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ATP (Standard)

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117

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B2176R
    ATP (Standard)

    Adenosine 5'-triphosphate (Standard)

    		 Reference Standards Endogenous Metabolite Metabolic Disease Inflammation/Immunology
    ATP (Standard) is the analytical standard of ATP. This product is intended for research and analytical applications. ATP (Adenosine 5'-triphosphate) is a central component of energy storage and metabolism in vivo. ATP provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP is an important endogenous signaling molecule in immunity and inflammation . In Vitro: ATP (5 mM; 1 hour) co-treatment with LPS (1 μg/mL) has a synergistic effect on the activation of the NLRP3 inflammasome in HGFs .
    ATP (2 mM; 0.5-24 hours) induces secretion of IL-1β, KC and MIP-2 from BMDMs in a caspase-1 activation-dependent manner .
    ATP promotes neutrophil chemotaxis in vitro .
    In Vivo: ATP (50 mg/kg; i.p.) protects mice against bacterial infection in vivo .
    ATP induces the secretion of IL-1β, KC and MIP-2 and neutrophils recruitment in vivo .
    ATP (Standard)
  • HY-14881AR
    Bedaquiline fumarate (Standard)

    R403323 (Standard); TMC207 fumarate (Standard); R207910 fumarate (Standard)

    		 Reference Standards Bacterial Antibiotic Infection
    Bedaquiline (fumarate) (Standard) is the analytical standard of Bedaquiline (fumarate). This product is intended for research and analytical applications. Bedaquiline fumarate, a diarylquinoline antibiotic that targets ATP synthase, is effective for the treatment of Mycobacterium tuberculosis infections.
    Bedaquiline fumarate (Standard)
  • HY-W010918R
    Adenosine 5'-diphosphate (Standard)

    Adenosine diphosphate (Standard); ADP (Standard)

    		 Reference Standards Endogenous Metabolite Others
    Adenosine 5'-diphosphate (Standard) is the analytical standard of Adenosine 5'-diphosphate. This product is intended for research and analytical applications. Adenosine 5'-diphosphate (Adenosine diphosphate) is a nucleoside diphosphate. Adenosine 5'-diphosphate is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate induces human platelet aggregation and inhibits stimulated adenylate cyclase by an action at P2T-purinoceptors. In Vitro: Adenosine 5'-diphosphate consists of the pyrophosphate group, the pentose sugar ribose, and the nucleobase adenine. Adenosine 5'-diphosphate is the product of ATP dephosphorylation by ATPases. ADP is converted back to ATP by ATP synthases. ATP is an important energy transfer molecule in cells. Adenosine 5'-diphosphate is utilized in a wide number of cellular processes, including respiration, biosynthetic reactions, motility, and cell division.
    Adenosine 5'-diphosphate (Standard)
  • HY-W010735R
    ATP disodium salt hydrate (Standard)

    Adenosine 5'-triphosphate disodium salt hydrate (Standard)

    		 Reference Standards Endogenous Metabolite Metabolic Disease Inflammation/Immunology Cancer
    ATP (disodium salt hydrate) (Standard) is the analytical standard of ATP (disodium salt hydrate). This product is intended for research and analytical applications. ATP disodium salt hydrate (Adenosine 5'-triphosphatedisodium salt hydrate) is a central component of energy storage and metabolism in vivo, provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP disodium salt hydrate is an important endogenous signaling molecule in immunity and inflammation .
    ATP disodium salt hydrate (Standard)
  • HY-B0345AR
    ATP disodium (Standard)

    Adenosine 5'-triphosphate disodium (Standard); Disodium adenosine triphosphate (Standard)

    		 Reference Standards Endogenous Metabolite Metabolic Disease Inflammation/Immunology Cancer
    ATP disodium salt (Standard) is the analytical standard of ATP disodium salt (HY-B0345A). This product is intended for research and analytical applications. ATP disodium salt (Adenosine 5'-triphosphate disodium salt) is a central component of energy storage and metabolism in vivo, provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP disodium salt is an important endogenous signaling molecule in immunity and inflammation .
    ATP disodium (Standard)
  • HY-138247R
    β-Lactamase-IN-2 (Standard)

    EX-A4764 (Standard); UUN51204 (Standard)

