SNW1 - SNW domain containing 1 Gene

Homo sapiens

Also known as Bx42; SKIP; FUN20; Prp45; SKIIP; SKIP1; PRPF45; NCOA-62

Gene ID: 22938 | Gene type: protein coding

About SNW1

Cytogenetic location: 14q24.3 Genomic coordinates (GRCh38): 14:77,717,599-77,761,156 (from NCBI)

This gene has 7 transcripts (splice variants) and 230 orthologues. Ubiquitous expression in bone marrow (RPKM 34.9), testis (RPKM 33.4) and 25 other tissues.

Summary

This gene, a member of the SNW gene family, encodes a coactivator that enhances transcription from some Pol II promoters. This coactivator can bind to the ligand-binding domain of the vitamin D receptor and to retinoid receptors to enhance vitamin D-, retinoic acid-, estrogen-, and glucocorticoid-mediated gene expression. It can also function as a splicing factor by interacting with poly(A)-binding protein 2 to directly control the expression of muscle-specific genes at the transcriptional level. Finally, the protein may be involved in oncogenesis since it interacts with a region of SKI oncoproteins that is required for transforming activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]

SNW1 Products(2)

mRNA	Protein	Name
NM_001318844.2	NP_001305773.1	SNW domain-containing protein 1 isoform 1
NM_012245.3	NP_036377.1	SNW domain-containing protein 1 isoform 2

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables Notch binding	IPI IPI: Inferred from physical interaction	10713164	GOA
enables SMAD binding	IDA IDA: Inferred from direct assay	11278756	GOA
enables enzyme binding	IPI IPI: Inferred from physical interaction	20007319	GOA
enables nuclear androgen receptor binding	IPI IPI: Inferred from physical interaction	23566155	GOA
enables nuclear receptor binding	IDA IDA: Inferred from direct assay	19934264	GOA
enables nuclear retinoic acid receptor binding	IDA IDA: Inferred from direct assay	11514567	GOA
enables nuclear vitamin D receptor binding	IDA IDA: Inferred from direct assay	12529369	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	9569025	GOA
enables transcription coactivator activity	IDA IDA: Inferred from direct assay	11514567	GOA
enables transcription corepressor activity	IDA IDA: Inferred from direct assay	14985122	GOA

Biological Process GO Annotation	Evidence	Reference	Source
involved in cellular response to retinoic acid	IDA IDA: Inferred from direct assay	19934264	GOA
involved in intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	IMP IMP: Inferred from mutant phenotype	21460037	GOA
involved in mRNA splicing, via spliceosome	IDA IDA: Inferred from direct assay	15194481	GOA
acts upstream of or within negative regulation of DNA-templated transcription	IDA IDA: Inferred from direct assay	15878163	GOA
involved in negative regulation of DNA-templated transcription	IDA IDA: Inferred from direct assay	10713164	GOA
involved in negative regulation of transcription by RNA polymerase II	IDA IDA: Inferred from direct assay	14985122	GOA
involved in positive regulation by host of viral transcription	IDA IDA: Inferred from direct assay	15905409	GOA
involved in positive regulation by host of viral transcription	IMP IMP: Inferred from mutant phenotype	19818711	GOA
involved in positive regulation of mRNA splicing, via spliceosome	IMP IMP: Inferred from mutant phenotype	12840015	GOA
involved in positive regulation of transcription by RNA polymerase II	IDA IDA: Inferred from direct assay	14985122	GOA
involved in positive regulation of transforming growth factor beta receptor signaling pathway	IDA IDA: Inferred from direct assay	11278756	GOA
involved in positive regulation of vitamin D receptor signaling pathway	IDA IDA: Inferred from direct assay	9632709	GOA
involved in regulation of retinoic acid receptor signaling pathway	IDA IDA: Inferred from direct assay	14985122	GOA
involved in regulation of vitamin D receptor signaling pathway	IDA IDA: Inferred from direct assay	14985122	GOA
involved in retinoic acid receptor signaling pathway	IDA IDA: Inferred from direct assay	19934264	GOA

Cellular Component GO Annotation	Evidence	Reference	Source
part of U2-type catalytic step 2 spliceosome	IDA IDA: Inferred from direct assay	28076346	GOA
part of catalytic step 2 spliceosome	IDA IDA: Inferred from direct assay	11991638	GOA
part of cyclin/CDK positive transcription elongation factor complex	IDA IDA: Inferred from direct assay	15905409	GOA
located in nuclear matrix	IDA IDA: Inferred from direct assay	12840015	GOA
located in nuclear speck	IDA IDA: Inferred from direct assay	23566155	GOA
located in nucleus	IDA IDA: Inferred from direct assay	9569025	GOA
part of spliceosomal complex	IDA IDA: Inferred from direct assay	15194481	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SNW1 Protein Structure

SKIP_SNW

0
100
200
300
400
500
536 a.a.

