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Results for "

Adenosine Kinase

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Adenosine Kinase (9) Adenosine Receptor (3) AMPK (3) Antibiotic (4) Apoptosis (5) ATP Synthase (1) Aurora Kinase (1) Autophagy (2) Bacterial (2) CDK (2) Fungal (2) IRE1 (2) Isotope-Labeled Compounds (2) MMP (2) Nucleoside Antimetabolite/Analog (1) PARP (1) Phosphodiesterase (PDE) (2) PKA (4) Potassium Channel (1) Pyruvate Kinase (1) Ras (1) Salt-inducible Kinase (SIK) (1) Small Interfering RNA (siRNA) (3) TNF Receptor (2)
By Research Areas:	Cancer (10) Cardiovascular Disease (4) Infection (4) Inflammation/Immunology (10) Metabolic Disease (4) Neurological Disease (5)

By Targets:

Adenosine Kinase (9)

Adenosine Receptor (3)

AMPK (3)

Antibiotic (4)

Apoptosis (5)

ATP Synthase (1)

Aurora Kinase (1)

Autophagy (2)

Bacterial (2)

CDK (2)

Fungal (2)

IRE1 (2)

Isotope-Labeled Compounds (2)

MMP (2)

Nucleoside Antimetabolite/Analog (1)

PARP (1)

Phosphodiesterase (PDE) (2)

PKA (4)

Potassium Channel (1)

Pyruvate Kinase (1)

Ras (1)

Salt-inducible Kinase (SIK) (1)

Small Interfering RNA (siRNA) (3)

TNF Receptor (2)

By Research Areas:

Cancer (10)

Cardiovascular Disease (4)

Infection (4)

Inflammation/Immunology (10)

Metabolic Disease (4)

Neurological Disease (5)

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Targets Recommended: Adenosine Kinase Adenosine Receptor Adenosine Deaminase

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-164886

Adenosine Kinase siRNA-2	Small Interfering RNA (siRNA) Adenosine Kinase	Cardiovascular Disease
Adenosine Kinase siRNA-2 is a small interfering RNA that targets adenosine kinase messenger RNA.

HY-148189

Aldometanib 5 Publications Verification LXY-05-029	AMPK	Metabolic Disease
Aldometanib (LXY-05-029) is an orally active aldolase inhibitor. Aldometanib can activate lysosomal adenosine monophosphate-activated protein kinase (AMPK) and decreases blood glucose. Aldometanib can be used for the research of metabolic homeostasis .

HY-N7844

N6-Benzyladenosine BenzylAdenosine	Apoptosis Adenosine Receptor	Inflammation/Immunology Cancer
N6-Benzyladenosine is an adenosine receptor agonist, has a cytoactive activity. N6-Benzyladenosine arrests cell cycle at G0/G1 phase and induces cell apoptosis. N6-Benzyladenosine also exerts inhibitory effect on T. gondii adenosine kinase and glioma ^- .

HY-P1576A

AMARA peptide TFA	Salt-inducible Kinase (SIK) AMPK	Others
AMARA peptide (TFA) is a substrate for salt-inducible kinase (SIK) and adenosine monophosphate activated protein kinase (AMPK).

HY-103161

ABT-702 dihydrochloride 2 Publications Verification	Adenosine Kinase	Inflammation/Immunology
ABT-702 dihydrochloride is a potent **adenosine kinase (AK) inhibitor (IC₅₀**=1.7 nM).

HY-112482A

ABT-702 hydrochloride Adenosine Kinase Inhibitor hydrochloride	Adenosine Kinase	Inflammation/Immunology
ABT-702 hydrochloride is a potent inhibitor of **adenosine kinase with an IC₅₀** of 1.7 nM .

HY-164887

Adenosine Kinase siRNA-3	Small Interfering RNA (siRNA) Adenosine Kinase	Others
Adenosine Kinase siRNA-3 is a small interfering RNA (siRNA) targeting **Adenosine Kinase that has a knockdown effect on Adenosine Kinase**.