    		 Beta-lactamase Reference Standards Bacterial Antibiotic Infection
    ATP (disodium salt) (Standard) is the analytical standard of ATP (disodium salt). This product is intended for research and analytical applications. ATP disodium salt (Adenosine 5'-triphosphate disodium salt) is a central component of energy storage and metabolism in vivo, provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP disodium salt is an important endogenous signaling molecule in immunity and inflammation .
    β-Lactamase-IN-2 (Standard)
  • HY-B1140R
    Diazoxide (Standard)

    Sch-6783 (Standard); SRG-95213 (Standard)

    		 Reference Standards Potassium Channel Autophagy Cardiovascular Disease Cancer
    Diazoxide (Standard) is the analytical standard of Diazoxide. This product is intended for research and analytical applications. Diazoxide (Sch-6783) is an ATP-sensitive potassium channel activator, has the potential for hyperinsulinism treatment.
    Diazoxide (Standard)
  • HY-17451R
    Glibornuride (Standard)

    		Reference Standards Potassium Channel Metabolic Disease
    Glibornuride (Standard) is the analytical standard of Glibornuride. This product is intended for research and analytical applications. Glibornuride is a blocker of ATP-sensitive K+ channels (KATP channel) with a pKi of 5.75 . Antidiabetic agent .
    Glibornuride (Standard)
  • HY-B0183R
    Ellagic acid (Standard)

    		Reference Standards Casein Kinase Reactive Oxygen Species (ROS) Endogenous Metabolite SHP2 Neurological Disease Cancer
    Ellagic acid (Standard) is the analytical standard of Ellagic acid. This product is intended for research and analytical applications. Ellagic acid is a natural antioxidant, and acts as a potent and ATP-competitive inhibitor of CK2 and SHP2, with an IC50 of 40 nM and a Ki of 20 nM.
    Ellagic acid (Standard)
  • HY-12357R
    Bempedoic acid (Standard)

    ETC-1002 (Standard); ESP-55016 (Standard)

    		 ATP Citrate Lyase AMPK Metabolic Disease
    Bempedoic acid (Standard) is the analytical standard of Bempedoic acid. This product is intended for research and analytical applications. Bempedoic acid (ETC-1002) is an ATP-citrate lyase (ACL) inhibitor . Bempedoic acid (ETC-1002) activates AMPK .
    Bempedoic acid (Standard)
  • HY-B0753R
    Gliclazide (Standard)

    S1702 (Standard); SE1702 (Standard)

    		 Reference Standards Potassium Channel Cardiovascular Disease
    Gliclazide (Standard) is the analytical standard of Gliclazide. This product is intended for research and analytical applications. Gliclazide (S1702) is a whole-cell beta-cell ATP-sensitive potassium currents blocker with an IC50 of 184 nM. Gliclazide is used as an antidiabetic .
    Gliclazide (Standard)
  • HY-12283R
    Rostafuroxin (Standard)

    		Na+/K+ ATPase RSV Cardiovascular Disease
    Rostafuroxin (Standard) is the analytical standard of Rostafuroxin. This product is intended for research and analytical applications. Rostafuroxin (PST 2238), a digitoxigenin derivative, is an orally active and potent Na+,K+-ATPase (ATP1A1) antognist. Rostafuroxin binds specifically to the ATP1A1 extracellular domain and blocks respiratory syncytial virus (RSV)-triggered EGFR Tyr845 phosphorylation. Rostafuroxin has antihypertensive and anti-RSV activity .
    Rostafuroxin (Standard)
  • HY-N0021R
    Verbascoside (Standard)

    Acteoside (Standard); Kusaginin (Standard); TJC160 (Standard)

    		 Reference Standards PKC Apoptosis Bacterial HSV Neurological Disease Inflammation/Immunology Cancer
    Verbascoside (Standard) is the analytical standard of Verbascoside. This product is intended for research and analytical applications. Verbascoside is isolated from Acanthus mollis, acts as an ATP-competitive inhibitor of PKC, with an IC50 of 25 μM, and has antitumor, anti-inflammatory and antineuropathic pain activity.
    Verbascoside (Standard)
  • HY-13343
    ZM 336372
    2 Publications Verification