Protein Preferred Names

Protein Names

SNW domain-containing protein 1

SKI interacting protein

SNW1 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	SNW1	Q13573	NF2	Homo sapiens	P35240	Validated Y2H	32814053
Intra	SNW1	Q13573	NF2	Homo sapiens	P35240	Y2H Pooling	32814053
Intra	SNW1	Q13573	NF2	Homo sapiens	P35240	Y2H Array	32814053
Intra	SNW1	Q13573	KRT40	Homo sapiens	Q6A162	Validated Y2H	25416956
Intra	SNW1	Q13573	KRT40	Homo sapiens	Q6A162	Y2H Prey Pooling	25416956
Intra	SNW1	Q13573	SMAD2	Homo sapiens	Q15796	Pull Down	11278756
Intra	SNW1	Q13573	SMAD2	Homo sapiens	Q15796	Y2H	11278756
Intra	SNW1	Q13573	JPH3	Homo sapiens	Q8WXH2	Validated Y2H	32814053
Intra	SNW1	Q13573	JPH3	Homo sapiens	Q8WXH2	Y2H Pooling	32814053
Intra	SNW1	Q13573	JPH3	Homo sapiens	Q8WXH2	Y2H Array	32814053
Intra	SNW1	Q13573	HOOK2	Homo sapiens	Q96ED9-2	Y2H Prey Pooling	32296183
Intra	SNW1	Q13573	HOOK2	Homo sapiens	Q96ED9-2	Validated Y2H	32296183
Intra	SNW1	Q13573	HOOK2	Homo sapiens	Q96ED9-2	Y2H Array	32296183
Intra	SNW1	Q13573	KIF1B	Homo sapiens	O60333-2	Y2H Array	32814053
Intra	SNW1	Q13573	KIF1B	Homo sapiens	O60333-2	Validated Y2H	32814053
Intra	SNW1	Q13573	KIF1B	Homo sapiens	O60333-2	Y2H Pooling	32814053
Intra	SNW1	Q13573	DMWD	Homo sapiens	G5E9A7	Y2H Pooling	32814053
Intra	SNW1	Q13573	DMWD	Homo sapiens	G5E9A7	Validated Y2H	32814053
Intra	SNW1	Q13573	DMWD	Homo sapiens	G5E9A7	Y2H Array	32814053
Intra	SNW1	Q13573	TFIP11	Homo sapiens	Q9UBB9	Anti Tag CoIP	33961781
Intra	SNW1	Q13573	TFIP11	Homo sapiens	Q9UBB9	Y2H Array	32296183
Intra	SNW1	Q13573	TFIP11	Homo sapiens	Q9UBB9	Validated Y2H	32296183
Intra	SNW1	Q13573	TFIP11	Homo sapiens	Q9UBB9	Y2H Prey Pooling	32296183
Intra	SNW1	Q13573	TFIP11	Homo sapiens	Q9UBB9	Y2H Array	31515488
Intra	SNW1	Q13573	TFIP11	Homo sapiens	Q9UBB9	Y2H Prey Pooling	25416956
Intra	SNW1	Q13573	MTUS2	Homo sapiens	Q5JR59-3	Y2H Array	32296183
Intra	SNW1	Q13573	MTUS2	Homo sapiens	Q5JR59-3	Validated Y2H	32296183
Intra	SNW1	Q13573	MTUS2	Homo sapiens	Q5JR59-3	Y2H Prey Pooling	32296183
Intra	SNW1	Q13573	BICD2	Homo sapiens	Q8TD16-2	Y2H Prey Pooling	32296183
Intra	SNW1	Q13573	BICD2	Homo sapiens	Q8TD16-2	Validated Y2H	32296183
Intra	SNW1	Q13573	BICD2	Homo sapiens	Q8TD16-2	Y2H Array	32296183
Intra	SNW1	Q13573	CCDC125	Homo sapiens	Q86Z20	Validated Y2H	32296183
Intra	SNW1	Q13573	CCDC125	Homo sapiens	Q86Z20	Y2H Prey Pooling	32296183
Intra	SNW1	Q13573	CCDC125	Homo sapiens	Q86Z20	Y2H Array	32296183
Intra	SNW1	Q13573	PABPN1	Homo sapiens	Q86U42	Anti Bait CoIP	20467437
Intra	SNW1	Q13573	PABPN1	Homo sapiens	Q86U42	Confocal	11371506
Intra	SNW1	Q13573	CLSTN1	Homo sapiens	O94985-2	Y2H Pooling	32814053
Intra	SNW1	Q13573	CLSTN1	Homo sapiens	O94985-2	Validated Y2H	32814053
