1. Gene
  2. CCR5 - C-C motif chemokine receptor 5 Gene

CCR5 - C-C motif chemokine receptor 5 Gene

Homo sapiens

Also known as CKR5; CCR-5; CD195; CKR-5; CCCKR5; CMKBR5; IDDM22; CC-CKR-5

Gene ID: 1234 | Gene type: protein coding

About CCR5

Cytogenetic location: 3p21.31 Genomic coordinates (GRCh38): 3:46,370,142-46,376,206 (from NCBI)

This gene has 2 transcripts (splice variants), 151 orthologues, 23 paralogues and is associated with 3 phenotypes. Broad expression in appendix (RPKM 9.4), lymph node (RPKM 7.4) and 21 other tissues.

Summary

This gene encodes a member of the beta Chemokine Receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV Infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the Chemokine Receptor gene cluster region. An allelic polymorphism in this gene results in both functional and non-functional alleles; the reference genome represents the functional allele. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2015]

CCR5 Products(3)

mRNA Protein Name
NM_001100168.2 NP_001093638.1 C-C chemokine receptor type 5
NM_000579.4 NP_000570.1 C-C chemokine receptor type 5
NM_001394783.1 NP_001381712.1 C-C chemokine receptor type 5
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables C-C chemokine binding IPI
IPI: Inferred from physical interaction
8699119 GOA
enables C-C chemokine receptor activity IDA
IDA: Inferred from direct assay
8639485 GOA
enables actin binding IDA
IDA: Inferred from direct assay
12421915 GOA
enables chemokine (C-C motif) ligand 5 binding IPI
IPI: Inferred from physical interaction
8699119 GOA
enables identical protein binding IPI
IPI: Inferred from physical interaction
18230715 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
10816381 GOA
Biological Process GO Annotation Evidence Reference Source
involved in G protein-coupled receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
19523456 GOA
involved in MAPK cascade IEP
IEP: Inferred from expression pattern
12032188 GOA
involved in calcium ion transport IDA
IDA: Inferred from direct assay
8699119 GOA
involved in calcium-mediated signaling IDA
IDA: Inferred from direct assay
10679098 GOA
involved in cell-cell signaling IDA
IDA: Inferred from direct assay
10679098 GOA
involved in cellular response to lipopolysaccharide IEP
IEP: Inferred from expression pattern
10679098 GOA
involved in release of sequestered calcium ion into cytosol by sarcoplasmic reticulum IDA
IDA: Inferred from direct assay
19523456 GOA
involved in response to cholesterol IMP
IMP: Inferred from mutant phenotype
19523456 GOA
involved in signaling IEP
IEP: Inferred from expression pattern
12032188 GOA
Cellular Component GO Annotation Evidence Reference Source
is active in cell surface IDA
IDA: Inferred from direct assay
29739880 GOA
located in cell surface IDA
IDA: Inferred from direct assay
10521508 GOA
located in endosome IDA
IDA: Inferred from direct assay
10679098 GOA
located in external side of plasma membrane IDA
IDA: Inferred from direct assay
10383387 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CCR5 Protein Structure

7tm_1

7tm_1: 7 transmembrane receptor (rhodopsin family) (47 - 297)

