2. Gene
  3. ZC3H10 - zinc finger CCCH-type containing 10 Gene

ZC3H10 - zinc finger CCCH-type containing 10 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as ZC3HDC10

Gene ID: 84872 | Gene type: protein coding

About ZC3H10

This gene has 5 transcripts (splice variants), 184 orthologues and 3 paralogues. Ubiquitous expression in testis (RPKM 6.2), ovary (RPKM 4.7) and 25 other tissues.

Summary

Enables miRNA binding activity. Involved in negative regulation of production of miRNAs involved in gene silencing by miRNA and posttranscriptional regulation of gene expression. Predicted to be active in cytoplasm and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

ZC3H10 Products(3)

mRNA Protein Name
NM_001303124.2 NP_001290053.1 zinc finger CCCH domain-containing protein 10
NM_001303125.2 NP_001290054.1 zinc finger CCCH domain-containing protein 10
NM_032786.3 NP_116175.1 zinc finger CCCH domain-containing protein 10
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables miRNA binding IDA
IDA: Inferred from direct assay
28431233 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
16189514 GOA
Biological Process GO Annotation Evidence Reference Source
involved in negative regulation of miRNA processing IDA
IDA: Inferred from direct assay
28431233 GOA
acts upstream of positive effect post-transcriptional regulation of gene expression IDA
IDA: Inferred from direct assay
28431233 GOA
Cellular Component GO Annotation Evidence Reference Source
located in nucleus IDA
IDA: Inferred from direct assay
28431233 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ZC3H10 Protein Structure

zf-CCCH

zf-CCCH: Zinc finger C-x8-C-x5-C-x3-H type (and similar) (137 - 159)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 434 a.a.
Protein Preferred Names Protein Names

