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Results for "

B12

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Cytotoxin (1) Apoptosis (1) Biochemical Assay Reagents (3) Cytochrome P450 (1) Endogenous Metabolite (25) Fungal (1) GABA Receptor (1) Influenza Virus (1) Interleukin Related (1) Isotope-Labeled Compounds (1) JNK (1) Phosphoglycerate Dehydrogenase (PHGDH) (1) RAR/RXR (1) Small Interfering RNA (siRNA) (1) Toll-like Receptor (TLR) (1)
By Research Areas:	Cancer (12) Infection (3) Inflammation/Immunology (5) Metabolic Disease (19) Neurological Disease (4)
Oligonucleotides:	Pre-designed siRNA Sets (1) siRNAs (1)

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Fluorescent Dye

Biochemical Assay Reagents

MCE Kits

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B0315

Vitamin B12 2 Publications Verification Cyanocobalamin	Endogenous Metabolite	Metabolic Disease Inflammation/Immunology Cancer
Vitamin B12 is a vitamin. Vitamin B12 plays a key role in the normal functioning of the brain and nervous system, and for the formation of blood. Vitamin B12 is beneficial for many inflammatory diseases and also provides protection in oxidative-stress-associated pathologies .

HY-112790

Adenosylcobalamin Coenzyme B12; Cobamamide; AdoCbl	Endogenous Metabolite	Metabolic Disease
Adenosylcobalamin (Coenzyme B12;Cobamamide;AdoCbl) is an active form of Vitamin B₁₂ which is a cofactor for methylmalonyl CoA mutase

HY-B2209

Hydroxocobalamin 2 Publications Verification Vitamin B12a	Endogenous Metabolite	Metabolic Disease
Hydroxocobalamin (Vitamin B12a) is an injectable naturally occurring form of vitamin B12 with a favorable adverse effect profile, used as a dietary supplement in the treatment of vitamin B12 deficiency including pernicious anemia .

HY-B0586

Methylcobalamin 1 Publications Verification Mecobalamin; CH3-B12	Endogenous Metabolite	Metabolic Disease
Methylcobalamin (CH3-B12), a cobalamin, is a form of vitamin B12.

HY-B0315S

*Vitamin B12-13C7*	Endogenous Metabolite	Metabolic Disease
Vitamin B12- ¹³C₇ is the ¹³C-labeled Vitamin B12. Vitamin B12 is a vitamin. Vitamin B12 plays a key role in the normal functioning of the brain and nervous system, and for the formation of blood[1][2].

HY-B2209B

Hydroxocobalamin acetate 2 Publications Verification Vitamin B12a acetate	Endogenous Metabolite	Metabolic Disease
Hydroxocobalamin acetate is an injectable naturally occurring form of vitamin B12 with a favorable adverse effect profile, used as a dietary supplement in the research of vitamin B12 deficiency including pernicious anemia .

HY-B2209A

Hydroxocobalamin monohydrochloride 2 Publications Verification Vitamin B12a monohydrochloride	Endogenous Metabolite	Metabolic Disease
Hydroxocobalamin monohydrochloride (Vitamin B12a monohydrochloride) is an injectable naturally occurring form of vitamin B12 with a favorable adverse effect profile, used as a dietary supplement in the treatment of vitamin B12 deficiency including pernicious anemia .

HY-B0315R

*Vitamin B12* (Standard)**	Endogenous Metabolite	Metabolic Disease Cancer
Vitamin B12 (Standard) is the analytical standard of Vitamin B12. This product is intended for research and analytical applications. Vitamin B12 is a vitamin. Vitamin B12 plays a key role in the normal functioning of the brain and nervous system, and for the formation of blood .

HY-B0315A

Biotin-Vitamin B12	Endogenous Metabolite	Metabolic Disease
Biotin-Vitamin B12 is the biotinylated Vitamin B12. Vitamin B12 is a vitamin that plays a key role in the normal functioning of the brain and nervous system, and for the formation of blood .

HY-B0315B

*Vitamin B12* hydrate** Cyanocobalamin hydrate	Endogenous Metabolite	Metabolic Disease Inflammation/Immunology Cancer
Vitamin B12 (Cyanocobalamin) hydrate is a vitamin. Vitamin B12 plays a key role in the normal functioning of the brain and nervous system, and for the formation of blood. Vitamin B12 hydrate is beneficial for many inflammatory diseases and also provides protection in oxidative-stress-associated pathologies .

