2. Gene
  3. FAM174A - family with sequence similarity 174 member A Gene

FAM174A - family with sequence similarity 174 member A Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as NS5ATP6; TMEM157; UNQ1912; HGS_RE408

Gene ID: 345757 | Gene type: protein coding

About FAM174A

This gene has 3 transcripts (splice variants) and 108 orthologues. Ubiquitous expression in testis (RPKM 14.8), adrenal (RPKM 11.0) and 25 other tissues.

Summary

Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

FAM174A Products(1)

mRNA Protein Name
NM_198507.3 NP_940909.1 membrane protein FAM174A precursor
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

FAM174A Protein Structure

DUF1180

DUF1180: Protein of unknown function (DUF1180) (4 - 190)

  • 0
  • 100
  • 190 a.a.
Protein Preferred Names Protein Names

membrane protein FAM174A

HCV NS5A-transactivated protein 6

FAM174A Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
FAM174A Q8TBP5 DEFB127 Homo sapiens Q9H1M4
Validated Y2H
32296183
Intra
FAM174A Q8TBP5 SERP1 Homo sapiens Q9Y6X1
Validated Y2H
32296183
Intra
FAM174A Q8TBP5 TMEM239 Homo sapiens Q8WW34-2
Validated Y2H
32296183
Intra
FAM174A Q8TBP5 GIMAP1 Homo sapiens Q8WWP7
Validated Y2H
32296183
Intra
FAM174A Q8TBP5 C4orf3 Homo sapiens Q8WVX3-2
Validated Y2H
32296183
Intra
FAM174A Q8TBP5 TMEM203 Homo sapiens Q969S6
Validated Y2H
32296183
Intra
FAM174A Q8TBP5 TMEM243 Homo sapiens Q9BU79
Validated Y2H
32296183
Intra
FAM174A Q8TBP5 TREX1 Homo sapiens Q9NSU2-1
Validated Y2H
32296183
Intra
FAM174A Q8TBP5 CMTM7 Homo sapiens Q96FZ5
Validated Y2H
32296183
Intra
FAM174A Q8TBP5 TMEM222 Homo sapiens Q9H0R3
Validated Y2H
32296183
Intra
FAM174A Q8TBP5 PLLP Homo sapiens Q9Y342
Validated Y2H
32296183
Intra
FAM174A Q8TBP5 GIMAP5 Homo sapiens Q96F15
Validated Y2H
32296183
Intra
FAM174A Q8TBP5 ERG28 Homo sapiens Q9UKR5
Y2H Prey Pooling
32296183
Intra
FAM174A Q8TBP5 ERG28 Homo sapiens Q9UKR5
Validated Y2H
32296183
Intra
FAM174A Q8TBP5 STX8 Homo sapiens Q9UNK0
Validated Y2H
32296183
Intra
FAM174A Q8TBP5 SMCO4 Homo sapiens Q9NRQ5
Validated Y2H
32296183
Intra
FAM174A Q8TBP5 SLC30A2 Homo sapiens Q9BRI3
Validated Y2H
32296183
Intra
FAM174A Q8TBP5 SEC22A Homo sapiens Q96IW7
Validated Y2H
32296183
Intra
FAM174A Q8TBP5 CCDC167 Homo sapiens Q9P0B6
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04697 FAM174A Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus FAM174A RGD RGD:1309973
Felis catus FAM174A VGNC VGNC:62084
Canis familiaris FAM174A VGNC VGNC:40627
Bos taurus FAM174A VGNC VGNC:28761
Mus musculus FAM174A MGD MGI:1914948
Macaca mulatta FAM174A VGNC VGNC:110467