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Results for "

inflammation-related

" in MedChemExpress (MCE) Product Catalog:

66

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2

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11

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1

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5

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15

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4

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Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W091541
    4-Hydroxy-1H-indole-3-carbaldehyde

    4-Hydroxyindole-3-carboxaldehyde

    		 Endogenous Metabolite Others Inflammation/Immunology
    4-Hydroxy-1H-indole-3-carbaldehyde (4-Hydroxyindole-3-carboxaldehyde) is a plant metabolite. 4-Hydroxy-1H-indole-3-carbaldehyde can be isolated from Capparis spinosa L. 4-Hydroxy-1H-indole-3-carbaldehyde can be used in the synthesis of fluorescent probe. 4-Hydroxy-1H-indole-3-carbaldehyde can be used in the study of inflammation-related diseases .
    4-Hydroxy-1H-indole-3-carbaldehyde
  • HY-14857
    Carotegrast

    HCA2969

    		 Integrin Inflammation/Immunology
    Carotegrast (HCA2969) is an orally active α4 integrin inhibitor with anti-inflammatory activity. Carotegrast can be used in the research of inflammation-related diseases, such as ulcerative colitis .
    Carotegrast
  • HY-P991123
    Bocunebart

    		Adenylate Cyclase Inflammation/Immunology
    Bocunebart is a humanized monoclonal antibody targeting human adenylate cyclase-activating polypeptide (ADCYAP1). Bocunebart exerts anti-inflammatory activity by specifically binding to ADCYAP1 and inhibiting related inflammatory signaling pathways. Bocunebart is promising for research of inflammation-related diseases .
    Bocunebart
  • HY-P991138
    Firsekibart

    		Interleukin Related Inflammation/Immunology
    Firsekibart is an immunoglobulin G4-λ2 monoclonal antibody targeting human interleukin 1β (IL-1β). Firsekibart is promising for research of inflammation-related diseases, such as rheumatoid arthritis and inflammatory bowel disease .
    Firsekibart
  • HY-P991127
    Claseprubart

    		Complement System Inflammation/Immunology
    Claseprubart is a monoclonal antibody targeting human complement C1s. Claseprubart specifically binds to complement C1s to inhibit the activation of the complement system, exerting immunosuppressive activity. Claseprubart is promising for research of autoimmune diseases and inflammation-related diseases .
    Claseprubart
  • HY-P991161
    Tanruprubart

    		Complement System Inflammation/Immunology
    Tanruprubart is a monoclonal antibody targeting human complement C1q. Tanruprubart specifically binds to complement C1q, inhibiting the initiation of the classical complement activation pathway and exerting immunosuppressive activity. Tanruprubart is promising for research of autoimmune diseases and inflammation-related diseases .
    Tanruprubart
  • HY-105983A
    CBS-1114 hydrochloride

    		Lipoxygenase Inflammation/Immunology
    CBS-1114 hydrochloride is a potent 5-lipoxygenase inhibitor. CBS-1114 hydrochloride has the potential for inflammation and inflammation-related disorders research .
    CBS-1114 hydrochloride
  • HY-144195
    MIF-IN-3

    		Macrophage migration inhibitory factor (MIF) Inflammation/Immunology
    MIF-IN-3 is a migration inhibitory factor (MIF) inhibitor extracted from patent WO2021258272A1 compound 31. MIF-IN-3 can be used for the research of immune inflammation-related diseases .
    MIF-IN-3
  • HY-144194
    MIF-IN-2

    		Macrophage migration inhibitory factor (MIF) Inflammation/Immunology
    MIF-IN-2 is a migration inhibitory factor (MIF) inhibitor extracted from patent WO2021258272A1 compound 1. MIF-IN-2 can be used for the research of immune inflammation-related diseases .
    MIF-IN-2
  • HY-165027
    DL-1′-Acetoxychavicol acetate

    		NO Synthase COX Others
    DL-1′-Acetoxychavicol acetate is a compound with anti-inflammatory and anticancer preventive potential that inhibits the activities of NOX, iNOS, and COX-2 in inflammatory cells and exhibits preventive activity in multiple inflammation-related cancer models.
    DL-1′-Acetoxychavicol acetate
  • HY-146564A
    HP210