HY-B2209R

Hydroxocobalamin (Standard)	Endogenous Metabolite	Metabolic Disease
Hydroxocobalamin (Standard) is the analytical standard of Hydroxocobalamin. This product is intended for research and analytical applications. Hydroxocobalamin (Vitamin B12a) is an injectable naturally occurring form of vitamin B12 with a favorable adverse effect profile, used as a dietary supplement in the treatment of vitamin B12 deficiency including pernicious anemia .

HY-B2209BR

Hydroxocobalamin acetate (Standard) Vitamin B12a acetate (Standard)	Endogenous Metabolite	Metabolic Disease
Hydroxocobalamin (acetate) (Standard) is the analytical standard of Hydroxocobalamin (acetate). This product is intended for research and analytical applications. Hydroxocobalamin acetate is an injectable naturally occurring form of vitamin B12 with a favorable adverse effect profile, used as a dietary supplement in the research of vitamin B12 deficiency including pernicious anemia .

HY-113092

Propionylcarnitine	Endogenous Metabolite	Metabolic Disease
Propionylcarnitine is metabolized by carnitine acetyltransferase from propionyl-CoA. Increased propionylcarnitine is regarded as a biomarker of vitamin B12 deficiency .

HY-139036

Dicyanocobinamide	Biochemical Assay Reagents	Others
Dicyanocobinamide is a precursor to vitamin B12. Dicyanocobinamide is a catalyst for the oxidation of peptides, which is utilized for a rapid, environmentally friendly method of disulfide bond formation in water. Dicyanocobinamide exhibits good biocompatibility .

HY-D1056A4

Lipopolysaccharides, from E. coli O128:B12 LPS, from Escherichia coli (O128:B12)	Toll-like Receptor (TLR)	Inflammation/Immunology
Lipopolysaccharides, from E. coli O128:B12 is commonly used to stimulate the inflammatory pathway in an infection/inflammation induced preterm animal model. Specific Lipopolysaccharides from E. coli serotypes induce activation of different inflammatory pathways in the neonatal rat brain. Compared with other Escherichia coli, Lipopolysaccharides (O111:B4, O55:B5, O127:B8), Lipopolysaccharides, from E. coli O128:B12 has lower induction efficiency of inflammation. Cub survival rate was 100% after the treatment .

HY-B0586R

Methylcobalamin (Standard)	Endogenous Metabolite	Metabolic Disease
Methylcobalamin (Standard) is the analytical standard of Methylcobalamin. This product is intended for research and analytical applications. Methylcobalamin (CH3-B12), a cobalamin, is a form of vitamin B12.

HY-103395

Methylmalonic acid 1 Publications Verification Methylpropanedioic acid; Methylmalonate	Endogenous Metabolite	Cancer
Methylmalonic acid (Methylmalonate) is an indicator of Vitamin B-12 deficiency in cancer.

HY-112790R

Adenosylcobalamin (Standard)	Endogenous Metabolite	Metabolic Disease
Adenosylcobalamin (Standard) is the analytical standard of Adenosylcobalamin. This product is intended for research and analytical applications. Adenosylcobalamin (Coenzyme B12;Cobamamide;AdoCbl) is an active form of Vitamin B₁₂ which is a cofactor for methylmalonyl CoA mutase

HY-W040821

DL-Homocysteine 2 Publications Verification	Endogenous Metabolite	Neurological Disease
DL-Homocysteine is a weak neurotoxin, and can affect the production of kynurenic acid in the brain. DL-Homocysteine is correlated with Vitamin B12, renal functions and folate levels, affects the cross-sectional cognition indirectly through white matter microstructural integrity .

HY-166857

DMPE-PEG-amine TFA (MW 2000)	Biochemical Assay Reagents	Others
B12&" is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. "&B12&"can be used in drug delivery research ."

HY-B2209AR

Hydroxocobalamin monohydrochloride (Standard)	Endogenous Metabolite	Metabolic Disease
Hydroxocobalamin (monohydrochloride) (Standard) is the analytical standard of Hydroxocobalamin (monohydrochloride). This product is intended for research and analytical applications. Hydroxocobalamin monohydrochloride (Vitamin B12a monohydrochloride) is an injectable naturally occurring form of vitamin B12 with a favorable adverse effect profile, used as a dietary supplement in the treatment of vitamin B12 deficiency including pernicious anemia .