zinc finger CCCH domain-containing protein 10

zinc finger CCCH-type domain containing 10

ZC3H10 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
ZC3H10 Q96K80 PRR20C Homo sapiens P86479
Y2H Prey Pooling
25416956
Intra
ZC3H10 Q96K80 UBE2I Homo sapiens Q7KZS0
Y2H Prey Pooling
32296183
Intra
ZC3H10 Q96K80 UBE2I Homo sapiens Q7KZS0
Y2H Array
32296183
Intra
ZC3H10 Q96K80 KRTAP8-1 Homo sapiens Q8IUC2
Y2H Array
32296183
Intra
ZC3H10 Q96K80 KRTAP8-1 Homo sapiens Q8IUC2
Y2H Prey Pooling
32296183
Intra
ZC3H10 Q96K80 PICALM Homo sapiens Q13492-3
Y2H Array
32296183
Intra
ZC3H10 Q96K80 PICALM Homo sapiens Q13492-3
Y2H Prey Pooling
32296183
Intra
ZC3H10 Q96K80 NFYA Homo sapiens P23511-2
Y2H Prey Pooling
32296183
Intra
ZC3H10 Q96K80 NFYA Homo sapiens P23511-2
Y2H Array
32296183
Intra
ZC3H10 Q96K80 POU2F1 Homo sapiens P14859-6
Y2H Prey Pooling
32296183
Intra
ZC3H10 Q96K80 POU2F1 Homo sapiens P14859-6
Y2H Array
32296183
Intra
ZC3H10 Q96K80 KRTAP6-2 Homo sapiens Q3LI66
Y2H Array
32296183
Intra
ZC3H10 Q96K80 KRTAP6-2 Homo sapiens Q3LI66
Y2H Prey Pooling
32296183
Intra
ZC3H10 Q96K80 ACTMAP Homo sapiens Q5BKX5-3
Y2H Array
32296183
Intra
ZC3H10 Q96K80 ACTMAP Homo sapiens Q5BKX5-3
Y2H Prey Pooling
32296183
Intra
ZC3H10 Q96K80 BOLL Homo sapiens Q8N9W6-4
Y2H Prey Pooling
32296183
Intra
ZC3H10 Q96K80 BOLL Homo sapiens Q8N9W6-4
Y2H Array
32296183
Intra
ZC3H10 Q96K80 RBPMS2 Homo sapiens Q6ZRY4
Y2H Prey Pooling
32296183
Intra
ZC3H10 Q96K80 RBPMS2 Homo sapiens Q6ZRY4
Y2H Array
32296183
Intra
ZC3H10 Q96K80 KRTAP6-1 Homo sapiens Q3LI64
Y2H Prey Pooling
32296183
Intra
ZC3H10 Q96K80 KRTAP6-1 Homo sapiens Q3LI64
Y2H Array
32296183
Intra
ZC3H10 Q96K80 FAM168B Homo sapiens A1KXE4-2
Y2H Array
32296183
Intra
ZC3H10 Q96K80 FAM168B Homo sapiens A1KXE4-2
Y2H Prey Pooling
32296183
Intra
ZC3H10 Q96K80 PRR20D Homo sapiens P86480
Y2H Prey Pooling
32296183
Intra
ZC3H10 Q96K80 PRR20D Homo sapiens P86480
Y2H Array
32296183
Intra
ZC3H10 Q96K80 C10orf55 Homo sapiens Q5SWW7
Y2H Prey Pooling
32296183
Intra
ZC3H10 Q96K80 C10orf55 Homo sapiens Q5SWW7
Y2H Array
32296183
Intra
ZC3H10 Q96K80 KRTAP19-1 Homo sapiens Q8IUB9
Y2H Prey Pooling
32296183
Intra
ZC3H10 Q96K80 KRTAP19-1 Homo sapiens Q8IUB9
Y2H Array
32296183
Intra
ZC3H10 Q96K80 OXER1 Homo sapiens Q8TDS5
Y2H Array
32296183
Intra
ZC3H10 Q96K80 OXER1 Homo sapiens Q8TDS5
Y2H Prey Pooling
32296183
Intra
ZC3H10 Q96K80 AOC1 Homo sapiens P19801
Y2H Array
32296183
Intra
ZC3H10 Q96K80 AOC1 Homo sapiens P19801
Y2H Prey Pooling
32296183
Intra
ZC3H10 Q96K80 FOXH1 Homo sapiens O75593
Y2H Array
32296183
Intra
ZC3H10 Q96K80 FOXH1 Homo sapiens O75593
Y2H Prey Pooling
32296183
Intra
ZC3H10 Q96K80 RNF4 Homo sapiens P78317
Y2H Array
32296183
Intra
ZC3H10 Q96K80 RNF4 Homo sapiens P78317
Y2H Prey Pooling
32296183
Intra
ZC3H10 Q96K80 FOSB Homo sapiens P53539
Y2H Prey Pooling
32296183
Intra
ZC3H10 Q96K80 FOSB Homo sapiens P53539
Y2H Array
32296183
Intra
ZC3H10 Q96K80 RBM38 Homo sapiens Q9H0Z9
Validated Y2H
32296183
Intra
ZC3H10 Q96K80 RBM38 Homo sapiens Q9H0Z9
Y2H Array
32296183
Intra
ZC3H10 Q96K80 RBM38 Homo sapiens Q9H0Z9