  • 0
  • 100
  • 200
  • 300
  • 352 a.a.
Protein Preferred Names Protein Names

C-C chemokine receptor type 5

C-C motif chemokine receptor 5 A159A

HIV-1 fusion coreceptor

chemokine (C-C motif) receptor 5

chemokine receptor CCR5

chemokine recptor CCR5 Delta32

chemr13

mutant C-C motif chemokine receptor

Related Diseases

Diseases Alias
Leukemia, Chronic Lymphocytic

Chronic Lymphocytic Leukemia

B-Cell Chronic Lymphocytic Leukemia

CLL

B-Cell Chronic Lymphoid Leukemia

Chronic Lymphatic Leukemia

Chronic Lymphocytic Leukaemia

Lymphoplasmacytic Leukemia

Small Lymphocytic Lymphoma

Leukemia, Chronic Lymphatic

B-Cell Chronic Lymphocytic Leukaemia

Chronic Lymphatic Leukaemia

Lymphoplasmacytic Leukaemia

B Cell Chronic Lymphocytic Leukemia

Chronic B-Cell Lymphocytic Leukemia

Leukemia, Lymphocytic, Chronic

B-Cll

Chronic Lymphoid Leukemia

Leukemia Lymphocytic Chronic

Lymphoma Small Lymphocytic

Leukemia, Lymphocytic, Chronic, B-Cell

Glomerulonephritis

Bright'S Disease

Encephalitis

Mumps Encephalitis

Mumps Meningoencephalitis

Herpes Simplex Neuroinvasion

Herpetic Encephalitis

Herpetic Encephalopathy

Herpes Simplex Encephalitis, Myelitis Or Encephalomyelitis

Encephalitis Due To Herpesviridae

Encephalitis Due To Herpesvirus

Herpes Encephalitis

Herpesviral Encephalitis

Herpes Simplex Encephalitis

Hsv - [Herpes Simplex Virus] Encephalitis

Herpes Virus Encephalitis

Simian B Disease

Simian B Disorder

Encephalitis Nec

Idiopathic Encephalitis

Human Immunodeficiency Virus Infectious Disease

Hiv Infections

Myocarditis

Myocardial Inflammation

Inflammatory Cardiomyopathy

Rheumatoid Arthritis

RA

Arthritis, Rheumatoid

Rheumatoid Arthritis, Susceptibility To

Arthritis Or Polyarthritis, Rheumatic

Atrophic Arthritis

Rheumatism Arthritis

Rheumatoid Polyarthritis

Pneumoconiosis

Pneumoconioses

Silicosis Nos

Complicated Silicosis

Fibrosis Of Lung With Silicosis

Nodular Silicosis

Pneumoconiosis Due To Silica

Silicotic Fibrosis Of Lung

Simple Silicosis

Silicatosis

Silicotic Lung Fibrosis

Pneumoconiosis Due To Talc

Pulmonary Talcosis

Talc Lung Disease

Talc Pneumoconiosis

Talc Workers' Pneumoconiosis

Talcosis

Fibrosis Of Lung Due To Talc

Asbestos Pneumoconiosis

Amianthosis

Asbestosis

Lung Fibrosis With Asbestosis

Pulmonary Asbestosis

Central Nervous System Disease

CNS

Cns Diseases

Central Nervous System Diseases

Cns Disorder

Bubonic Plague

Black Death

Plague, Bubonic

Plague, Septicemic

Pestis Bubonica

Primary Bacterial Infectious Disease
Lymphoma

Lymphoid Cancer

Lymphomas

Lymphoid Cancers

Lymphoid Neoplasm

Lymphoma Nos

Nhl - [Non-Hodgkin Lymphoma]

Non-Hodgkin Lymphoma

Non-Hodgkin Lymphoma, Nos

Non-Hodgkin Malignant Lymphoma Nos

Bacterial Vaginosis

Vaginosis, Bacterial

Yellow Fever

Urban Yellow Fever

Jungle Yellow Fever

Sylvatic Yellow Fever

Yf

Yellow Fever, Sylvan

Bronze John

Yellow Jack

Yf- [Yellow Fever]

Febris Flava

Leishmaniasis

Post-Kala-Azar Dermal Leishmaniasis

Post Kala-Azar Dermal Leishmaniasis

Post-Kala-Azar Dermal Infectious Disease By Leishmaniasis

Cutaneous Leishmaniasis

Kala-Azar

Visceral Leishmaniasis

Leishmaniasis, Cutaneous

Leishmaniasis, Visceral

Leishmania

Leishmania Infection

Leishmaniosis

Parasitic Protozoa Infectious Disease

Protozoan Infections

Mastigophora Infectious Disease

Sarcomastigophora Infectious Disease

Chlamydia

Chlamydial Infection

Chlamydia Trachomatis Infectious Disease

Chlamydial Disease

Chlamydia Infections

Type 1 Diabetes Mellitus 22

Diabetes Mellitus, Insulin-Dependent, 22

IDDM22

T1D22

Insulin-Dependent Diabetes Mellitus 22

Diabetes Mellitus, Insulin-Dependent, Type 22

Oral Lichen Planus

Oral Lichenoid Lesions

Lichen Planus Oral

Lichen Planus, Oral

Coccidiosis

Intestinal Coccidiosis

Enteric Coccidiosis

Plague

Yersiniosis

Yersinia Infections

Infection By Yersinia Pestis

Pasteurella Pestis Infection

Pestilential Fever

Yersinia Pestis Infection

Intermediate Uveitis

Uveitis, Intermediate

Chronic Cyclitis

Peripheral Uveoretinitis

Iu

Uveitis Intermediate

Immune Deficiency Disease

Immunodeficiency

Primary Immunodeficiency Disease

Primary Immunodeficiency

Immunologic Deficiency Syndromes

Hypoimmunity

Immune Deficiency Disorder

Immunodeficiency Syndrome

Immune Disorder

Primary Immune Deficiency Disorder

Immune System Diseases

Human Immunodeficiency Virus Infection

Hiv - [Human Immunodeficiency Virus Infection]

