2. Gene
  3. SERP1 - stress associated endoplasmic reticulum protein 1 Gene

SERP1 - stress associated endoplasmic reticulum protein 1 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as RAMP4

Gene ID: 27230 | Gene type: protein coding

About SERP1

Cytogenetic location: 3q25.1 Genomic coordinates (GRCh38): 3:150,541,998-150,546,496 (from NCBI)

This gene has 8 transcripts (splice variants), 191 orthologues and 1 paralogue. Ubiquitous expression in thyroid (RPKM 68.2), prostate (RPKM 46.3) and 25 other tissues.

Summary

Predicted to be involved in endoplasmic reticulum unfolded protein response and protein glycosylation. Predicted to act upstream of or within several processes, including multicellular organism aging; positive regulation of organ growth; and positive regulation of peptide hormone secretion. Located in cytoplasmic microtubule. [provided by Alliance of Genome Resources, Apr 2022]

SERP1 Products(1)

mRNA Protein Name
NM_014445.4 NP_055260.1 stress-associated endoplasmic reticulum protein 1
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
Cellular Component GO Annotation Evidence Reference Source
located in cytoplasmic microtubule IDA
IDA: Inferred from direct assay
23264731 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SERP1 Protein Structure

RAMP4

RAMP4: Ribosome associated membrane protein RAMP4 (1 - 64)

