Search Result
Results for "
Diphenyl
" in MedChemExpress (MCE) Product Catalog:
6
Biochemical Assay Reagents
11
Isotope-Labeled Compounds
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-W008151
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Mitochondrial Metabolism
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Metabolic Disease
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Diphenyl Phosphate inhibits growth and energy metabolism in zebrafish and mice in a sex-specific manner. Diphenyl Phosphate can inhibit the activity of SDH (respiratory complex II), reduce the expression of CPT1 and disrupts the integrity of the mitochondrial membrane. Diphenyl Phosphate may be used in research on metabolic diseases .
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- HY-118159
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DPPP
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Reactive Oxygen Species
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Others
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Diphenyl-1-pyrenylphosphine (DPPP) is a fluoregenic peroxide reactive probe. Diphenyl-1-pyrenylphosphine exhibits a unique phototriggered aggregation-induced emission (AIE)/aggregation-induced quenching (ACQ) transition with a remarkable third-order nonlinear optical signal change .
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- HY-Y1177
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- HY-B1966S
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- HY-D0970
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Direct Blue 14; Trypan Blue
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Fluorescent Dye
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Others
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Diphenyl Blue (Trypan Blue) is a cell active dye, the most commonly used dye for the identification of dead cells, of en used to test cell membrane integrity and cell viability. Diphenyl Blue staining is one of the methods for tissue and cell culture. When cells are deactivated or have incomplete cell membranes, Diphenyl Blue can stain them Blue. Normal living cells with intact cell membranes reject Diphenyl blue and do not stain them blue. However, macrophages are capable of phagocytosis of Diphenyl Blue, so it can be used as a living stain for macrophages .
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- HY-Y0339S
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- HY-W011599
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- HY-Y0339S1
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Isotope-Labeled Compounds
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Others
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Diphenyl ether-d4 is the deuterium labeled Diphenyl ether (HY-Y0339). Oxydibenzene is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
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- HY-W016324S
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- HY-W008151S
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DPhP-d10
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Isotope-Labeled Compounds
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Metabolic Disease
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Diphenyl Phosphate-d10 (DPhP-d10) is the deuterium labled Diphenyl Phosphate (HY-W008151). Diphenyl Phosphate inhibits growth and energy metabolism of zebrafish in a sex-specific manner.
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- HY-142784S
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- HY-N13364
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Others
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3-Hydroxy-1,5-diphenyl-1-pentanone is a natural product .
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- HY-N9698
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Others
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Others
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1,5-Diphenyl-2-penten-1-one is a natural product extracted from Stellera chamaejasme. 1,5-Diphenyl-2-penten-1-one has strong contact activity and very good anti-feedant activity against Aphis gossypii and Schizaphis graminum .
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- HY-142537S
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- HY-W717661
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- HY-W162983
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Others
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Neurological Disease
Inflammation/Immunology
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3,4-Diphenyl-5H-furan-2-one is a natural compound isolated from the endophytic fungus Aspergillus flavipes AIL8 derived from the mangrove plant Acanthus ilicifolius. 3,4-Diphenyl-5H-furan-2-one is a derivative of 2,3-diphenyltetrahydrofuran (DPTF), which is a COX-2 inhibitor. 3,4-Diphenyl-5H-furan-2-one can be used as a lead compound for inflammation and pain .
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- HY-W250743
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Others
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Others
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Cresyl diphenyl phosphate is a compound that disrupts lipid homeostasis in zebrafish embryos, causing alterations in lipid content and lipidomic profiles, as well as affecting gene expression and energy homeostasis. |
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- HY-W719518
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- HY-N10405
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Keap1-Nrf2
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Metabolic Disease
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(R)-5-Hydroxy-1,7-diphenyl-3-heptanone is a diarylheptanoid that can be found in Alpinia officinarum. (R)-5-Hydroxy-1,7-diphenyl-3-heptanone ameliorates oxidative stress and insulin resistance via activation of Nrf2/ARE pathway .
