2. Gene
  3. HSD17B14 - hydroxysteroid 17-beta dehydrogenase 14 Gene

HSD17B14 - hydroxysteroid 17-beta dehydrogenase 14 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as DHRS10; SDR47C1; retSDR3

Gene ID: 51171 | Gene type: protein coding

About HSD17B14

Cytogenetic location: 19q13.33 Genomic coordinates (GRCh38): 19:48,813,018-48,836,491 (from NCBI)

This gene has 4 transcripts (splice variants), 159 orthologues and 25 paralogues. Broad expression in kidney (RPKM 32.8), ovary (RPKM 12.9) and 14 other tissues.

Summary

17-beta-hydroxysteroid dehydrogenases, such as HSD17B14, are primarily involved in metabolism of Steroids at the C17 position and also of other substrates, such as fatty acids, prostaglandins, and xenobiotics (Lukacik et al., 2007 [PubMed 17067289]).[supplied by OMIM, Jun 2009]

HSD17B14 Products(1)

mRNA Protein Name
NM_016246.3 NP_057330.2 17-beta-hydroxysteroid dehydrogenase 14

HSD17B14 Protein Structure

adh_short

adh_short: short chain dehydrogenase (10 - 170)

  • 0
  • 100
  • 200
  • 270 a.a.
Protein Preferred Names Protein Names

17-beta-hydroxysteroid dehydrogenase 14

17-beta-HSD 14

Recombinant HSD17B14 Proteins

Cat. No. Product Name Accession Purity
HY-P76975 HSD17B14 Protein, Human (HEK293, His) Q9BPX1/NP_057330.2 (M1-S270) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06394 HSD17B14 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus HSD17B14 RGD RGD:1588673
Mus musculus HSD17B14 MGD MGI:1913315
Bos taurus HSD17B14 VGNC VGNC:29972
Felis catus HSD17B14 VGNC VGNC:97458
Canis familiaris HSD17B14 VGNC VGNC:41804
Others HSD17B14 NCBI