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  3. CD3
  4. Ifinatamab

Ifinatamab is monoclonal immunoglobulin G1-kappa with anti-human B7 homolog 3 protein (Human B7-H3). Ifinatamab is a glycoforme α immunomodulateur.

For research use only. We do not sell to patients.

CAS No. : 2484870-90-6

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Based on 1 publication(s) in Google Scholar

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Ifinatamab Related Antibodies

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Description

Ifinatamab is monoclonal immunoglobulin G1-kappa with anti-human B7 homolog 3 protein (Human B7-H3). Ifinatamab is a glycoforme α immunomodulateur[1].

In Vitro

Ifinatamab can be utilized in the synthesis of ifinatamab deruxtecan (HY-P3371, I-DXd, DS-7300), an ADC that binds Ifinatamab to the DNA topoisomerase I inhibitory anti-tumor drug DXd[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Ifinatamab Related Antibodies
Clinical Trial
NCT NumberSponsorConditionStart DatePhase
NCT05280470Daiichi Sankyo, Inc.
Extensive-stage Small-cell Lung Cancer
June 17, 2022Phase 2
NCT04145622Daiichi Sankyo Co., Ltd.|Daiichi Sankyo, Inc.
Advanced Solid Tumor|Malignant Solid Tumor
November 3, 2019Phase 1|Phase 2
CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Ifinatamab]
Shipping

Shipping with dry ice.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • Human IgG1 kappa
Biological Activity
  • Immobilized Human B7-H3 Protein (ECD, His Tag) can bind Ifinatamab. The EC50 for this effect is 1.55 ng/mL.
Purity & Documentation

Purity: 99.94%

Data Sheet (254 KB) SDS (251 KB)

COA (231 KB)MS (65 KB)SDS-PAGE (97 KB)SEC-HPLC (94 KB)

Inhibitory Antibodies User Guide (602 KB)
References
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Ifinatamab Related Classifications

  • Molarity Calculator

  • Dilution Calculator

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

Ifinatamab2484870-90-6CD3Cluster of differentiation 3immunoglobulin G1-kappaglycoforme alfa immunomodulateurInhibitorinhibitorinhibit

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SAFETY DATA SHEET (SDS)

English - EN (251 KB) Français - FR (251 KB) Deutsch - DE (251 KB) Norwegian - NO (251 KB) Español - ES (251 KB) Swedish - SV (251 KB)

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