    		 Raf Apoptosis Cancer
    ZM 336372 is a potent inhibitor of the protein kinase c-Raf. The IC50 value is 0.07 μM in the standard assay, which contains 0.1 mM ATP.
    ZM 336372
  • HY-13328R
    Sapanisertib (Standard)

    		mTOR Autophagy Cancer
    Sapanisertib (Standard) is the analytical standard of Sapanisertib. This product is intended for research and analytical applications. Sapanisertib (INK-128; MLN0128; TAK-228) is an orally available, ATP-dependent mTOR1/2 inhibitor with an IC50 of 1 nM for mTOR kinase.
    Sapanisertib (Standard)
  • HY-14660R
    Dabrafenib (Standard)

    GSK2118436A (Standard); GSK2118436 (Standard)

    		 Reference Standards Raf Cancer
    Dabrafenib (Standard) is the analytical standard of Dabrafenib. This product is intended for research and analytical applications. Dabrafenib (GSK2118436A) is an ATP-competitive inhibitor of Raf with IC50s of 5 nM and 0.6 nM for C-Raf and B-Raf V600E, respectively .
    Dabrafenib (Standard)
  • HY-12432R
    Gilteritinib (Standard)

    ASP2215 (Standard)

    		 Reference Standards FLT3 TAM Receptor Cancer
    Gilteritinib (Standard) is the analytical standard of Gilteritinib. This product is intended for research and analytical applications. Gilteritinib (ASP2215) is a potent and ATP-competitive FLT3/AXL inhibitor with IC50s of 0.29 nM/0.73 nM, respectively.
    Gilteritinib (Standard)
  • HY-N1469R
    Kaurenoic acid (Standard)

    		Reference Standards Potassium Channel Neurological Disease Inflammation/Immunology
    Kaurenoic acid (Standard) is the analytical standard of Kaurenoic acid. This product is intended for research and analytical applications. Kaurenoic acid is a diterpene from Sphagneticola trilobata, inhibits Inflammatory Pain by the inhibition of cytokine production and activation of the NO–cyclic GMP–PKG–ATP-sensitive potassium channel signaling pathway .
    Kaurenoic acid (Standard)
  • HY-116482R
    Desmedipham (Standard)

    		Insecticide Herbicide Reference Standards Others
    Desmedipham (Standard) is the analytical standard of Desmedipham. This product is intended for research and analytical applications. Desmedipham is a selective systemic phenyl-carbamate herbicide. Desmedipham acts by disrupting CO2 fixation and the production of intermediary energy components-ATP and NADPH2 and inhibition of Hill reaction .
    Desmedipham (Standard)
  • HY-12432AR
    Gilteritinib hemifumarate (Standard)

    		FLT3 TAM Receptor Cancer
    Gilteritinib hemifumarate (Standard) is the analytical standard of Gilteritinib hemifumarate. This product is intended for research and analytical applications. Gilteritinib (ASP2215) hemifumarate is a potent and ATP-competitive FLT3/AXL inhibitor with IC50 of 0.29 nM/0.73 nM, respectively.
    Gilteritinib hemifumarate (Standard)
  • HY-10512R
    AR-A014418 (Standard)

    AR 0133418 (Standard); GSK 3β inhibitor VIII (Standard); AR 014418 (Standard)

    		 Reference Standards GSK-3 Metabolic Disease Cancer
    AR-A014418 (Standard) is the analytical standard of AR-A014418. This product is intended for research and analytical applications. AR-A014418 is a potent, selective and ATP-competitive GSK3β inhibitor (IC50=104 nM; Ki=38 nM) .
    AR-A014418 (Standard)
  • HY-10474R
    Torkinib (Standard)

    PP 242 (Standard)

    		 Reference Standards mTOR Autophagy Mitophagy Apoptosis Cancer
    Torkinib (Standard) is the analytical standard of Torkinib. This product is intended for research and analytical applications. Torkinib (PP 242) is a selective and ATP-competitive mTOR inhibitor with an IC50 of 8 nM . PP242 inhibits both mTORC1 and mTORC2 with IC50s of 30 nM and 58 nM, respectively .
    Torkinib (Standard)
  • HY-14896R
    Opicapone (Standard)

    BIA 9-1067 (Standard)