    		Glucocorticoid Receptor Inflammation/Immunology
    HP210 is a selective glucocorticoid receptor modulator (SGRM). HP210 can inhibit the mRNA expression of IL-1β and IL-6. HP210 has the potential to study inflammation-related diseases .
    HP210
  • HY-118915
    FR 106969

    A26771E

    		 Endogenous Metabolite Inflammation/Immunology
    FR 106969 (A26771E) is a platelet activating factor antagonist with anti-inflammatory activity. FR 106969 can be used to alleviate inflammatory responses. FR 106969 has shown potential inhibitory effects on inflammation-related diseases in studies .
    FR 106969
  • HY-123490
    Regrelor disodium

    INS50589

    		 P2Y Receptor Inflammation/Immunology
    Regrelor disodium (INS 50589) is a platelet P2Y12 receptor antagonist. Regrelor disodium is a well-tolerated, reversible ADP competitive antagonist. Regrelor disodium inhibits cell proliferation. Regrelor disodium can be used in inflammation-related research .
    Regrelor disodium
  • HY-W127549
    Petroselinic acid sodium

    cis-6-Octadecenoic acid

    		 Biochemical Assay Reagents Others
    Petroselinic acid sodium is an organic compound belonging to the class of carboxylic acids. Petroselinic acid sodium has several applications in the cosmetic and personal care industries, especially as an emulsifier and conditioning agent in skin and hair care products. In addition, it has potential utility in inhibiting inflammation-related diseases and cancer.
    Petroselinic acid sodium
  • HY-N8167
    Plantanone B

    Kaempferol 3-O-rhamnosylgentiobioside

    		 COX Inflammation/Immunology
    Plantanone B is a moderate antioxidant-agent with an IC50 of 169.8±5.2 μM. Plantanone B shows significant ovine COX-1 and moderate COX-2 inhibitory activities. Plantanone B has the potential for inflammation-related diseases research .
    Plantanone B
  • HY-120606
    A-78773

    		Lipoxygenase Inflammation/Immunology
    A-78773 is a 5-lipoxygenase inhibitor. A-78773 can inhibit the formation of LTB4 in human whole blood and human neutrophils, with IC50 values of 85 nM and 20 nM, respectively. A-78773 can be used in the study of inflammation-related diseases .
    A-78773
  • HY-21075
    3-Furanoic acid

    		Endogenous Metabolite Inflammation/Immunology
    3-Furanoic acid is an active unit, and its derivatives have a wide range of anti-inflammatory activities. 3-Furanoic acid-related derivatives can target inflammation-related signaling pathways and inhibit the proliferation of synovial fibroblasts to exert immunomodulatory effects .
    3-Furanoic acid
  • HY-149953
    FABP4-IN-2

    		FABP Inflammation/Immunology
    FABP4-IN-2 (Compd 10g) is a selective and orally active FABP4 inhibitor with the Ki values of 0.51 μM for FABP4, 33.01 μM for FABP3. FABP4-IN-2 can be used in the research of inflammation-related diseases .
    FABP4-IN-2
  • HY-148457
    Avacincaptad pegol

    		Complement System Infection Inflammation/Immunology
    Avacincaptad pegol, which is a pegylated aptamer, has garnered significant attention as a C5 complement inhibitor that may reduce inflammation-related retinal pigment epithelium (RPE) damage. Avacincaptad pegol caqn be used for the research of stargardt macular dystrophy (STGD1) and geographic atrophy (GA) .
    Avacincaptad pegol
  • HY-10594
    Letaxaban

    TAK-442

    		 Factor Xa Cardiovascular Disease Inflammation/Immunology
    Letaxaban (TAK-442) is an orally active and selective direct FXa inhibitor. Letaxaban is a drug with dual anticoagulant and anti-inflammatory activity that works by directly inhibiting FXa and by intervening in the PAR1 signaling pathway. Letaxaban can be used in the study of thrombotic diseases, cardiovascular diseases and inflammation-related diseases .
    Letaxaban
  • HY-B1428
    2-Ethoxybenzamide

    Ethenzamide

    		 Tyrosinase Reactive Oxygen Species PERK Neurological Disease Inflammation/Immunology Cancer
    2-Ethoxybenzamide (Ethenzamide) is a nonsteroidal anti-inflammatory agent that shows analgesic and antipyretic effects. 2-Ethoxybenzamide induces melanin synthesis via cAMP response element-binding protein (CREB) phosphorylation. 2-Ethoxybenzamide can be used in the research of hypopigmentation and inflammation-related diseases .
    2-Ethoxybenzamide
  • HY-119086
    L-651392

