2. Anti-infection
  3. Parasite
  4. Pipercide

Pipercide is an amide of piper nigrum fruits. Pipercide has larvicidal activity to mosquito. Pipercide acts on the nervous system and induces repetitive discharge on the central nerve cord. Pipercide can be used as an insecticide.

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Pipercide Chemical Structure

Pipercide Chemical Structure

CAS No. : 54794-74-0

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Based on 1 publication(s) in Google Scholar

Pipercide Related Antibodies

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Amebae Coccidia Leishmania Mite Plasmodium Toxoplasma Trypanosoma Schistosome

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Description

Pipercide is an amide of piper nigrum fruits. Pipercide has larvicidal activity to mosquito. Pipercide acts on the nervous system and induces repetitive discharge on the central nerve cord. Pipercide can be used as an insecticide[1].

Cellular Effect
Cell Line Type Value Description References
A549 IC50
> 40 μM
Compound: 16
Antiproliferative activity against human A549 cells after 3 days by SRB assay
Antiproliferative activity against human A549 cells after 3 days by SRB assay
[PMID: 25241925]
DU-145 IC50
> 40 μM
Compound: 16
Antiproliferative activity against human DU145 cells after 3 days by SRB assay
Antiproliferative activity against human DU145 cells after 3 days by SRB assay
[PMID: 25241925]
Hepatocyte IC50
2.6 μM
Compound: 27, retrofractamide B
Hepatoprotective activity in ddY mouse hepatocytes assessed as inhibition of D-galactosamine/TNFalpha-induced cytotoxicity after 20 hrs by MTT assay relative to untreated control
Hepatoprotective activity in ddY mouse hepatocytes assessed as inhibition of D-galactosamine/TNFalpha-induced cytotoxicity after 20 hrs by MTT assay relative to untreated control
[PMID: 19775895]
HepG2 IC50
3.7 μM
Compound: Pipercide
Inhibition of human macrophage ACAT expressed in human HepG2 cells using [14C]oleoyl-CoA as substrate incubated for 20 mins prior to substrate addition measured after 25 mins by liquid scintillation counting analysis
Inhibition of human macrophage ACAT expressed in human HepG2 cells using [14C]oleoyl-CoA as substrate incubated for 20 mins prior to substrate addition measured after 25 mins by liquid scintillation counting analysis
[PMID: 23419736]
KB IC50
> 40 μM
Compound: 16
Antiproliferative activity against human KB cells after 3 days by SRB assay
Antiproliferative activity against human KB cells after 3 days by SRB assay
[PMID: 25241925]
MCF7 IC50
> 40 μM
Compound: 16
Antiproliferative activity against human MCF7 cells after 3 days by SRB assay
Antiproliferative activity against human MCF7 cells after 3 days by SRB assay
[PMID: 25241925]
MDA-MB-231 IC50
> 40 μM
Compound: 16
Antiproliferative activity against human MDA-MB-231 cells after 3 days by SRB assay
Antiproliferative activity against human MDA-MB-231 cells after 3 days by SRB assay
[PMID: 25241925]
SK-BR-3 IC50
> 40 μM
Compound: 16
Antiproliferative activity against human SK-BR-3 cells after 3 days by SRB assay
Antiproliferative activity against human SK-BR-3 cells after 3 days by SRB assay
[PMID: 25241925]
ZR-75-1 IC50
> 40 μM
Compound: 16
Antiproliferative activity against human ZR-75-1 cells after 3 days by SRB assay
Antiproliferative activity against human ZR-75-1 cells after 3 days by SRB assay
[PMID: 25241925]
Molecular Weight

355.47

Formula

C22H29NO3
CAS No.
SMILES

CC(C)CNC(/C=C/C=C/CCCC/C=C/C1=CC=C(OCO2)C2=C1)=O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Pipercide Related Classifications

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Pipercide54794-74-0Parasiteamidemosquitoinsecticidenervous systemInhibitorinhibitorinhibit

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