Marinobufogenin

Cat. No.: HY-N6574 Purity: ≥99.0%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Marinobufogenin is a strong inhibitor of Na⁺/K⁺ ATPase that has been identified in mammalian plasma.

For research use only. We do not sell to patients.

Marinobufogenin Chemical Structure

CAS No. : 470-42-8

Size	Price	Stock	Quantity
1 mg	USD 110	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 420	In-stock	Estimated Time of Arrival: December 31
10 mg		Get quote
50 mg		Get quote

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Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
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Description

Marinobufogenin is a strong inhibitor of Na⁺/K⁺ ATPase that has been identified in mammalian plasma^[1].

IC₅₀ & Target

IC50: Na⁺/K⁺ ATPase^[1]

Molecular Weight

400.51

Formula

C₂₄H₃₂O₅

CAS No.

470-42-8

Appearance

Solid

Color

White to off-white

SMILES

C[C@@]12[C@]3([C@H](O3)C[C@@H]2C(C=C4)=COC4=O)[C@]5([C@]([H])(CC1)[C@]6(C)[C@@](C[C@H](CC6)O)(CC5)O)[H]

Structure Classification

Steroids

Initial Source

Animals

toad

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (249.68 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.4968 mL	12.4841 mL	24.9682 mL
5 mM	0.4994 mL	2.4968 mL	4.9936 mL
10 mM	0.2497 mL	1.2484 mL	2.4968 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: ≥99.0%

Select Batch:

Data Sheet (273 KB) SDS (252 KB)

COA (256 KB)

Handling Instructions (2659 KB)

References

[1]. Daniel N, et al. Bufodienolides in pig plasma and urine.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.4968 mL	12.4841 mL	24.9682 mL	62.4204 mL
	5 mM	0.4994 mL	2.4968 mL	4.9936 mL	12.4841 mL
	10 mM	0.2497 mL	1.2484 mL	2.4968 mL	6.2420 mL
	15 mM	0.1665 mL	0.8323 mL	1.6645 mL	4.1614 mL
	20 mM	0.1248 mL	0.6242 mL	1.2484 mL	3.1210 mL
	25 mM	0.0999 mL	0.4994 mL	0.9987 mL	2.4968 mL
	30 mM	0.0832 mL	0.4161 mL	0.8323 mL	2.0807 mL
	40 mM	0.0624 mL	0.3121 mL	0.6242 mL	1.5605 mL
	50 mM	0.0499 mL	0.2497 mL	0.4994 mL	1.2484 mL
	60 mM	0.0416 mL	0.2081 mL	0.4161 mL	1.0403 mL
	80 mM	0.0312 mL	0.1561 mL	0.3121 mL	0.7803 mL
	100 mM	0.0250 mL	0.1248 mL	0.2497 mL	0.6242 mL