HY-164885

Adenosine Kinase siRNA-1	Small Interfering RNA (siRNA) Adenosine Kinase	Others
Adenosine Kinase siRNA-1 is a small interfering RNA (siRNA) targeting **Adenosine Kinase that has a knockdown effect on Adenosine Kinase**.

HY-19259

GP3269	Adenosine Kinase	Neurological Disease
GP3269 is a potent, selective, and orally active inhibitor of human adenosine kinase (AK) with an IC₅₀ of 11 nM. GP3269 exhibits anticonvulsant activity in rats .

HY-116005

A-286501	Adenosine Kinase	Neurological Disease Inflammation/Immunology
A-286501 is an orally active and potent carbocyclic nucleoside **adenosine kinase inhibitor with an IC₅₀** value of 0.47 nM, which shows analgesic and anti-inflammatory effects. A-286501 reduces nociception in animal models of acute (thermal), inflammatory (formalin and carrageenan) and neuropathic (L5/L6 nerve ligation and streptozotocin-induced diabetic) pain. A-286501 also reduces Carrageenan (HY-125474)-induced paw edema and myeloperoxidase activity in the injured paw. A-286501 is promising for research of analgesic and anti-inflammatory agents .

HY-N6631

7-Methoxyisoflavone 2 Publications Verification	AMPK	Metabolic Disease Cancer
7-Methoxyisoflavone is an isoflavone derivative and also an activator of adenosine monophosphate-activated protein kinase (AMPK).

HY-148327

AK-IN-1	Adenosine Kinase	Cardiovascular Disease Neurological Disease Inflammation/Immunology
AK-IN-1 (compound 4072-2732) is an **adenosine kinase** (AK) inhibitor that is competitive for adenosine (Ado) but not for ATP. AK-IN-1 inhibits 86%, 87% and 89% of AK activity at concentrations of 2, 4 and 10 µM, respectively. AK-IN-1 has good potential for research in many disease areas, including ischaemia, inflammation and seizures .

HY-134283

8-Benzylthio-cAMP	PKA Apoptosis	Others
8-Benzylthio-cAMP is a derivative of cyclic adenosine monophosphate (cAMP). 8-Bn-cAMP is a site-selective activator of cAMP-dependent protein kinases. Compared with cyclic adenosine monophosphate, it is more stable to phosphodiesterase (PDE) hydrolysis and has higher membrane permeability. 8-Bn-cAMP can be used to study the role of cAMP in regulating cell proliferation, differentiation and apoptosis .

HY-15424

5-Iodotubercidin 5+ Cited Publications NSC 113939; 5-ITu	Adenosine Kinase	Cancer
5-Iodotubercidin (NSC 113939), an ATP mimetic, is a potent **adenosine kinase inhibitor with an IC₅₀** of 26 nM. 5-Iodotubercidin (NSC 113939) initiates glycogen synthesis in isolated hepatocytes by causing inactivation of phosphorylase and activation of glycogen synthase. 5-Iodotubercidin (NSC 113939) also inhibits CK1, insulin receptor tyrosine kinase, phosphorylase kinase, PKA, CK2, PKC and Haspin .

HY-110124

ML202	Pyruvate Kinase	Cancer
ML202 is a highly specific allosteric activator of human pyruvate kinase M2 (hPK-M2), which can affect the cooperativity of phosphoenolpyruvate (PEP) binding, while adenosine diphosphate (ADP) binding almost no effect .

HY-B0764G

Bucladesine Dibutyryl cAMP; DBcAMP	PKA Phosphodiesterase (PDE)	Neurological Disease Inflammation/Immunology
Bucladesine (Dibutyryl cAMP) (GMP) is a Bucladesine (HY-B0764B) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Bucladesine is a membrane permeable selective activator that activates cyclic adenosine phosphate dependent protein kinase A (PKA) .

HY-N0262

Cordycepin 10+ Cited Publications 3'-DeoxyAdenosine	TNF Receptor MMP Bacterial Autophagy Antibiotic	Infection Inflammation/Immunology Cancer
Cordycepin (3'-Deoxyadenosine) is a nucleoside derivative and inhibits IL-1β-induced MMP-1 and MMP-3 expression in rheumatoid arthritis synovial fibroblasts (RASFs) in a dose-dependent manner . Cordycepin kills *Mycobacterium tuberculosis* through hijacking the bacterial adenosine kinase .