    		Lipoxygenase Inflammation/Immunology
    L-651392 is an orally active and specific 5-lipoxygenase inhibitor that inhibits the production of leukotrienes. L-651392 controls the inflammatory process in Escherichia coli pyelonephritis by preventing inflammatory cells from reaching the site of infection and protecting the renal tubules from inflammation-related damage during pyelonephritis .
    L-651392
  • HY-N0278
    Anemonin

    Pulsatilla camphor; Anemonine; trans-Anemonin

    		 PKC NO Synthase Inflammation/Immunology
    Anemonin (Pulsatilla camphor), a selective iNOS inhibitor, is also a PKC-θ inhibitor. Anemonin can significantly inhibit the translation or protein stability of PKC-θ protein. Anemonin also ameliorates dextran sodium sulfate-induced acute ulcerative colitis (UC) in mice. Anemonin can be used in the research of inflammation-related diseases .
    Anemonin
  • HY-N12481
    Cephalandole B

    		Others Inflammation/Immunology
    Cephalandole B is an indigo alkaloid that has the activity of inhibiting IL-17A gene expression. Cephalandole B significantly inhibited the activity of IL-17A luciferase reporter gene in Jukat cells, and this inhibitory effect was dose-dependent. Cephalandole B may have important application prospects in inflammation-related research .
    Cephalandole B
  • HY-125859A
    Myeloperoxidase, human white blood cells

    MPO

    		 Bacterial Inflammation/Immunology
    Myeloperoxidase, human white blood cells (MPO) is a peroxidase. In Myeloperoxidase, human white blood cells mediate oxidative stress by promoting the production of reactive oxygen species (ROS) and active nitrogen (RNS), regulating the polarization and inflammation-related signaling pathways of microglia and neutrophils. Myeloperoxidase, human white blood cells has antibacterial activity .
    Myeloperoxidase, human white blood cells
  • HY-N2963
    Broussonin E

    		ERK p38 MAPK JAK STAT TNF Receptor Interleukin Related COX Arginase Inflammation/Immunology
    Broussonin E is a phenolic compound and shows anti-inflammatory activity. Broussonin E can suppress inflammation by modulating macrophages activation statevia inhibiting the ERK and p38 MAPK and enhancing JAK2-STAT3 signaling pathway. Broussonin E can be used for the research of inflammation-related diseases such as atherosclerosis .
    Broussonin E
  • HY-W127331
    Cholesterol hexanoate

    		Liposome Others
    Cholesterol hexanoate is an organic compound belonging to the class of esters. It is formed from the reaction between cholesterol and caproic acid. Cholesterol hexanoate has several applications in the pharmaceutical industry, particularly as a bioactive compound with potential research potential for improving a range of medical conditions, such as high cholesterol and inflammation-related diseases. Additionally, it has potential applications as a food additive to improve texture and stability.
    Cholesterol hexanoate
  • HY-W127351
    Cholesterol decanoate

    		Liposome Others
    Cholesterol decanoate is an organic compound belonging to the class of esters. It is formed from the reaction between cholesterol and capric acid. Cholesterol decanoate has several applications in the pharmaceutical industry, particularly as a bioactive compound with potential research potential for improving a range of medical conditions, such as high cholesterol and inflammation-related diseases. Additionally, it has potential applications as a food additive to improve texture and stability.
    Cholesterol decanoate
  • HY-W127562
    2-Tridecenoic acid

    		Biochemical Assay Reagents Others
    2-Tridecenoic acid is an organic compound belonging to the class of fatty acids. It has a slightly rancid smell and is commonly found in a variety of foods, such as dairy products and meats. 2-Tridecenoic acid has various applications in the chemical and pharmaceutical industries, especially as an intermediate in the synthesis of various chemicals and pharmaceuticals. Additionally, it has potential utility in inhibiting bacterial infections and inflammation-related diseases.
    2-Tridecenoic acid
  • HY-W127349
    Cholesterol n-Octanoate