Hiv Positive Nos

Hiv Disease

Acquired Immune Deficiency Syndrome-Related Complex

Aids-Like Syndrome

Aids-Related Complex Nos

Arc - [Aids-Related Complex]

Immunodeficiency Due To Human Immunodeficiency Virus Infection

Unspecified Human Immunodeficiency Virus Disease

Hiv Disease Nos

Human Immunodeficiency Virus Positive Nos

Hiv Nos

Deficiency Of Complement Initial Pathway

Deficiency Of Complement Terminal Pathway

Cfdd - [Complement Factor D Deficiency]

Immunodeficiency With Nk-Cell - [Natural-Killer Cell] Deficiency

Nonfamilial Hypogammaglobulinaemia

Common Variable Immune Deficiency

Nonfamilial Agammaglobulinaemia

Common Variable Agammaglobulinaemia

Agammaglobulinaemia Nos

Agammaglobulinaemia Antibody Deficiency Syndrome

Hypogammaglobulinaemia Antibody Deficiency Syndrome

Acquired Agammaglobulinaemia Nos

Hypogammaglobulinaemia Nos

Hyper Igm

Whiplash
Skin Disease

Skin Diseases

Abnormality Of The Skin

Skin Diseases, Genetic

Genodermatosis

Skin And Subcutaneous Tissue Disease

Dermatologic Disorders

Chronic Inflammatory Demyelinating Polyradiculoneuropathy

Chronic Inflammatory Demyelinating Polyneuropathy

Cidp

Polyradiculoneuropathy Chronic Inflammatory Demyelinating

Polyradiculoneuropathy, Chronic Inflammatory Demyelinating

Herpes Zoster

Shingles

Zoster

Herpes Zona

Herpes Zoster Disease

Zona Zoster

Herpes Zoster Of Skin And Mucous Membranes

Zoster Nos

Zoster With Nervous System Involvement

Periapical Granuloma

Apical Granuloma

Pulmonary Hypertension

Primary Pulmonary Hypertension

Hypertension Pulmonary

Hypertension, Pulmonary

Idiopathic Pulmonary Hypertension

Idiopathic Pulmonary Arterial Hypertension

Pulmonary Htn - [Hypertension]

Cholangitis

Acute Cholangiolitis

Ascending Cholangitis

Cholangiolitis

Cholangitis Nos

Chronic Cholangiolitis

Hepatic Duct Inflammation

Acute Cholangitis

Bile Duct Inflammation

Toxoplasmosis

Disseminated Toxoplasmosis

Multisystemic Disseminated Toxoplasmosis

Acquired Toxoplasmosis

Toxoplasmosis Disease Or Disorder

Infection By Toxoplasma Gondii

Toxoplasmal

Toxoplasma

West Nile Virus

West Nile Virus, Susceptibility To

Wnv

Wnv, Susceptibility To

West Nile Viral Infection

Encephalitis, West Nile Fever

West Nile Fever

Cytomegalovirus Retinitis

Cmv Retinitis

Factor Xi Deficiency

Plasma Thromboplastin Antecedent Deficiency

Rosenthal Syndrome

Pta Deficiency

Hemophilia C

Rosenthal Factor Deficiency

F11 Deficiency

Congenital Factor Xi Deficiency

Hereditary Factor Xi Deficiency Disease

Factor Xi Deficiency, Autosomal Dominant

Rosenthal'S Disease

Factor 11 Deficiency

Haemophilia C

Factor Xi Deficiency, Autosomal Recessive

Factor Xi Deficiency, Congenital

FA11D

Factor Xi

Thromboplastin Antecedent Deficiency

Pta - [Plasma Thromboplastin Antecedent] Deficiency

Congenital Factor Xi Deficiency Disease

Rosenthal Disease

Neuritis

Peripheral Neuritis

Uveitis
Optic Neuritis

Inflammatory Optic Neuropathy

Chancroid

Ulcus Molle, Skin

Chancroids

Bubo Due To Haemophilus Ducreyi

Soft Chancre

Ulcus Molle

Autoimmune Disease

Autoimmune Diseases

Autoimmune Hypersensitivity Disease

Hypersensitivity Reaction Type Ii Disease

Type Ii Hypersensitivity Reaction Disease

Syphilis

Chancre

Syphilitic Chancre

Diabetes Mellitus

Diabetes

Systemic Lupus Erythematosus

Lupus Nephritis

SLE

Disseminated Lupus Erythematosus

Systemic Lupus Erythematosus, Susceptibility To

Lupus Erythematosus, Systemic

Lupus Nephritis, Susceptibility To

Libman-Sacks Disease

Systemic Lupus Erythematosus Susceptibility To

Sle - Lupus Erythematosus, Systemic

Le Syndrome

Lupus

Lupus Erythematosus Systemic

Lupus Erythematosus, Systemic, Susceptibility To

Lupus Vulgaris

Lupus Erythematosus, Discoid

Lupus Erythematosus

Systemic Lupus Erythematosus Nos

Sle - [Systemic Lupus Erythematosus]