Intra	SNW1	Q13573	CLSTN1	Homo sapiens	O94985-2	Y2H Array	32814053
Intra	SNW1	Q13573	SIRT1	Homo sapiens	Q96EB6	Y2H	19934264
Intra	SNW1	Q13573	SIRT1	Homo sapiens	Q96EB6	Pull Down	19934264
Intra	SNW1	Q13573	SIRT1	Homo sapiens	Q96EB6	Anti Tag CoIP	19934264
Intra	SNW1	Q13573	HMBOX1	Homo sapiens	Q6NT76	Y2H Array	32296183
Intra	SNW1	Q13573	HMBOX1	Homo sapiens	Q6NT76	Y2H Prey Pooling	32296183
Intra	SNW1	Q13573	HMBOX1	Homo sapiens	Q6NT76	Validated Y2H	32296183
Intra	SNW1	Q13573	MISP	Homo sapiens	Q8IVT2	Validated Y2H	32296183
Intra	SNW1	Q13573	TCP11L1	Homo sapiens	Q9NUJ3	Validated Y2H	32296183
Intra	SNW1	Q13573	KANK2	Homo sapiens	Q63ZY3	Y2H Prey Pooling	32296183
Intra	SNW1	Q13573	KANK2	Homo sapiens	Q63ZY3	Validated Y2H	32296183
Intra	SNW1	Q13573	KANK2	Homo sapiens	Q63ZY3	Y2H Array	32296183
Intra	SNW1	Q13573	PPIL1	Homo sapiens	Q9Y3C6	Validated Y2H	32296183
Intra	SNW1	Q13573	PPIL1	Homo sapiens	Q9Y3C6	Anti Tag CoIP	33961781
Intra	SNW1	Q13573	PPIL1	Homo sapiens	Q9Y3C6	SPR	16595688
Intra	SNW1	Q13573	PPIL1	Homo sapiens	Q9Y3C6	Peptide Array	20368803
Intra	SNW1	Q13573	PPIL1	Homo sapiens	Q9Y3C6	Y2H Prey Pooling	25416956
Intra	SNW1	Q13573	TOR1AIP1	Homo sapiens	Q5JTV8	Y2H Array	32814053
Intra	SNW1	Q13573	TOR1AIP1	Homo sapiens	Q5JTV8	Validated Y2H	32814053
Intra	SNW1	Q13573	TOR1AIP1	Homo sapiens	Q5JTV8	Y2H Pooling	32814053
Intra	SNW1	Q13573	PPIA	Homo sapiens	P62937-2	Validated Y2H	32814053
Intra	SNW1	Q13573	PPIA	Homo sapiens	P62937-2	Y2H Array	32814053
Intra	SNW1	Q13573	PPIA	Homo sapiens	P62937-2	Y2H Pooling	32814053
Intra	SNW1	Q13573	q9y649_human	Homo sapiens	Q9Y649	Validated Y2H	32814053
Intra	SNW1	Q13573	q9y649_human	Homo sapiens	Q9Y649	Y2H Array	32814053
Intra	SNW1	Q13573	q9y649_human	Homo sapiens	Q9Y649	Y2H Pooling	32814053
Intra	SNW1	Q13573	PRKAR1B	Homo sapiens	P31321	Y2H Array	32296183
Intra	SNW1	Q13573	PRKAR1B	Homo sapiens	P31321	Y2H Prey Pooling	32296183
Intra	SNW1	Q13573	VDR	Homo sapiens	P11473	Pull Down	9632709
Intra	SNW1	Q13573	VDR	Homo sapiens	P11473	Y2H	9632709
Intra	SNW1	Q13573	XAB2	Homo sapiens	Q9HCS7	Anti Tag CoIP	33961781
Intra	SNW1	Q13573	XAB2	Homo sapiens	Q9HCS7	Y2H	22365833
Intra	SNW1	Q13573	XAB2	Homo sapiens	Q9HCS7	Anti Tag CoIP	22365833
Cross	SNW1	Q13573	Vdr	Mus musculus	P48281	Pull Down	12529369
Cross	SNW1	Q13573	Vdr	Mus musculus	P48281	Y2H	12529369
Intra	SNW1	Q13573	SMAD3	Homo sapiens	P84022	Y2H	11278756
Intra	SNW1	Q13573	SMAD3	Homo sapiens	P84022	Pull Down	11278756
Intra	SNW1	Q13573	FGFR3	Homo sapiens	P22607	Validated Y2H	32814053
Intra	SNW1	Q13573	FGFR3	Homo sapiens	P22607	Y2H Pooling	32814053
Intra	SNW1	Q13573	FGFR3	Homo sapiens	P22607	Y2H Array	32814053