    		 Reference Standards COMT Neurological Disease
    Opicapone (Standard) is the analytical standard of Opicapone. This product is intended for research and analytical applications. Opicapone (BIA 9-1067) is a potent third-generation catechol-O-methyltransferase (COMT) inhibitor for the research of Parkinson's disease and motor fluctuations. Opicapone decreases the ATP content of the cells with an IC50 of 98 μM .
    Opicapone (Standard)
  • HY-130353R
    Desethylamiodarone hydrochloride (Standard)

    N-desethylamiodarone hydrochloride(Standard); LB 33020 hydrochloride (Standard)

    		 Reference Standards Potassium Channel Autophagy Cardiovascular Disease
    Desethylamiodarone (hydrochloride) (Standard) is the analytical standard of Desethylamiodarone (hydrochloride). This product is intended for research and analytical applications. Desethylamiodarone hydrochloride (N-desethylamiodarone hydrochloride) is a major active metabolite of Amiodarone. Desethylamiodarone hydrochloride is formed by CYP3A isoenzymes. Amiodarone is an antiarrhythmic agent for inhibition of ATP-sensitive potassium channel with an IC50 of 19.1 μM .
    Desethylamiodarone hydrochloride (Standard)
  • HY-W008807R
    Phosphoenolpyruvic acid potassium (Standard)

    Phosphoenolpyruvate potassium (Standard)

    		 Reference Standards Endogenous Metabolite Metabolic Disease
    Phosphoenolpyruvic acid potassium (Standard) (Potassium 1-carboxyvinyl hydrogenphosphate (Standard)) is the analytical standard of Phosphoenolpyruvic acid potassium (HY-W008807). This product is intended for research and analytical applications. Phosphoenolpyruvic acid potassium is a glycolysis metabolite with a high-energy phosphate group. Phosphoenolpyruvic acid potassium is involved in glycolysis and gluconeogenesis, and used as energy source to produce ATP, under the energy-limited conditions. Phosphoenolpyruvic acid potassium also exhibits cytoprotective and anti-oxidative properties.
    Phosphoenolpyruvic acid potassium (Standard)
  • HY-N7126R
    Citronellal (Standard)

    		Reference Standards Potassium Channel Neurological Disease
    Citronellal (Standard) is the analytical standard of Citronellal. This product is intended for research and analytical applications. Citronellal is a monoterpenea from the essential oils in various aromatic species of plants, with depressant, and antinociceptive properties. Citronellal attenuates mechanical nociception, mediated in part by the NO-cGMP-ATP-sensitive K? channel pathway .
    Citronellal (Standard)
  • HY-12866R
    Larotrectinib (Standard)

    LOXO-101 (Standard); ARRY-470 (Standard)

    		 Reference Standards Trk Receptor Apoptosis Cancer
    Larotrectinib (Standard) is the analytical standard of Larotrectinib. This product is intended for research and analytical applications. Larotrectinib (LOXO-101) is an ATP-competitive oral, selective inhibitor of the tropomyosin-related kinase (TRK) family receptors, with low nanomolar 50% inhibitory concentrations against all three isoforms (TRKA, B, and C).
    Larotrectinib (Standard)
  • HY-N2522R
    Carboxyatractyloside dipotassium (Standard)

    Gummiferin dipotassium (Standard)

    		 Reference Standards Mitochondrial Metabolism Calcium Channel Reactive Oxygen Species (ROS) Neurological Disease
    Carboxyatractyloside (dipotassium) (Standard) is the analytical standard of Carboxyatractyloside dipotassium (HY-N2522). This product is intended for research and analytical applications. Carboxyatractyloside dipotassium is a diterpenoid. Carboxyatractyloside dipotassium can be isolated from plants of the genus Xanthium. Carboxyatractyloside dipotassium is an ADP/ATP carrier inhibitor, inhibiting mitochondrial ADP/ATP transport. Carboxyatractyloside dipotassium promotes ROS production, induces Ca 2+ release, and leads to mitochondrial dysfunction. Carboxyatractyloside dipotassium induces lethargy, weakness, and epileptic seizures in rats .
    Carboxyatractyloside dipotassium (Standard)
  • HY-10961R
    Momelotinib (Standard)

    		JAK Autophagy Apoptosis Cancer
    Momelotinib (Standard) is the analytical standard of Momelotinib. This product is intended for research and analytical applications. Momelotinib (CYT387) is an ATP-competitive inhibitor of JAK1/JAK2 with IC50a of 11 nM and 18 nM,respectively. CYT387 shows much less activity against JAK3.
    Momelotinib (Standard)
  • HY-12012R
    SB 216763 (Standard)