Disease By Infectious Agent

Infectious Disease

Infectious Diseases

Secondary Syphilis

Syphilis, Secondary

Secondary Syphilis Of Viscera Or Bone

Asthma

Chronic Obstructive Asthma

Asthma, Diminished Response To Antileukotriene Treatment In

Bronchial Hyperreactivity

Asthma, Susceptibility To

Asthma, Bronchial

Asthma, Protection Against

Asthma, Nocturnal, Susceptibility To

Nocturnal Asthma

Asthma-Related Traits

Asthma-Related Traits, Susceptibility To

Asthma, Nocturnal

Chronic Obstructive Asthma With Acute Exacerbation

Chronic Obstructive Asthma With Status Asthmaticus

Exercise Induced Asthma

Exercise-Induced Asthma

Bronchial Asthma

Asthma, Exercise-Induced

Idiosyncratic Asthma

Unspecified Asthma With Acute Exacerbation

Asthma, Unspecified, With Stated Status Asthmaticus

Status Asthmaticus Nos

Acute Severe Asthma

Acute Severe Bronchial Asthma

Status Asthma

Status Post Asthmaticus

Viral Infectious Disease

Arbovirus Infections

Viral Disease

Virus Infection

Virus Diseases

Viral Infection

Viral Infections

Virus Infections

Hepatitis A

Viral Hepatitis A

Viral Hepatitis, Type A

Opioid Abuse

Opioid-Related Disorders

Leukemia, Acute Myeloid

Acute Myeloid Leukemia

Leukemia, Acute Myelogenous

Acute Myelogenous Leukemia

AML

Leukemia, Acute Myeloid, Susceptibility To

Acute Myeloblastic Leukemia

Leukemia, Acute Myeloid, Reduced Survival In, Somatic

Acute Myeloid Leukaemia

Leukemia, Myelocytic, Acute

Therapy Related Acute Myeloid Leukemia And Myelodysplastic Syndrome

Secondary Aml

Acute Myelocytic Leukemia

Leukemia, Myeloid, Acute

Acute Myeloid Leukemia, Somatic

Leukemia, Acute Myeloid, Somatic

Myeloid Leukemia, Acute, M4/M4eo Subtype, Somatic

Acute Myeloblastic Leukaemia

Acute Myelogenous Leukaemia

Aml - Acute Myeloid Leukemia

Acute Myeloid Leukemia With Cebpa Somatic Mutations

Aml With Cebpa Somatic Mutations

Inherited Acute Myeloid Leukemia

Familial Aml

Inherited Aml

Pure Familial Aml

Pure Familial Acute Myeloid Leukemia

Secondary Acute Myeloid Leukemia

Therapy-Related Aml And Myelodysplastic Syndrome

Acute Myeloid Leukemia, Secondary

Acute Non-Lymphoblastic Leukemia

Acute Non-Lymphocytic Leukemia

Acute Biphenotypic Leukemia

Acute Undifferentiated Leukemia

Acute Myeloblastic Leukaemia With Multilineage Dysplasia

Acute Myeloid Leukaemia With Multilineage Dysplasia Without Mention Of Remission

Acute Myeloid Leukaemia With Myelodysplasia-Related Features

Chagas Disease

American Trypanosomiasis

Chagas' Disease

Chagas' Disease With Digestive System Involvement

Chagas' Disease With Nervous System Involvement

Chagas' Disease With Other Organ Involvement

Infection Due To Trypanosoma Cruzi

South American Trypanosomiasis

Chronic Chagas Disease With Digestive System Involvement

Genital Herpes

Herpes Genitalis

Genital Herpes Simplex

Venereal Herpes

Virus-Genital Herpes

Trichomoniasis

Trichomonas Infection

Trichomonas Infections

Disease Due To Trichomonadidae

Infection By Trichomonas

Trichomonadosis

Trichomonas Pruritus

Trichomonosis

Tricomoniasis

Arteriosclerosis

Arteriosclerotic Vascular Disease

Ebola Hemorrhagic Fever

Ebola Virus Disease

Viral Hemorrhagic Fever

Hemorrhagic Fever, Ebola

Ehf

Ebola Fever

Ebola

Hemorrhagic Fevers, Viral

Ebola Haemorrhagic Fever

Ebod - [Ebola Disease]

Evd - [Ebola Virus Disease]

Ebola Virus Haemorrhagic Fever

Vhf - [Viral Haemorrhagic Fever] Nos

Viral Haemorrhagic Fever, Not Otherwise Specified

Myocardial Infarction

Heart Attack

Myocardial Infarction, Susceptibility To

Myocardial Infarction 1

Myocardial Infarction, Protection Against

Myocardial Infarction, Decreased Susceptibility To

Myocardial Infarction, Decreased

Myocardial Infarct

MCI1

Premature Myocardial Infarction

Myocardial Infarction, Susceptibility To, Type 1

Granulomatosis With Polyangiitis

GPA

Wegener Granulomatosis

Wegener Granulomatosis, Formerly

Midline Granulomatosis

Wg, Formerly

Necrotizing Respiratory Granulomatosis

Wg

Wegeners Granulomatosis

Pauci-Immune Glomerulonephritis Associated With Granulomatosis With Polyangiitis

Pulmonary Disease, Chronic Obstructive

Chronic Obstructive Pulmonary Disease

COPD

Pulmonary Disease, Chronic Obstructive, Severe Early-Onset

Chronic Obstructive Lung Disease

Chronic Obstructive Airway Disease

Pulmonary Disease, Chronic Obstructive, Susceptibility To

Cold

Severe Early-Onset Chronic Obstructive Pulmonary Disease

Pulmonary Disease Chronic Obstructive

Pulmonary Disease, Obstructive, Chronic, Susceptibility To

Chronic Obstructive Pulmonary Disease Of Horses

Common Cold

Upper Respiratory Infections

Copd - [Chronic Obstructive Pulmonary Disease]

Coad - [Chronic Obstructive Airways Disease]

Cold - [Chronic Obstructive Lung Disease]

Chronic Airway Disease Nos

Chronic Airways Limitation, Unspecified

Chronic Obstructed Airway, Unspecified

Chronic Obstructive Airway Disease, Unspecified

Chronic Obstructive Airway, Unspecified

Obstructive Lung Disease Nos

Chronic Obstructive Lung Disease Nos

Chronic Obstructive Lung Nos

Obstructive Pulmonary Disease Nos

Exacerbation Copd Nos

Acute Exacerbation Copd

Multiple Sclerosis

MS

Multiple Sclerosis, Susceptibility To

Disseminated Sclerosis

Multiple Sclerosis, Disease Progression, Modifier Of

Insular Sclerosis

Multiple Sclerosis Modifier Of Disease Progression

Multiple Sclerosis, Susceptibility To 1

Multiple Sclerosis, Susceptibility To, 1

Multiple Sclerosis 1

Generalized Multiple Sclerosis

Multiple Sclerosis Variant

Multiple Sclerosis Susceptibility To

Cerebrospinal Sclerosis

Generalised Multiple Sclerosis

Ms - [Multiple Sclerosis]

Disseminated Cerebrospinal Sclerosis

Disseminated Multiple Sclerosis

Disseminated Nervous System Myelosclerosis

Multiple Cerebrospinal Sclerosis

Multiple Combined Sclerosis

Multiple Sclerosis Generalised

Disseminated Brain Sclerosis

Disseminated Spinal Sclerosis

Insular Brain Sclerosis

Miliary Brain Sclerosis

Multiple Combined Sclerosis Of Spinal Cord

Multiple Ascending Sclerosis

Multiple Brain Sclerosis

Multiple Sclerosis Of Brain Stem

Multiple Sclerosis Of The Brain Stem

Multiple Sclerosis Of Cord

Sclérose En Plaques

Plaque Sclerosis

Multiple Sclerosis Of The Spinal Cord

Vas Deferens, Congenital Bilateral Aplasia Of

Congenital Bilateral Absence Of Vas Deferens

CBAVD

Cavd

Congenital Bilateral Aplasia Of Vas Deferens

Congenital Bilateral Absence Of The Vas Deferens

Congenital Bilateral Agenesis Of Vas Deferens

Absence Of Vas Deferens

Absent Vasa

Congenital Absence Of Vas Deferens

Congenital Aplasia Of Vas Deferens

Absent Vas Deferens

Vas Deferens, Congenital Bilateral Absence

Tick-Borne Encephalitis

Siberian Tick-Borne Encephalitis

Encephalitis, Tick-Borne

Central European Encephalitis

Far Eastern Tbe

Russian Spring-Summer Encephalitis

Taiga Encephalitis

West-Siberian Encephalitis

Western European Tick-Borne Encephalitis

Tbe

Encephalitis Tick-Borne

Encephalitis, Central European

Encephalitis, Far Eastern Russian

Human Immunodeficiency Virus Type 1

Aids

Hiv/Aids

Aids, Delayed/Rapid Progression To

Hiv-1, Susceptibility To

Hiv-1 Viremia, Susceptibility To

Human Immunodeficiency Virus Type 1, Susceptibility To

Hiv-1

Aids, Slow Progression To

Rapid Progression To Aids From Hiv1 Infection

Hiv1 Infection, Resistance To

Hiv1 Infection

Hiv-1 Viremia

Aids, Resistance To

Aids, Rapid Progression To

Hiv/Aids, Susceptibility To

Hiv-1, Resistance To

Hiv1, Resistance To

Hiv1

Hiv-1 Disease, Delayed Progression Of

Hiv-1 Disease, Rapid Progression Of

Hiv Infection, Resistance To

Hiv Type 1, Susceptibility To

Hiv Type 1

Hiv-1 Infection

Human Immunodeficiency Virus I Infection

Acquired Immunodeficiency Syndrome

Hiv-Infection/Aids

Abacavir Allergy

Abc Allergy

Vaccinia
Sickle Cell Anemia

Hemoglobin Sc Disease

Anemia, Sickle Cell

Hbsc Disease

Sickle Cell-Hemoglobin C Disease Syndrome

Hb Ss Disease

Sickle Cell Trait

Drepanocytosis

Haemoglobin Sc Disease

Hb Sc Disease

Hb-S/Hb-C Disease

Hb-Ss Disease Without Crisis

Hemoglobin S Disease Without Crisis

Sickle Cell Anaemia

Sickle-Cell/Hb-C Disease Without Crisis

Sickle Cell - Hemoglobin C Disease

Hbs Disease

Hemoglobin S Disease

Sickling Disorder Due To Hemoglobin S

SKCA

Sickle Cell Disease

Sickle Cell-Hemoglobin C Disease

Sickle-Cell Disease Carrier

Sickle-Cell Heterozygous Disorder

Haemoglobin A-S Genotype

Hb-S - [Sickle Cell Haemoglobin] Carrier

Sickle Cell Haemoglobin Trait

As - [Sickle Cell Trait]

Hbas - [Sickle Cell Haemoglobin Trait]

Sickle-Cell Trait Haemoglobin Disease

Haemoglobin Sickle Cell Trait Disorder

Heterozygous Sickle Cell Trait

Hbas - [Heterozygous Haemoglobin S]

