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Results for "

CT1

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (1) Bacterial (1) Bcl-2 Family (1) Bombesin Receptor (1) Endogenous Metabolite (1) Ferroptosis (1) JNK (1) Radionuclide-Drug Conjugates (RDCs) (1)
By Research Areas:	Cancer (4) Infection (1)

Inhibitors & Agonists

Peptides

Recombinant Proteins

Antibodies

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-168894

*CT-1*	Ferroptosis	Cancer
CT-1 is a derivative of Cryptotanshinone (HY-N0174). CT-1 is a ferroptosis inducer. CT-1 promotes the interaction between NCOA4 and ferritin by targeting *FTH1, triggering ferritinophagy-mediated ferroptosis. CT-1* has anticancer activity against triple-negative breast cancer (TNBC). CT-1 induces ferroptosis in both N2-type tumor-associated neutrophils (TANs) and TNBC cancer cells ^[1].

HY-150596

CT1-3	Apoptosis Bcl-2 Family JNK	Cancer
CT1-3 is a potent anticancer agent. CT1-3 induces mitochondria-mediated apoptosis by regulating JNK/Bcl-2/Bax/XIAP pathway. CT1-3 suppresses the epithelial mesenchymal transition (EMT) potential of human cancer cells (HCCs) via regulating the E-cadherin/Snail axis, thus inhibits tumorigenesis. CT1-3 has a strong antitumor effect in mice model and exhibits no significant hepatic and renal toxicity ^[1].

HY-P10307

DOTA-ubiquicidin (29–41)	Radionuclide-Drug Conjugates (RDCs) Bacterial	Infection
DOTA-ubiquicidin (29-41), an antimicrobial peptide fragment derivative, can be used for synthesis of [ ⁶⁸Ga]Ga-DOTA-Ubiquicidin_29-41 and then used for imaging of infectious processes using PET/CT . DOTA-ubiquicidin (29–41) can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs).

HY-P10896

NOTA-P2-RM26	Bombesin Receptor	Cancer
NOTA-P2-RM26 is an antagonist of Bombesin (HY-P0195) analogs, and the gastrin-releasing peptide receptor (GRPR/BB2) is a molecular target for prostate cancer visualization. NOTA-P2-RM26 is labeled with ¹¹¹In and ⁶⁸Ga for prostate cancer imaging studies using PET and SPECT/CT .

HY-159803

IST-622 6-O-(3-Ethoxypropionyl)-3',4'-O-exo-benzylidenechartreusin	Endogenous Metabolite	Cancer
IST-622 (6-O-(3-Ethoxypropionyl)-3',4'-O-exo-benzylidenechartreusin) is an anti-tumor agent with significant growth inhibitory activity. IST-622 exhibits significant anti-tumor effects against a variety of mouse tumors such as P388 and L1210 leukemias, B16 melanoma, Lewis lung carcinoma, Colon 26 and Colon 38 adenocarcinomas, and M5076 reticulum cell sarcoma. IST-622 was orally administered and the results showed efficacy in different tumor types. In addition, IST-622 provided significant inhibitory effects against two human tumor xenograft models: large cell lung carcinoma (Lu-116) and gastric adenocarcinoma (St-4). IST-622 also exhibited significant growth inhibitory activity against P388 leukemia in vitro, with a half inhibitory concentration (IC50) more than 20 times lower than CT .

Cat. No.	Product Name	Target	Research Area

HY-P10307

DOTA-ubiquicidin (29–41)	Radionuclide-Drug Conjugates (RDCs) Bacterial	Infection
DOTA-ubiquicidin (29-41), an antimicrobial peptide fragment derivative, can be used for synthesis of [ ⁶⁸Ga]Ga-DOTA-Ubiquicidin_29-41 and then used for imaging of infectious processes using PET/CT . DOTA-ubiquicidin (29–41) can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs).

HY-P10896

NOTA-P2-RM26	Bombesin Receptor	Cancer
NOTA-P2-RM26 is an antagonist of Bombesin (HY-P0195) analogs, and the gastrin-releasing peptide receptor (GRPR/BB2) is a molecular target for prostate cancer visualization. NOTA-P2-RM26 is labeled with ¹¹¹In and ⁶⁸Ga for prostate cancer imaging studies using PET and SPECT/CT .