    		GSK-3 Autophagy Neurological Disease Cancer
    SB 216763 (Standard) is the analytical standard of SB 216763. This product is intended for research and analytical applications. SB 216763 is potent, selective and ATP-competitive GSK-3 inhibitor with IC50s of 34.3 nM for both GSK-3α and GSK-3β.
    SB 216763 (Standard)
  • HY-10337R
    Brivanib (Standard)

    BMS-540215 (Standard)

    		 Reference Standards VEGFR Autophagy Cancer
    Brivanib (Standard) is the analytical standard of Brivanib. This product is intended for research and analytical applications. Brivanib (BMS-540215) is an ATP-competitive inhibitor against VEGFR2 with an IC50 of 25 nM, and has moderate potency against VEGFR-1 and FGFR-1, but >240-fold against PDGFR-β .
    Brivanib (Standard)
  • HY-B0887BR
    (-)-trans-Permethrin (Standard)

    (-)-trans-NRDC-143 (Standard); (1S)-trans-Permethrin (Standard)

    		 Insecticide Reference Standards Others
    Atractyloside (potassium salt) (Standard) is the analytical standard of Atractyloside (potassium salt). This product is intended for research and analytical applications. Atractyloside potassium salt is a toxic diterpenoid glycoside that can be isolated from the fruits of Xanthium sibiricum. Atractyloside potassium salt is a powerful and specific inhibitor of mitochondrial ADP/ATP transport. Atractyloside potassium salt inhibits chloride channels from mitochondrial membranes of rat heart .
    (-)-trans-Permethrin (Standard)
  • HY-108573R
    P-1075 (Standard)

    		Potassium Channel Cardiovascular Disease
    P-1075 (Standard) is the analytical standard of P-1075. This product is intended for research and analytical applications. P-1075 is a potent activator of sulfonylurea receptor 2-associated ATP-sensitive potassium channels (SUR2-KIR6), with an EC50 value of 45 nM for SUR2B-KIR6 channel activation . P-1075 also P1075 opens mitochondrial K(ATP) channels and generates reactive oxygen species resulting in cardioprotection of rabbit hearts .
    P-1075 (Standard)
  • HY-10583R
    Y-27632 dihydrochloride (Standard)
    Maximum Cited Publications
    331 Publications Verification

    		 ROCK Organoid Reference Standards Cancer
    Y-27632 (dihydrochloride) (Standard) is the analytical standard of Y-27632 (dihydrochloride). Y-27632 dihydrochloride is an orally active and ATP-competitive ROCK (Rho-kinase) inhibitor (ROCK-I Ki=220 nM; ROCK-II Ki=300 nM). Y-27632 dihydrochloride shows antiepileptic effects .
    Y-27632 dihydrochloride (Standard)
  • HY-B0112R
    Minoxidil (Standard)

    U10858 (Standard)

    		 Reference Standards Potassium Channel Endogenous Metabolite Cardiovascular Disease Cancer
    Minoxidil (Standard) is the analytical standard of Minoxidil. This product is intended for research and analytical applications. Minoxidil (U10858) is an ATP-sensitive potassium (KATP) channel opener, a potent oral antihypertensive agent and a peripheral vasodilator that promotes vasodilation also affects hair growth. Minoxidil is also a potent inhibitor of soybean lipoxygenaseare with an IC50 of 20 μM .
    Minoxidil (Standard)
  • HY-18963R
    Lavendustin A (Standard)

    RG-14355 (Standard)

    		 Reference Standards EGFR Cancer
    Lavendustin A (Standard) is the analytical standard of Lavendustin A. This product is intended for research and analytical applications. Lavendustin A (RG-14355) is a potent, selective and ATP-competitive inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase, with an IC50 of 11 nM. Lavendustin A does not inhibit protein kinase A or C. Lavendustin A can suppress VEGF-induced angiogenesis[1][2].
    Lavendustin A (Standard)
  • HY-B0501R
    Danofloxacin mesylate (Standard)

    CP 76136-27 (Standard)

