DUSP23 - dual specificity phosphatase 23 Gene

Homo sapiens

Also known as VHZ; LDP3; MOSP; LDP-3; DUSP25

Gene ID: 54935 | Gene type: protein coding

About DUSP23

Cytogenetic location: 1q23.2 Genomic coordinates (GRCh38): 1:159,780,962-159,782,543 (from NCBI)

This gene has 3 transcripts (splice variants) and 181 orthologues. Ubiquitous expression in kidney (RPKM 18.6), liver (RPKM 13.3) and 25 other tissues.

Summary

Enables protein tyrosine/serine/threonine Phosphatase activity. Involved in dephosphorylation. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

DUSP23 Products(3)

mRNA	Protein	Name
NM_001319658.2	NP_001306587.1	dual specificity protein phosphatase 23
NM_001319659.2	NP_001306588.1	dual specificity protein phosphatase 23
NM_017823.5	NP_060293.2	dual specificity protein phosphatase 23

DUSP23 Protein Structure

DSPc

0
100
150 a.a.

Protein Preferred Names

Protein Names

dual specificity protein phosphatase 23

VH1-like member Z

DUSP23 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	DUSP23	Q9BVJ7	BANF2	Homo sapiens	Q9H503-2	Y2H Prey Pooling	32296183
Intra	DUSP23	Q9BVJ7	BANF2	Homo sapiens	Q9H503-2	Validated Y2H	32296183
Intra	DUSP23	Q9BVJ7	BANF2	Homo sapiens	Q9H503-2	Y2H Array	32296183
Intra	DUSP23	Q9BVJ7	TCF4	Homo sapiens	P15884-3	Y2H Array	32296183
Intra	DUSP23	Q9BVJ7	TCF4	Homo sapiens	P15884-3	Y2H Prey Pooling	32296183
Intra	DUSP23	Q9BVJ7	MRNIP	Homo sapiens	Q6NTE8	Y2H Array	32296183
Intra	DUSP23	Q9BVJ7	MRNIP	Homo sapiens	Q6NTE8	Y2H Prey Pooling	32296183
Intra	DUSP23	Q9BVJ7	EXOSC8	Homo sapiens	Q96B26	Y2H Array	32296183
Intra	DUSP23	Q9BVJ7	EXOSC8	Homo sapiens	Q96B26	Validated Y2H	25910212
Intra	DUSP23	Q9BVJ7	EXOSC8	Homo sapiens	Q96B26	Y2H Bait-Prey Pool	25910212
Intra	DUSP23	Q9BVJ7	EXOSC8	Homo sapiens	Q96B26	Y2H Array	25910212
Intra	DUSP23	Q9BVJ7	EXOSC8	Homo sapiens	Q96B26	Y2H Prey Pooling	32296183
Intra	DUSP23	Q9BVJ7	PSMB8	Homo sapiens	P28062-2	Y2H Array	32296183
Intra	DUSP23	Q9BVJ7	PSMB8	Homo sapiens	P28062-2	Y2H Prey Pooling	32296183
Intra	DUSP23	Q9BVJ7	ASB6	Homo sapiens	Q9NWX5	Y2H Prey Pooling	32296183
Intra	DUSP23	Q9BVJ7	ASB6	Homo sapiens	Q9NWX5	Validated Y2H	32296183
Intra	DUSP23	Q9BVJ7	ASB6	Homo sapiens	Q9NWX5	Y2H Array	32296183
Intra	DUSP23	Q9BVJ7	UBA3	Homo sapiens	Q8TBC4	Y2H Array	32296183
Intra	DUSP23	Q9BVJ7	UBA3	Homo sapiens	Q8TBC4	Y2H Prey Pooling	32296183
Intra	DUSP23	Q9BVJ7	NIF3L1	Homo sapiens	Q9GZT8	Validated Y2H	25416956
Intra	DUSP23	Q9BVJ7	NIF3L1	Homo sapiens	Q9GZT8	Y2H Prey Pooling	25416956
Intra	DUSP23	Q9BVJ7	PSME2	Homo sapiens	Q9UL46	Y2H Prey Pooling	32296183
Intra	DUSP23	Q9BVJ7	PSME2	Homo sapiens	Q9UL46	Validated Y2H	32296183
Intra	DUSP23	Q9BVJ7	PSME2	Homo sapiens	Q9UL46	Y2H Array	32296183
Intra	DUSP23	Q9BVJ7	DDIT4L	Homo sapiens	Q96D03	Y2H Prey Pooling	32296183
Intra	DUSP23	Q9BVJ7	DDIT4L	Homo sapiens	Q96D03	Y2H Array	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases

Alias

West Nile Fever

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS04062	DUSP23 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	DUSP23	VGNC	VGNC:71880
Mus musculus	DUSP23	MGD	MGI:1915690
Felis catus	DUSP23	VGNC	VGNC:107869
Rattus norvegicus	DUSP23	RGD	RGD:1309202
Bos taurus	DUSP23	VGNC	VGNC:28257

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