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fever

" in MedChemExpress (MCE) Product Catalog:

64

Inhibitors & Agonists

4

Biochemical Assay Reagents

1

Inhibitory Antibodies

12

Natural
Products

4

Recombinant Proteins

1

Isotope-Labeled Compounds

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-124662

    Flavivirus Dengue virus Glucosidase Infection
    IHVR-19029 is a potent endoplasmic reticulum (ER) α-glucosidases I and II inhibitor, with an IC50 of 0.48 μM for ER a-glucosidase I. IHVR-19029 efficiently blocks the replication of several hemorrhagic fever viruses, such as Dengue virus (DENV), Ebola virus (EBOV) and Rift Valley fever virus. The combination of IHVR-19029 with Favipiravir (HY-14768) improves the antiviral efficacy .
    IHVR-19029
  • HY-108308

    Methoxybutropate; AF 2259; Metoxibutropate

    Prostaglandin Receptor Metabolic Disease Inflammation/Immunology
    Ibuprofen guaiacol ester (AF 2259; Metoxibutropate) is a potent and orally active prostaglandin synthesis inhibitor. Ibuprofen guaiacol ester has the potential for the research of edema and fever .
    Ibuprofen guaiacol ester
  • HY-B1580A

    Bioban-C, meets analytical specification of E282

    Biochemical Assay Reagents Metabolic Disease
    Calcium propionate, meets analytical specification of E282 is an orally active auxiliary agent for preventing milk fever and improving the health of dairy cows. Calcium propionate can be used for research on dairy cow milk fever and subclinical hypocalcemia .
    Calcium propionate, meets analytical specification of E282
  • HY-162146

    Filovirus DNA/RNA Synthesis Infection
    NS3-IN-1 (compound 302) is a potent helicase (NS3) inhibitor. NS3-IN-1 shows an potent inhibitor for yellow fever helicase .
    NS3-IN-1
  • HY-B1580B

    Bioban-C (Pharmaceutical primary standard, USP)

    Biochemical Assay Reagents Metabolic Disease
    Calcium propionate, United States Pharmacopeia (USP) Reference Standard is an orally active auxiliary agent for preventing milk fever and improving the health of dairy cows. Calcium propionate can be used for research on dairy cow milk fever and subclinical hypocalcemia. Calcium propionate is a reference standard grade of the United States Pharmacopeia (USP) and a primary pharmaceutical standard .
    Calcium propionate, United States Pharmacopeia (USP) Reference Standard
  • HY-B1580AR

    Biochemical Assay Reagents Metabolic Disease
    Calcium propionate, meets analytical specification of E282 (Standard) is the analytical standard of Calcium propionate, meets analytical specification of E282. This product is intended for research and analytical applications. Calcium propionate, meets analytical specification of E282 is an orally active auxiliary agent for preventing milk fever and improving the health of dairy cows. Calcium propionate can be used for research on dairy cow milk fever and subclinical hypocalcemia .
    Calcium propionate, meets analytical specification of E282 (Standard)
  • HY-157023

    Others Infection
    RCB16007 is a Yellow Fever Virus (YFV) Inhibitor. RCB16007 inhibits the West Nile virus (EC50: 7.9 μM, CC50: 17 μM) .
    RCB16007
  • HY-118561

    AD-1590

    Others Inflammation/Immunology
    Bermoprofen (AD-1590) is an orally active non-steroidal anti-inflammatory agent. Bermoprofen has potent antipyretic activities with a short biological half-life. Bermoprofen is a potent antagonist of LPS-induced fever in rabbits .
    Bermoprofen
  • HY-161835

    Neurokinin Receptor Inflammation/Immunology
    SR140333B is a selective NK1 receptor inhibitor that can reduce LPS-induced fever and mitigate LPS (HY-D1056)-induced changes in brain tissue in rats .
    SR140333B
  • HY-N11665

    Others Infection
    Donasine, indole alkaloid, is a nature product with effect of reducing fever. Donasine can be isolated from the rhizomes of Arundo donax L .
    Donasine
  • HY-124618

    Flavivirus Dengue virus HCV HIV Infection
    FGI-106 is a potent and broad-spectrum inhibitor with inhibitory activity against multiple viruses. FGI-106 is active against Ebola, Rift Valley and Dengue Fever viruses with EC50s of 100 nM, 800 nM and 400-900 nM, respectively. FGI-106 also inhibits non-hemorrhagic fever viruses HCV and HIV-1 with EC50s of 200 nM and 150 nM, respectively .
    FGI-106
  • HY-124618A
    FGI-106 tetrahydrochloride
    1 Publications Verification