Species:	Human (13) Rat (1) Mouse (1)
Tag:	His (10) Tag Free (4) Avi (8) Fc (1)
Source:	HEK293 (12) CHO (1) E. coli (2)

Cat. No.	Compare	Product Name	Species	Source

HY-P71924

	Cardiotrophin-1/CTF1 Protein, Rat CTf1; Cardiotrophin-1; CT-1	Rat	E. coli
	Cardiotropin-1/CTF1 protein plays a key role in inducing cardiomyocyte hypertrophy in vitro. Its effects on myocardial development and enlargement are mediated through binding and activation of ILST/gp130 receptors. Cardiotrophin-1/CTF1 Protein, Rat is the recombinant rat-derived Cardiotrophin-1/CTF1 protein, expressed by E. coli , with tag free. The total length of Cardiotrophin-1/CTF1 Protein, Rat is 203 a.a., with molecular weight of ~21.4 kDa.

HY-P72871

	Cardiotrophin-1/CTF1 Protein, Human (HEK293, Fc) Cardiotrophin-1; CT-1; CTF1	Human	HEK293
	Cardiotrophin-1/CTF1 protein induces cardiac myocyte hypertrophy in vitro by binding to and activating the ILST/gp130 receptor, highlighting its regulatory role in heart muscle cell enlargement. This engagement orchestrates signaling events that contribute to the hypertrophic response, providing insight into the mechanisms of cardiac hypertrophy and implicating Cardiotrophin-1 in heart muscle growth. Cardiotrophin-1/CTF1 Protein, Human (HEK293, Fc) is the recombinant human-derived Cardiotrophin-1/CTF1 protein, expressed by HEK293 , with N-hFc labeled tag. The total length of Cardiotrophin-1/CTF1 Protein, Human (HEK293, Fc) is 200 a.a., with molecular weight of 54 & 37 kDa, respectively.

HY-P7149

	Cardiotrophin-1/CTF1 Protein, Human (CHO) rHuCT-1; CTF1	Human	CHO
	Cardiotrophin-1/CTF1 Protein, Human (CHO), a member of IL-6 family of cytokines, is a key regulator of energy homeostasis and of glucose and lipid metabolism.

HY-P7150

	Cardiotrophin-1/CTF1 Protein, Mouse (HEK293) rMuCT-1; CTF1	Mouse	HEK293
	Cardiotrophin-1/CTF1 Protein, Mouse (HEK293, His), a member of IL-6 family of cytokines, is required for cardiac myocyte maturation and plays an important role in the differentiation, development, and survival of neural stem cells.

HY-P7739

	Cardiotrophin-1/CTF1 Protein, Human (His) rHuCardiotrophin-1, His; Cardiotrophin-1; CT-1; CTF1	Human	E. coli
	Cardiotrophin-1/CTF1 Protein, Human (His) is an approximately 25.0 kDa human cardiotrophin-1 protein with a His-flag. Cardiotrophin-1belongs to the IL-6 family and can act as a cytoprotective molecule.

HY-P72870

	Cardiotrophin-1/CTF1 Protein, Human (HEK293) Cardiotrophin-1; CT-1; CTF1	Human	HEK293
	Cardiotrophin-1/CTF1 protein induces cardiac myocyte hypertrophy in vitro by binding to and activating the ILST/gp130 receptor, highlighting its regulatory role in heart muscle cell enlargement. This engagement orchestrates signaling events that contribute to the hypertrophic response, providing insight into the mechanisms of cardiac hypertrophy and implicating Cardiotrophin-1 in heart muscle growth. Cardiotrophin-1/CTF1 Protein, Human (HEK293) is the recombinant human-derived Cardiotrophin-1/CTF1 protein, expressed by HEK293 , with tag free. The total length of Cardiotrophin-1/CTF1 Protein, Human (HEK293) is 200 a.a., with molecular weight of ~26.6 kDa.

HY-P700938

	*HLA-A2402 MAGE-A3 Complex Protein, Human (IMPKAGLLI, HEK293, His-Avi)** MAGE family member A3; HIP8; HYPD; CT1.3; MAGE3; MAGEA6	Human	HEK293
	HLA-A2402 MAGE-A3 Complex Protein, Human (IMPKAGLLI, HEK293, His-Avi) is the recombinant human-derived HLA-A2402 MAGE-A3 Complex protein, expressed by HEK293 , with C-Avi, C-His labeled tag. , has molecular weight of 55-60 kDa.

HY-P700935

	*HLA-A0101 MAGE-A3 Complex Protein, Human (Biotinylated, EVDPIGHLY, HEK293, His-Avi)** MAGE family member A3; HIP8; HYPD; CT1.3; MAGE3; MAGEA6	Human	HEK293
	HLA-A0201 MAGE-A3 Complex Protein, a vital member of the major histocompatibility complex (MHC) class I family, facilitates immune recognition and response to hepatitis B virus (HBV). By presenting HBV-derived peptides to cytotoxic T cells, it contributes to antiviral defense mechanisms within the MHC class I pathway, emphasizing its pivotal role in adaptive immunity and immune system surveillance against infected or aberrant cells. HLA-A0101 MAGE-A3 Complex Protein, Human (Biotinylated, EVDPIGHLY, HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-A0101 and B2M/Beta-2-microglobulin Protein, expressed by HEK293* , with C-Avi, C-His labeled tag and EVDPIGHLY peptide. HLA-A*0101 MAGE-A3 Complex Protein, Human (Biotinylated, EVDPIGHLY, HEK293, His-Avi), has molecular weight of 53-63 kDa.

HY-P700936

	*HLA-A0101 MAGE-A3 Complex Tetramer Protein, Human (EVDPIGHLY, HEK293, His-Avi)** MAGE family member A3; HIP8; HYPD; CT1.3; MAGE3; MAGEA6	Human	HEK293
	HLA-A0201 MAGE-A3 Complex Protein, a vital member of the major histocompatibility complex (MHC) class I family, facilitates immune recognition and response to hepatitis B virus (HBV). By presenting HBV-derived peptides to cytotoxic T cells, it contributes to antiviral defense mechanisms within the MHC class I pathway, emphasizing its pivotal role in adaptive immunity and immune system surveillance against infected or aberrant cells. HLA-A0101 MAGE-A3 Complex Tetramer Protein, Human (EVDPIGHLY, HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-A0101 and B2M/Beta-2-microglobulin Protein, expressed by HEK293* , with C-Avi, C-His labeled tag and EVDPIGHLY peptide. HLA-A*0101 MAGE-A3 Complex Tetramer Protein, Human (EVDPIGHLY, HEK293, His-Avi), has molecular weight of 260-265 kDa.

HY-P700937

	*HLA-A2402 MAGE-A3 Complex Protein, Human (Biotinylated, IMPKAGLLI, HEK293, His-Avi)** MAGE family member A3; HIP8; HYPD; CT1.3; MAGE3; MAGEA6	Human	HEK293
	HLA-A2402 MAGE-A3 Complex Protein, Human (Biotinylated, IMPKAGLLI, HEK293, His-Avi) is the recombinant human-derived HLA-A2402 MAGE-A3 Complex protein, expressed by HEK293 , with C-Avi, C-His labeled tag. , has molecular weight of 55-60 kDa.

HY-P700939

	*HLA-A2402 MAGE-A3 Complex Tetramer Protein, Human (IMPKAGLLI, HEK293, His-Avi)** MAGE family member A3; HIP8; HYPD; CT1.3; MAGE3; MAGEA6	Human	HEK293
	HLA-A2402 MAGE-A3 Complex Tetramer Protein, Human (IMPKAGLLI, HEK293, His-Avi) is the recombinant human-derived HLA-A2402 MAGE-A3 Complex Tetramer protein, expressed by HEK293 , with C-Avi, C-His labeled tag. , has molecular weight of 260-265 kDa.

HY-P77750

	*HLA-A0201 MAGE-A4 Complex Protein, Human (HEK293, His-Avi)** HLA0201; MHC I; MAGE-A4; CT1.4; MAGE4A; MAGE4B; MAGE-X2; member 4	Human	HEK293
	HLA-A0201 MAGE-A4 Complex Protein, a member of the major histocompatibility complex (MHC) class I family, is highlighted. Additionally, the Chimeric HLA-A0201 WT-1 Complex Tetramer is recognized within the MHC class I family. HLA-A0201 MAGE-A4 Complex Protein, Human (HEK293, His-Avi) is a recombinant protein dimer complex containing human-derived HLA-A0201 MAGE-A4 Complex protein, expressed by HEK293 , with C-Avi, C-His labeled tag. HLA-A*0201 MAGE-A4 Complex Protein, Human (HEK293, His-Avi), has molecular weight of 52-60 kDa.

