KRT79 - keratin 79 Gene

Homo sapiens

Also known as K6L; KRT6L

Gene ID: 338785 | Gene type: protein coding

About KRT79

Cytogenetic location: 12q13.13 Genomic coordinates (GRCh38): 12:52,821,408-52,834,311 (from NCBI)

This gene has 3 transcripts (splice variants), 84 orthologues and 68 paralogues. Biased expression in skin (RPKM 6.3), fat (RPKM 0.8) and 1 other tissue.

Summary

Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins. This gene encodes an epithelial keratin that is expressed in skeletal muscle, skin and scalp. The type II keratins are clustered in a region of chromosome 12q13.[provided by RefSeq, Jun 2009]

KRT79 Products(1)

mRNA	Protein	Name
NM_175834.3	NP_787028.1	keratin, type II cytoskeletal 79

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables enzyme binding	IPI IPI: Inferred from physical interaction	23382074	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	25416956	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

KRT79 Protein Structure

Filament

0
100
200
300
400
500
535 a.a.

Protein Preferred Names

Protein Names

keratin, type II cytoskeletal 79

CK-79

KRT79 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	KRT79	Q5XKE5	KRT13	Homo sapiens	A1A4E9	Y2H Prey Pooling	25416956
Intra	KRT79	Q5XKE5	KRT13	Homo sapiens	A1A4E9	Y2H Array	25416956
Intra	KRT79	Q5XKE5	SYCE3	Homo sapiens	A1L190	Y2H Array	32296183
Intra	KRT79	Q5XKE5	SYCE3	Homo sapiens	A1L190	Y2H Prey Pooling	32296183
Intra	KRT79	Q5XKE5	KRT34	Homo sapiens	O76011	Y2H Prey Pooling	32296183
Intra	KRT79	Q5XKE5	KRT34	Homo sapiens	O76011	Y2H Array	32296183
Intra	KRT79	Q5XKE5	KRT38	Homo sapiens	O76015	Y2H Array	25416956
Intra	KRT79	Q5XKE5	KRT38	Homo sapiens	O76015	Y2H Array	29892012
Intra	KRT79	Q5XKE5	KRT38	Homo sapiens	O76015	Validated Y2H	25416956
Intra	KRT79	Q5XKE5	KRT33B	Homo sapiens	Q14525	Y2H Prey Pooling	32296183
Intra	KRT79	Q5XKE5	KRT33B	Homo sapiens	Q14525	Y2H Array	25416956
Intra	KRT79	Q5XKE5	KRT33B	Homo sapiens	Q14525	Y2H Array	32296183
Intra	KRT79	Q5XKE5	KRT33B	Homo sapiens	Q14525	Y2H Array	31515488
Intra	KRT79	Q5XKE5	KRT35	Homo sapiens	Q92764	Y2H Array	32296183
Intra	KRT79	Q5XKE5	KRT35	Homo sapiens	Q92764	Validated Y2H	32296183
Intra	KRT79	Q5XKE5	KRT35	Homo sapiens	Q92764	Y2H Prey Pooling	32296183
Intra	KRT79	Q5XKE5	KRT36	Homo sapiens	O76013-2	Y2H Array	32296183
Intra	KRT79	Q5XKE5	KRT36	Homo sapiens	O76013-2	Y2H Prey Pooling	32296183
Intra	KRT79	Q5XKE5	KRT25	Homo sapiens	Q7Z3Z0	Y2H Prey Pooling	32296183
Intra	KRT79	Q5XKE5	KRT25	Homo sapiens	Q7Z3Z0	Validated Y2H	32296183
Intra	KRT79	Q5XKE5	KRT25	Homo sapiens	Q7Z3Z0	Y2H Array	32296183
Intra	KRT79	Q5XKE5	KRT28	Homo sapiens	Q7Z3Y7	Validated Y2H	32296183
Intra	KRT79	Q5XKE5	TRIM54	Homo sapiens	Q9BYV2	Y2H Prey Pooling	32296183
Intra	KRT79	Q5XKE5	TRIM54	Homo sapiens	Q9BYV2	Validated Y2H	32296183
Intra	KRT79	Q5XKE5	TRIM54	Homo sapiens	Q9BYV2	Y2H Array	32296183
Intra	KRT79	Q5XKE5	KRT24	Homo sapiens	Q2M2I5	Y2H Array	32296183
Intra	KRT79	Q5XKE5	KRT24	Homo sapiens	Q2M2I5	Y2H Prey Pooling	32296183
Intra	KRT79	Q5XKE5	KRT18	Homo sapiens	P05783	Y2H Array	32296183
Intra	KRT79	Q5XKE5	KRT18	Homo sapiens	P05783	Y2H Prey Pooling	32296183
Intra	KRT79	Q5XKE5	KRT27	Homo sapiens	Q7Z3Y8	Validated Y2H	32296183
Intra	KRT79	Q5XKE5	KRT27	Homo sapiens	Q7Z3Y8	Y2H Prey Pooling	32296183
Intra	KRT79	Q5XKE5	KRT27	Homo sapiens	Q7Z3Y8	Complementation	32296183
Intra	KRT79	Q5XKE5	KRT27	Homo sapiens	Q7Z3Y8	Y2H Array	32296183
Intra	KRT79	Q5XKE5	KRT16	Homo sapiens	P08779	Y2H Prey Pooling	32296183
Intra	KRT79	Q5XKE5	KRT16	Homo sapiens	P08779	Y2H Array	32296183
Intra	KRT79	Q5XKE5	KRT14	Homo sapiens	P02533	Y2H Prey Pooling	32296183
Intra	KRT79	Q5XKE5	KRT14	Homo sapiens	P02533	Y2H Array	32296183
Intra	KRT79	Q5XKE5	KRT15	Homo sapiens	P19012	Validated Y2H	25416956
Intra	KRT79	Q5XKE5	KRT15	Homo sapiens	P19012	Y2H Prey Pooling	32296183
Intra	KRT79	Q5XKE5	KRT15	Homo sapiens	P19012	Y2H Array	32296183
Intra	KRT79	Q5XKE5	KRT15	Homo sapiens	P19012	Y2H Prey Pooling	25416956
Intra	KRT79	Q5XKE5	USHBP1	Homo sapiens	Q8N6Y0	Y2H Array	25416956
Intra	KRT79	Q5XKE5	KRT19	Homo sapiens	P08727	Y2H Array	32296183
Intra	KRT79	Q5XKE5	KRT19	Homo sapiens	P08727	Y2H Prey Pooling	32296183
Intra	KRT79	Q5XKE5	EVI5L	Homo sapiens	Q96CN4	Y2H Prey Pooling	32296183
Intra	KRT79	Q5XKE5	EVI5L	Homo sapiens	Q96CN4	Y2H Array	32296183
Intra	KRT79	Q5XKE5	KRT31	Homo sapiens	Q15323	Y2H Prey Pooling	32296183
Intra	KRT79	Q5XKE5	KRT31	Homo sapiens	Q15323	Y2H Array	32296183
Intra	KRT79	Q5XKE5	KRT31	Homo sapiens	Q15323	Validated Y2H	25416956
Intra	KRT79	Q5XKE5	KRT31	Homo sapiens	Q15323	Y2H Prey Pooling	25416956

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS07466	KRT79 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	KRT79	VGNC	VGNC:74150
Rattus norvegicus	KRT79	RGD	RGD:1583372
Felis catus	KRT79	VGNC	VGNC:63173
Bos taurus	KRT79	VGNC	VGNC:30741
Mus musculus	KRT79	MGD	MGI:2385030
Canis familiaris	KRT79	VGNC	VGNC:42533

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