ZC3H10 - zinc finger CCCH-type containing 10 Gene

Homo sapiens

Also known as ZC3HDC10

Gene ID: 84872 | Gene type: protein coding

About ZC3H10

This gene has 5 transcripts (splice variants), 184 orthologues and 3 paralogues. Ubiquitous expression in testis (RPKM 6.2), ovary (RPKM 4.7) and 25 other tissues.

Summary

Enables miRNA binding activity. Involved in negative regulation of production of miRNAs involved in gene silencing by miRNA and posttranscriptional regulation of gene expression. Predicted to be active in cytoplasm and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

ZC3H10 Products(3)

mRNA	Protein	Name
NM_001303124.2	NP_001290053.1	zinc finger CCCH domain-containing protein 10
NM_001303125.2	NP_001290054.1	zinc finger CCCH domain-containing protein 10
NM_032786.3	NP_116175.1	zinc finger CCCH domain-containing protein 10

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables miRNA binding	IDA IDA: Inferred from direct assay	28431233	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	16189514	GOA

Biological Process GO Annotation	Evidence	Reference	Source
involved in negative regulation of miRNA processing	IDA IDA: Inferred from direct assay	28431233	GOA
acts upstream of positive effect post-transcriptional regulation of gene expression	IDA IDA: Inferred from direct assay	28431233	GOA

Cellular Component GO Annotation	Evidence	Reference	Source
located in nucleus	IDA IDA: Inferred from direct assay	28431233	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ZC3H10 Protein Structure

zf-CCCH

0
100
200
300
400
434 a.a.

Protein Preferred Names

Protein Names

zinc finger CCCH domain-containing protein 10

zinc finger CCCH-type domain containing 10

Related Diseases

Diseases

Alias

Optic Atrophy 11

OPA11

Atrophy, Optic, Type 11

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS15984	ZC3H10 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	ZC3H10	VGNC	VGNC:37096
Mus musculus	ZC3H10	MGD	MGI:2143670
Canis familiaris	ZC3H10	VGNC	VGNC:48550
Macaca mulatta	ZC3H10	VGNC	VGNC:79554
Rattus norvegicus	ZC3H10	RGD	RGD:1587846

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