HY-N7844S

N6-Benzyladenosine-d5 BenzylAdenosine-d₅	Isotope-Labeled Compounds Apoptosis Adenosine Receptor	Inflammation/Immunology Cancer
N6-Benzyladenosine-d₅ (Benzyladenosine-d₅) is deuterium labeled N6-Benzyladenosine. N6-Benzyladenosine is an adenosine receptor agonist, has a cytoactive activity. N6-Benzyladenosine arrests cell cycle at G0/G1 phase and induces cell apoptosis. N6-Benzyladenosine also exerts inhibitory effect on T. gondii adenosine kinase and glioma .

HY-134263

8-Br-cAMP-AM	PKA Ras	Cardiovascular Disease
8-Br-cAMP-AM is a cyclic adenosine monophosphate (cAMP) analog that activates two major signal transduction pathways in the heart by mimicking the effects of cAMP: protein kinase A (PKA) and guanosine nucleotide exchange factor (Epac), which is directly activated by cAMP. 8-Br-cAMP-AM can be used to study cardiac ischemia and reperfusion injury .

HY-N0262R

Cordycepin (Standard)	TNF Receptor MMP Bacterial Autophagy Antibiotic	Infection Inflammation/Immunology Cancer
Cordycepin (Standard) is the analytical standard of Cordycepin. This product is intended for research and analytical applications. Cordycepin (3'-Deoxyadenosine) is a nucleoside derivative and inhibits IL-1β-induced MMP-1 and MMP-3 expression in rheumatoid arthritis synovial fibroblasts (RASFs) in a dose-dependent manner . Cordycepin kills Mycobacterium tuberculosis through hijacking the bacterial adenosine kinase .

HY-137381

6-Bnz-cAMP N6-Benzoyl-cAMP	Potassium Channel	Others
6-Bnz-cAMP (N6-Benzoyl-cAMP), a derivative of cyclic adenosine monophosphate (cAMP), is a potent inhibitor of the bTREK-1 potassium channel. 6-Bnz-cAMP can strongly inhibit the bTREK-1 potassium channel through a protein kinase A (PKA) independent mechanism. 6-Bnz-cAMP can be used to explore potential signal transduction proteins in the cAMP signaling pathway .

HY-108047

MK-0873	Phosphodiesterase (PDE)	Metabolic Disease Inflammation/Immunology
MK-0873 is a selective phosphodiesterase-4 (PDE4) inhibitor. MK-0873 increases intracellular levels of cyclic adenosine phosphate (cAMP) by inhibiting the activity of the PDE4 enzyme and subsequently activates protein kinase A (PKA). Activated PKA inhibits the activity of inflammatory cells and leads to direct relaxation of airway smooth muscle. MK-0873 can be used in studies of chronic obstructive pulmonary disease (COPD) .

HY-10250S1

Triciribine phosphate-d3 TCN-P-d₃	Isotope-Labeled Compounds ATP Synthase	Metabolic Disease
Triciribine phosphate-d3 (TCN-P-d3) is a deuterated compound of Triciribine phosphate (TCN-P). TCN-P inhibits adenosine monophosphate (AMP)-activated protein kinase through an allosteric mechanism, affecting the first key step in de novo purine biosynthesis. Triciribine phosphate also inhibits inosine monophosphate dehydrogenase, which is the first key step in guanosine nucleotide synthesis. Triciribine phosphate does not affect ligase activity .

HY-23789

2′-O-(2-Methoxyethyl)guanosine 2'-O-MOE-rG	Nucleoside Antimetabolite/Analog	Others
2′-O-(2-Methoxyethyl)guanosine (2'-O-MOE-rG), a 2′-O-methoxyethyl-modified nucleoside, can be produced by enzymatic conversion (adenosine deaminase) from 2′-O-(2-methoxyethyl)-2,6-diaminopurine riboside. 2′-O-(2-Methoxyethyl)guanosine neither effectively phosphorylated by cytosolic nucleoside kinases, nor are they incorporated into cellular DNA or RNA .

