2. Gene
  3. ING4 - inhibitor of growth family member 4 Gene

ING4 - inhibitor of growth family member 4 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as my036; p29ING4

Gene ID: 51147 | Gene type: protein coding

About ING4

Cytogenetic location: 12p13.31 Genomic coordinates (GRCh38): 12:6,650,301-6,663,119 (from NCBI)

This gene has 18 transcripts (splice variants), 222 orthologues and 4 paralogues. Ubiquitous expression in thyroid (RPKM 15.7), endometrium (RPKM 14.9) and 25 other tissues.

Summary

This gene encodes a tumor suppressor protein that contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This protein can bind TP53 and EP300/p300, a component of the histone acetyl transferase complex, suggesting its involvement in the TP53-dependent regulatory pathway. Multiple alternatively spliced transcript variants have been observed that encode distinct proteins. [provided by RefSeq, Jul 2008]

ING4 Products(6)

mRNA Protein Name
NM_001127582.2 NP_001121054.1 inhibitor of growth protein 4 isoform 9
NM_001127583.2 NP_001121055.1 inhibitor of growth protein 4 isoform 3
NM_001127584.2 NP_001121056.1 inhibitor of growth protein 4 isoform 4
NM_001127585.2 NP_001121057.1 inhibitor of growth protein 4 isoform 5
NM_001127586.2 NP_001121058.1 inhibitor of growth protein 4 isoform 6
NM_016162.4 NP_057246.2 inhibitor of growth protein 4 isoform 1

ING4 Protein Structure

ING

ING: Inhibitor of growth proteins N-terminal histone-binding (5 - 107)

PHD

PHD: PHD-finger (198 - 244)

  • 0
  • 100
  • 200
  • 249 a.a.
Protein Preferred Names Protein Names

inhibitor of growth protein 4

brain my036 protein

Recombinant ING4 Proteins

Cat. No. Product Name Accession Purity
HY-P74798 ING4 Protein, Human (His) Q9UNL4-1 (M1-K249) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06810 ING4 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus ING4 VGNC VGNC:30197
Mus musculus ING4 MGD MGI:107307
Macaca mulatta ING4 VGNC VGNC:73628
Felis catus ING4 VGNC VGNC:62923
Canis familiaris ING4 VGNC VGNC:103684
Rattus norvegicus ING4 RGD RGD:1309407
Others ING4 NCBI