    		Liposome Others
    Cholesterol n-Octanoate is an organic compound belonging to the class of esters. It is formed from the reaction between cholesterol and caprylic acid. Cholesterol n-octanoate has various applications in the pharmaceutical industry, notably as a bioactive compound with potential research potential to improve a range of medical conditions, such as high cholesterol and inflammation-related diseases. Additionally, it has potential applications as a food additive to improve texture and stability.
    Cholesterol n-Octanoate
  • HY-W127491
    trans-9-Octadecenol

    Elaidyl alcohol

    		 Biochemical Assay Reagents Others
    Trans-9-Octadecenol is an organic compound belonging to the group of alcohols. It has a mild fatty smell and is commonly found in a variety of foods, such as meat and dairy products. Trans-9-Octadecenol has several applications in the flavor and fragrance industry, especially as a fragrance agent in products such as perfumes, colognes and air fresheners. In addition, it has potential utility in inhibiting inflammation-related diseases and cancer.
    trans-9-Octadecenol
  • HY-171454
    DA-1241

    		GPR119 Metabolic Disease Inflammation/Immunology
    DA-1241 is a GPR119 agonist. DA-1241 reduces macrophage differentiation through downregulation of NFκB signaling by activating GPR119. DA-1241, alone and in combination with a DPP4 inhibitor, reduces liver inflammation and restores inflammation-related liver gene expression. DA-1241 can be used for the research of metabolic dysfunction-associated steatohepatitis (MASH) .
    DA-1241
  • HY-W011215
    Dihexyl phthalate

    		Apoptosis Reactive Oxygen Species Inflammation/Immunology
    Dihexyl phthalate is one of the commonly used phthalate esters in various plastics and consumer products. Dihexyl phthalate is classified as a priority pollutant and an endocrine disruptor. Dihexyl phthalate can induce reactive oxygen species (ROS) accumulation, promote inflammation, and lead to significant increases in apoptosis and inflammation-related gene expression levels. Dihexyl phthalate can cause testicular atrophy and is a reproductive toxicant .
    Dihexyl phthalate
  • HY-N1818
    Deoxysappanone B

    3-Deoxysappanone B

    		 p38 MAPK Neurological Disease Inflammation/Immunology
    Deoxysappanone B (3-Deoxysappanone B) is a homoisoflavone compound isolated from Caesalpinia sappan L (Lignum Sappan). Deoxysappanone B has anti-neuroinflammatory and neuroprotective effects and inhibits the production of neuroinflammatory mediators by blocking the IκB kinase (IKK)-NF-κB and p38/ERK MAPK pathways. Deoxysappanone B can be used in disease studies of neuritis and inflammation-related neurological damage .
    Deoxysappanone B
  • HY-N0278A
    (Rac)-Anemonin

    (Rac)-Pulsatilla camphor; (Rac)-Anemonine

    		 PKC NO Synthase Inflammation/Immunology
    (Rac)-Anemonin ((Rac)-Pulsatilla camphor) is the diastereoisomer of Anemonin (HY-N0278). Anemonin (Pulsatilla camphor), a selective iNOS inhibitor, is also a PKC-θ inhibitor. Anemonin can significantly inhibit the translation or protein stability of PKC-θ protein. Anemonin also ameliorates dextran sodium sulfate-induced acute ulcerative colitis (UC) in mice. Anemonin can be used in the research of inflammation-related diseases .
    (Rac)-Anemonin
  • HY-B1428R
    2-Ethoxybenzamide (Standard)

    Ethenzamide (Standard)

    		 Tyrosinase Reactive Oxygen Species PERK Neurological Disease Inflammation/Immunology Cancer
    2-Ethoxybenzamide (Standard) is the analytical standard of 2-Ethoxybenzamide (HY-B1428). 2-Ethoxybenzamide (Ethenzamide) is a nonsteroidal anti-inflammatory agent that shows analgesic and antipyretic effects. 2-Ethoxybenzamide induces melanin synthesis via cAMP response element-binding protein (CREB) phosphorylation. 2-Ethoxybenzamide can be used in the research of hypopigmentation and inflammation-related diseases .
    2-Ethoxybenzamide (Standard)
  • HY-W127403
    Cholesteryl elaidate

