2. Gene
  3. Loxl2 - lysyl oxidase-like 2 Gene

Loxl2 - lysyl oxidase-like 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as 1110004B06Rik; 4930526G11Rik; 9430067E15Rik

Gene ID: 94352 | Gene type: protein coding

About Loxl2

Summary

Predicted to enable metal ion binding activity; oligosaccharide binding activity; and protein-lysine 6-oxidase activity. Involved in negative regulation of stem cell population maintenance; positive regulation of chondrocyte differentiation; and response to hypoxia. Located in collagen-containing extracellular matrix and extracellular space. Is expressed in brain. Orthologous to human LOXL2 (lysyl oxidase like 2). [provided by Alliance of Genome Resources, Apr 2022]

Loxl2 Products(1)

mRNA Protein Name
NM_033325.2 NP_201582.2 lysyl oxidase homolog 2 precursor
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in negative regulation of stem cell population maintenance IDA
IDA: Inferred from direct assay
25959397 MGI
involved in positive regulation of chondrocyte differentiation IMP
IMP: Inferred from mutant phenotype
21071451 MGI
involved in response to hypoxia IDA
IDA: Inferred from direct assay
21835952 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

lysyl oxidase homolog 2

lysyl oxidase-like protein 2

Recombinant Loxl2 Proteins

Cat. No. Product Name Accession Purity
HY-P74769 LOXL2 Protein, Mouse (HEK293, His) P58022-1 (Q26-Q776) ≥95%

Related Agents

Clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Phase
HY-107422 Lenumlostat 99.52% Phase 2
HY-107422A Lenumlostat hydrochloride / Phase 2
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P99047 Simtuzumab Inhibitor 98.69% Phase 2
Pre-clinical Phase
Bioactive Molecules (15)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-101771A (2-Chloropyridin-4-yl)methanamine hydrochloride 99.70% Unkown
HY-138625 LOX-IN-3 Inhibitor 99.97% Unkown
HY-114286A PXS-5153A monohydrochloride Inhibitor 99.67% Unkown
HY-151499A PXS-6302 hydrochloride Inhibitor 99.83% Unkown
HY-138625A LOX-IN-3 dihydrochloride Inhibitor 99.97% Unkown
HY-N0554 Escin IA Inhibitor 99.59% Unkown
HY-130242 PXS-5120A 98.12% Unkown
HY-114286 PXS-5153A Inhibitor / Unkown
HY-151498 PXS-4787 Inhibitor / Unkown
HY-151498A PXS-4787 hydrochloride Inhibitor 99.71% Unkown
HY-151499 PXS-6302 Inhibitor / Unkown
HY-138625B LOX-IN-3 dihydrochloride monohydrate Inhibitor / Unkown
HY-170573 LOXL2-IN-1 Inhibitor / Unkown
HY-170573A LOXL2-IN-1 tosylate Inhibitor 99.90% Unkown
HY-RS07742 LOXL2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Loxl2 NCBI NCBI:4017