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- HY-N8826
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- HY-N13493
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Others
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Others
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5-Hydroxy-1,7-diphenyl-4-hepten-3-one is a natural product that can be isolated from Alpinia officinarum .
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- HY-D0059
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DIB-Cl
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Fluorescent Dye
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Others
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4-(4,5-Diphenyl-1H-imidazol-2-yl)benzoyl chloride (DIB-Cl) is a fluorescent labeling reagent. 4-(4,5-Diphenyl-1H-imidazol-2-yl)benzoyl chloride can be used for labeling amines and successfully being applied to determine activator amines by HPLC .
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- HY-W008432
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- HY-W276446
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Others
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Inflammation/Immunology
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1,1-Diphenyl-4-(pyrrolidin-1-yl)but-2-yn-1-ol is an anticholinergic agent. 1,1-Diphenyl-4-(pyrrolidin-1-yl)but-2-yn-1-ol has the potential for the research of bronchial asthma . 1,1-Diphenyl-4-(pyrrolidin-1-yl)but-2-yn-1-ol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-121914S
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- HY-W074143
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Fluorescent Dye
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Others
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Tris(4,7-diphenyl-1,10-phenanthroline)ruthenium(II) dichloride is an oxygen-sensitive fluorescent indicator widely used as a probe for luminescence detection and quantitative oxygen determination .
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- HY-D1474
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Biochemical Assay Reagents
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Others
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3,3'-Bis(3-sulfopropyl)-5,5'-diphenyl-9-ethyloxacarbocyanine betaine sodium is a photographic sensitizer in the green spectral region .
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- HY-112053
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DPPH
Maximum Cited Publications
15 Publications Verification
2,2-Diphenyl-1-picrylhydrazyl
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Others
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Metabolic Disease
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DPPH (2,2-Diphenyl-1-picrylhydrazyl) is a stable free radical that can be used to measure the radical scavenging activity of antioxidants. The odd electron of nitrogen atom in DPPH is reduced by receiving a hydrogen atom from antioxidants to the corresponding hydrazine. DPPH method may be utilized in aqueous and nonpolar organic solvents and can be used to examine both hydrophilic and lipophilic antioxidants .
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- HY-N2185R
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Others
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Inflammation/Immunology
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(5R,6E)-5-Hydroxy-1,7-diphenyl-6-hepten-3-one (Standard) is the analytical standard of (5R,6E)-5-Hydroxy-1,7-diphenyl-6-hepten-3-one. This product is intended for research and analytical applications. (5R,6E)-5-Hydroxy-1,7-diphenyl-6-hepten-3-one is the methylene chloride extract of Alpinia nutans, has antioxidant activity .
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- HY-W112057
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- HY-N2185
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(5R)-trans-1,7-Diphenyl-5-hydroxy-6-hepten-3-one
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Others
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Inflammation/Immunology
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(5R,6E)-5-Hydroxy-1,7-diphenyl-6-hepten-3-one is the methylene chloride extract of Alpinia nutans, has antioxidant activity .
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- HY-116710
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FAAH
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Others
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3-Decyl-5,5'-diphenyl-2-thioxo-4-imidazolidinone (compound 45) is a potential inhibitor of fatty acid amide hydrolase (FAAH) (pI50: 5.89) and is active against CB(1) and CB(2) ) Lack of affinity for cannabinoid receptors .
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- HY-N8997
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Others
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Others
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5-Hydroxy-1,7-diphenyl-4E,6E-dien-3-heptanone is a diarylheptanoid that can be found in dried rhizomes of Alpinia officinarum (Liangjiang) .
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- HY-B0230S
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COX
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Inflammation/Immunology
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Phenylbutazone(diphenyl-d10) is the deuterium labeled Phenylbutazone. Phenylbutazone is an efficient reducing cofactor for the peroxidase activity of prostaglandin H synthase (PHS). Phenylbutazone, a hepatotoxin, is a nonsteroidal anti-inflammatory agent (NSAID). Phenylbutazone induces muscle blind-like protein 1 (MBNL1) expression and has the potential for ankylosing spondylitis research[1][2].
