2. Gene
  3. Cxcl12 - chemokine (C-X-C motif) ligand 12 Gene

Cxcl12 - chemokine (C-X-C motif) ligand 12 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Pbsf; Sdf1; Tlsf; Tpar1; Scyb12

Gene ID: 20315 | Gene type: protein coding

About Cxcl12

Summary

This gene encodes a member of the alpha chemokine protein family. The encoded protein is secreted and functions as the ligand for the G-protein coupled receptor, chemokine (C-X-C motif) receptor 4. The encoded protein plays a role in many diverse cellular functions, including embryogenesis, immune surveillance, inflammation response, tissue homeostasis, and tumor growth and metastasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]

Cxcl12 Products(3)

mRNA Protein Name
NM_001012477.2 NP_001012495.1 stromal cell-derived factor 1 isoform gamma precursor
NM_013655.4 NP_038683.1 stromal cell-derived factor 1 isoform beta precursor
NM_021704.3 NP_068350.1 stromal cell-derived factor 1 isoform alpha precursor
Protein Preferred Names Protein Names

stromal cell-derived factor 1

12-O-tetradecanoylphorbol 13-acetate repressed protein 1

pre-B-cell growth-stimulating factor

thymic lymphoma cell-stimulating factor

Recombinant Cxcl12 Proteins

Cat. No. Product Name Accession Purity
HY-P7285 SDF-1 alpha/CXCL12 Protein, Mouse P40224-1 (K22-K89) ≥95%
HY-P7403 SDF-1 alpha/CXCL12 Protein, Mouse (68a.a, CHO) P40224-1 (K22-K89) ≥95%
HY-P72782 SDF-1 beta/CXCL12 Protein, Mouse P40224-2 (K22-M93) ≥95%
HY-P700219AF Animal-Free SDF-1 alpha/CXCL12 Protein, Mouse (His) P40224 (G21-K89) ≥95%

Related Agents

Clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Phase
HY-114244 USL311 Antagonist 99.97% Phase 2
HY-13696 MSX-122 Antagonist 98.92% Phase 1
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P99272 Ulocuplumab Antagonist 99.90% Phase 3
Pre-clinical Phase
Bioactive Molecules (25)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-142617 ACT-1004-1239 Antagonist 99.80% Yes
HY-110318 VUF11207 fumarate Agonist 98.50% Unkown
HY-101458A IT1t dihydrochloride 99.77% Unkown
HY-139643 CXCR7 antagonist-1 Antagonist 99.97% Unkown
HY-15478 WZ811 Antagonist 99.79% Unkown
HY-15971 AMD 3465 hexahydrobromide ≥98.0% Unkown
HY-139643A CXCR7 antagonist-1 hydrochloride Antagonist 99.66% Unkown
HY-P1103 CTCE-9908 Antagonist 99.69% Unkown
HY-15971A AMD 3465 99.59% Unkown
HY-112709 LIT-927 99.86% Unkown
HY-101458 IT1t / Unkown
HY-N3255 Minecoside Inhibitor 99.86% Unkown
HY-160041 Olaptesed pegol Inhibitor / Unkown
HY-160041A Olaptesed pegol sodium Inhibitor / Unkown
HY-129094 ICT5040 Antagonist / Unkown
HY-131374 TN14003 Inhibitor / Unkown
HY-139906 CXCL12 ligand 1 Inhibitor / Unkown
HY-146372 CXCR4 antagonist 5 Antagonist / Unkown
HY-146401 CXCR4 antagonist 6 Antagonist / Unkown
HY-147978 CXCR4 antagonist 8 Antagonist / Unkown
HY-147979 CXCR4 antagonist 9 Antagonist / Unkown
HY-168095 CXCR4 antagonist 10 Inhibitor / Unkown
HY-P10415 EPI-X4 Antagonist / Unkown
HY-P1103A CTCE-9908 TFA Antagonist / Unkown
HY-RS03386 CXCL12 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cxcl12 NCBI NCBI:6387
Canis familiaris Cxcl12 NCBI NCBI:449622
Rattus norvegicus Cxcl12 NCBI NCBI:24772