Cross	SNW1	Q13573	Ncor1	Mus musculus	Q60974	Pull Down	14985122
Intra	SNW1	Q13573	HRAS	Homo sapiens	P01112	Validated Y2H	32814053
Intra	SNW1	Q13573	HRAS	Homo sapiens	P01112	Y2H Pooling	32814053
Intra	SNW1	Q13573	HRAS	Homo sapiens	P01112	Y2H Array	32814053
Intra	SNW1	Q13573	SPECC1L	Homo sapiens	Q69YQ0	Y2H Prey Pooling	32296183
Intra	SNW1	Q13573	SPECC1L	Homo sapiens	Q69YQ0	Validated Y2H	32296183
Intra	SNW1	Q13573	SPECC1L	Homo sapiens	Q69YQ0	Y2H Array	32296183
Intra	SNW1	Q13573	LMNA	Homo sapiens	P02545	Anti Bait CoIP	20467437
Intra	SNW1	Q13573	THRAP3	Homo sapiens	Q9Y2W1	Anti Bait CoIP	20467437
Intra	SNW1	Q13573	THRAP3	Homo sapiens	Q9Y2W1	Anti Tag CoIP	18794151
Intra	SNW1	Q13573	HSPB1	Homo sapiens	P04792	Anti Bait CoIP	20467437
Intra	SNW1	Q13573	HSPA5	Homo sapiens	P11021	Validated Y2H	32814053
Intra	SNW1	Q13573	HSPA5	Homo sapiens	P11021	Y2H Pooling	32814053
Intra	SNW1	Q13573	HSPA5	Homo sapiens	P11021	Pull Down	12840015
Intra	SNW1	Q13573	HSPA5	Homo sapiens	P11021	Anti Bait CoIP	20467437
Intra	SNW1	Q13573	HSPA5	Homo sapiens	P11021	Y2H Array	32814053
Intra	SNW1	Q13573	BYSL	Homo sapiens	Q13895	Validated Y2H	32296183
Intra	SNW1	Q13573	TRAF1	Homo sapiens	Q13077	Validated Y2H	25416956
Intra	SNW1	Q13573	YWHAG	Homo sapiens	P61981	Y2H Array	32814053
Intra	SNW1	Q13573	YWHAG	Homo sapiens	P61981	Y2H Pooling	32814053
Intra	SNW1	Q13573	YWHAG	Homo sapiens	P61981	Validated Y2H	32814053
Intra	SNW1	Q13573	EXOSC5	Homo sapiens	Q9NQT4	Validated Y2H	32296183
Intra	SNW1	Q13573	FOXN3	Homo sapiens	O00409	Anti Tag CoIP	16102918
Intra	SNW1	Q13573	FOXN3	Homo sapiens	O00409	Reverse RRS	16102918
Intra	SNW1	Q13573	ZNF830	Homo sapiens	Q96NB3	Anti Tag CoIP	33961781
Intra	SNW1	Q13573	ZNF830	Homo sapiens	Q96NB3	Anti Tag CoIP	22365833
Intra	SNW1	Q13573	RNF11	Homo sapiens	Q9Y3C5	Validated Y2H	32814053
Intra	SNW1	Q13573	RNF11	Homo sapiens	Q9Y3C5	Y2H Array	32814053
Intra	SNW1	Q13573	RNF11	Homo sapiens	Q9Y3C5	Y2H Pooling	32814053
Intra	SNW1	Q13573	NXF1	Homo sapiens	Q9UBU9	Validated Y2H	32296183
Intra	SNW1	Q13573	KAT5	Homo sapiens	Q92993	Y2H Pooling	32814053
Intra	SNW1	Q13573	KAT5	Homo sapiens	Q92993	Validated Y2H	32814053
Intra	SNW1	Q13573	KAT5	Homo sapiens	Q92993	Y2H Array	32814053
Intra	SNW1	Q13573	ARL8A	Homo sapiens	Q96BM9	Anti Tag CoIP	28325809
Intra	SNW1	Q13573	ARL8A	Homo sapiens	Q96BM9	Y2H	28325809
Intra	SNW1	Q13573	CYCS	Homo sapiens	P99999	Y2H Pooling	32814053
Intra	SNW1	Q13573	CYCS	Homo sapiens	P99999	Validated Y2H	32814053
Intra	SNW1	Q13573	CYCS	Homo sapiens	P99999	Y2H Array	32814053
Intra	SNW1	Q13573	RABEP1	Homo sapiens	Q15276	Y2H Array	32296183
Intra	SNW1	Q13573	RABEP1	Homo sapiens	Q15276	Y2H Prey Pooling	32296183