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- HY-W008709
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Biochemical Assay Reagents
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Others
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4-(4,5-Diphenyl-1H-imidazol-2-yl)phenol is an organic compound commonly used in fluorescent dyes and catalysts. It can be used to prepare some organic light-emitting diodes (OLEDs) and organic solar cells, and is widely used in chemical sensors and analytical instruments. In addition, this compound is used as a catalyst or buffer in certain chemical reactions.
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- HY-W075433
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5,15-Di(4-Pyridyl)-10,20-Diphenylporphyrin
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Biochemical Assay Reagents
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Others
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5,15-Diphenyl-10,20-di(pyridin-4-yl)porphyrin is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-163977
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2,2-Diphenyl-1,3-dioxa-2-silacyclooct-5-ene
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Biochemical Assay Reagents
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Others
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Silyl-ether based ROMP Monomer (2,2-Diphenyl-1,3-dioxa-2-silacyclooct-5-ene) is a biochemical reagent that can be used in the synthesis of advanced polymer materials for biomedical applications, including drug delivery vehicles and hydrogels .
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- HY-119176
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Others
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Others
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Oxyfluorfen is a pre- and post-emergence diphenyl ether herbicide to control annual broad-leaved and grass weeds. Oxyfluorfen is a protoporphyrinogen oxidase inhibitor and inhibits photosynthesis by blocking chlorophyll synthesis .
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- HY-119176R
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Others
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Others
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Oxyfluorfen (Standard) is the analytical standard of Oxyfluorfen. This product is intended for research and analytical applications. Oxyfluorfen is a pre- and post-emergence diphenyl ether herbicide to control annual broad-leaved and grass weeds. Oxyfluorfen is a protoporphyrinogen oxidase inhibitor and inhibits photosynthesis by blocking chlorophyll synthesis .
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- HY-121900
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PPAR
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Metabolic Disease
Endocrinology
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LT175, a dual PPARα/γ ligand, is an orally active partial agonist against PPARγ(hPPARα:EC50=0.22 μm; mPPARα:EC50=0.26 μm; hPPARγ:EC50=0.48 μm). LT175 interacts with PPARγ and affects the recruitment of the coregulators cyclic-AMP response element-binding protein-binding protein and nuclear corepressor 1 (NCoR1). LT175 interacts with PPARγ in a hydrophobic region called “diphenyl pocket”. LT175 has potent insulin-sensitizing effects and reduced adipogenic properties .
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- HY-N12472
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Aldose Reductase
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Others
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Floramanoside C shows 2,2-diphenyl-1-picrylhydrazyl scavenging and aldose reductase inhibitory activities .
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- HY-W013343
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Biochemical Assay Reagents
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Others
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Diphenyl-2-pyridylphosphine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-N7518
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Others
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Inflammation/Immunology
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Eulophiol shows the 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging activity with an EC50 of 27.7μM. Antioxidant activity .
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- HY-N1859
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- HY-W274194
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Others
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Others
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Antioxidant agent-7 (SD-7) is a benzodiazepine derivative with antioxidant activity with an IC50 value of 470 nM to scavenge DPPH (2,2-diphenyl-1-picrylhydrazyl) free radical .
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- HY-N12871
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Aldose Reductase
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Others
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Floramanoside D is a flavonol glycoside. Floramanoside D inhibits aldose reductase (IC50 is 2.2 μM), scavenges the 2,2-diphenyl-1-picrylhydrazyl (DPPH) (SC50 is 12.5 μM) .
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- HY-W714006
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Others
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Metabolic Disease
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Cochliodinol (compound 1) is a metabolite derived from the Apis mellifera ligustica. Cochliodinol has strong free radical scavenging activity of 2, 2-diphenyl-1-picrohydrazine (DPPH) (IC50=3.06 μg/mL) .
