300C Q08708 UNC93A Homo sapiens Q86WB7-2
Y2H Array
32296183
Intra
CD300C Q08708 UNC93A Homo sapiens Q86WB7-2
Y2H Prey Pooling
32296183
Intra
CD300C Q08708 TMEM167B Homo sapiens Q9NRX6
Y2H Prey Pooling
32296183
Intra
CD300C Q08708 TMEM167B Homo sapiens Q9NRX6
Validated Y2H
32296183
Intra
CD300C Q08708 TMEM167B Homo sapiens Q9NRX6
Y2H Array
32296183
Intra
CD300C Q08708 GPR42 Homo sapiens O15529
Y2H Prey Pooling
32296183
Intra
CD300C Q08708 GPR42 Homo sapiens O15529
Y2H Array
32296183
Intra
CD300C Q08708 FAM210B Homo sapiens Q96KR6
Validated Y2H
32296183
Intra
CD300C Q08708 FAM210B Homo sapiens Q96KR6
Y2H Array
32296183
Intra
CD300C Q08708 FAM210B Homo sapiens Q96KR6
Y2H Prey Pooling
32296183
Intra
CD300C Q08708 CD300LB Homo sapiens A8K4G0
Anti Tag CoIP
20959446
Intra
CD300C Q08708 LEPROTL1 Homo sapiens O95214
Y2H Array
32296183
Intra
CD300C Q08708 LEPROTL1 Homo sapiens O95214
Y2H Prey Pooling
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant CD300C Proteins

Cat. No. Product Name Accession Purity
HY-P76222 CD300c Protein, Human (HEK293, His) Q08708/NP_006669.1 (M29-R183) ≥95%

Related Diseases

Diseases Alias
Gastroduodenal Crohn'S Disease

Upper Gi Crohn'S Disease
Paget'S Disease Of Bone

Osteitis Deformans

Paget Disease Of Bone

Osseous Paget'S Disease

Paget Disease Of Bone, Familial

Bone Paget Disease

Familial Paget'S Disease Of Bone

Paget'S Bone Disease

Familial Paget Disease Of Bone

Paget Disease, Bone

Pdb

Pagets Bone Disease
Frontotemporal Dementia And/Or Amyotrophic Lateral Sclerosis 1

FTDALS1

Frontotemporal Dementia And/Or Motor Neuron Disease

Ftdmnd

Amyotrophic Lateral Sclerosis And/Or Frontotemporal Dementia

Alsftd

Frontotemporal Dementia And/Or Amyotrophic Lateral Sclerosis

Frontotemporal Dementia And/Or Amyotrophic Lateral Sclerosis-1

Frontotemporal Dementia With Motor Neuron Disease

Ftdals

Ftd-Als

Ftd-Mnd

Frontotemporal Dementia With Amyotrophic Lateral Sclerosis

Amyotrophic Lateral Sclerosis With Frontotemporal Dementia 1

Amyotrophic Lateral Sclerosis/Frontotemporal Dementia

Dementia, Frontotemporal, And/Or Amyotrophic Lateral Sclerosis

Amyotrophic Lateral Sclerosis And/Or Frontotemporal Dementia 1

Frontotemporal Lobar Degeneration

Grn-Related Frontotemporal Dementia
Zellweger Syndrome

Cerebrohepatorenal Syndrome

Zellweger Leukodystrophy

Zs

Congenital Iron Overload

Chr

Zws

Severe Pbd-Zsd

Severe Peroxisome Biogenesis Disorder-Zellweger Spectrum Disorder
Amyotrophic Lateral Sclerosis 1

Amyotrophic Lateral Sclerosis

ALS

Lou Gehrig Disease

Amyotrophic Lateral Sclerosis Type 1

Charcot Disease

ALS1

Amyotrophic Lateral Sclerosis, Susceptibility To

Fals

Lou Gehrig'S Disease

Mnd

Motor Neuron Disease

Familial Amyotrophic Lateral Sclerosis

Amyotrophic Lateral Sclerosis 1, Familial

Amyotrophic Lateral Sclerosis 1, Autosomal Dominant

Motor Neuron Disease, Bulbar

Motor Neurone Disease

Amyotrophic Lateral Sclerosis With Dementia

Dementia With Amyotrophic Lateral Sclerosis

Motor Neuron Disease, Amyotrophic Lateral Sclerosis

Sclerosis, Lateral, Amyotrophic

Sclerosis, Lateral, Amyotrophic, Type 1

Amyotrophic Sclerosis

Als - [Amyotrophic Lateral Sclerosis]

Wasting Palsy

Amyotrophic Paralysis

Amyotrophy Lateral Sclerosis

Wasting Paralysis

Spinal Progressive Amyotrophy

Progressive Atrophic Paralysis
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS02227 CD300C Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta CD300C VGNC VGNC:99134
Rattus norvegicus CD300C RGD RGD:1565161
Others CD300C NCBI