HY-115862

Benzo[c][1,8]naphthyridin-6(5H)-one	Adenosine Receptor PARP Aurora Kinase	Cardiovascular Disease Cancer
Benzo[c][1,8]naphthyridin-6(5H)-one exhibits low micromolar affinity to human adenosine receptor (AR) A₁ and hA_2A, with K_i of 4.6 and 4.8 μM. Benzo[c][1,8]naphthyridin-6(5H)-one is inhibitor for poly ADP-ribose polymerase-1 (PARP-1) and aurora kinase A, with IC₅₀ of 0.311 and 5.5 μM .

HY-B0764B

Bucladesine Dibutyryl cAMP; DBcAMP	PKA	Neurological Disease
Bucladesine (DBcAMP) is a membrane permeable selective activator that activates cyclic adenosine phosphate dependent protein kinase A (PKA). The main regulatory mechanism of Bucladesine involves the cAMP/PKA signaling pathway. When Bucladesine activates PKA, it can promote a variety of cellular processes, including neurodevelopment, growth and plasticity. In particular, the cAMP/PKA signaling pathway plays a key role in the expression of long-term enhancement (LTP) and long-term inhibition (LTD), as well as in the formation of long-term memory in the hippocampus. Bucladesine can be used to study memory formation and neuroplasticity .

HY-103248

Toyocamycin 5+ Cited Publications Vengicide	IRE1 Fungal Antibiotic Apoptosis CDK	Infection Cancer
Toyocamycin (Vengicide) is an adenosine analog produced by Streptomyces diastatochromogenes, acts as an XBP1 inhibitor. Toyocamycin blocks RNA synthesis and ribosome function, and induces apoptosis. Toyocamycin affects IRE1α-XBP1 pathway, and inhibits XBP1 mRNA cleavage with an IC₅₀ value of 80 nM with affecting IRE1α auto-phosphorylation. Toyocamycin specifically inhibits CDK9 with an IC₅₀ value of 79 nM .

HY-103248R

Toyocamycin (Standard)	IRE1 Fungal Antibiotic Apoptosis CDK	Infection Cancer
DL-Aspartic acid (Standard) is the analytical standard of DL-Aspartic acid. This product is intended for research and analytical applications. DL-Aspartic acid (DL-Asp-OH) is a kind of biological materials or organic compounds that are widely used in life science research .

Cat. No.	Product Name	Type

HY-23789

2′-O-(2-Methoxyethyl)guanosine 2'-O-MOE-rG	Gene Sequencing and Synthesis
2′-O-(2-Methoxyethyl)guanosine (2'-O-MOE-rG), a 2′-O-methoxyethyl-modified nucleoside, can be produced by enzymatic conversion (adenosine deaminase) from 2′-O-(2-methoxyethyl)-2,6-diaminopurine riboside. 2′-O-(2-Methoxyethyl)guanosine neither effectively phosphorylated by cytosolic nucleoside kinases, nor are they incorporated into cellular DNA or RNA .

AMARA peptide TFA	Salt-inducible Kinase (SIK) AMPK	Others
AMARA peptide (TFA) is a substrate for salt-inducible kinase (SIK) and adenosine monophosphate activated protein kinase (AMPK).

(Trp4)-Kemptide	Peptides	Others
(Trp4)-Kemptide is a peptide substrate for adenosine 3',5'-cyclic monophosphate-dependent protein kinase .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N7844

N6-Benzyladenosine BenzylAdenosine	Natural Products Classification of Application Fields Eupatorium buniifolium Hook. & Arn. Source classification Umbelliferae Plants Phytohormone Inflammation/Immunology Disease Research Fields Cytokinin Cancer Agricultural Research	Apoptosis Adenosine Receptor
N6-Benzyladenosine is an adenosine receptor agonist, has a cytoactive activity. N6-Benzyladenosine arrests cell cycle at G0/G1 phase and induces cell apoptosis. N6-Benzyladenosine also exerts inhibitory effect on T. gondii adenosine kinase and glioma ^- .