Intra	SNW1	Q13573	RABEP1	Homo sapiens	Q15276	Validated Y2H	32296183
Intra	SNW1	Q13573	HIP1	Homo sapiens	O00291	Validated Y2H	32814053
Intra	SNW1	Q13573	HIP1	Homo sapiens	O00291	Y2H Array	32814053
Intra	SNW1	Q13573	HIP1	Homo sapiens	O00291	Y2H Pooling	32814053
Intra	SNW1	Q13573	NEFL	Homo sapiens	P07196	Validated Y2H	32814053
Intra	SNW1	Q13573	NEFL	Homo sapiens	P07196	Y2H Pooling	32814053
Intra	SNW1	Q13573	NEFL	Homo sapiens	P07196	Y2H Array	32814053
Intra	SNW1	Q13573	SPRED1	Homo sapiens	Q7Z699	Y2H Array	32814053
Intra	SNW1	Q13573	SPRED1	Homo sapiens	Q7Z699	Validated Y2H	32814053
Intra	SNW1	Q13573	SPRED1	Homo sapiens	Q7Z699	Y2H Pooling	32814053
Intra	SNW1	Q13573	CWF19L2	Homo sapiens	Q2TBE0	Anti Tag CoIP	33961781
Intra	SNW1	Q13573	CWF19L2	Homo sapiens	Q2TBE0	Validated Y2H	32296183
Intra	SNW1	Q13573	SART1	Homo sapiens	O43290	Anti Bait CoIP	20467437
Intra	SNW1	Q13573	GOLGA2	Homo sapiens	Q08379	Y2H Array	25416956
Intra	SNW1	Q13573	GOLGA2	Homo sapiens	Q08379	Y2H Array	32296183
Intra	SNW1	Q13573	GOLGA2	Homo sapiens	Q08379	Y2H Prey Pooling	25416956
Intra	SNW1	Q13573	GOLGA2	Homo sapiens	Q08379	Y2H Prey Pooling	32296183
Intra	SNW1	Q13573	RBPJ	Homo sapiens	Q06330	Pull Down	10713164
Intra	SNW1	Q13573	NOTCH1	Homo sapiens	P46531	Y2H	10713164
Intra	SNW1	Q13573	FAM90A1	Homo sapiens	Q86YD7	Validated Y2H	32296183
Intra	SNW1	Q13573	PNN	Homo sapiens	Q9H307	Anti Bait CoIP	20467437
Intra	SNW1	Q13573	PNN	Homo sapiens	Q9H307	Anti Tag CoIP	18794151
Intra	SNW1	Q13573	HSF2BP	Homo sapiens	O75031	Y2H Array	32296183
Intra	SNW1	Q13573	HSF2BP	Homo sapiens	O75031	Y2H Prey Pooling	32296183
Intra	SNW1	Q13573	GRIPAP1	Homo sapiens	Q4V328	Validated Y2H	32296183
Intra	SNW1	Q13573	ARL8B	Homo sapiens	Q9NVJ2	Y2H	28325809
Intra	SNW1	Q13573	ARL8B	Homo sapiens	Q9NVJ2	Anti Tag CoIP	28325809
Intra	SNW1	Q13573	RINT1	Homo sapiens	Q6NUQ1	Y2H Array	31515488
Intra	SNW1	Q13573	RINT1	Homo sapiens	Q6NUQ1	Y2H Prey Pooling	25416956
Intra	SNW1	Q13573	RINT1	Homo sapiens	Q6NUQ1	Y2H Prey Pooling	32296183
Intra	SNW1	Q13573	RINT1	Homo sapiens	Q6NUQ1	Validated Y2H	32296183
Intra	SNW1	Q13573	RINT1	Homo sapiens	Q6NUQ1	Y2H Array	32296183
Intra	SNW1	Q13573	CEP70	Homo sapiens	Q8NHQ1	Validated Y2H	32296183
Intra	SNW1	Q13573	CEP70	Homo sapiens	Q8NHQ1	Y2H Array	32296183
Intra	SNW1	Q13573	CEP70	Homo sapiens	Q8NHQ1	Y2H Prey Pooling	32296183
Intra	SNW1	Q13573	MAGEA1	Homo sapiens	P43355	Y2H	15316101
Intra	SNW1	Q13573	MAGEA1	Homo sapiens	P43355	Anti Bait CoIP	15316101
Intra	SNW1	Q13573	LZTS2	Homo sapiens	Q9BRK4	Y2H Array	25416956
Intra	SNW1	Q13573	U2AF2	Homo sapiens	P26368	Pull Down	21460037
Intra	SNW1	Q13573	U2AF2	Homo sapiens	P26368	Anti Bait CoIP	20467437
Intra	SNW1	Q13573	TEX11	Homo sapiens	Q8IYF3	Validated Y2H	25416956