    		 Reference Standards Bacterial Antibiotic Infection
    Danofloxacin mesylate (Standard) is the analytical standard of Danofloxacin mesylate. This product is intended for research and analytical applications. Danofloxacin mesylate (CP 76136-27) is a fluoroquinolone used as a veterinary drug. Danofloxacin mesylate has a broad spectrum of bactericidal activity, mainly inhibiting the DNA cycloenzyme of the bacteria. In addition, Danofloxacin mesylate is a substrate for ATP-dependent efflux transporters (P-gp and MRP2) .
    Danofloxacin mesylate (Standard)
  • HY-10962R
    Momelotinib sulfate (Standard)

    		JAK Autophagy Apoptosis Cancer
    Momelotinib (sulfate) (Standard) is the analytical standard of Momelotinib (sulfate). This product is intended for research and analytical applications. Momelotinib sulfate (CYT387 sulfate salt) is an ATP-competitive inhibitor of JAK1/JAK2 with IC50 of 11 nM/18 nM, 10-fold selectivity versus JAK3 (IC50=155 nM).
    Momelotinib sulfate (Standard)
  • HY-11007R
    GNF-2 (Standard)

    		Bcr-Abl SARS-CoV Cancer
    GNF-2 (Standard) is the analytical standard of GNF-2. This product is intended for research and analytical applications. GNF-2 is a highly selective, allosteric, non-ATP competitive inhibitor of Bcr-Abl. GNF-2 inhibits Ba/F3.p210 proliferation with an IC50 of 138 nM .
    GNF-2 (Standard)
  • HY-W013636AR
    2-Ketoglutaric acid Sodium (Standard)

    Alpha-Ketoglutaric acid Sodium (Standard)

    		 Reference Standards Tyrosinase Endogenous Metabolite Neurological Disease Metabolic Disease
    2-Ketoglutaric acid (Sodium) (Standard) is the analytical standard of 2-Ketoglutaric acid Sodium (HY-W013636A). This product is intended for research and analytical applications. 2-Ketoglutaric acid (Alpha-Ketoglutaric acid) Sodium (Standard) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid Sodium also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid Sodium is a reversible inhibitor of tyrosinase (IC50=15 mM) .
    2-Ketoglutaric acid Sodium (Standard)
  • HY-B0341R
    Nicorandil (Standard)

    SG-75 (Standard)

    		 Reference Standards Potassium Channel Cardiovascular Disease
    Nicorandil (Standard) is the analytical standard of Nicorandil. This product is intended for research and analytical applications. Nicorandil (SG-75) is a potent potassium channel activator and targets vascular nucleoside diphosphate-dependent K + channels and cardiac ATP-sensitive K + channels (KATP). Nicorandil is a nicotinamide ester with vasodilatory and cardioprotective effects and has the potential for angina and forischemic heart diseases .
    Nicorandil (Standard)
  • HY-N2306R
    Aclacinomycin A (Standard)

    Aclarubicin (Standard)

    		 Reference Standards Topoisomerase DNA/RNA Synthesis Proteasome Antibiotic Cancer
    Aclacinomycin A (Standard) is the analytical standard of Aclacinomycin A. This product is intended for research and analytical applications. Aclacinomycin A (Aclarubicin) is an orally active and potent anthracycline antitumor antibiotic. Aclacinomycin A is an inhibitor of topoisomerase I and II. Aclacinomycin A inhibits synthesis of nucleic acid, especially RNA. Aclacinomycin A might inhibit the 26S protease complex as well as the ubiquitin-ATP-dependent proteolysis .
    Aclacinomycin A (Standard)
  • HY-B0422R
    Nateglinide (Standard)

    A4166 (Standard); Senaglinide (Standard)

    		 Potassium Channel Dipeptidyl Peptidase Reference Standards Metabolic Disease
    Nateglinide (Standard) is the analytical standard of Nateglinide. This product is intended for research and analytical applications. Nateglinide, a D-phenylalanine derivative, is an orally active and short-acting insulinotropic agent and a DPP IV inhibitor. Nateglinide inhibits ATP-sensitive K + channels in pancreatic β-cells. Nateglinide is used for the treatment of type 2 (non-insulin-dependent) diabetes mellitus .
    Nateglinide (Standard)
  • HY-10336R
    Brivanib (alaninate) (Standard)

