2. Gene
  3. TEX11 - testis expressed 11 Gene

TEX11 - testis expressed 11 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as TGC1; ZIP4; MZIP4; Spo22; TSGA3; ZIP4H; SPGFX2

Gene ID: 56159 | Gene type: protein coding

About TEX11

Cytogenetic location: Xq13.1 Genomic coordinates (GRCh38): X:70,511,227-70,908,711 (from NCBI)

This gene has 4 transcripts (splice variants), 145 orthologues and is associated with 2 phenotypes. Biased expression in pancreas (RPKM 5.2), testis (RPKM 5.1) and 1 other tissue.

Summary

This gene is X-linked and is expressed in only male germ cells. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

TEX11 Products(2)

mRNA Protein Name
NM_001003811.2 NP_001003811.1 testis-expressed protein 11 isoform 1
NM_031276.3 NP_112566.2 testis-expressed protein 11 isoform 2
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
16189514 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TEX11 Protein Structure

SPO22

SPO22: Meiosis protein SPO22/ZIP4 like (189 - 446)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 940 a.a.
Protein Preferred Names Protein Names

testis-expressed protein 11

ZIP4 homolog

TEX11 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
TEX11 Q8IYF3 CCDC198 Homo sapiens Q9NVL8
Y2H Prey Pooling
25416956
Intra
TEX11 Q8IYF3 CCDC198 Homo sapiens Q9NVL8
Y2H Array
25416956
Intra
TEX11 Q8IYF3 C6orf226 Homo sapiens Q5I0X4
Validated Y2H
25416956
Intra
TEX11 Q8IYF3 FBF1 Homo sapiens Q8TES7-6
Y2H Prey Pooling
25416956
Intra
TEX11 Q8IYF3 FBF1 Homo sapiens Q8TES7-6
Y2H Array
25416956
Intra
TEX11 Q8IYF3 TSC22D4 Homo sapiens Q8IV54
Validated Y2H
25416956
Intra
TEX11 Q8IYF3 TSC22D4 Homo sapiens Q8IV54
Y2H Prey Pooling
25416956
Intra
TEX11 Q8IYF3 REXO1L1P Homo sapiens Q8IX06
Validated Y2H
25416956
Intra
TEX11 Q8IYF3 REXO1L1P Homo sapiens Q8IX06
Y2H Array
25416956
Intra
TEX11 Q8IYF3 RIBC1 Homo sapiens Q8N443
Y2H Array
25416956
Intra
TEX11 Q8IYF3 RIBC1 Homo sapiens Q8N443
Validated Y2H
25416956
Intra
TEX11 Q8IYF3 COL20A1 Homo sapiens Q9P218-2
Y2H Array
25416956
Intra
TEX11 Q8IYF3 COL20A1 Homo sapiens Q9P218-2
Validated Y2H
25416956
Intra
TEX11 Q8IYF3 COL20A1 Homo sapiens Q9P218-2
Y2H Prey Pooling
25416956
Intra
TEX11 Q8IYF3 MYEF2 Homo sapiens Q9P2K5-2
Validated Y2H
25416956
Intra
TEX11 Q8IYF3 MYEF2 Homo sapiens Q9P2K5-2
Y2H Array
25416956
Intra
TEX11 Q8IYF3 PPP1R18 Homo sapiens Q6NYC8
Validated Y2H
25416956
Intra
TEX11 Q8IYF3 CXCL14 Homo sapiens O95715
Y2H Prey Pooling
25416956
Intra
TEX11 Q8IYF3 CXCL14 Homo sapiens O95715
Y2H Array
25416956
Intra
TEX11 Q8IYF3 CDKN1A Homo sapiens P38936
Validated Y2H
25416956
Intra
TEX11 Q8IYF3 SNW1 Homo sapiens Q13573
Y2H Prey Pooling
25416956
Intra
TEX11 Q8IYF3 SEPTIN1 Homo sapiens Q8WYJ6
Y2H Array
25416956
Intra
TEX11 Q8IYF3 SEPTIN1 Homo sapiens Q8WYJ6
Y2H Prey Pooling
25416956
Intra
TEX11 Q8IYF3 MAPK9 Homo sapiens P45984
Validated Y2H
25416956
Intra
TEX11 Q8IYF3 STMN2 Homo sapiens Q93045
Y2H Prey Pooling
25416956
Intra
TEX11 Q8IYF3 BEX1 Homo sapiens Q9HBH7
Y2H Array
25416956
Intra
TEX11 Q8IYF3 BEX1 Homo sapiens Q9HBH7
Y2H Prey Pooling
25416956
Intra
TEX11 Q8IYF3 DUSP21 Homo sapiens Q9H596
Validated Y2H
25416956
Intra
TEX11 Q8IYF3 DUSP21 Homo sapiens Q9H596
Y2H Array
25416956
Intra
TEX11 Q8IYF3 POM121 Homo sapiens Q96HA1
Y2H Prey Pooling
25416956
Intra
TEX11 Q8IYF3 POM121 Homo sapiens Q96HA1
Validated Y2H
25416956
Intra
TEX11 Q8IYF3 CBY2 Homo sapiens Q8NA61
Y2H Prey Pooling
25416956
Intra
TEX11 Q8IYF3 CBY2 Homo sapiens Q8NA61
Validated Y2H
25416956
Intra
TEX11 Q8IYF3 CBY2 Homo sapiens Q8NA61
Y2H Array
25416956
Intra
TEX11 Q8IYF3 BORCS8 Homo sapiens Q96FH0
Validated Y2H
25416956
Intra
TEX11 Q8IYF3 BORCS8 Homo sapiens Q96FH0
Y2H Array
25416956
Intra
TEX11 Q8IYF3 HYI Homo sapiens Q5T013
Y2H Array
25416956
Intra
TEX11 Q8IYF3 HYI Homo sapiens Q5T013
Y2H Pooling
16189514
Intra
TEX11 Q8IYF3 HYI Homo sapiens Q5T013
Validated Y2H
25416956
Intra
TEX11 Q8IYF3 FAM156B Homo sapiens Q8NDB6
Y2H Prey Pooling
25416956
Intra
TEX11 Q8IYF3 SNX7 Homo sapiens Q9UNH6
Validated Y2H
25416956
Intra
TEX11 Q8IYF3 SNX7 Homo sapiens Q9UNH6
Y2H Array
25416956
Intra
TEX11 Q8IYF3 SNX7 Homo sapiens Q9UNH6
Y2H Prey Pooling
25416956
Intra
TEX11 Q8IYF3 TBC1D22B Homo sapiens Q9NU19
Validated Y2H
25416956
Intra
TEX11 Q8IYF3 TBC1D22B Homo sapiens Q9NU19
Y2H Array
25416956
Intra
TEX11 Q8IYF3 GATAD2B Homo sapiens Q8WXI9
Validated Y2H
25416956
Intra
TEX11 Q8IYF3 MAPKBP1 Homo sapiens O60336
Y2H Prey Pooling
25416956
Intra
TEX11 Q8IYF3 MAPKBP1 Homo sapiens O60336
Validated Y2H
25416956
Intra
TEX11 Q8IYF3 MAPKBP1 Homo sapiens O60336
Y2H Array
25416956
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Spermatogenic Failure, X-Linked, 2