    Flavivirus Dengue virus HCV HIV Infection
    FGI-106 tetrahydrochloride is a potent and broad-spectrum inhibitor with inhibitory activity against multiple viruses. FGI-106 tetrahydrochloride is active against Ebola, Rift Valley and Dengue Fever viruses with EC50s of 100 nM, 800 nM and 400-900 nM, respectively. FGI-106 tetrahydrochloride also inhibits non-hemorrhagic fever viruses HCV and HIV-1 with EC50s of 200 nM and 150 nM, respectively .
    FGI-106 tetrahydrochloride
  • HY-N1751

    Others Infection
    7,11,15-Trimethyl-3-methylidenehexadecane-1,2-diol is a terpenoid that can be isolated from Eupatorium fortunei. 7,11,15-Trimethyl-3-methylidenehexadecane-1,2-diol is used in dropsy, chill, and fever research .
    (Rac)-Phytene-1,2-diol
  • HY-W012009
    2'-Deoxy-2'-fluorocytidine
    1 Publications Verification

    Influenza Virus Infection
    2'-Deoxy-2'-fluorocytidine, an nucleoside analog, is a potent inhibitor of Crimean-Congo hemorrhagic fever virus (CCHFV) replication. 2′-deoxy-2′-fluorocytidine can act synergistically with T705 to increase the potency of both compounds antiviral effects on CCHFV replication .
    2'-Deoxy-2'-fluorocytidine
  • HY-B0970

    4-Diphenylmethoxy-1-methylpiperidine hydrochloride

    Histamine Receptor Neurological Disease Endocrinology
    Diphenylpyraline hydrochloride is a potent histamine H1?receptor antagonist. Diphenylpyraline hydrochloride acts as an orally active antihistamine agent?with antimuscarinic and antiallergic effects. Diphenylpyraline hydrochloride can be used for the relief of allergic conditions including rhinitis and hay fever, and in pruritic skin disorders in vivo.
    Diphenylpyraline hydrochloride
  • HY-107431

    Histamine Receptor Inflammation/Immunology
    Diphenylpyraline is a potent histamine H1 receptor antagonist. Diphenylpyraline acts as an orally active antihistamine agent with antimuscarinic and antiallergic effects. Diphenylpyraline can be used for the research of allergic diseases, including rhinitis and hay fever, and pruritic skin disorders et.al .
    Diphenylpyraline
  • HY-160877

    Filovirus Infection
    EBOV-IN-2 (Compound 2) is an inhibitor of Ebola virus (EBOV) with IC50 values of 0.37 μM and 2.54 μM against Ebola virus glycoprotein pseudotype virus (pEBOV) and African swine fever virus (ASFV), respectively .
    EBOV-IN-2
  • HY-N3185

    Cholinesterase (ChE) Infection Metabolic Disease Inflammation/Immunology Cancer
    N-Methylcalycinine is a nature product with AChE inhibitory activity. N-Methylcalycinine can be isolated from the roots of Stephania epigaea. N-Methylcalycinine can be used for the research of asthma, cancer, dysentery, fever, hyperglycemia, intestinal complaints, inflammation, sleep disturbances, tuberculosis and so on .
    N-Methylcalycinine
  • HY-W011518

    Influenza Virus Infection
    2′-Deoxy-2′-fluoroguanosine, a nucleoside analog, is a potent inhibitor of influenza virus strains, with an EC90 of <0.35 μM for influenza virus A and B strains. 2′-Deoxy-2′-fluoroguanosine significantly inhibits replication of influenza virus in the upper respiratory tract, resulting in amelioration of fever and nasal inflammation .
    2′-Deoxy-2′-fluoroguanosine
  • HY-B1080
    Tilorone dihydrochloride
    2 Publications Verification

    HIF/HIF Prolyl-Hydroxylase Influenza Virus Infection Neurological Disease
    Tilorone dihydrochloride is an orally active interferon (IFN) inducer with broad-spectrum antiviral activities. Tilorone dihydrochloride possesses robust anti-Severe fever with thrombocytopenia syndrome virus (SFTSV) activity in vitro and in vivo through stimulation of host innate immunity. Tilorone dihydrochloride can penetrate the blood-brain barrier to activate HIF in the CNS .Tilorone dihydrochloride exhibits an inhibitory activity with EC50 of 230 nM against Ebola virus (EBOV) .
    Tilorone dihydrochloride
  • HY-B1080R

