2. Gene
  3. Tpo - thyroid peroxidase Gene

Tpo - thyroid peroxidase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus
Gene ID: 22018 | Gene type: protein coding

About Tpo

Summary

This gene encodes a membrane-bound glycoprotein. The encoded Enzyme plays a central role in thyroid gland function. The Enzyme functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid Hormones, thyroxine and triiodothyronine. Mice with homozygous missense mutations in this gene exhibit hypothyroid dwarfism and hearing impairment. [provided by RefSeq, Sep 2015]

Tpo Products(1)

mRNA Protein Name
NM_009417.3 NP_033443.1 thyroid peroxidase precursor
Protein Preferred Names Protein Names

thyroid peroxidase

Recombinant Tpo Proteins

Cat. No. Product Name Accession Purity
HY-P78045 TPO/Thyroid Peroxidase Protein, Mouse (HEK293, His) P35419 (G32-R834) ≥95%

Related Agents

Approval
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-19883 Lusutrombopag Agonist 98.88% Unkown
HY-13463 Avatrombopag Agonist 99.83% Yes
HY-W017113 2-Mercaptobenzothiazole Activator 99.85% Yes
HY-13463B Avatrombopag hydrochloride Agonist 96.69% Yes
HY-13463A Avatrombopag maleate Agonist 99.88% Yes
Clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-145589 Rafutrombopag Agonist / Phase 1
Pre-clinical Phase
Bioactive Molecules (12)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-148748 Butyzamide Activator 99.62% Unkown
HY-112486 TA-316 98.04% Unkown
HY-W017894 TPO-L 99.40% Unkown
HY-100380 TPO agonist 1 Agonist ≥98.0% Unkown
HY-139915 MPO-IN-1 Inhibitor 99.02% Unkown
HY-15306S Eltrombopag-13C4 97.89% Unkown
HY-112486G TA-316 (GMP) Agonist / Unkown
HY-19883S Lusutrombopag-d13 Agonist 98.64% Unkown
HY-13463BS Avatrombopag-d8 hydrochloride Agonist / Unkown
HY-147691 MPO-IN-5 Inhibitor / Unkown
HY-153239 Eltrombopag methyl ester Agonist / Unkown
HY-RS14941 TPO Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tpo NCBI NCBI:7173
Macaca fascicularis Tpo NCBI NCBI:102125126
Rattus norvegicus Tpo NCBI NCBI:54314