HY-N0262

Cordycepin 10+ Cited Publications 3'-DeoxyAdenosine	Infection Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Inflammation/Immunology Disease Research Fields Cancer	TNF Receptor MMP Bacterial Autophagy Antibiotic
Cordycepin (3'-Deoxyadenosine) is a nucleoside derivative and inhibits IL-1β-induced MMP-1 and MMP-3 expression in rheumatoid arthritis synovial fibroblasts (RASFs) in a dose-dependent manner . Cordycepin kills *Mycobacterium tuberculosis* through hijacking the bacterial adenosine kinase .

HY-103248

Toyocamycin 5+ Cited Publications Vengicide	Infection Structural Classification Microorganisms Classification of Application Fields Antibiotics Source classification Antibacterial Disease Research Disease Research Fields Other Antibiotics	IRE1 Fungal Antibiotic Apoptosis CDK
Toyocamycin (Vengicide) is an adenosine analog produced by Streptomyces diastatochromogenes, acts as an XBP1 inhibitor. Toyocamycin blocks RNA synthesis and ribosome function, and induces apoptosis. Toyocamycin affects IRE1α-XBP1 pathway, and inhibits XBP1 mRNA cleavage with an IC₅₀ value of 80 nM with affecting IRE1α auto-phosphorylation. Toyocamycin specifically inhibits CDK9 with an IC₅₀ value of 79 nM .

HY-N0262R

Cordycepin (Standard)	Structural Classification Natural Products Microorganisms Source classification	TNF Receptor MMP Bacterial Autophagy Antibiotic
Cordycepin (Standard) is the analytical standard of Cordycepin. This product is intended for research and analytical applications. Cordycepin (3'-Deoxyadenosine) is a nucleoside derivative and inhibits IL-1β-induced MMP-1 and MMP-3 expression in rheumatoid arthritis synovial fibroblasts (RASFs) in a dose-dependent manner . Cordycepin kills Mycobacterium tuberculosis through hijacking the bacterial adenosine kinase .

HY-103248R

Toyocamycin (Standard)	Structural Classification Microorganisms Antibiotics Source classification Antibacterial Disease Research Other Antibiotics	IRE1 Fungal Antibiotic Apoptosis CDK
DL-Aspartic acid (Standard) is the analytical standard of DL-Aspartic acid. This product is intended for research and analytical applications. DL-Aspartic acid (DL-Asp-OH) is a kind of biological materials or organic compounds that are widely used in life science research .

Species:	Human (4)
Tag:	His (2) Tag Free (2) GST (1)
Source:	HEK293 (1) Sf9 insect cells (1) E. coli (2)

Cat. No.	Compare	Product Name	Species	Source

HY-P75530

	*ADK/Adenosine* Kinase Protein, Human (HEK293)** Adenosine Kinase; AK; Adenosine 5'-phosphotransferase; ADK	Human	HEK293
	ADK is an enzyme that catalyzes the transfer of gamma-phosphate from adenosine triphosphate (ATP) to adenosine (Ado) to form adenosine monophosphate (AMP). ADK acts as a potential regulator of extracellular adenosine and intracellular adenine nucleotide concentrations. ADK is a therapeutic target for controlling obesity and non-alcoholic fatty liver disease. ADK/Adenosine Kinase Protein, Human (HEK293) is the recombinant human-derived ADK/Adenosine Kinase protein, expressed by HEK293 , with tag free. The total length of ADK/Adenosine Kinase Protein, Human (HEK293) is 345 a.a., with molecular weight of ~38.74 kDa.

