1. Immunology/Inflammation NF-κB Metabolic Enzyme/Protease
  2. Reactive Oxygen Species
  3. ROS-IN-1

ROS-IN-1 is a mitochondrial ROS inhibitor. ROS-IN-1 can reduce oxidative stress or inhibit reactive oxygen species (ROS) production.

For research use only. We do not sell to patients.

ROS-IN-1 Chemical Structure

ROS-IN-1 Chemical Structure

CAS No. : 298193-11-0

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
USD 55 In-stock
Solution
10 mM * 1 mL in DMSO USD 55 In-stock
Solid
5 mg USD 50 In-stock
10 mg USD 80 In-stock
50 mg   Get quote  
100 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

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  • Biological Activity

  • Purity & Documentation

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Description

ROS-IN-1 is a mitochondrial ROS inhibitor. ROS-IN-1 can reduce oxidative stress or inhibit reactive oxygen species (ROS) production[1].

In Vitro

ROS-IN-1 (Compound 40) can reduce ROS production (25.1%)[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

267.34

Formula

C13H17NO3S

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C1N(S(=O)(C2=C(C)C=C(C)C=C2C)=O)CCC1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (374.06 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.7406 mL 18.7028 mL 37.4056 mL
5 mM 0.7481 mL 3.7406 mL 7.4811 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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mg/kg

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g

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(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.14%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.7406 mL 18.7028 mL 37.4056 mL 93.5139 mL
5 mM 0.7481 mL 3.7406 mL 7.4811 mL 18.7028 mL
10 mM 0.3741 mL 1.8703 mL 3.7406 mL 9.3514 mL
15 mM 0.2494 mL 1.2469 mL 2.4937 mL 6.2343 mL
20 mM 0.1870 mL 0.9351 mL 1.8703 mL 4.6757 mL
25 mM 0.1496 mL 0.7481 mL 1.4962 mL 3.7406 mL
30 mM 0.1247 mL 0.6234 mL 1.2469 mL 3.1171 mL
40 mM 0.0935 mL 0.4676 mL 0.9351 mL 2.3378 mL
50 mM 0.0748 mL 0.3741 mL 0.7481 mL 1.8703 mL
60 mM 0.0623 mL 0.3117 mL 0.6234 mL 1.5586 mL
80 mM 0.0468 mL 0.2338 mL 0.4676 mL 1.1689 mL
100 mM 0.0374 mL 0.1870 mL 0.3741 mL 0.9351 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
ROS-IN-1
Cat. No.:
HY-153591
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