HY-103395R

Methylmalonic acid (Standard) Methylpropanedioic acid (Standard); Methylmalonate (Standard)	Endogenous Metabolite	Cancer
Methylmalonic acid (Standard) is the analytical standard of Methylmalonic acid. This product is intended for research and analytical applications. Methylmalonic acid (Methylmalonate) is an indicator of Vitamin B-12 deficiency in cancer.

HY-113045

Aquacobalamin	Endogenous Metabolite	Metabolic Disease
Aquacobalamin is one of the major forms of vitamin B12 isolated from mammalian cells. Aquacobalamin accelerates the oxidation of azo-dye Orange II (HY-N1442) by HSO₅ ^- in aqueous solutions. Aquacobalamin binds hydrogen peroxide reversibly to form a cobalt(III) hydroperoxo adduct with a 0.25 mM dissociation constant .

HY-133739

NBD-125	RAR/RXR	Cancer
NBD-125 (B-12), a berberine analogue, is an RXRα activator, with an IC₅₀ of 31.10 μM in KM12C cell .

HY-103395S

Methylmalonic acid-d3 Methylpropanedioic acid-d₃; Methylmalonate-d₃	Endogenous Metabolite	Cancer
Methylmalonic acid-d₃ is the deuterium labeled Methylmalonic acid. Methylmalonic acid (Methylmalonate) is an indicator of Vitamin B-12 deficiency in cancer[1][2].

HY-103395S1

Methylmalonic acid-13C4	Endogenous Metabolite	Cancer
Methylmalonic acid- ¹³C₄ is the ¹³C labeled Methylmalonic acid[1]. Methylmalonic acid (Methylmalonate) is an indicator of Vitamin B-12 deficiency in cancer[2].

HY-N13061

Nervon	Others	Neurological Disease
Nervon is a crystalline cerebroside. Nervon can be used for the research of peripheral neuropathies and megaloblastic anemia caused by vitamin B12 deficiency .

HY-17016S

Oseltamivir-d5 phosphate GS 4104-d₅ phosphate	Isotope-Labeled Compounds Influenza Virus	Infection
Oseltamivir-d₅ (phosphate) is the deuterium labeled Oseltamivir phosphate. Oseltamivir phosphate (GS 4104) is a neuraminidase inhibitor recommended for the treatment and prophylaxis of influenza A and B[1][2].

HY-137808

Succinyl-Coenzyme A sodium Succinyl-CoA sodium	Endogenous Metabolite	Neurological Disease Metabolic Disease
Succinyl-Coenzyme A (Succinyl-CoA) sodium is an intermediate of the citric acid cycle. Succinyl-Coenzyme A sodium can be converted to succinic acid and can also combines with glycine to form δ-ALA to synthesize porphyrins (heme). Succinyl-Coenzyme A sodium can be used in the study of metabolic, neurological and haematological abnormalities (such as porphyrias) caused by nutritional vitamin B₁₂ deficiency (resulting in a deficiency in Succinyl-Coenzyme A synthesis) .

HY-154992

2,4-Difluorophenylethynylcobalamin F2PhEtyCbl	Others	Others
2,4-Difluorophenylethynylcobalamin is a potential *B12* antivitamin via binding to human B12 -processing enzyme CblC with high affinity (KD=130 nm). 2,4-Difluorophenylethynylcobalamin withstood tailoring by CblC, and stabilizes the ternary complex with the cosubstrate glutathione (GSH) . 2,4-Difluorophenylethynylcobalamin is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-156796

Akt/ROCK-IN-1	ADC Cytotoxin	Neurological Disease Cancer
Akt/ROCK-IN-1 (B12) is a dual inhibitor for Akt and ROCK, with the IC₅₀s of 0.023 nM and 1.47 nM, respectively. Akt/ROCK-IN-1 has antitumor activity for neuroblastoma .

HY-149615

Antibacterial agent 157	Fungal	Infection
Antibacterial agent 157 (compound B12) is a fungicidal agent. Antibacterial agent 157 can influence the protein synthesis of Botrytis cinerea. Antibacterial agent 157 can be used for gray mold resistance control research .

