2. Gene
  3. Sri - sorcin Gene

Sri - sorcin Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Sor; 2210417O06Rik; 2900070H08Rik

Gene ID: 109552 | Gene type: protein coding

About Sri

Summary

Enables DNA-binding transcription factor binding activity. Involved in several processes, including cytoplasmic sequestering of transcription factor; negative regulation of cardiac muscle contraction; and positive regulation of transport. Acts upstream of or within calcium ion transport. Located in Z disc; plasma membrane; and vesicle. Orthologous to human SRI (sorcin). [provided by Alliance of Genome Resources, Apr 2022]

Sri Products(2)

mRNA Protein Name
NM_001080974.2 NP_001074443.1 sorcin isoform 1
NM_025618.3 NP_079894.2 sorcin isoform 2
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables DNA-binding transcription factor binding IPI
IPI: Inferred from physical interaction
22338092 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
14644162 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within calcium ion transport IPI
IPI: Inferred from physical interaction
16204356 MGI
involved in cytoplasmic sequestering of transcription factor IMP
IMP: Inferred from mutant phenotype
22338092 MGI
involved in negative regulation of cardiac muscle contraction IMP
IMP: Inferred from mutant phenotype
22326846 MGI
involved in negative regulation of transcription regulatory region DNA binding IMP
IMP: Inferred from mutant phenotype
22338092 MGI
involved in positive regulation of insulin secretion involved in cellular response to glucose stimulus IMP
IMP: Inferred from mutant phenotype
22338092 MGI
involved in positive regulation of release of sequestered calcium ion into cytosol IMP
IMP: Inferred from mutant phenotype
22338092 MGI
Cellular Component GO Annotation Evidence Reference Source
located in Z disc IDA
IDA: Inferred from direct assay
12754254 MGI
located in intracellular anatomical structure IDA
IDA: Inferred from direct assay
14644162 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
14644162 MGI
located in vesicle IDA
IDA: Inferred from direct assay
12925238 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

sorcin

Related Agents

Pre-clinical Phase
Bioactive Molecules (19)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-100347A SRI-011381 hydrochloride Agonist 98.20% Unkown
HY-100347 SRI-011381 Agonist 99.58% Unkown
HY-19956 GI254023X Inhibitor 99.67% Unkown
HY-142114 SRI-37330 Inhibitor 99.16% Unkown
HY-141623 SRI-37330 hydrochloride Inhibitor 99.72% Unkown
HY-150090 SRI-41315 Activator 99.68% Unkown
HY-148853 SRI-42127 Inhibitor 99.80% Unkown
HY-114363A SRI 31215 TFA Inhibitor 98.53% Unkown
HY-123600 SRI-29329 Inhibitor 99.73% Unkown
HY-150089 SRI-37240 Modulator 99.21% Unkown
HY-117002 SRI 37892 Inhibitor 98.92% Unkown
HY-117902 SRI-31142 / Unkown
HY-112580 SRI-31040 / Unkown
HY-126158 SRI-29574 / Unkown
HY-147251 SRI 6409-94 98.60% Unkown
HY-160783 SRI-43265 Inhibitor 99.08% Unkown
HY-RS13767 SRI Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-100347S SRI-011381-d5 Agonist / Unkown
HY-N9533 16R-Hydroxy-3-oxolanosta7,9(11),24-trien-21-oic acid / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sri NCBI NCBI:6717
Macaca fascicularis Sri NCBI NCBI:102138728
Macaca mulatta Sri NCBI NCBI:705215