SPGFX2

Male Infertility From Defect In Meiosis

Spermatogenic Failure, X-Linked 2

X-Linked Spermatogenic Failure 2
Male Infertility With Azoospermia Or Oligozoospermia Due To Single Gene Mutation
Oligospermia
Spermatogenic Failure, X-Linked, 1

Sertoli Cell-Only Syndrome

Germinal Cell Aplasia

Del Castillo Syndrome

SPGFX1

X-Linked Spermatogenic Failure 1

Congenital Absence Of Germinal Epithelium Of Testes
Spermatogenic Failure

Azoospermia

Spgf

Spermatogenic Failure, Susceptibility To

Absent Sperm

Aspermatogenesis

Infertility Due To Azoospermia

Hypospermatogenesis

Azoospermatism
Vas Deferens, Congenital Bilateral Aplasia Of

Congenital Bilateral Absence Of Vas Deferens

CBAVD

Cavd

Congenital Bilateral Aplasia Of Vas Deferens

Congenital Bilateral Absence Of The Vas Deferens

Congenital Bilateral Agenesis Of Vas Deferens

Absence Of Vas Deferens

Absent Vasa

Congenital Absence Of Vas Deferens

Congenital Aplasia Of Vas Deferens

Absent Vas Deferens

Vas Deferens, Congenital Bilateral Absence
Acrodermatitis
Spermatogenic Failure 9