HY-126791

Methylmalonyl-CoA Isosuccinyl coenzyme A; Methylmalonyl coenzyme A	Endogenous Metabolite	Others
Methylmalonyl coenzyme A (Methylmalonyl-CoA) is a catabolite of valine, isoleucine, methionine, threonine, odd-chain fatty acids, and cholesterol. Methylmalonyl coenzyme A tetralithium is converted to succinyl-CoA by enzymatic reaction of methylmalonyl-CoA mutase (MCM) with coenzyme vitamin B12 .

HY-126791A

Methylmalonyl-CoA tetralithium Isosuccinyl coenzyme A tetralithium; Methylmalonyl coenzyme tetralithium	Endogenous Metabolite	Others
Methylmalonyl-CoA (Methylmalonyl coenzyme A) tetralithium is a catabolite of valine, isoleucine, methionine, threonine, odd-chain fatty acids, and cholesterol. Methylmalonyl-CoA tetralithium is converted to succinyl-CoA by enzymatic reaction of methylmalonyl-CoA mutase (MCM) with coenzyme vitamin B12 .

HY-W127737

Methylcobalamin hydrate Mecobalamin hydrate	Biochemical Assay Reagents	Others
Methylcobalamin Hydrate is a coenzyme required for methionine biosynthesis. Vitamins (hematopoiesis). It acts as a histamine receptor, Alzheimer study. Methylcobalamin is also used in the research of peripheral neuropathy, diabetic neuropathy, and as an initial research for amyotrophic lateral sclerosis. It can be used to prevent or research pathologies caused by vitamin B12 deficiency, such as pernicious anemia.

HY-161456

PHGDH-IN-5	Phosphoglycerate Dehydrogenase (PHGDH)	Cancer
PHGDH-IN-5 (Compound B12) is a covalen inhibitor of PHGDH with an IC₅₀ value of 0.29 μM. PHGDH-IN-5 can inhibit cell proliferation in cancer cell lines overexpressing PHGDH. PHGDH-IN-5 can reduce the production of serine derived from glucose in MDA-MB-468 cells .

HY-115980

Anticancer agent 39	Apoptosis	Cancer
Anticancer agent 39 (compound B12), a fluorescent derivative of Jiyuan Oridonin A (JOA), induces the collapse of mitochondrial membrane potential (MMP)and thus induced apoptosis.Anticancer agent 39 inhibits cell cloning and migration.Anticancer agent 39 exhibits promising anti-proliferative activity against HGC-27 cells with IC₅₀ value of 0.39 μM .

HY-144761

TOPK-p38/JNK-IN-1	JNK	Cancer
TOPK-p38/JNK-IN-1 (Compound B12) is an orally active TOPK-p38/JNK signaling pathway inhibitor with the IC₅₀ value of 2.14 µM for NO production. TOPK-p38/JNK-IN-1 shows anti-inflammatory activities. TOPK-p38/JNK-IN-1 also inhibits phosphorylate downstream related proteins and avoids degradation of TOPK .

HY-137936

Terrecyclic Acid	Others	Infection
Terrecyclic acid is a sesquiterpene originally isolated from A. terreus with antibiotic and anticancer activity. It is active against S. aureus, B. subtilis, and M. roseus (MICs=25, 50, and 25 μg/mL, respectively). Terrecyclic acid induces a heat shock response, increases levels of reactive oxygen species (ROS), and inhibits NF-κB activity and cell growth in 3T3-Y9-B12 cells.2 In vivo, terrecyclic acid (0.1, 1, and 10 mg/ml) reduces the number of ascitic fluid tumor cells in a mouse model of P388 murine leukemia.

HY-RS06392

HSD17B12 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
HSD17B12 Human Pre-designed siRNA Set A contains three designed siRNAs for HSD17B12 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HSD17B12 Human Pre-designed siRNA Set A HSD17B12 Human Pre-designed siRNA Set A

HY-137007

SMA-12b	Interleukin Related	Others Inflammation/Immunology
SMA-12b is a small molecule analogue of the parasitic worm compound ES-62. SMA-12b has immunomodulatory activity, acting by regulating the expression of multiple inflammatory response genes, especially those associated with inflammatory bodies. SMA-12b significantly reduces the expression of cytokine IL-1β associated with inflammatory bodies and inhibites the production of IL-1β through a mechanism mediated by NRF2. SMA-12b can be used in the study of rheumatoid arthritis (RA) and other autoimmune diseases .