Keratoconjunctivitis
Dementia

Dementias

Presenile Dementia

Alzheimer Type Dementia

Alzheimer Sclerosis

Alzheimer Disease Dementia

Alzheimer Dementia

Primary Degenerative Alzheimer Type Dementia

End Stage Alzheimer'S Dementia

Alzheimer'S Type Atypical Dementia

Alzheimer Type Presenile Dementia

Early Onset Alzheimer Dementia

Dementia In Alzheimer Disease Type 2

Dementia In Alzheimer Disease With Early Onset

Early Onset Alzheimer Type Dementia, Uncomplicated

Primary Degenerative Alzheimer Type Dementia, Early Onset

Primary Degenerative Alzheimer Type Dementia, Presenile Onset, Uncomplicated

Alzheimer Disease Dementia With Early Onset

Presenile Sclerosis

Presenile Brain Sclerosis

Presenile Alzheimer Brain Sclerosis

Late Onset Alzheimer Dementia

Dementia In Alzheimer Disease Type 1

Dementia In Alzheimer Disease With Late Onset

Primary Degenerative Alzheimer Type Dementia, Late Onset

Sdat - [Senile Dementia, Alzheimer Type]

Alzheimer Disease Dementia With Late Onset

Late Onset Alzheimer Brain Sclerosis

Senile Alzheimer Brain Disease

Senile Alzheimer Brain Sclerosis

Senile Primary Degenerative Alzheimer Type Dementia

Senile Dementia Of The Alzheimer Type

Arteriosclerotic Dementia

Strategic-Infarct Dementia

Post Stroke Dementia

Vascular Cognitive Impairment

Vascular Dementia

Dementia Of The Lewy Body Type

Dementia With Lewy Bodies

Sdlt - [Senile Dementia Of The Lewy Body Type]

Senile Dementia Of The Lewy Body Type

Alcohol-Related Dementia

Alcoholic Dementia Nos

Alcohol-Induced Dementia

Alcoholic Brain Syndrome

Chronic Alcoholic Brain Syndrome

Alcohol Dementia

Late Onset Alcoholic Psychosis

Residual And Late-Onset Alcohol-Induced Psychotic Disorder

Mental And Behavioural Disorders Due To Use Of Sedatives Or Hypnotics, Residual And Late-Onset Psychotic Disorder

Late-Onset Psychoactive Substance-Induced Psychotic Disorder

Inhalant Dementia

Volatile Solvents Dementia

Dementia In Paralysis Agitans

Pdd - [Parkinson Disease Dementia]

Dementia Syndrome Of Parkinson Disease

Dementia In Parkinson Disease

Parkinson Related Dementia

Dementia In Huntington Chorea

Hiv - [Human Immunodeficiency Virus] Dementia

Hiv- [Human Immunodeficiency Virus] Associated Cognitive Motor Complex

Hiv- [Human Immunodeficiency Virus] Associated Dementia Complex

Aids - [Acquired Immunodeficiency Syndrome] Dementia Complex

Aids Related Dementia

Dementia Due To Niacin Deficiency

Fallopian Tube Disease

Fallopian Tube Diseases

Acquired Immunodeficiency Syndrome

Acquired Immune Deficiency Syndrome

AIDS

Acquired Immune Deficiency

Acquired Immunodeficiency

Acquired Immunodeficiency Due To Protein Loss

Progressive Multifocal Leukoencephalopathy

Pml

Leukoencephalopathy, Progressive Multifocal

Progressive Multifocal Leukoencephalitis

Leukoencephalopathy Progressive Multifocal

Pml - [Progressive Multifocal Leukoencephalopathy]

West Nile Fever
Vaginal Disease

Vaginal Diseases

Nervous System Disease

Abnormality Of The Nervous System

Nervous System Diseases

Nervous System Disorder

Type 1 Diabetes Mellitus

Diabetes Mellitus, Insulin-Dependent

Diabetes Mellitus Type 1

IDDM

Insulin-Dependent Diabetes Mellitus

Type 1 Diabetes

T1D

Juvenile-Onset Diabetes

Jod

Diabetes Mellitus, Type 1

Diabetes Mellitus, Insulin-Dependent-1

Type I Diabetes Mellitus

Autoimmune Diabetes

Juvenile Diabetes

Juvenile-Onset Diabetes Mellitus

Diabetes, Insulin Dependent

Insulin-Dependent Diabetes Mellitus-1

Diabetes Mellitus Insulin-Dependent

Diabetes Autoimmune

Diabetes Mellitus, Insulin-Dependent, Susceptibility To

Diabetes Mellitus, Type 1, Susceptibility To

Diabetes Type 1

Type I Diabetes

Diabetes, Autoimmune

T1dm - [Type 1 Diabetes Mellitus]