    Cholesteryl trans-9-octadecenoate

    		 Biochemical Assay Reagents Others
    Cholesteryl elaidate is an organic compound belonging to the class of esters. It is formed from the reaction between cholesterol and elaidic acid, producing a white crystalline solid with a mildly sweet taste. Cholesteryl elaidate has several applications in the pharmaceutical industry, particularly as a bioactive compound with potential research potential for improving a range of medical conditions, such as high cholesterol and inflammation-related diseases. Additionally, it has potential applications as a food additive to improve texture and stability.
    Cholesteryl elaidate
  • HY-124526
    Chiauranib

    Ibcasertib; CS2164

    		 VEGFR PDGFR c-Kit Aurora Kinase c-Fms Cancer
    Chiauranib (CS2164) is an orally active multi-target inhibitor against tumor angiogenesis. Chiauranib potently inhibits the angiogenesis-related kinases (VEGFR1, VEGFR2, VEGFR3, PDGFRα and c-Kit), mitosis-related kinase Aurora B, and chronic inflammation-related kinase CSF-1R, with IC50 values ranging from 1-9 nM. Chiauranib has strongly anticancer effects .
    Chiauranib
  • HY-117403
    AB-FUBICA

    		Cannabinoid Receptor Potassium Channel
    AB-FUBICA (Compound 13) is a CB1 and CB2 receptor agonist that activates G-protein coupled inwardly rectifying potassium channels (GIRK) by binding to CB1 and CB2 receptors, displaying notable cannabinoid-like activity. AB-FUBICA has EC50 values of 21 nM for CB1 and 15 nM for CB2. AB-FUBICA may be suitable for studying pain management, neurodegenerative diseases, and inflammation-related mechanisms .
    AB-FUBICA
  • HY-W127366
    7-Octen-1-ol

    		Biochemical Assay Reagents Others
    7-Octen-1-ol is an organic compound belonging to the group of alcohols. It has a strong mushroom-like smell and is commonly found in a variety of foods, such as mushrooms, soybeans, and peanuts. 7-Octen-1-ol has various applications in the flavor and fragrance industry, especially as a fragrance agent in products such as perfumes, colognes and air fresheners. In addition, it has potential utility in inhibiting inflammation-related diseases and cancer.
    7-Octen-1-ol
  • HY-W101301
    cis-5-Octen-1-ol

    		Biochemical Assay Reagents Others
    cis-5-Octen-1-ol is an organic compound belonging to alcohols. It has a strong earthy smell and is commonly found in a variety of foods such as fruits, vegetables and spices. cis-5-Octen-1-ol has various applications in the flavor and fragrance industry, especially as a flavoring and aroma enhancer in products such as perfume, cologne and baked goods. In addition, it has potential utility in inhibiting inflammation-related diseases and cancer.
    cis-5-Octen-1-ol
  • HY-163032
    FABP4-IN-3

    		FABP Cardiovascular Disease Metabolic Disease Inflammation/Immunology
    FABP4-IN-3 (compound C3) is a highly selective FABP4 inhibitor (FABP4 Ki = 25 ± 3 a nM, FABP3 Ki = 15.03 μM) which exhibits a 601-fold selectivity over FABP3. FABP4-IN-3 also shows metabolic stability and potent cellular anti-inflammatory activity, making it promising to get involved in the research of metabolic disease, cardiac dysfunction and inflammation-related disease .
    FABP4-IN-3
  • HY-161735
    CXCR4-IN-3

    		CXCR Inflammation/Immunology
    CXCR4-IN-3 (compound XVI) is an orally active and potent inhibitor targeting the inflammation-related receptor CXCR4, with an IC50 of 3.2 nM. CXCR4-IN-3 exhibits potent antichemotactic activity, at 79.19±2.33% inhibition. CXCR4-IN-3 shows anti-inflammatory activity. CXCR4-IN-3 can be used for IBD (inflammatory bowel disease) research .
    CXCR4-IN-3
  • HY-W424851
    DPQ hydrochloride

    6,7-Dimethoxy-2-(1-piperazinyl)-4-quinazolinamine hydrochloride

    		 PARP Infection Inflammation/Immunology
    DPQ hydrochloride is a blood-brain barrier permeable and selective PARP-1 inhibitor that blocks PARP-1-mediated DNA damage repair and NAD +/ATP consumption, thereby inhibiting excessive inflammatory responses. DPQ hydrochloride inhibits NF-κB pathway activation, reduces the expression of pro-inflammatory factors (such as TNF-α, IL-6) and oxidative stress. DPQ hydrochloride can be used in inflammation-related studies of acute lung injury, myocardial infarction, and neurodegenerative diseases .
    DPQ hydrochloride
  • HY-114869
    DPQ
    1 Publications Verification

