LIN37 - lin-37 DREAM MuvB core complex component Gene

Homo sapiens

Also known as F25965; lin-37; ZK418.4

Gene ID: 55957 | Gene type: protein coding

About LIN37

This gene has 9 transcripts (splice variants) and 198 orthologues. Ubiquitous expression in testis (RPKM 7.7), placenta (RPKM 6.8) and 25 other tissues.

Summary

This gene encodes a protein expressed in the eye. [provided by RefSeq, Jul 2008]

LIN37 Products(2)

mRNA	Protein	Name
NM_001369780.1	NP_001356709.1	protein lin-37 homolog isoform 2
NM_019104.3	NP_061977.1	protein lin-37 homolog isoform 1

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	16189514	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

LIN37 Protein Structure

LIN37

0
100
200
246 a.a.

Protein Preferred Names

Protein Names

protein lin-37 homolog

antolefinin

LIN37 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	LIN37	Q96GY3	KRT40	Homo sapiens	Q6A162	Y2H Array	25416956
Intra	LIN37	Q96GY3	KRT40	Homo sapiens	Q6A162	Y2H Prey Pooling	25416956
Intra	LIN37	Q96GY3	MAGEA6	Homo sapiens	P43360	Y2H Array	32296183
Intra	LIN37	Q96GY3	MAGEA6	Homo sapiens	P43360	Y2H Prey Pooling	32296183
Intra	LIN37	Q96GY3	MAGEA6	Homo sapiens	P43360	Y2H Prey Pooling	25416956
Intra	LIN37	Q96GY3	PSTPIP1	Homo sapiens	O43586	Y2H Prey Pooling	32296183
Intra	LIN37	Q96GY3	PSTPIP1	Homo sapiens	O43586	Y2H Array	32296183
Intra	LIN37	Q96GY3	TFIP11	Homo sapiens	Q9UBB9	Y2H Prey Pooling	25416956
Intra	LIN37	Q96GY3	CDR2	Homo sapiens	Q01850	Y2H Array	25416956
Intra	LIN37	Q96GY3	MEOX2	Homo sapiens	Q6FHY5	Y2H Array	32296183
Intra	LIN37	Q96GY3	MEOX2	Homo sapiens	Q6FHY5	Y2H Prey Pooling	32296183
Intra	LIN37	Q96GY3	KIFC3	Homo sapiens	Q9BVG8	Y2H Prey Pooling	25416956
Intra	LIN37	Q96GY3	TRIM54	Homo sapiens	Q9BYV2	Y2H Prey Pooling	25416956
Intra	LIN37	Q96GY3	PNMA1	Homo sapiens	Q8ND90	Validated Y2H	25416956
Intra	LIN37	Q96GY3	TRAF1	Homo sapiens	Q13077	Y2H Prey Pooling	32296183
Intra	LIN37	Q96GY3	TRAF1	Homo sapiens	Q13077	Y2H Array	32296183
Intra	LIN37	Q96GY3	CEP70	Homo sapiens	Q8NHQ1	Validated Y2H	25416956
Intra	LIN37	Q96GY3	CEP70	Homo sapiens	Q8NHQ1	Y2H Array	25416956
Intra	LIN37	Q96GY3	CEP70	Homo sapiens	Q8NHQ1	Y2H Prey Pooling	25416956
Intra	LIN37	Q96GY3	LZTS2	Homo sapiens	Q9BRK4	Validated Y2H	25416956
Intra	LIN37	Q96GY3	LZTS2	Homo sapiens	Q9BRK4	Y2H Array	25416956
Intra	LIN37	Q96GY3	LZTS2	Homo sapiens	Q9BRK4	Y2H Prey Pooling	25416956
Intra	LIN37	Q96GY3	TEX11	Homo sapiens	Q8IYF3	Y2H Pooling	16189514
Intra	LIN37	Q96GY3	TEX11	Homo sapiens	Q8IYF3	Pull Down	16189514
Intra	LIN37	Q96GY3	CCNDBP1	Homo sapiens	O95273	Y2H Array	32296183
Intra	LIN37	Q96GY3	CCNDBP1	Homo sapiens	O95273	Y2H Prey Pooling	32296183
Intra	LIN37	Q96GY3	PDE4DIP	Homo sapiens	Q5VU43-2	Y2H Prey Pooling	32296183
Intra	LIN37	Q96GY3	PDE4DIP	Homo sapiens	Q5VU43-2	Y2H Array	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS07673	LIN37 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	LIN37	VGNC	VGNC:30892
Rattus norvegicus	LIN37	RGD	RGD:1308901
Felis catus	LIN37	VGNC	VGNC:103735
Canis familiaris	LIN37	VGNC	VGNC:53734
Mus musculus	LIN37	MGD	MGI:1922910

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