  • 0
  • 66 a.a.
Protein Preferred Names Protein Names

stress-associated endoplasmic reticulum protein 1

ribosome associated membrane protein 4

SERP1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra SERP1 Q9Y6X1 JAGN1 Homo sapiens Q8N5M9
Y2H Prey Pooling
32296183
Intra SERP1 Q9Y6X1 JAGN1 Homo sapiens Q8N5M9
Y2H Array
32296183
Intra SERP1 Q9Y6X1 BSCL2 Homo sapiens J3KQ12
Y2H Array
32296183
Intra SERP1 Q9Y6X1 BSCL2 Homo sapiens J3KQ12
Y2H Prey Pooling
32296183
Intra SERP1 Q9Y6X1 GPX8 Homo sapiens Q8TED1
Y2H Prey Pooling
32296183
Intra SERP1 Q9Y6X1 GPX8 Homo sapiens Q8TED1
Y2H Array
32296183
Intra SERP1 Q9Y6X1 STX2 Homo sapiens P32856-2
Y2H Prey Pooling
32296183
Intra SERP1 Q9Y6X1 STX2 Homo sapiens P32856-2
Y2H Array
32296183
Intra SERP1 Q9Y6X1 CD74 Homo sapiens P04233-2
Y2H Prey Pooling
32296183
Intra SERP1 Q9Y6X1 CD74 Homo sapiens P04233-2
Y2H Array
32296183
Intra SERP1 Q9Y6X1 TNFRSF9 Homo sapiens Q07011
Y2H Array
32296183
Intra SERP1 Q9Y6X1 TNFRSF9 Homo sapiens Q07011
Y2H Prey Pooling
32296183
Intra SERP1 Q9Y6X1 TLCD4 Homo sapiens Q96MV1
Y2H Prey Pooling
32296183
Intra SERP1 Q9Y6X1 TLCD4 Homo sapiens Q96MV1
Y2H Array
32296183
Intra SERP1 Q9Y6X1 AQP6 Homo sapiens Q13520
Y2H Array
32296183
Intra SERP1 Q9Y6X1 AQP6 Homo sapiens Q13520
Y2H Prey Pooling
32296183
Intra SERP1 Q9Y6X1 CRB3 Homo sapiens Q9BUF7-2
Y2H Prey Pooling
32296183
Intra SERP1 Q9Y6X1 CRB3 Homo sapiens Q9BUF7-2
Y2H Array
32296183
Intra SERP1 Q9Y6X1 KIR3DL3 Homo sapiens Q8N743
Y2H Prey Pooling
32296183
Intra SERP1 Q9Y6X1 KIR3DL3 Homo sapiens Q8N743
Y2H Array
32296183
Intra SERP1 Q9Y6X1 SSMEM1 Homo sapiens Q8WWF3
Y2H Prey Pooling
32296183
Intra SERP1 Q9Y6X1 SSMEM1 Homo sapiens Q8WWF3
Y2H Array
32296183
Intra SERP1 Q9Y6X1 SLC35C2 Homo sapiens Q9NQQ7-3
Y2H Prey Pooling
32296183
Intra SERP1 Q9Y6X1 SLC35C2 Homo sapiens Q9NQQ7-3
Y2H Array
32296183
Intra SERP1 Q9Y6X1 IL3RA Homo sapiens P26951
Y2H Array
32296183
Intra SERP1 Q9Y6X1 IL3RA Homo sapiens P26951
Y2H Prey Pooling
32296183
Intra SERP1 Q9Y6X1 HSD17B13 Homo sapiens Q7Z5P4
Y2H Prey Pooling
32296183
Intra SERP1 Q9Y6X1 HSD17B13 Homo sapiens Q7Z5P4
Y2H Array
32296183
Intra SERP1 Q9Y6X1 PLPPR1 Homo sapiens Q8TBJ4
Y2H Array
32296183
Intra SERP1 Q9Y6X1 PLPPR1 Homo sapiens Q8TBJ4
Y2H Prey Pooling
32296183
Intra SERP1 Q9Y6X1 SLC10A6 Homo sapiens Q3KNW5
Y2H Array
32296183
Intra SERP1 Q9Y6X1 SLC10A6 Homo sapiens Q3KNW5
Y2H Prey Pooling
32296183
Intra SERP1 Q9Y6X1 TMEM52B Homo sapiens Q4KMG9
Y2H Array
32296183
Intra SERP1 Q9Y6X1 TMEM52B Homo sapiens Q4KMG9
Y2H Prey Pooling
32296183
Intra SERP1 Q9Y6X1 FAM209A Homo sapiens Q5JX71
Y2H Prey Pooling
32296183
Intra SERP1 Q9Y6X1 FAM209A Homo sapiens Q5JX71
Y2H Array
32296183
Intra SERP1 Q9Y6X1 FAM174A Homo sapiens Q8TBP5
Y2H Prey Pooling
32296183
Intra SERP1 Q9Y6X1 FAM174A Homo sapiens Q8TBP5
Y2H Array
32296183
Intra SERP1 Q9Y6X1 FAM210B Homo sapiens Q96KR6
Y2H Array
32296183
Intra SERP1 Q9Y6X1 FAM210B Homo sapiens Q96KR6
Y2H Prey Pooling
32296183
Intra SERP1 Q9Y6X1 AQP8 Homo sapiens O94778
Y2H Prey Pooling
32296183
Intra SERP1 Q9Y6X1 AQP8 Homo sapiens O94778
Y2H Array
32296183
Intra SERP1 Q9Y6X1 APH1A Homo sapiens Q96BI3
Y2H Prey Pooling
32296183
Intra SERP1 Q9Y6X1 APH1A Homo sapiens Q96BI3
Y2H Array
32296183
Intra SERP1 Q9Y6X1 LHFPL5 Homo sapiens Q8TAF8
Y2H Prey Pooling