HY-P77751

	*HLA-A0201 MAGE-A4 Complex Protein, Human (Biotinylated, HEK293, His-Avi)** HLA0201; MHC I; MAGE-A4; CT1.4; MAGE4A; MAGE4B; MAGE-X2; member 4	Human	HEK293
	HLA-A0201 MAGE-A4 Complex Protein, a member of the major histocompatibility complex (MHC) class I family, is highlighted. Additionally, the Chimeric HLA-A0201 WT-1 Complex Tetramer is recognized within the MHC class I family. HLA-A0201 MAGE-A4 Complex Protein, Human (Biotinylated, HEK293, His-Avi) is a recombinant protein dimer complex containing human-derived HLA-A0201 MAGE-A4 Complex protein, expressed by HEK293 , with C-Avi, C-His labeled tag. HLA-A*0201 MAGE-A4 Complex Protein, Human (Biotinylated, HEK293, His-Avi), has molecular weight of 52-60 kDa.

HY-P77752

	*HLA-A0201 MAGE-A4 Complex Tetramer Protein, Human (HEK293, His-Avi)** HLA0201; MHC I; MAGE-A4; CT1.4; MAGE4A; MAGE4B; MAGE-X2; member 4	Human	HEK293
	HLA-A0201 MAGE-A4 Complex Protein, a member of the major histocompatibility complex (MHC) class I family, is highlighted. Additionally, the Chimeric HLA-A0201 WT-1 Complex Tetramer is recognized within the MHC class I family. HLA-A0201 MAGE-A4 Complex Tetramer Protein, Human (HEK293, His-Avi) is a recombinant protein dimer complex containing human-derived HLA-A0201 MAGE-A4 Complex Tetramer protein, expressed by HEK293 , with C-Avi, C-His labeled tag. HLA-A*0201 MAGE-A4 Complex Tetramer Protein, Human (HEK293, His-Avi), has molecular weight of 260-265 kDa.

HY-P700420

	MAGEA4 Protein, Human (HEK293, His) MAGEA4; melanoma antigen family A, 4; MAGE4; melanoma-associated antigen 4; cancer/testis antigen family 1; member 4; CT1.4; MAGE 41; MAGE X2; MAGE4A; MAGE4B; melanoma associated antigen 4; MGC21336	Human	HEK293
	MAGEA4 protein critically regulates cell proliferation by inhibiting G1 phase arrest and negatively modulates p53-mediated apoptosis. Its role in controlling key checkpoints emphasizes its impact on cellular homeostasis, suggesting significance in averting aberrant cell growth. MAGEA4 Protein, Human (HEK293, His) is the recombinant human-derived MAGEA4 protein, expressed by HEK293, with C-10*His labeled tag. The total length of MAGEA4 Protein, Human (HEK293, His) is 317 a.a., with molecular weight of 36.7 kDa.

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HY-P83159

	SPT5 Antibody (YA2904) hSPT5; SPT5; SPT5H; supt5h; Tat CT1	WB, IHC-P, ICC/IF	Human, Mouse, Rat
	SPT5 Antibody (YA2904) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2904), targeting SPT5, with a predicted molecular weight of 121 kDa (observed band size: 155 kDa). SPT5 Antibody (YA2904) can be used for WB, IHC-P, ICC/IF experiment in human, mouse, rat background.

HY-P81364

	MAGEA3 Antibody (YA1109) HIP8; HYPD; CT1.3; MAGE3; MAGEA6	IHC-P	Human
	MAGEA3 Antibody (YA1109) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1109), targeting MAGEA3. MAGEA3 Antibody (YA1109) can be used for IHC-P experiment in human background.

HY-P82306

	MAGE1 Antibody (YA2051) CT1.1; MAGE1; MAGE1A; MAGEA1	WB, ICC/IF, FC	Human, Mouse, Rat
	MAGE1 Antibody (YA2051) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2051), targeting MAGE1, with a predicted molecular weight of 34 kDa (observed band size: 46 kDa). MAGE1 Antibody (YA2051) can be used for WB, ICC/IF, FC experiment in human, mouse, rat background.

HY-P81360

	MAGEA1 Antibody (YA1105) MAGEA1; MAGE1, MAGE1A; Melanoma-associated antigen 1; Antigen MZ2-E; Cancer/testis antigen 1.1 (CT1.1); MAGE-1 antigen	IHC-P	Human
	MAGEA1 Antibody (YA1105) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1105), targeting MAGEA1. MAGEA1 Antibody (YA1105) can be used for IHC-P experiment in human background.

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