Intra	SNW1	Q13573	TEX11	Homo sapiens	Q8IYF3	Y2H Array	25416956
Intra	SNW1	Q13573	MTUS2	Homo sapiens	Q5JR59	Validated Y2H	25416956
Intra	SNW1	Q13573	GFAP	Homo sapiens	P14136	Validated Y2H	32814053
Intra	SNW1	Q13573	GFAP	Homo sapiens	P14136	Y2H Array	32814053
Intra	SNW1	Q13573	GFAP	Homo sapiens	P14136	Y2H Pooling	32814053
Intra	SNW1	Q13573	IKZF1	Homo sapiens	Q13422	Y2H Prey Pooling	25416956
Intra	SNW1	Q13573	MAGOHB	Homo sapiens	Q96A72	Validated Y2H	32296183
Intra	SNW1	Q13573	C1orf216	Homo sapiens	Q8TAB5	Validated Y2H	32296183
Intra	SNW1	Q13573	CEP55	Homo sapiens	Q53EZ4	Y2H Prey Pooling	25416956
Intra	SNW1	Q13573	CTNNBL1	Homo sapiens	Q8WYA6	Anti Tag CoIP	22365833
Intra	SNW1	Q13573	OPTN	Homo sapiens	Q96CV9	Y2H Pooling	32814053
Intra	SNW1	Q13573	OPTN	Homo sapiens	Q96CV9	Validated Y2H	32814053
Intra	SNW1	Q13573	OPTN	Homo sapiens	Q96CV9	Y2H Array	32814053
Intra	SNW1	Q13573	SNIP1	Homo sapiens	Q8TAD8	Anti Tag CoIP	22365833
Intra	SNW1	Q13573	SNIP1	Homo sapiens	Q8TAD8	Y2H	22365833
Intra	SNW1	Q13573	PRPH	Homo sapiens	P41219	Validated Y2H	32814053
Intra	SNW1	Q13573	PRPH	Homo sapiens	P41219	Y2H Array	32814053
Intra	SNW1	Q13573	PRPH	Homo sapiens	P41219	Y2H Pooling	32814053
Intra	SNW1	Q13573	PICK1	Homo sapiens	Q9NRD5	Validated Y2H	32296183
Intra	SNW1	Q13573	PICK1	Homo sapiens	Q9NRD5	Y2H Array	32296183
Intra	SNW1	Q13573	PICK1	Homo sapiens	Q9NRD5	Y2H Prey Pooling	32296183
Intra	SNW1	Q13573	CHRNA7	Homo sapiens	P36544	Validated Y2H	32814053
Intra	SNW1	Q13573	CHRNA7	Homo sapiens	P36544	Y2H Array	32814053
Intra	SNW1	Q13573	CHRNA7	Homo sapiens	P36544	Y2H Pooling	32814053
Intra	SNW1	Q13573	GAS2L2	Homo sapiens	Q8NHY3	Validated Y2H	32296183
Intra	SNW1	Q13573	NCOR2	Homo sapiens	Q9Y618	Anti Bait CoIP	20467437
Intra	SNW1	Q13573	NCOR2	Homo sapiens	Q9Y618	Y2H	10713164
Intra	SNW1	Q13573	IKBKG	Homo sapiens	Q9Y6K9	Validated Y2H	32296183
Intra	SNW1	Q13573	IKBKG	Homo sapiens	Q9Y6K9	Y2H Array	32296183
Intra	SNW1	Q13573	IKBKG	Homo sapiens	Q9Y6K9	Y2H Prey Pooling	32296183
Intra	SNW1	Q13573	SETDB1	Homo sapiens	Q15047-2	Validated Y2H	32814053
Intra	SNW1	Q13573	SETDB1	Homo sapiens	Q15047-2	Y2H Array	32814053
Intra	SNW1	Q13573	SETDB1	Homo sapiens	Q15047-2	Y2H Pooling	32814053
Intra	SNW1	Q13573	ODF2	Homo sapiens	Q5BJF6-2	Validated Y2H	32296183
Intra	SNW1	Q13573	MCMBP	Homo sapiens	Q9BTE3-2	Validated Y2H	32296183
Intra	SNW1	Q13573	FLNA	Homo sapiens	P21333-2	Y2H Array	32814053
Intra	SNW1	Q13573	FLNA	Homo sapiens	P21333-2	Validated Y2H	32814053
Intra	SNW1	Q13573	FLNA	Homo sapiens	P21333-2	Y2H Pooling	32814053
Cross	SNW1	Q13573	V-SKI	Avian erythroblastosis virus	P17863	Y2H	9569025
Cross	SNW1	Q13573	SKI	Gallus gallus	P49140	Y2H	9569025

