1. Immunology/Inflammation
  2. PSMA
  3. HYNIC-PSMA

HYNIC-PSMA is a ligand for molecular imaging of tumors. Hynic-psma consists of two components: HYNIC (6-hydrazinonicotinamide) and PSMA (Prostate-Specific Membrane Antigen). HYNIC is a compound used to attach radioactive isotopes to targeted molecules, such as 188Re-HYNIC-PSMA. PSMA is a membrane antigen that is specifically expressed on the surface of prostate cancer cells. HYNIC-PSMA can be used in prostate cancer research.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

HYNIC-PSMA Chemical Structure

HYNIC-PSMA Chemical Structure

CAS No. : 2213408-17-2

Size Price Stock Quantity
1 mg USD 120 In-stock
5 mg USD 300 In-stock
10 mg USD 480 In-stock
50 mg   Get quote  
100 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

HYNIC-PSMA is a ligand for molecular imaging of tumors. Hynic-psma consists of two components: HYNIC (6-hydrazinonicotinamide) and PSMA (Prostate-Specific Membrane Antigen). HYNIC is a compound used to attach radioactive isotopes to targeted molecules, such as 188Re-HYNIC-PSMA. PSMA is a membrane antigen that is specifically expressed on the surface of prostate cancer cells. HYNIC-PSMA can be used in prostate cancer research[1].

In Vitro

In nuclear medicine, non-invasive imaging of prostate-specific membrane antigen (PSMA) can be achieved by binding radioisotopes to HYNIC-PSMA ligands. Tumor foci can also be located and visualized by targeting overexpressed PSMA on prostate cancer cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

567.59

Formula

C24H37N7O9

CAS No.
Appearance

Solid

Color

White to off-white

Sequence

Glu-Urea-Lys(Ahx-HYNIC)

Sequence Shortening

Glu-Urea-Lys(Ahx-HYNIC)

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 250 mg/mL (440.46 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7618 mL 8.8092 mL 17.6184 mL
5 mM 0.3524 mL 1.7618 mL 3.5237 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.7618 mL 8.8092 mL 17.6184 mL 44.0459 mL
5 mM 0.3524 mL 1.7618 mL 3.5237 mL 8.8092 mL
10 mM 0.1762 mL 0.8809 mL 1.7618 mL 4.4046 mL
15 mM 0.1175 mL 0.5873 mL 1.1746 mL 2.9364 mL
20 mM 0.0881 mL 0.4405 mL 0.8809 mL 2.2023 mL
25 mM 0.0705 mL 0.3524 mL 0.7047 mL 1.7618 mL
30 mM 0.0587 mL 0.2936 mL 0.5873 mL 1.4682 mL
40 mM 0.0440 mL 0.2202 mL 0.4405 mL 1.1011 mL
50 mM 0.0352 mL 0.1762 mL 0.3524 mL 0.8809 mL
60 mM 0.0294 mL 0.1468 mL 0.2936 mL 0.7341 mL
80 mM 0.0220 mL 0.1101 mL 0.2202 mL 0.5506 mL
100 mM 0.0176 mL 0.0881 mL 0.1762 mL 0.4405 mL
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

 

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

     

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
HYNIC-PSMA
Cat. No.:
HY-P5290
Quantity:
MCE Japan Authorized Agent: