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  5. Isorhamnetin 3,7-di-O-β-D-glucopyranoside

Isorhamnetin 3,7-di-O-β-D-glucopyranoside  (Synonyms: Isorhamnetin-3,7-diglucoside; Isorhamnetin diglucoside)

Cat. No.: HY-N8196
Handling Instructions

Isorhamnetin 3,7-di-O-β-D-glucopyranoside, a major flavonoid compound, is metabolized in vivo by intestinal bacteria to isorhamnetin and that isorhamnetin plays an important role as an antioxidant.

For research use only. We do not sell to patients.

Isorhamnetin 3,7-di-O-β-D-glucopyranoside Chemical Structure

Isorhamnetin 3,7-di-O-β-D-glucopyranoside Chemical Structure

CAS No. : 6758-51-6

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Description

Isorhamnetin 3,7-di-O-β-D-glucopyranoside, a major flavonoid compound, is metabolized in vivo by intestinal bacteria to isorhamnetin and that isorhamnetin plays an important role as an antioxidant[1].

In Vivo

Isorhamnetin 3,7-di-O-β-D-glucopyranoside (10 or 20 mg/kg of body weight/day for 10 days; p.o.) to rats with streptozotocin-induced diabetes significantly reduced serum levels of glucose and 5-(hydroxymethyl)furfural (5-HMF), which is glycosylated with hemoglobin and is an indicator of oxidative stress[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male Wistar rats (5 weeks old, 120-130 g) (STZ-induced diabetic rats had higher glucose and 5-HMF levels than normal rats)[1]
Dosage: 10 or 20 mg/kg of body weight
Administration: P.o.; daily for 10 days
Result: The serum glucose levels of rats given 10 and 20 mg of orally were 510.1 and 492.4 mg/dL, respectively, whereas the control level was 574.2 mg/dL.
Molecular Weight

640.54

Formula

C28H32O17

CAS No.
SMILES

O=C(C(O[C@@H]1O[C@@H]([C@H]([C@@H]([C@H]1O)O)O)CO)=C(C2=CC(OC)=C(C=C2)O)OC3=CC(O[C@@H]4O[C@@H]([C@H]([C@@H]([C@H]4O)O)O)CO)=C5)C3=C5O

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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Product Name:
Isorhamnetin 3,7-di-O-β-D-glucopyranoside
Cat. No.:
HY-N8196
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