Iddm - [Insulin Dependent Diabetes Mellitus]

Type 1 Iddm

Juvenile Diabetes Mellitus Without Compications

Idiopathic Insulin-Dependent Diabetes Mellitus Without Complications

Juvenile-Onset Diabetes Mellitus Without Compications

Ketosis-Prone Diabetes Mellitus Without Compications

Juvenile-Onset-Type Diabetes Mellitus Without Compications

Inflammatory Bowel Disease

Inflammatory Bowel Diseases

Bowel Disease, Inflammatory

Pulmonary Sarcoidosis

Sarcoidosis, Pulmonary

Lung Sarcoidosis

Sarcoidosis Pulmonary

Lung Sarcoid

Sarcoidosis In Lung

Vaginitis

Infective Vaginitis

Inflammation Of Vagina

Colpitis

Vaginal Inflammation

Vaginitis Nos

Behcet Syndrome

Behcet Disease

Behcet'S Syndrome

Behcet'S Disease

Behçet Disease

Bd

Adamantiades-Behcet Disease

Triple Symptom Complex

Behet'S Syndrome

Bd Syndrome

Behçet Syndrome

Behçet'S Disease

Behçet'S Syndrome

Behcet Triple Symptom Complex

Malignant Aphthosis

Old Silk Route Disease

Adamantiades-Behçet Disease

Hepatitis C Virus

Hepatitis C Virus, Susceptibility To

Hepatitis C Virus Infection, Response To Therapy Of

Hcv

Hcv, Susceptibility To

Hepatitis C Virus, Resistance To

Hepatitis C Virus, Response To Therapy Of

Resistance To Hepatitis C Virus

Sarcoidosis 1

Sarcoidosis

Boeck Sarcoid

Besnier-Boeck-Schaumann Disease

SS1

Sarcoidosis, Susceptibility To, 1

Lymphogranulomatosis

Hodgkin Disease

Boeck'S Disease

Boeck'S Sarcoid

Schaumann'S Disease Or Syndrome

Hutchinson-Boeck Disease Or Syndrome

Substance Abuse

Substance-Related Disorders

Substance Abuse Problem

Ileitis

Crohn'S Ileitis

Hypertension, Essential

Essential Hypertension

Hypertension

High Blood Pressure

Hypertension, Essential, Susceptibility To

Hypertensive Disease

Primary Hypertension

EHT

Hypertension, Salt-Sensitive Essential, Susceptibility To

Hyperpiesia

Idiopathic Hypertension

Hypertensive Disorder

Hypertension, Essential, Susceptibility To, 3

Hypertension, Essential 3

Hypertension, Essential, Salt-Sensitive

Hypertension, Essential, Susceptibility To, 6

Hypertension, Essential 6

Hypertension, Salt-Sensitive Essential

Hypertension, Susceptibility To

Hypertension, Essential, Susceptibility To, 4

Hypertension, Essential 4

Hypertension, Essential, Susceptibility To, 2

Hypertension, Essential 2

Hypertension, Essential, Susceptibility To, 1

Hypertension, Essential 1

Hypertension, Essential, Susceptibility To, 5

Hypertension, Essential 5

Htn

Vascular Hypertensive Disorder

Systemic Primary Arterial Hypertension

Hbp - [High Blood Pressure]

Systemic Arterial Hypertensive Disorder

Elevated Blood Pressure

Arterial Hypertension Nos

Hypertension Nos

Benign Hypertension

Systemic Arterial Hypertension

Systemic Hypertension

Artery Htn

Benign Htn

Vascular Htn

Vascular Hypertension

Cholesterol Hypertension

Cholesterol Htn

Idiopathic Htn

Malignant Hypertension

Malignant Htn

Raised Blood Pressure

Cardiovascular Hypertension

Primary Htn - [Hypertension]

High Arterial Tension

High Blood Pressure Disorder

Ht - [Hypertension]

Htn - [Hypertension]

Hypertensive Vascular Disease

Hypertensive Vascular Degeneration

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Canis familiaris CCR5 VGNC VGNC:57305
Rattus norvegicus CCR5 RGD RGD:620596
Mus musculus CCR5 MGD MGI:107182
Macaca mulatta CCR5 VGNC VGNC:84217
Others CCR5 NCBI