32296183
Intra SERP1 Q9Y6X1 LHFPL5 Homo sapiens Q8TAF8
Y2H Array
32296183
Intra SERP1 Q9Y6X1 ALG3 Homo sapiens Q92685
Y2H Array
32296183
Intra SERP1 Q9Y6X1 ALG3 Homo sapiens Q92685
Y2H Prey Pooling
32296183
Intra SERP1 Q9Y6X1 SEC11C Homo sapiens Q9BY50
Y2H Array
32296183
Intra SERP1 Q9Y6X1 SEC11C Homo sapiens Q9BY50
Y2H Prey Pooling
32296183
Intra SERP1 Q9Y6X1 GPR37L1 Homo sapiens O60883
Y2H Array
32296183
Intra SERP1 Q9Y6X1 GPR37L1 Homo sapiens O60883
Y2H Prey Pooling
32296183
Intra SERP1 Q9Y6X1 MFSD14B Homo sapiens Q5SR56
Y2H Prey Pooling
32296183
Intra SERP1 Q9Y6X1 MFSD14B Homo sapiens Q5SR56
Y2H Array
32296183
Intra SERP1 Q9Y6X1 GJB3 Homo sapiens O75712
Y2H Array
32296183
Intra SERP1 Q9Y6X1 GJB3 Homo sapiens O75712
Y2H Prey Pooling
32296183
Intra SERP1 Q9Y6X1 GJB5 Homo sapiens O95377
Y2H Prey Pooling
32296183
Intra SERP1 Q9Y6X1 GJB5 Homo sapiens O95377
Y2H Array
32296183
Intra SERP1 Q9Y6X1 EBP Homo sapiens Q15125
Y2H Prey Pooling
32296183
Intra SERP1 Q9Y6X1 EBP Homo sapiens Q15125
Y2H Array
32296183
Intra SERP1 Q9Y6X1 SAR1A Homo sapiens Q9NR31
Y2H Array
32296183
Intra SERP1 Q9Y6X1 SAR1A Homo sapiens Q9NR31
Y2H Prey Pooling
32296183
Intra SERP1 Q9Y6X1 MTIF3 Homo sapiens Q9H2K0
Y2H Prey Pooling
32296183
Intra SERP1 Q9Y6X1 MTIF3 Homo sapiens Q9H2K0
Y2H Array
32296183
Intra SERP1 Q9Y6X1 GKN1 Homo sapiens Q9NS71
Y2H Prey Pooling
32296183
Intra SERP1 Q9Y6X1 GKN1 Homo sapiens Q9NS71
Y2H Array
32296183
Intra SERP1 Q9Y6X1 FRMD3 Homo sapiens A2A2Y4
Y2H Prey Pooling
32296183
Intra SERP1 Q9Y6X1 FRMD3 Homo sapiens A2A2Y4
Y2H Array
32296183
Intra SERP1 Q9Y6X1 KCNF1 Homo sapiens Q9H3M0
Y2H Prey Pooling
32296183
Intra SERP1 Q9Y6X1 KCNF1 Homo sapiens Q9H3M0
Y2H Array
32296183
Intra SERP1 Q9Y6X1 BIK Homo sapiens Q13323
Y2H Prey Pooling
32296183
Intra SERP1 Q9Y6X1 BIK Homo sapiens Q13323
Y2H Array
32296183
Intra SERP1 Q9Y6X1 STX1A Homo sapiens Q16623
Y2H Prey Pooling
32296183
Intra SERP1 Q9Y6X1 STX1A Homo sapiens Q16623
Y2H Array
32296183
Intra SERP1 Q9Y6X1 STX4 Homo sapiens Q12846
Y2H Prey Pooling
32296183
Intra SERP1 Q9Y6X1 STX4 Homo sapiens Q12846
Y2H Array
32296183
Intra SERP1 Q9Y6X1 REEP4 Homo sapiens Q9H6H4
Y2H Array
32296183
Intra SERP1 Q9Y6X1 REEP4 Homo sapiens Q9H6H4
Y2H Prey Pooling
32296183
Intra SERP1 Q9Y6X1 CD79A Homo sapiens P11912
Y2H Prey Pooling
32296183
Intra SERP1 Q9Y6X1 CD79A Homo sapiens P11912
Y2H Array
32296183
Intra SERP1 Q9Y6X1 CYBRD1 Homo sapiens Q53TN4
Y2H Prey Pooling
32296183
Intra SERP1 Q9Y6X1 CYBRD1 Homo sapiens Q53TN4
Y2H Array
32296183
Intra SERP1 Q9Y6X1 TMEM14B Homo sapiens Q9NUH8
Y2H Array
32296183
Intra SERP1 Q9Y6X1 TMEM14B Homo sapiens Q9NUH8
Y2H Prey Pooling
32296183
Intra SERP1 Q9Y6X1 TMEM79 Homo sapiens Q9BSE2
Y2H Prey Pooling
25416956
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Arachnoiditis

Spinal Arachnoiditis

Adhesive Arachnoiditis

Chronic Arachnoiditis

Familial Spinal Arachnoiditis

Arachnitis

Arachnoid Inflammation
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS12694 SERP1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS12727 SERPING1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus SERP1 VGNC VGNC:34464
Felis catus SERP1 VGNC VGNC:102840
Macaca mulatta SERP1 VGNC VGNC:77175
Rattus norvegicus SERP1 RGD RGD:620790
Mus musculus SERP1 MGD MGI:92638