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases

Alias

Oculopharyngeal Muscular Dystrophy

OPMD	Muscular Dystrophy, Oculopharyngeal
Dystrophy, Oculopharyngeal Muscular	Oculopharyngeal Dystrophy
Progressive Muscular Dystrophy, Oculopharyngeal Type	Muscular Dystrophy Oculopharyngeal
Dystrophy, Muscular, Oculopharyngeal

Cowden Syndrome 6

CWS6	Cowden Syndrome, Type 6

Pontocerebellar Hypoplasia

Pch	Congenital Pontocerebellar Hypoplasia
Opch	Hypoplasia, Pontocerebellar
Pontoneocerebellar Hypoplasia	Nonsyndromic Pontocerebellar Hypoplasia

Microcephaly

Microencephaly	Microcephalus
Microcephalic	Nanocephaly
Congenital Microcephaly	Brain Hypoplasia
Brain Nondevelopment	Cephalic Hypoplasia
Undeveloped Cerebrum	Undeveloped Brain
Micrencephalon	Micrencephaly

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-122054A	BPK-29 hydrochloride	Inhibitor	98.28%	Unkown
HY-122054	BPK-29	Inhibitor	99.4%	Unkown
HY-RS13521	SNW1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	SNW1	VGNC	VGNC:99243
Mus musculus	SNW1	MGD	MGI:1913604
Bos taurus	SNW1	VGNC	VGNC:35089
Canis familiaris	SNW1	VGNC	VGNC:106611
Rattus norvegicus	SNW1	RGD	RGD:1561926
Felis catus	SNW1	VGNC	VGNC:80839

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