2. Gene
  3. VASN - vasorin Gene

VASN - vasorin Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as SLITL2

Gene ID: 114990 | Gene type: protein coding

About VASN

Cytogenetic location: 16p13.3 Genomic coordinates (GRCh38): 16:4,371,848-4,383,538 (from NCBI)

This gene has 1 transcript (splice variant), 1 gene allele, 255 orthologues and 22 paralogues. Broad expression in placenta (RPKM 16.9), kidney (RPKM 16.4) and 24 other tissues.

Summary

Enables transforming growth factor beta binding activity. Involved in negative regulation of epithelial to mesenchymal transition and negative regulation of transforming growth factor beta receptor signaling pathway. Located in cell surface and extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]

VASN Products(1)

mRNA Protein Name
NM_138440.3 NP_612449.2 vasorin precursor

VASN Protein Structure

LRRNT

LRRNT: Leucine rich repeat N-terminal domain (23 - 51)

LRR_1

LRR_1: Leucine Rich Repeat (78 - 98)

LRR_8

LRR_8: Leucine rich repeat (101 - 160)

LRR_8

LRR_8: Leucine rich repeat (193 - 249)

  • 0
  • 200
  • 400
  • 600
  • 673 a.a.
Protein Preferred Names Protein Names

vasorin

protein slit-like 2

Recombinant VASN Proteins

Cat. No. Product Name Accession Purity
HY-P70999 Vasorin Protein, Human (552a.a, HEK293, His) Q6EMK4/AAH68575.1 (C24-P575) ≥95%

Related Diseases

Diseases Alias
Hematuria, Benign Familial

Benign Familial Hematuria

BFH

Thin Membrane Nephropathy

Tmn

Thin Basement Membrane Nephropathy

Thin-Basement-Membrane Nephropathy

Hematuria, Familial Benign

Hematuria Benign Familial

Hematuria, Benign, Familial

Thin Basement Membrane Disease
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15608 VASN Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus VASN MGD MGI:2177651
Canis familiaris VASN VGNC VGNC:54089
Rattus norvegicus VASN RGD RGD:1598149
Felis catus VASN VGNC VGNC:66921
Others VASN NCBI