HY-P75529

	*ADK/Adenosine* Kinase Protein, Human (sf9, His-GST)** Adenosine Kinase; AK; Adenosine 5'-phosphotransferase; ADK	Human	Sf9 insect cells
	ADK is an enzyme that catalyzes the transfer of gamma-phosphate from adenosine triphosphate (ATP) to adenosine (Ado) to form adenosine monophosphate (AMP). ADK acts as a potential regulator of extracellular adenosine and intracellular adenine nucleotide concentrations. ADK is a therapeutic target for controlling obesity and non-alcoholic fatty liver disease. ADK/Adenosine Kinase Protein, Human (sf9, His-GST) is the recombinant human-derived ADK/Adenosine Kinase protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag. The total length of ADK/Adenosine Kinase Protein, Human (sf9, His-GST) is 345 a.a., with molecular weight of ~60 kDa.

HY-P701966

	PKCi Protein, Human (H114A) HINT1; Adenosine 5'-monophosphoramidase HINT1; Desumoylating isopeptidase HINT1; Histidine triad nucleotide-binding protein 1; Protein Kinase C inhibitor 1; Protein Kinase C-interacting protein 1; PKCI-1	Human	E. coli
	PKCi protein has adenosine 5'-monophosphate amidase activity and can hydrolyze compounds such as AMP-NH2. It also acts on AMP-morpholidate, GMP-morpholidate, lysyl-AMP, Met-AMP, His-AMP, Asp-AMP, lysyl-GMP and AMP-N-alanine methyl ester. PKCi Protein, Human (H114A) is the recombinant human-derived PKCi protein, expressed by E. coli , with tag free.

HY-P701967

	PKCi Protein, Human (H114A, His) HINT1; Adenosine 5'-monophosphoramidase HINT1; Desumoylating isopeptidase HINT1; Histidine triad nucleotide-binding protein 1; Protein Kinase C inhibitor 1; Protein Kinase C-interacting protein 1; PKCI-1	Human	E. coli
	PKCi protein has adenosine 5'-monophosphate amidase activity and can hydrolyze compounds such as AMP-NH2. It also acts on AMP-morpholidate, GMP-morpholidate, lysyl-AMP, Met-AMP, His-AMP, Asp-AMP, lysyl-GMP and AMP-N-alanine methyl ester. PKCi Protein, Human (H114A, His) is the recombinant human-derived PKCi protein, expressed by E. coli , with N-6*His labeled tag.

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Cat. No.	Product Name	Chemical Structure

HY-N7844S

N6-Benzyladenosine-d5
N6-Benzyladenosine-d₅ (Benzyladenosine-d₅) is deuterium labeled N6-Benzyladenosine. N6-Benzyladenosine is an adenosine receptor agonist, has a cytoactive activity. N6-Benzyladenosine arrests cell cycle at G0/G1 phase and induces cell apoptosis. N6-Benzyladenosine also exerts inhibitory effect on T. gondii adenosine kinase and glioma .

HY-10250S1

Triciribine phosphate-d3

Triciribine phosphate-d3 (TCN-P-d3) is a deuterated compound of Triciribine phosphate (TCN-P). TCN-P inhibits adenosine monophosphate (AMP)-activated protein kinase through an allosteric mechanism, affecting the first key step in de novo purine biosynthesis. Triciribine phosphate also inhibits inosine monophosphate dehydrogenase, which is the first key step in guanosine nucleotide synthesis. Triciribine phosphate does not affect ligase activity .

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P83238

	HINT1 Antibody (YA2983) HINT1; HINT; PKCI1; PRKCNH1; Histidine triad nucleotide-binding protein 1; Adenosine 5'-monophosphoramidase; Protein Kinase C inhibitor 1; Protein Kinase C-interacting protein 1; PKCI-1	WB, ICC/IF, IP	Human
	HINT1 Antibody (YA2983) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2983), targeting HINT1, with a predicted molecular weight of 14 kDa (observed band size: 14 kDa). HINT1 Antibody (YA2983) can be used for WB, ICC/IF, IP experiment in human background.

HY-P82944

	ADK Antibody (YA2689) ADK; Adenosine Kinase; AK; Adenosine 5'-phosphotransferase	WB, IHC-P	Human, Mouse, Rat
	ADK Antibody (YA2689) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2689), targeting ADK, with a predicted molecular weight of 41 kDa (observed band size: 41 kDa). ADK Antibody (YA2689) can be used for WB, IHC-P experiment in human, mouse, rat background.