HY-B0822S1

Fipronil-13C6	GABA Receptor Cytochrome P450	Inflammation/Immunology
Fipronil- ¹³C₆ is the ¹³C-labeled Fipronil. Fipronil is an insecticide that acts as a selective antagonist of insect GABA receptors (IC50s = 30 nM and 1,600 nM for cockroach and rat receptors, respectively). Fipronil also inhibits desensitizing and non-desensitizing glutamate-induced chloride currents in cockroach neurons (IC50s = 800 nM and 10 nM, respectively). Fipronil induces activity of the cytochrome P450 (CYP) isoforms CYP1A1/2, CYP2B1/2, and CYP3A1/2 in isolated rat liver microsomes.

Cat. No.	Product Name	Type

HY-B0315A

Biotin-Vitamin B12	Fluorescent Dyes/Probes
Biotin-Vitamin B12 is the biotinylated Vitamin B12. Vitamin B12 is a vitamin that plays a key role in the normal functioning of the brain and nervous system, and for the formation of blood .

Cat. No.	Product Name	Type

HY-130777A

AMP-PNP lithium hydrate 1 Publications Verification Adenylyl imidodiphosphate lithium hydrate	Gene Sequencing and Synthesis
AMP-PNP lithium hydrate is a non-hydrolyzable analog of ATP. AMP-PNP can replace ATP for biological research and is not hydrolyzed by intracellular enzymes. In the study of BtuCD-F, a vitamin B12 transporter, it was found that AMP-PNP can block the channel formed by the two BtuCDs of the BtuCD-F complex, thereby preventing the entry of vitamin B12 .

HY-D1056A4

Lipopolysaccharides, from E. coli O128:B12

LPS, from Escherichia coli (O128:B12)

Carbohydrates

Lipopolysaccharides, from E. coli O128:B12 is commonly used to stimulate the inflammatory pathway in an infection/inflammation induced preterm animal model. Specific Lipopolysaccharides from E. coli serotypes induce activation of different inflammatory pathways in the neonatal rat brain. Compared with other Escherichia coli, Lipopolysaccharides (O111:B4, O55:B5, O127:B8), Lipopolysaccharides, from E. coli O128:B12 has lower induction efficiency of inflammation. Cub survival rate was 100% after the treatment .

HY-166857

DMPE-PEG-amine TFA (MW 2000)	Drug Delivery
B12&" is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. "&B12&"can be used in drug delivery research ."

HY-W127737

Methylcobalamin hydrate

Mecobalamin hydrate

Biochemical Assay Reagents

Methylcobalamin Hydrate is a coenzyme required for methionine biosynthesis. Vitamins (hematopoiesis). It acts as a histamine receptor, Alzheimer study. Methylcobalamin is also used in the research of peripheral neuropathy, diabetic neuropathy, and as an initial research for amyotrophic lateral sclerosis. It can be used to prevent or research pathologies caused by vitamin B12 deficiency, such as pernicious anemia.

Cat. No.	Product Name

HY-K3004

RPMI 1640 (L-Glutamine, Phenol Red, no HEPES) 1 Publications Verification
RPMI 1640 contains glutathione and high concentration of vitamins, also contains biotin, vitamin B12, 4-Aminobenzoic acid (PABA) not found in MEM and DMEM, as well as high concentration of inositol and choline chloride.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-B0315

Vitamin B12 2 Publications Verification Cyanocobalamin	Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Vitamin B12 is a vitamin. Vitamin B12 plays a key role in the normal functioning of the brain and nervous system, and for the formation of blood. Vitamin B12 is beneficial for many inflammatory diseases and also provides protection in oxidative-stress-associated pathologies .

HY-112790

Adenosylcobalamin Coenzyme B12; Cobamamide; AdoCbl	Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Adenosylcobalamin (Coenzyme B12;Cobamamide;AdoCbl) is an active form of Vitamin B₁₂ which is a cofactor for methylmalonyl CoA mutase

HY-B2209

Hydroxocobalamin 2 Publications Verification Vitamin B12a	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Hydroxocobalamin (Vitamin B12a) is an injectable naturally occurring form of vitamin B12 with a favorable adverse effect profile, used as a dietary supplement in the treatment of vitamin B12 deficiency including pernicious anemia .