Y2H Prey Pooling
32296183
Intra
ZC3H10 Q96K80 PIAS2 Homo sapiens O75928-2
Y2H Array
32296183
Intra
ZC3H10 Q96K80 PIAS2 Homo sapiens O75928-2
Y2H Prey Pooling
32296183
Intra
ZC3H10 Q96K80 STAM2 Homo sapiens O75886
Y2H Array
32296183
Intra
ZC3H10 Q96K80 STAM2 Homo sapiens O75886
Y2H Prey Pooling
32296183
Intra
ZC3H10 Q96K80 MSX2 Homo sapiens P35548
Y2H Prey Pooling
32296183
Intra
ZC3H10 Q96K80 MSX2 Homo sapiens P35548
Y2H Array
32296183
Intra
ZC3H10 Q96K80 DAZAP2 Homo sapiens Q15038
Y2H Array
32296183
Intra
ZC3H10 Q96K80 DAZAP2 Homo sapiens Q15038
Y2H Prey Pooling
32296183
Intra
ZC3H10 Q96K80 DAZAP2 Homo sapiens Q15038
Y2H Array
19060904
Intra
ZC3H10 Q96K80 DAZAP2 Homo sapiens Q15038
Y2H Pooling
19060904
Intra
ZC3H10 Q96K80 PLA2G10 Homo sapiens O15496
Y2H Prey Pooling
32296183
Intra
ZC3H10 Q96K80 PLA2G10 Homo sapiens O15496
Y2H Array
32296183
Intra
ZC3H10 Q96K80 RBPMS Homo sapiens Q93062
Y2H Prey Pooling
25416956
Intra
ZC3H10 Q96K80 APPBP2 Homo sapiens Q92624
Validated Y2H
25416956
Intra
ZC3H10 Q96K80 SPMIP9 Homo sapiens Q96LM6
Y2H Prey Pooling
32296183
Intra
ZC3H10 Q96K80 SPMIP9 Homo sapiens Q96LM6
Validated Y2H
32296183
Intra
ZC3H10 Q96K80 SPMIP9 Homo sapiens Q96LM6
Y2H Array
32296183
Intra
ZC3H10 Q96K80 NCS1 Homo sapiens P62166
Y2H Prey Pooling
32296183
Intra
ZC3H10 Q96K80 NCS1 Homo sapiens P62166
Y2H Array
32296183
Intra
ZC3H10 Q96K80 CRX Homo sapiens O43186
Y2H Prey Pooling
32296183
Intra
ZC3H10 Q96K80 CRX Homo sapiens O43186
Y2H Array
32296183
Intra
ZC3H10 Q96K80 INTS11 Homo sapiens Q5TA45
Y2H Array
32296183
Intra
ZC3H10 Q96K80 INTS11 Homo sapiens Q5TA45
Y2H Prey Pooling
32296183
Intra
ZC3H10 Q96K80 TENT5B Homo sapiens Q96A09
Y2H Array
32296183
Intra
ZC3H10 Q96K80 TENT5B Homo sapiens Q96A09
Y2H Prey Pooling
32296183
Intra
ZC3H10 Q96K80 DAB1 Homo sapiens O75553
Y2H Prey Pooling
25416956
Intra
ZC3H10 Q96K80 DAB1 Homo sapiens O75553
Y2H Array
25416956
Intra
ZC3H10 Q96K80 OTX2 Homo sapiens P32243-2
Y2H Array
32296183
Intra
ZC3H10 Q96K80 OTX2 Homo sapiens P32243-2
Y2H Prey Pooling
32296183
Intra
ZC3H10 Q96K80 LASP1 Homo sapiens Q14847-2
Y2H Array
32296183
Intra
ZC3H10 Q96K80 LASP1 Homo sapiens Q14847-2
Y2H Prey Pooling
32296183
Intra
ZC3H10 Q96K80 ATXN1 Homo sapiens P54253
Y2H Array
16713569
Intra
ZC3H10 Q96K80 ATXN1 Homo sapiens P54253
Y2H
16713569
Intra
ZC3H10 Q96K80 ATXN1 Homo sapiens P54253
Y2H Prey Pooling
23275563
Intra
ZC3H10 Q96K80 KLHDC7B Homo sapiens Q96G42
Y2H Prey Pooling
32296183
Intra
ZC3H10 Q96K80 KLHDC7B Homo sapiens Q96G42
Y2H Array
32296183
Intra
ZC3H10 Q96K80 ARID5A Homo sapiens Q03989
Y2H Array
32296183
Intra
ZC3H10 Q96K80 ARID5A Homo sapiens Q03989
Y2H Prey Pooling
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Optic Atrophy 11

OPA11

Atrophy, Optic, Type 11
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15984 ZC3H10 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus ZC3H10 VGNC VGNC:37096
Mus musculus ZC3H10 MGD MGI:2143670
Canis familiaris ZC3H10 VGNC VGNC:48550
Macaca mulatta ZC3H10 VGNC VGNC:79554
Rattus norvegicus ZC3H10 RGD RGD:1587846