    BMS-582664 (Standard)

    		 Reference Standards VEGFR Autophagy Cancer
    Brivanib (alaninate) (Standard) is the analytical standard of Brivanib (alaninate). This product is intended for research and analytical applications. Brivanib alaninate (BMS-582664) is an ATP-competitive inhibitor against VEGFR2 with an IC50 of 25 nM; has moderate potency against VEGFR-1 and FGFR-1, but more than 240-fold against PDGFRβ .
    Brivanib (alaninate) (Standard)
  • HY-14881R
    Bedaquiline (Standard)

    TMC207 (Standard); R207910 (Standard)

    		 Reference Standards Bacterial Antibiotic Infection
    Bedaquiline (Standard) is the analytical standard of Bedaquiline. This product is intended for research and analytical applications. Bedaquiline (TMC207) is a diarylquinoline agent and inhibits Mycobacterium tuberculosis (Mtb) F1FO-ATP synthase through targeting of both the c- and the ε-subunit . Bedaquiline has uncoupler activity. Bedaquiline is used for the multi-agent resistant tuberculosis .
    Bedaquiline (Standard)
  • HY-12866AR
    Larotrectinib sulfate (Standard)

    		Trk Receptor Apoptosis Cancer
    Larotrectinib sulfate (Standard) is the analytical standard of Larotrectinib sulfate. This product is intended for research and analytical applications. Larotrectinib sulfate (LOXO-101 sulfate; ARRY-470 sulfate) is an ATP-competitive oral, selective inhibitor of the tropomyosin-related kinase (TRK) family receptors, with low nanomolar 50% inhibitory concentrations against all three isoforms (TRKA, B, and C).
    Larotrectinib sulfate (Standard)
  • HY-10195R
    Ruboxistaurin (Standard)

    LY333531 (Standard)

    		 Reference Standards PKC Metabolic Disease
    Ruboxistaurin (Standard) is the analytical standard of Ruboxistaurin. This product is intended for research and analytical applications. Ruboxistaurin (LY333531) is an orally active, selective PKC beta inhibitor (Ki=2 nM). Ruboxistaurin exhibits ATP dependent competitive inhibition of PKC beta I with an IC50 of 4.7 nM. Ruboxistaurin inhibits PKC beta II with an IC50 of 5.9 nM .
    Ruboxistaurin (Standard)
  • HY-W013636R
    2-Ketoglutaric acid (Standard)
    4 Publications Verification

    Alpha-Ketoglutaric acid (Standard); 2-Oxoglutaric acid (Standard)

    		 Reference Standards Tyrosinase Endogenous Metabolite Neurological Disease Metabolic Disease
    2-Ketoglutaric acid (Standard) (Alpha-Ketoglutaric acid (Standard)) is the analytical standard of 2-Ketoglutaric acid (HY-W013636). This product is intended for research and analytical applications. 2-Ketoglutaric acid (Alpha-Ketoglutaric acid) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC50=15 mM) .
    2-Ketoglutaric acid (Standard)
  • HY-W015883R
    Fumaric acid (Standard)

    		Reference Standards Endogenous Metabolite NF-κB p38 MAPK Metabolic Disease Inflammation/Immunology
    Fumaric acid (Standard) is the analytical standard of Fumaric acid. This product is intended for research and analytical applications. Fumaric acid is an unsaturated dicarbonic acid, an intermediate product of the citric acid cycle that provides intracellular energy in the form of ATP. Fumaric acid exerts anti-inflammatory effects by inhibiting the NF-κB signaling pathway dependent on p38 MAPK. Fumaric acid can be used in the study of pregnancy-induced hypertension .
    Fumaric acid (Standard)
  • HY-B0152AR
    Adenine hydrochloride (Standard)

    6-Aminopurine hydrochloride (Standard); Vitamin B4 hydrochloride (Standard)

    		 Reference Standards DNA/RNA Synthesis Endogenous Metabolite Cancer
    Adenine (hydrochloride) (Standard) is the analytical standard of Adenine (hydrochloride). This product is intended for research and analytical applications. Adenine hydrochloride (6-Aminopurine hydrochloride), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine hydrochloride acts as a chemical component of DNA and RNA. Adenine hydrochloride also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis[1][2][3].
    Adenine hydrochloride (Standard)

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