    HIF/HIF Prolyl-Hydroxylase Influenza Virus Infection Neurological Disease
    Tilorone (dihydrochloride) (Standard) is the analytical standard of Tilorone (dihydrochloride). This product is intended for research and analytical applications. Tilorone dihydrochloride is an orally active interferon (IFN) inducer with broad-spectrum antiviral activities. Tilorone dihydrochloride possesses robust anti-Severe fever with thrombocytopenia syndrome virus (SFTSV) activity in vitro and in vivo through stimulation of host innate immunity. Tilorone dihydrochloride can penetrate the blood-brain barrier to activate HIF in the CNS .Tilorone dihydrochloride exhibits an inhibitory activity with EC50 of 230 nM against Ebola virus (EBOV) .
    Tilorone dihydrochloride (Standard)
  • HY-N4217

    Others Others
    Saikosaponin I is a triterpene saponin extracted from Bupleurum falcatum L. Saikosaponin can be used to treat fever, inflammation, liver disease, and nephritis .
    Saikosaponin I
  • HY-139602C

    Flavivirus Infection
    (-)-JNJ-A07 is a potent and selective DENV inhibitor with an EC50 value of 31 nM .
    (-)-JNJ-A07
  • HY-135731AS

    Isotope-Labeled Compounds COX Drug Metabolite Inflammation/Immunology
    4-Methylamino antipyrine-d3 (hydrochloride) is deuterium labeled 4-Methylamino antipyrine (hydrochloride). 4-Methylamino antipyrine hydrochloride is an active metabolite of Metamizole. Metamizole is a pyrazolone non-steroidal anti-inflammatory drug (NSAID) and inhibits COX. Metamizole is an nonopioid analgesic agent and can be used for pain and fever[1][2][3]. 4-Methylamino antipyrine hydrochloride has analgesic, antipyretic, and relatively weak antiinflammatory properties[2].
    4-Methylamino antipyrine-d3 hydrochloride
  • HY-100174

    NSC294836

    Others Neurological Disease
    W-2429 (NSC294836) is considerably more effective than acetylsalicylic acid in inhibiting carrageenan-induced edema and in reducing brewer's yeast-induced fever in rats .
    W-2429
  • HY-W040672

    Dytransin

    COX Inflammation/Immunology
    Ibufenac (Dytransin) is an analog of Ibuprofen. Ibuprofen is a non-steroidal anti-rheumatoid agen and non-selective COX inhibitor used to research mild-moderate pain, fever, and inflammation.
    Ibufenac
  • HY-A0191

    (+)-Brompheniramine; (S)-Brompheniramine

    Endogenous Metabolite Histamine Receptor Inflammation/Immunology
    Dexbrompheniramine is an orally active H1 receptor antagonist. Dexbrompheniramine is an antihistamine that reduces the effects of natural chemical histamine. Dexbrompheniramine can be used for the research of hay fever and urticaria .
    Dexbrompheniramine
  • HY-A0191A

    (+)-Brompheniramine maleate; (S)-Brompheniramine maleate

    Endogenous Metabolite Histamine Receptor Inflammation/Immunology
    Dexbrompheniramine maleate is an orally active H1 receptor antagonist. Dexbrompheniramine maleate is an antihistamine that reduces the effects of natural chemical histamine. Dexbrompheniramine maleate can be used for the research of hay fever and urticaria .
    Dexbrompheniramine maleate
  • HY-N7252

    Bacterial Infection
    Daphnin is one of the major coumarin bioactive components with antibacterial activity. Daphnin is isolated from the whole herb of Daphne odora (Thunb.), which is a folk medicine in China for the relief of fever .
    Daphnin
  • HY-156979

    SARS-CoV HCV Infection
    RBT-9 prevents progression to severe COVID-19 and organ failure. RBT-9 also has antiviral effects, as demonstrated in several enveloped viruses, including influenza, HCV, dengue, and yellow fever .
    RBT-9
  • HY-124082

    Lauryl gallate

    Others Infection
    Dodecyl gallate (Lauryl gallate) has been widely used as an antioxidant in food manufacturing, as well as in the pharmaceutical and cosmetic industries. Dodecyl gallate also is active against a highly relevant animal virus such as African swine fever virus (ASFV) .
    Dodecyl gallate
  • HY-W008662

    Filovirus Infection
    2'-Deoxy-5'-O-DMT-2'-fluorouridine, a nucleoside analogue, is a 5’-O-DMTr-5-FUDR derivative with potent anti-yellow fever (YFV) activity .
    2'-Deoxy-5'-O-DMT-2'-fluorouridine
  • HY-W121901

