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WDR5 degrader-1 (compound 25) is a cereblon (CRBN)-recruiting WDR5 degrader. WDR5 degrader-1 selectively degraded WDR5 over the CRBN neo-substrate IKZF1.

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WDR5 degrader-1 Chemical Structure

WDR5 degrader-1 Chemical Structure

CAS No. : 3032434-45-7

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Description

WDR5 degrader-1 (compound 25) is a cereblon (CRBN)-recruiting WDR5 degrader. WDR5 degrader-1 selectively degraded WDR5 over the CRBN neo-substrate IKZF1[1].

Molecular Weight

972.98

Formula

C49H52F4N8O9

CAS No.
SMILES

CN1[C@@H](CN(C2=C(C=C(C=C2)C3=CC(C(NCCCCCCCNC(COC4=C(C5=CC=C4)C(N(C5=O)C6C(NC(CC6)=O)=O)=O)=O)=O)=CC=C3F)NC(C7=CNC(C=C7C(F)(F)F)=O)=O)C[C@@H]1C)C

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Room temperature in continental US; may vary elsewhere.

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Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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WDR5 degrader-1 Related Classifications

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Product Name:
WDR5 degrader-1
Cat. No.:
HY-162014
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