2. Gene
  3. Prl - prolactin Gene

Prl - prolactin Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Gha1; Prl1a1

Gene ID: 19109 | Gene type: protein coding

About Prl

Summary

Predicted to enable hormone activity and Prolactin receptor binding activity. Acts upstream of or within several processes, including mammary gland development; maternal behavior; and positive regulation of receptor signaling pathway via JAK-STAT. Located in secretory granule. Is expressed in hippocampus; pituitary gland; placenta; and trophoblast giant cell. Human ortholog(s) of this gene implicated in carotid artery disease. Orthologous to human PRL (Prolactin). [provided by Alliance of Genome Resources, Apr 2022]

Prl Products(2)

mRNA Protein Name
NM_001163530.1 NP_001157002.1 prolactin isoform 2 precursor
NM_011164.2 NP_035294.2 prolactin isoform 1 precursor
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
acts upstream of cell population proliferation IGI
IGI: Inferred from genetic interaction
9247268 MGI
acts upstream of epithelial cell proliferation IGI
IGI: Inferred from genetic interaction
9247268 MGI
acts upstream of or within mammary gland development IGI
IGI: Inferred from genetic interaction
18425773 MGI
acts upstream of or within maternal behavior IGI
IGI: Inferred from genetic interaction
23071095 MGI
acts upstream of or within positive regulation of cell population proliferation IGI
IGI: Inferred from genetic interaction
9247268 MGI
acts upstream of or within positive regulation of epithelial cell proliferation IGI
IGI: Inferred from genetic interaction
9247268 MGI
acts upstream of or within positive regulation of receptor signaling pathway via JAK-STAT IGI
IGI: Inferred from genetic interaction
12388746 MGI
acts upstream of or within regulation of receptor signaling pathway via JAK-STAT IDA
IDA: Inferred from direct assay
12147240 MGI
Cellular Component GO Annotation Evidence Reference Source
located in secretory granule IDA
IDA: Inferred from direct assay
9247267 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

prolactin

growth hormone a1

Recombinant Prl Proteins

Cat. No. Product Name Accession Purity
HY-P73381 Prolactin Protein, Mouse (Sf9, His) NP_035294.2 (L32-C228) ≥95%
HY-P700261 Prolactin Protein, Mouse (His) P06879 (L30-C226) ≥95%

Related Agents

Approval
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-B0537B Pentamidine isethionate Inhibitor 99.92% Yes
HY-B0537 Pentamidine Inhibitor 97.19% Yes
HY-B0537C Pentamidine dimesylate Inhibitor / Unkown
HY-B0537A Pentamidine dihydrochloride Inhibitor / Unkown
Pre-clinical Phase
Bioactive Molecules (12)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-128153 Thienopyridone 98.05% Unkown
HY-112476 PRL-3 Inhibitor I Inhibitor 99.10% Unkown
HY-P4452 PRL 2915 99.57% Unkown
HY-W043170 PRL3-CNNM4 interaction-IN-1 Inhibitor 99.33% Unkown
HY-103079 PRL-3 Inhibitor 2 Inhibitor ≥98.0% Unkown
HY-131547 Org OD 02-0 99.7% Unkown
HY-P4469 PRL 3195 / Unkown
HY-162119 PRL-IN-1 Inhibitor / Unkown
HY-P4523 FA-Ala-Arg / Unkown
HY-RS11160 PRL Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-114877 CG-707 Inhibitor / Unkown
HY-171035 PRL-295 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Prl NCBI NCBI:5617
Canis familiaris Prl NCBI NCBI:488241
Macaca fascicularis Prl NCBI NCBI:102133150
Susscrofa domestica Prl NCBI
Rattus norvegicus Prl NCBI NCBI:24683