    (S)-Naproxen-β-D-glucuronide

    COX Inflammation/Immunology
    Naproxen glucuronide ((S)-Naproxen-β-D-glucuronide) is a non-selective COX inhibitor. Naproxen glucuronide, a metabolite of naproxen, is a nonsteroidal anti-inflammatory drug (NSAID) of the propionic acid class (the same as ibuprofen) that relieves pain, fever, swelling, and stiffness .
    Naproxen glucuronide
  • HY-124871

    Arenavirus Infection
    LASV inhibitor 3.3 is a Lassa fever virus (LASV) inhibitor. LASV inhibitor 3.3 binds with LASV glycoprotein (GP) and promotes virus membrane fusion and infection. LASV inhibitor 3.3 can be used for LASV infection research .
    LASV inhibitor 3.3
  • HY-N7252R

    Bacterial Infection
    Daphnin (Standard) is the analytical standard of Daphnin. This product is intended for research and analytical applications. Daphnin is one of the major coumarin bioactive components with antibacterial activity. Daphnin is isolated from the whole herb of Daphne odora (Thunb.), which is a folk medicine in China for the relief of fever .
    Daphnin (Standard)
  • HY-18649B

    BCX4430 dihydrochloride; Immucillin-A dihydrochloride

    Flavivirus Infection
    Galidesivir (BCX4430; Immucillin-A) dihydrochloride is a broad-spectrum RNA virus inhibitor that can inhibit Ebola and yellow fever virus (Flavivirus) infections. Galidesivir has potent antiviral activity against tick-borne encephalitis virus (TBEV) and also inhibits the proliferation of many other medically important flaviviruses .
    Galidesivir dihydrochloride
  • HY-133588

    Endogenous Metabolite Metabolic Disease
    4-Formylaminoantipyrine is an excreted metabolite of aminophenazone. Aminophenazone is a pyrazolone with analgesic, anti-inflammatory, and antipyretic effects in vivo .
    4-Formylaminoantipyrine
  • HY-117721

    Glucokinase Infection Inflammation/Immunology
    IHVR-11029 is a small molecule inhibitor of ER α-glucosidases, with an EC50 of 0.09 μM .
    IHVR-11029
  • HY-133588R

    Endogenous Metabolite Metabolic Disease
    4-Formylaminoantipyrine (Standard) is the analytical standard of 4-Formylaminoantipyrine. This product is intended for research and analytical applications. 4-Formylaminoantipyrine is an excreted metabolite of aminophenazone. Aminophenazone is a pyrazolone with analgesic, anti-inflammatory, and antipyretic effects in vivo .
    4-Formylaminoantipyrine (Standard)
  • HY-B0641

    4-Biphenylacetic acid

    COX Inflammation/Immunology
    Felbinac is a metabolite of fenbufen, an orally active nonsteroidal anti-inflammatory agent and a cyclooxygenase (COX) inhibitor with an IC50 of 865.68 nM for COX1 and 976 nM for COX2. Felbinac reduces the production of prostaglandins by inhibiting COX to relieve pain, reduce inflammation and reduce fever. Felbinac can inhibit CHIKV viral activity .
    Felbinac
  • HY-135731

    COX Drug Metabolite Inflammation/Immunology
    4-Methylamino antipyrine is an active metabolite of Metamizole. Metamizole is a pyrazolone non-steroidal anti-inflammatory drug (NSAID) and inhibits COX. Metamizole is an nonopioid analgesic agent and can be used for pain and fever . 4-Methylamino antipyrine has analgesic, antipyretic, and relatively weak antiinflammatory properties .
    4-Methylamino antipyrine
  • HY-135731A

    COX Drug Metabolite Inflammation/Immunology
    4-Methylamino antipyrine hydrochloride is an active metabolite of Metamizole. Metamizole is a pyrazolone non-steroidal anti-inflammatory drug (NSAID) and inhibits COX. Metamizole is an nonopioid analgesic agent and can be used for pain and fever . 4-Methylamino antipyrine hydrochloride has analgesic, antipyretic, and relatively weak antiinflammatory properties .
    4-Methylamino antipyrine hydrochloride
  • HY-124082R