HY-B0586

Methylcobalamin 1 Publications Verification Mecobalamin; CH3-B12	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Methylcobalamin (CH3-B12), a cobalamin, is a form of vitamin B12.

HY-B2209B

Hydroxocobalamin acetate 2 Publications Verification Vitamin B12a acetate	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Hydroxocobalamin acetate is an injectable naturally occurring form of vitamin B12 with a favorable adverse effect profile, used as a dietary supplement in the research of vitamin B12 deficiency including pernicious anemia .

HY-B2209A

Hydroxocobalamin monohydrochloride 2 Publications Verification Vitamin B12a monohydrochloride	Structural Classification Natural Products Human Gut Microbiota Metabolites Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Hydroxocobalamin monohydrochloride (Vitamin B12a monohydrochloride) is an injectable naturally occurring form of vitamin B12 with a favorable adverse effect profile, used as a dietary supplement in the treatment of vitamin B12 deficiency including pernicious anemia .

HY-B0315R

*Vitamin B12* (Standard)**	Structural Classification Natural Products Microorganisms Source classification Endogenous metabolite	Endogenous Metabolite
Vitamin B12 (Standard) is the analytical standard of Vitamin B12. This product is intended for research and analytical applications. Vitamin B12 is a vitamin. Vitamin B12 plays a key role in the normal functioning of the brain and nervous system, and for the formation of blood .

HY-B0315A

Biotin-Vitamin B12	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Biotin-Vitamin B12 is the biotinylated Vitamin B12. Vitamin B12 is a vitamin that plays a key role in the normal functioning of the brain and nervous system, and for the formation of blood .

HY-B2209R

Hydroxocobalamin (Standard)	Structural Classification Natural Products Source classification Endogenous metabolite	Endogenous Metabolite
Hydroxocobalamin (Standard) is the analytical standard of Hydroxocobalamin. This product is intended for research and analytical applications. Hydroxocobalamin (Vitamin B12a) is an injectable naturally occurring form of vitamin B12 with a favorable adverse effect profile, used as a dietary supplement in the treatment of vitamin B12 deficiency including pernicious anemia .

HY-B2209BR

Hydroxocobalamin acetate (Standard) Vitamin B12a acetate (Standard)	Structural Classification Natural Products Source classification Endogenous metabolite	Endogenous Metabolite
Hydroxocobalamin (acetate) (Standard) is the analytical standard of Hydroxocobalamin (acetate). This product is intended for research and analytical applications. Hydroxocobalamin acetate is an injectable naturally occurring form of vitamin B12 with a favorable adverse effect profile, used as a dietary supplement in the research of vitamin B12 deficiency including pernicious anemia .

HY-113092

Propionylcarnitine	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease markers Endocrine diseases Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Propionylcarnitine is metabolized by carnitine acetyltransferase from propionyl-CoA. Increased propionylcarnitine is regarded as a biomarker of vitamin B12 deficiency .

HY-B0586R

Methylcobalamin (Standard)	Structural Classification Natural Products Source classification Endogenous metabolite	Endogenous Metabolite
Methylcobalamin (Standard) is the analytical standard of Methylcobalamin. This product is intended for research and analytical applications. Methylcobalamin (CH3-B12), a cobalamin, is a form of vitamin B12.

HY-103395

Methylmalonic acid 1 Publications Verification Methylpropanedioic acid; Methylmalonate	Structural Classification Human Gut Microbiota Metabolites Immune System Disorder Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Disease markers Endocrine diseases Endogenous metabolite Disease Research Fields Cancer	Endogenous Metabolite
Methylmalonic acid (Methylmalonate) is an indicator of Vitamin B-12 deficiency in cancer.

HY-112790R

Adenosylcobalamin (Standard)	Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms Source classification Endogenous metabolite	Endogenous Metabolite
Adenosylcobalamin (Standard) is the analytical standard of Adenosylcobalamin. This product is intended for research and analytical applications. Adenosylcobalamin (Coenzyme B12;Cobamamide;AdoCbl) is an active form of Vitamin B₁₂ which is a cofactor for methylmalonyl CoA mutase

HY-W040821

DL-Homocysteine 2 Publications Verification	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease markers Other Diseases Endocrine diseases Nervous System Disorder Endogenous metabolite Disease Research Fields Cardiovascular System Disorder	Endogenous Metabolite
DL-Homocysteine is a weak neurotoxin, and can affect the production of kynurenic acid in the brain. DL-Homocysteine is correlated with Vitamin B12, renal functions and folate levels, affects the cross-sectional cognition indirectly through white matter microstructural integrity .

