2. Gene
  3. ARL8B - ADP ribosylation factor like GTPase 8B Gene

ARL8B - ADP ribosylation factor like GTPase 8B Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as Gie1; ARL10C

Gene ID: 55207 | Gene type: protein coding

About ARL8B

Cytogenetic location: 3p26.1 Genomic coordinates (GRCh38): 3:5,122,292-5,180,911 (from NCBI)

This gene has 7 transcripts (splice variants), 270 orthologues and 30 paralogues. Ubiquitous expression in brain (RPKM 48.8), thyroid (RPKM 43.1) and 25 other tissues.

Summary

Enables guanyl ribonucleotide binding activity and tubulin binding activity. Involved in several processes, including calcium ion regulated lysosome exocytosis; lysosomal transport; and vesicle fusion. Located in cytolytic granule membrane; midbody; and spindle midzone. Colocalizes with lysosomal membrane. [provided by Alliance of Genome Resources, Apr 2022]

ARL8B Products(1)

mRNA Protein Name
NM_018184.3 NP_060654.1 ADP-ribosylation factor-like protein 8B

ARL8B Protein Structure

Arf

Arf: ADP-ribosylation factor family (11 - 179)

  • 0
  • 100
  • 186 a.a.
Protein Preferred Names Protein Names

ADP-ribosylation factor-like protein 8B

ADP-ribosylation factor-like 10C

Related Diseases

Diseases Alias
Spondylometaphyseal Dysplasia, Sedaghatian Type

SMDS

Sedaghatian Chondrodysplasia

Spondylometaphyseal Dysplasia Sedaghatian Type

Congenital Lethal Metaphyseal Chondrodysplasia

Metaphyseal Chondrodysplasia, Congenital Lethal

Lethal Metaphyseal Dysplasia
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00999 ARL8B Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta ARL8B VGNC VGNC:84238
Rattus norvegicus ARL8B RGD RGD:1562830
Mus musculus ARL8B MGD MGI:1914416
Canis familiaris ARL8B VGNC VGNC:38122
Felis catus ARL8B VGNC VGNC:59930
Bos taurus ARL8B VGNC VGNC:26154