2. Gene
  3. Ldha - lactate dehydrogenase A Gene

Ldha - lactate dehydrogenase A Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Ldh1; Ldhm; l7R2

Gene ID: 16828 | Gene type: protein coding

About Ldha

Summary

The protein encoded by this gene catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. The protein is found predominantly in muscle tissue and belongs to the Lactate Dehydrogenase family. Mutations in this gene have been linked to hemolytic anemia and early postimplantation death in mice. Multiple transcript variants encoding different isoforms have been found for this gene. The mouse genome contains multiple pseudogenes of this gene. [provided by RefSeq, May 2013]

Ldha Products(2)

mRNA Protein Name
NM_001136069.2 NP_001129541.2 L-lactate dehydrogenase A chain isoform 2
NM_010699.2 NP_034829.1 L-lactate dehydrogenase A chain isoform 1
Protein Preferred Names Protein Names

L-lactate dehydrogenase A chain

LDH muscle subunit

LDH-M

M-LDH

lactate dehydrogenase 1, A chain

lactate dehydrogenase A4

Recombinant Ldha Proteins

Cat. No. Product Name Accession Purity
HY-P70259 LDHA Protein, Mouse (HEK293, His) P06151 (M1-F332) ≥95%
HY-P73270 LDHA Protein, Mouse (His) P06151 (M1-F332) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (21)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-W013032A Oxamic acid sodium 99.72% Unkown
HY-100681 GSK2837808A Inhibitor ≥99.0% Unkown
HY-16214 FX-11 99.11% Unkown
HY-100742A (R)-GNE-140 Inhibitor 98.01% Unkown
HY-W040118 Galloflavin Inhibitor 99.36% Unkown
HY-139319 LDHA-IN-3 Inhibitor 99.81% Unkown
HY-18968 LDHA-IN-4 Inhibitor 98.06% Unkown
HY-100742 GNE-140 racemate Inhibitor 99.38% Unkown
HY-111108 LDH-IN-1 Inhibitor 99.86% Unkown
HY-124309 NHI-2 Inhibitor 99.30% Unkown
HY-147361 LDCA 99.18% Unkown
HY-156683 CHK-336 Inhibitor 98.05% Unkown
HY-100742B (S)-GNE-140 Inhibitor 99.07% Unkown
HY-152261 MS6105 / Unkown
HY-115875 LDHA-IN-5 Inhibitor / Unkown
HY-146977 LDHA/PDKs-IN-1 Inhibitor / Unkown
HY-146978 LDHA/PDKs-IN-2 Inhibitor / Unkown
HY-162627 LDHA-IN-6 Inhibitor / Unkown
HY-162629 LDHA-IN-7 Inhibitor / Unkown
HY-169060 LDHA-IN-8 Inhibitor / Unkown
HY-RS07571 LDHA Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ldha NCBI NCBI:3939
Rattus norvegicus Ldha NCBI NCBI:24533