ZCCHC17 - zinc finger CCHC-type containing 17 Gene

Homo sapiens

Also known as PS1D; pNO40; HSPC251

Gene ID: 51538 | Gene type: protein coding

About ZCCHC17

Cytogenetic location: 1p35.2 Genomic coordinates (GRCh38): 1:31,297,032-31,364,936 (from NCBI)

This gene has 9 transcripts (splice variants) and 205 orthologues. Ubiquitous expression in heart (RPKM 23.1), brain (RPKM 18.8) and 24 other tissues.

Summary

Enables identical protein binding activity. Predicted to be involved in RNA stabilization. Predicted to be located in nucleolus. Predicted to be part of cytosolic large ribosomal subunit. [provided by Alliance of Genome Resources, Apr 2022]

ZCCHC17 Products(10)

mRNA	Protein	Name
NM_001282566.2	NP_001269495.1	zinc finger CCHC domain-containing protein 17 isoform a
NM_001282567.2	NP_001269496.1	zinc finger CCHC domain-containing protein 17 isoform b
NM_001282568.2	NP_001269497.1	zinc finger CCHC domain-containing protein 17 isoform c
NM_001282569.2	NP_001269498.1	zinc finger CCHC domain-containing protein 17 isoform d
NM_001282570.2	NP_001269499.1	zinc finger CCHC domain-containing protein 17 isoform e
NM_001282571.2	NP_001269500.1	zinc finger CCHC domain-containing protein 17 isoform f
NM_001282572.2	NP_001269501.1	zinc finger CCHC domain-containing protein 17 isoform g
NM_001282573.2	NP_001269502.1	zinc finger CCHC domain-containing protein 17 isoform h
NM_001282574.2	NP_001269503.1	zinc finger CCHC domain-containing protein 17 isoform i
NM_016505.4	NP_057589.2	zinc finger CCHC domain-containing protein 17 isoform c

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables identical protein binding	IPI IPI: Inferred from physical interaction	32296183	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	16189514	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ZCCHC17 Protein Structure

0
100
200
241 a.a.

Protein Preferred Names

Protein Names

zinc finger CCHC domain-containing protein 17

nucleolar protein of 40 kDa

nucleolar protein 40

ZCCHC17 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	ZCCHC17	Q9NP64	RNF4	Homo sapiens	P78317	Y2H Prey Pooling	32296183
Intra	ZCCHC17	Q9NP64	RNF4	Homo sapiens	P78317	Y2H Array	32296183
Intra	ZCCHC17	Q9NP64	q9y649_human	Homo sapiens	Q9Y649	Y2H Array	32814053
Intra	ZCCHC17	Q9NP64	q9y649_human	Homo sapiens	Q9Y649	Y2H Pooling	32814053
Intra	ZCCHC17	Q9NP64	q9y649_human	Homo sapiens	Q9Y649	Validated Y2H	32814053
Intra	ZCCHC17	Q9NP64	FGFR3	Homo sapiens	P22607	Y2H Pooling	32814053
Intra	ZCCHC17	Q9NP64	FGFR3	Homo sapiens	P22607	Validated Y2H	32814053
Intra	ZCCHC17	Q9NP64	FGFR3	Homo sapiens	P22607	Y2H Array	32814053
Intra	ZCCHC17	Q9NP64	GSN	Homo sapiens	P06396	Validated Y2H	32814053
Intra	ZCCHC17	Q9NP64	GSN	Homo sapiens	P06396	Y2H Array	32814053
Intra	ZCCHC17	Q9NP64	GSN	Homo sapiens	P06396	Y2H Pooling	32814053
Intra	ZCCHC17	Q9NP64	ZNF16	Homo sapiens	P17020	Y2H Array	32296183
Intra	ZCCHC17	Q9NP64	ZNF16	Homo sapiens	P17020	Y2H Prey Pooling	32296183
Intra	ZCCHC17	Q9NP64	SDCBP	Homo sapiens	O00560	Y2H Prey Pooling	32296183
Intra	ZCCHC17	Q9NP64	SDCBP	Homo sapiens	O00560	Y2H Array	32296183
Intra	ZCCHC17	Q9NP64	SDCBP	Homo sapiens	O00560	Y2H Prey Pooling	25416956
Intra	ZCCHC17	Q9NP64	SDCBP2	Homo sapiens	Q9H190	Y2H Prey Pooling	32296183
Intra	ZCCHC17	Q9NP64	SDCBP2	Homo sapiens	Q9H190	Y2H Array	25416956
Intra	ZCCHC17	Q9NP64	SDCBP2	Homo sapiens	Q9H190	Y2H Array	32296183
Intra	ZCCHC17	Q9NP64	SDCBP2	Homo sapiens	Q9H190	Y2H	21516116
Intra	ZCCHC17	Q9NP64	JMJD6	Homo sapiens	Q6NYC1	Anti Tag CoIP	23455924
Intra	ZCCHC17	Q9NP64	JMJD6	Homo sapiens	Q6NYC1	Anti Tag CoIP	33961781

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS16002	ZCCHC17 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	ZCCHC17	VGNC	VGNC:79840
Mus musculus	ZCCHC17	MGD	MGI:1919955
Felis catus	ZCCHC17	VGNC	VGNC:80409
Rattus norvegicus	ZCCHC17	RGD	RGD:1565267

Name
Email *

	Sorry, but the email address you supplied was invalid.