    Others Infection
    Dodecyl gallate (Standard) is the analytical standard of Dodecyl gallate. This product is intended for research and analytical applications. Dodecyl gallate (Lauryl gallate) has been widely used as an antioxidant in food manufacturing, as well as in the pharmaceutical and cosmetic industries. Dodecyl gallate also is active against a highly relevant animal virus such as African swine fever virus (ASFV) .
    Dodecyl gallate (Standard)
  • HY-B1212
    Broxyquinoline
    1 Publications Verification

    Dibromohydroxyquinoline; 5,7-Dibromo-8-hydroxyquinoline

    Parasite Influenza Virus Infection
    Broxyquinoline (Dibromohydroxyquinoline) is an effective inhibitor of severe fever with thrombocytopenia syndrome virus (SFTSV) with an IC50 of 5.8 µM. Additionally, Broxyquinoline is an inhibitor of CpACBP1 with an IC50 of 64.9 μM. CpACBP1 is a fatty acyl-CoA binding protein of Cryptosporidium parvum, thus Broxyquinoline has the potential to inhibit parasite growth. Broxyquinoline shows promise for research in the field of infectious diseases .
    Broxyquinoline
  • HY-W040235

    Others Others
    Fluazuron is an insect growth regulator with activity against larvae of Amblyomma sculptum. Fluazuron exhibits 100% efficacy by interfering with the molting process. Fluazuron has shown rapid absorption and slow metabolism in experiments. The use of Fluazuron offers a potential preventive measure for the control of Brazilian spotted fever. The results of Fluazuron offer good prospects for the development of feed products containing FLU to control ticks in free-living capybaras .
    Fluazuron
  • HY-14670

    ML 1785713

    COX Inflammation/Immunology
    Firocoxib (ML 1785713) is a potent, selective and orally active COX-2 inhibitor with an IC50 of 0.13 μM. Firocoxib shows 58-fold more selective for COX-2 than COX-1 (IC50 of 7.5 μM). Firocoxib has anti-inflammatory effects .
    Firocoxib
  • HY-B1201

    3,3',5-Triiodothyroacetic acid

    Flavivirus Thyroid Hormone Receptor TNF Receptor Endocrinology
    Tiratricol is an orally available thyroid hormone analog that inhibits pituitary thyroid-stimulating hormone secretion. Tiratricol is an intracellular toxin neutralizer that inhibits LPS and lipid A cytotoxicity with IC50s of 20 μM and 32 μM, respectively. Tiratricol reduces TNF production in lipopolysaccharide-stimulated macrophages. Tiratricol also has antiviral activity and is an inhibitor of yellow fever virus (Flavivirus). It can bind to the RdRp domain of the viral NS5 protein to hinder YFV replication. .
    Tiratricol
  • HY-135731AR

    COX Drug Metabolite Inflammation/Immunology
    4-Methylamino antipyrine (hydrochloride) (Standard) is the analytical standard of 4-Methylamino antipyrine (hydrochloride). This product is intended for research and analytical applications. 4-Methylamino antipyrine hydrochloride is an active metabolite of Metamizole. Metamizole is a pyrazolone non-steroidal anti-inflammatory drug (NSAID) and inhibits COX. Metamizole is an nonopioid analgesic agent and can be used for pain and fever . 4-Methylamino antipyrine hydrochloride has analgesic, antipyretic, and relatively weak antiinflammatory properties .
    4-Methylamino antipyrine hydrochloride (Standard)
  • HY-135731R

    COX Drug Metabolite Inflammation/Immunology
    4-Methylamino antipyrine (Standard) is the analytical standard of 4-Methylamino antipyrine. This product is intended for research and analytical applications. 4-Methylamino antipyrine is an active metabolite of Metamizole. Metamizole is a pyrazolone non-steroidal anti-inflammatory drug (NSAID) and inhibits COX. Metamizole is an nonopioid analgesic agent and can be used for pain and fever . 4-Methylamino antipyrine has analgesic, antipyretic, and relatively weak antiinflammatory properties .
    4-Methylamino antipyrine (Standard)
  • HY-W339645

    (S)-Naproxen ethyl ester

    Others Inflammation/Immunology
    Naproxen ethyl ester ((S)-Naproxen ethyl ester) is a nonsteroidal anti-inflammatory drug with activity in relieving pain, fever, swelling and stiffness. Naproxen ethyl ester exerts its effects by inhibiting non-selective cyclooxygenase (COX). The R-(-)-isomer of Naproxen ethyl ester shows stronger immunogenicity, and the Michaelis-Menten parameter of its catalytic reaction is K(M)=6.67 mM, and the catalytic efficiency is 5.8 x 10^4 times higher than that of the non-catalytic reaction .
    Naproxen ethyl ester

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