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  4. HIV-1 inhibitor-54

HIV-1 inhibitor-54 is a potent HIV-1 inhibitor. HIV-1 inhibitor-54 has anti-HIV activity in MT-4 cells against WT HIV-1 (strain IIIB) with an EC50 value of 0.032 μM. HIV-1 inhibitor-54 can be used for the research of virus infection.

For research use only. We do not sell to patients.

HIV-1 inhibitor-54 Chemical Structure

HIV-1 inhibitor-54 Chemical Structure

CAS No. : 2771211-71-1

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HIV-1 inhibitor-54 Related Antibodies

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Description

HIV-1 inhibitor-54 is a potent HIV-1 inhibitor. HIV-1 inhibitor-54 has anti-HIV activity in MT-4 cells against WT HIV-1 (strain IIIB) with an EC50 value of 0.032 μM. HIV-1 inhibitor-54 can be used for the research of virus infection[1].

IC50 & Target[1]

HIV-1

 

In Vitro

HIV-1 inhibitor-54 (compound 4c) has potent activities against reverse transcriptase (RT) HIV-1 mutants E138K, K103 N, Y188L, Y181C, F227L+V106A and L100I with EC50 values of 0.080, 0.52, 0.67, 0.84, 2.7 and 3.3 μM, respectively[1].
HIV-1 inhibitor-54 inhibits WT HIV-1 RT activity with an IC50 value of 12 μM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

HIV-1 inhibitor-54 Related Antibodies
Molecular Weight

534.63

Formula

C27H30N6O4S
CAS No.
SMILES

CC1=CC=CC(C)=C1OC2=CC=NC(NC3CCN(CC3)C(C4=CC5=C(N4)C=CC(NS(C)(=O)=O)=C5)=O)=N2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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HIV-1 inhibitor-54 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

HIV-1 inhibitor-542771211-71-1HIVHuman immunodeficiency virusHIV-1mutantreverse transcriptaseL100IK103NY181CY188LE138KInhibitorinhibitorinhibit

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HIV-1 inhibitor-54
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HY-152539
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