Male Infertility Due To Globozoospermia

SPGF9

Male Infertility Due To Round-Headed Spermatozoa

Globozoospermia, Complete

Globozoospermia, Total

Globozoospermia

Globozoospermia Syndrome

Round-Headed Sperm Syndrome

Globozoospermia Complete

Globozoospermia Total
Spermatogenic Failure 10

SPGF10

Spermatogenic Failure With Defective Sperm Annulus
Hypogonadotropic Hypogonadism

Klinefelter Syndrome

Klinefelter'S Syndrome

Xxy Syndrome

Xxy Trisomy

Hypogonadotropism

47, Xxy

Congenital Idiopathic Hypogonadotropic Hypogonadism

Isolated Congenital Gonadotropin Deficiency

47,Xxy Syndrome

47, Xxy Syndrome

Klinefelters Syndrome

Hypogonadism

Klinefelter Syndrome In Males

Klinefelter Syndrome, Unspecified

Klinefelter Syndrome Karyotype 47, Xxy
Oligoasthenoteratozoospermia

Oat

Oligoasthenoteratospermia
Spermatogenic Failure 5

Male Infertility With Large-Headed, Multiflagellar, Polyploid Spermatozoa

Infertility Associated With Multi-Tailed Spermatozoa And Excessive Dna

SPGF5

Macrocephalic Sperm Head Syndrome

Male Infertility Due To Macrozoospermia

Infertility Associated With Multitailed Spermatozoa And Excessive Dna

Macrozoospermia

Male Infertility Due To Large-Headed Multiflagellar Polyploid Spermatozoa

Infertility Associated With Multi-Tailed Spermatozoa And Excessive Deoxyribonucleic Acid

Large-Headed Multiflagellar Polyploid Spermatozoa

Male Infertility With Large-Headed Multiflagellar Polyploid Spermatozoa
Epididymo-Orchitis
Orchitis

Inflammation Of Testis

Orchititis

Mumps Orchitis
Premature Menopause

Primary Ovarian Insufficiency

Premature Ovarian Failure

Hypergonadotropic Hypogonadism

Premature Ovarian Insufficiency

Menopause - Premature

Menopause Praecox

Menopause Premature

Menopause, Premature

Female Hypergonadotropic Hypogonadism

Hypergonadotrophic Ovarian Failure

Primary Female Hypogonadism

Pof - [Premature Ovarian Failure]

Ovarian Failure

Ovarian Secretion Suppression

Ovary Hyposecretion

Ovary Secretion Deficiency

Premature Menopause Nos
Male Infertility

Infertility, Male

Infertility Male

Male Sterility

Absolute Infertility
Cryptorchidism, Unilateral Or Bilateral

Cryptorchidism

Undescended Testicle

Undescended Testis

Cryptorchism

Undescended Testicles

CRYPTO

Impaired Testicular Descent

Cryptosporidiosis

Retained Testis

Unilateral Cryptorchidism

Unilateral Undescended Testis

Nondescent Unilateral Testicle

Unilateral Cryptorchism

Ectopic Testis, Unilateral

Bilateral Cryptorchidism

Bilateral Cryptorchism

Bilateral Nondescent Testicle

Bilateral Undescended Testes

Bilateral Ectopic Testes
Kallmann Syndrome

Hypogonadism With Anosmia

Kallman'S Syndrome

Anosmic Hypogonadism

Anosmic Idiopathic Hypogonadotropic Hypogonadism

Hypogonadotropic Hypogonadism And Anosmia

Hypogonadotropic Hypogonadism-Anosmia Syndrome

Olfacto-Genital Pathological Sequence

Familial Hypogonadism With Anosmia

Kallman Syndrome

Dysplasia Olfactogenitalis Of De Morsier

Kallmann'S Syndrome

Congenital Hypogonadotropic Hypogonadism With Anosmia
Primary Ciliary Dyskinesia

Immotile Cilia Syndrome

Kartagener Syndrome

Dextrocardia Bronchiectasis And Sinusitis

Pcd

Ciliary Motility Disorders

Ciliary Motility Disorder

Immotile Ciliary Syndrome

Ciliary Dyskinesia Primary

Ics

Polynesian Bronchiectasis

Dextrocardia-Bronchiectasis-Sinusitis Syndrome

Immotile Cilia Syndrome, Kartagener Type

Primary Ciliary Dyskinesia And Situs Inversus

Primary Ciliary Dyskinesia, Kartagener Type

Siewert Syndrome

Dyskinesia, Ciliary, Primary
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14389 TEX11 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta TEX11 VGNC VGNC:78316
Bos taurus TEX11 VGNC VGNC:35760
Mus musculus TEX11 MGD MGI:1933237
Rattus norvegicus TEX11 RGD RGD:1560239
Felis catus TEX11 VGNC VGNC:82314
Canis familiaris TEX11 VGNC VGNC:47265