    		 PARP Neurological Disease
    DPQ is a blood-brain barrier permeable and selective PARP-1 inhibitor that blocks PARP-1-mediated DNA damage repair and NAD +/ATP consumption, thereby inhibiting excessive inflammatory responses. DPQ inhibits NF-κB pathway activation, reduces the expression of pro-inflammatory factors (such as TNF-α, IL-6) and oxidative stress. DPQ can be used in inflammation-related studies of acute lung injury, myocardial infarction, and neurodegenerative diseases .
    DPQ
  • HY-W127349R
    Cholesterol n-Octanoate (Standard)

    		Liposome Others
    Cholesterol n-Octanoate (Standard) is the analytical standard of Cholesterol n-Octanoate. This product is intended for research and analytical applications. Cholesterol n-Octanoate is an organic compound belonging to the class of esters. It is formed from the reaction between cholesterol and caprylic acid. Cholesterol n-octanoate has various applications in the pharmaceutical industry, notably as a bioactive compound with potential research potential to improve a range of medical conditions, such as high cholesterol and inflammation-related diseases. Additionally, it has potential applications as a food additive to improve texture and stability.
    Cholesterol n-Octanoate (Standard)
  • HY-173129
    Anti-inflammatory agent 97

    		NF-κB Toll-like Receptor (TLR) Inflammation/Immunology
    Anti-inflammatory agent 97 (Compound 1l), an anti-inflammation agent, can also inhibit oxidative stress. Anti-inflammatory agent 97 can inhibit the colonic shortening and suppress inflammatory symptoms of the colonic tissue in the DSS (HY-116282C)-induced ulcerative colitis mice model. Anti-inflammatory agent 97 can regulate the inflammation-related TLR4/NF-κB signaling pathway and the oxidative stress-related Nrf2/HO-1 signaling pathway .
    Anti-inflammatory agent 97
  • HY-14562
    TBPB

    		mAChR Amyloid-β Neurological Disease Inflammation/Immunology
    TBPB (tert-butyl peroxybenzoate) is a highly selective, blood-brain-permeable M1 mAChR allosteric agonist (EC50=289 nM) with anti-schizophrenia and anti-inflammatory activities. TBPB can enhance the sensitivity of M1 receptors to acetylcholine, activate downstream signaling pathways, and inhibit the release of pro-inflammatory cytokines (TNF-α, IL-6). TBPB can regulate the processing of amyloid and can be used in the study of neurodegenerative diseases (such as Alzheimer's disease) and inflammation-related diseases (such as sepsis) .
    TBPB
  • HY-W040255
    1-Palmitoyl-2-glutaryl-sn-glycero-3-phosphocholine

    PGPC

    		 Biochemical Assay Reagents
    1-Palmitoyl-2-glutaryl-sn-glycero-3-phosphocholine (PGPC) is a bioactive molecule that has the activity of inducing inflammation, proliferation or apoptosis. 1-Palmitoyl-2-glutaryl-sn-glycero-3-phosphocholine can be used as an important tool to study the response of vascular smooth muscle cells and macrophages. The application areas of 1-Palmitoyl-2-glutaryl-sn-glycero-3-phosphocholine include the mechanism research of inflammation-related diseases and compound development.
    1-Palmitoyl-2-glutaryl-sn-glycero-3-phosphocholine
  • HY-120920
    UNC9995

    		Dopamine Receptor Inflammation/Immunology
    UNC9995 is a β-arrestin2-biased agonist of dopamine receptor Drd2. UNC9995 inhibits NLRP3 inflammasome activation by enhancing β-arrestin2-NLRP3 interaction, thus prevents neuronal degeneration. Futhermore, UNC9995 activates the Drd2/β-arrestin2 signaling to prevent inflammation-related genes transcription-induced by JAK/STAT3. UNC9995 improves depressive behavior in mouse model, and improves astrocytes dysfunctions .
    UNC9995

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