HY-B2209AR

Hydroxocobalamin monohydrochloride (Standard)	Structural Classification Natural Products Human Gut Microbiota Metabolites Source classification Endogenous metabolite	Endogenous Metabolite
Hydroxocobalamin (monohydrochloride) (Standard) is the analytical standard of Hydroxocobalamin (monohydrochloride). This product is intended for research and analytical applications. Hydroxocobalamin monohydrochloride (Vitamin B12a monohydrochloride) is an injectable naturally occurring form of vitamin B12 with a favorable adverse effect profile, used as a dietary supplement in the treatment of vitamin B12 deficiency including pernicious anemia .

HY-103395R

Methylmalonic acid (Standard) Methylpropanedioic acid (Standard); Methylmalonate (Standard)	Structural Classification Human Gut Microbiota Metabolites Immune System Disorder Microorganisms Ketones, Aldehydes, Acids Disease markers Endocrine diseases Endogenous metabolite	Endogenous Metabolite
Methylmalonic acid (Standard) is the analytical standard of Methylmalonic acid. This product is intended for research and analytical applications. Methylmalonic acid (Methylmalonate) is an indicator of Vitamin B-12 deficiency in cancer.

HY-113045

Aquacobalamin	Microorganisms Source classification	Endogenous Metabolite
Aquacobalamin is one of the major forms of vitamin B12 isolated from mammalian cells. Aquacobalamin accelerates the oxidation of azo-dye Orange II (HY-N1442) by HSO₅ ^- in aqueous solutions. Aquacobalamin binds hydrogen peroxide reversibly to form a cobalt(III) hydroperoxo adduct with a 0.25 mM dissociation constant .

HY-N13061

Nervon	Structural Classification Animals Source classification Saccharides Monosaccharides	Others
Nervon is a crystalline cerebroside. Nervon can be used for the research of peripheral neuropathies and megaloblastic anemia caused by vitamin B12 deficiency .

HY-137808

Succinyl-Coenzyme A sodium Succinyl-CoA sodium	Structural Classification Natural Products Neurological Disease Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Succinyl-Coenzyme A (Succinyl-CoA) sodium is an intermediate of the citric acid cycle. Succinyl-Coenzyme A sodium can be converted to succinic acid and can also combines with glycine to form δ-ALA to synthesize porphyrins (heme). Succinyl-Coenzyme A sodium can be used in the study of metabolic, neurological and haematological abnormalities (such as porphyrias) caused by nutritional vitamin B₁₂ deficiency (resulting in a deficiency in Succinyl-Coenzyme A synthesis) .

HY-126791

Methylmalonyl-CoA Isosuccinyl coenzyme A; Methylmalonyl coenzyme A	Structural Classification Natural Products Human Gut Microbiota Metabolites Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Methylmalonyl coenzyme A (Methylmalonyl-CoA) is a catabolite of valine, isoleucine, methionine, threonine, odd-chain fatty acids, and cholesterol. Methylmalonyl coenzyme A tetralithium is converted to succinyl-CoA by enzymatic reaction of methylmalonyl-CoA mutase (MCM) with coenzyme vitamin B12 .

HY-126791A

Methylmalonyl-CoA tetralithium Isosuccinyl coenzyme A tetralithium; Methylmalonyl coenzyme tetralithium	Structural Classification Natural Products Human Gut Microbiota Metabolites Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Methylmalonyl-CoA (Methylmalonyl coenzyme A) tetralithium is a catabolite of valine, isoleucine, methionine, threonine, odd-chain fatty acids, and cholesterol. Methylmalonyl-CoA tetralithium is converted to succinyl-CoA by enzymatic reaction of methylmalonyl-CoA mutase (MCM) with coenzyme vitamin B12 .

Species:	Human (2) Mouse (1)
Tag:	His (3)
Source:	HEK293 (1) Sf9 insect cells (1) P. pastoris (1)

Cat. No.	Compare	Product Name	Species	Source

HY-P71304

	*Serpin B12* Protein, Human (HEK293, His)** SERPINB12; Serpin B12; Serine Protease Inhibitor-clade B12	Human	HEK293
	Serpin B12 Protein inhibits trypsin and plasmin, excluding thrombin, coagulation factor Xa, or urokinase-type plasminogen activator. It may have a role in cell differentiation, interacting with SLFN12 in a pathway regulating differentiation, and potentially interacting with USP14. Serpin B12 Protein, Human (HEK293, His) is the recombinant human-derived Serpin B12 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Serpin B12 Protein, Human (HEK293, His) is 425 a.a., with molecular weight of ~55.0 kDa.

HY-P77197

	*Serpin B12* Protein, Mouse (sf9, His)** SERPINB12; Serpin B12; Serine Protease Inhibitor-clade B12	Mouse	Sf9 insect cells
	Serpin B12 inhibits trypsin and plasmin but not thrombin, coagulation factor Xa, and urokinase-type plasminogen activator. Additionally, it interacts with SLFN12, contributing to cellular differentiation pathways, showcasing its multifunctional nature beyond classical protease inhibition. Serpin B12 Protein, Mouse (sf9, His) is the recombinant mouse-derived Serpin B12 protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of Serpin B12 Protein, Mouse (sf9, His) is 423 a.a., with molecular weight of ~58 kDa.

HY-P71789

	TCN1 Protein, Human (P.pastoris, His) Haptocorin; Haptocorrin; HC; Transcobalamin 1; Vitamin B12 binding protein; Vitamin B12 binding protein R binder family	Human	P. pastoris
	The TCN1 protein is critical for mitochondrial processes and binds to the mitochondrial light chain promoter to regulate mitochondrial transcription. As a key component of the mitochondrial transcription initiation complex (including TFB2M and POLRMT), TCN1 plays a crucial role in the basal transcription of mitochondrial DNA. TCN1 Protein, Human (P.pastoris, His) is the recombinant human-derived TCN1 protein, expressed by P. pastoris , with N-His labeled tag. The total length of TCN1 Protein, Human (P.pastoris, His) is 410 a.a., with molecular weight of ~47.6 kDa.

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HY-B0315S

*Vitamin B12-13C7*
Vitamin B12- ¹³C₇ is the ¹³C-labeled Vitamin B12. Vitamin B12 is a vitamin. Vitamin B12 plays a key role in the normal functioning of the brain and nervous system, and for the formation of blood[1][2].

HY-103395S

Methylmalonic acid-d3
Methylmalonic acid-d₃ is the deuterium labeled Methylmalonic acid. Methylmalonic acid (Methylmalonate) is an indicator of Vitamin B-12 deficiency in cancer[1][2].

HY-103395S1

Methylmalonic acid-13C4
Methylmalonic acid- ¹³C₄ is the ¹³C labeled Methylmalonic acid[1]. Methylmalonic acid (Methylmalonate) is an indicator of Vitamin B-12 deficiency in cancer[2].

HY-17016S

Oseltamivir-d5 phosphate
Oseltamivir-d₅ (phosphate) is the deuterium labeled Oseltamivir phosphate. Oseltamivir phosphate (GS 4104) is a neuraminidase inhibitor recommended for the treatment and prophylaxis of influenza A and B[1][2].

HY-B0822S1

Fipronil-13C6

Fipronil- ¹³C₆ is the ¹³C-labeled Fipronil. Fipronil is an insecticide that acts as a selective antagonist of insect GABA receptors (IC50s = 30 nM and 1,600 nM for cockroach and rat receptors, respectively). Fipronil also inhibits desensitizing and non-desensitizing glutamate-induced chloride currents in cockroach neurons (IC50s = 800 nM and 10 nM, respectively). Fipronil induces activity of the cytochrome P450 (CYP) isoforms CYP1A1/2, CYP2B1/2, and CYP3A1/2 in isolated rat liver microsomes.

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HY-P81760

	C4A Antibody (YA1505) Acidic C4; Acidic complement C4; Basic C4; Basic complement C4; C4A; C4A2; C4A3; C4A4; C4A6; C4AD; C4B1; C4B12; C4B2; C4B3; C4BD; C4F; C4S; CPAMD2; CPAMD3	WB, IHC-P, FC	Human
	C4A Antibody (YA1505) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1505), targeting C4A, with a predicted molecular weight of 193 kDa (observed band size: 193 kDa). C4A Antibody (YA1505) can be used for WB, IHC-P, FC experiment in human background.

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