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- HY-N9542
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Others
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Others
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Dimethylurea/citric acid is a highly efficient deep eutectic solvent (DES). Dimethylurea/citric acid can be used as a catalyst and a green reaction medium for the synthesis of bis(indolyl)methanes, quinolines and aryl-4, 5-diphenyl-1H-imidazoles.
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- HY-N10742
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Reactive Oxygen Species
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Cardiovascular Disease
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Maritimein is an aurone that can be isolated from Coreopsis tinctoria. Maritimein shows strong diphenyl(2,4,6-trinitrophenyl)iminoazanium (DPPH) radical-scavenging activity with an IC50 value of 4.12 μM. Maritimein can be used for the research of cardiovascular disease .
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- HY-N2443
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Bacterial
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Infection
Neurological Disease
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Tribuloside is a flavonoid that can be isolated from Tribulus terrestris L . Tribuloside exhibits anti-mycobacterial activity against the non-pathogenic Mycobacterium species with a minimum inhibitory concentration (MIC) of 5.0 mg/mL. Tribuloside has 1,1-diphenyl-2-picrylhydrazyl radical scavenging activity .
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- HY-N9814
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NO Synthase
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Inflammation/Immunology
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Shanciol B, isolated from the ethyl acetate extract of the air-dried whole plant of Pholidota imbricate Hook, inhibits nitric oxide (NO) production and 1,1-diphenyl-2-picrylhydrazil (DPPH) radical scavenging activity . Shanciol B is a microsomal prostaglandin E synthase-1 (mPGES-1) inhibitor with anti-inflammatory activity .
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- HY-163650
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Others
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Others
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DTPD-Q is the transformation products (TATPs) of tire additives N,N′-diphenyl-p-phenylenediamine (DTPD). DTPD-Q accumulates and rises the ecological risk in the environment .
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- HY-112053R
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Others
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Metabolic Disease
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DPPH (Standard) is the analytical standard of DPPH. This product is intended for research and analytical applications. DPPH (2,2-Diphenyl-1-picrylhydrazyl) is a stable free radical that can be used to measure the radical scavenging activity of antioxidants. The odd electron of nitrogen atom in DPPH is reduced by receiving a hydrogen atom from antioxidants to the corresponding hydrazine. DPPH method may be utilized in aqueous and nonpolar organic solvents and can be used to examine both hydrophilic and lipophilic antioxidants .
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- HY-122761
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mAChR
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Neurological Disease
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Quifenadine (Compound 3a), the hydroxyl-(diphenyl)methyl quinuclidine derivative, is a M3 receptor antagonist with an IC50 value > 1000 nM. Quifenadine can be used for the research of neurological disease .
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- HY-101605
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Dipeptidyl Peptidase
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Cardiovascular Disease
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Prodipine, a diphenyl-phosphonate derivative. The IC50s of Prodipine for purified and plasma Dipeptidyl peptidase IV (DPP IV) from the rabbit are 4.5 μM and 30 μM, respectively.
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- HY-N11997
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Cholinesterase (ChE)
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Neurological Disease
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Feralolide is a dihydroisocoumarin isolated from the methanolic extract of aloe vera resin. Feralolide is also a dual inhibitor of AChE and BuChE, with IC50s of 55 μg/mL and 52 μg/mL respectively. Feralolide has antioxidant activity and inhibits 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2, 2′-azinobis-3-ethylbenzothiazoline-6-sulfonic acid (ABTS). Feralolide could be used in research into cognitive disorders such as Alzheimer's disease, potentially restoring and enhancing memory .
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- HY-162691
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Others
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Others
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DEP-5 is an inhibitor of acetohydroxyacid synthase (AHAS) with an inhibition constant of 39.4 μM. DEP-5 is a diphenyl ether-pyrimidine hybrid with herbicidal activity against the Leptochloa chinensis(L.) Nees .
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- HY-160680
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Androgen Receptor
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Endocrinology
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AR antagonist 6 (compound 6i) is a diphenyl ether androgen receptor (AR) antagonist that binds AR at a concentration of 120 nM. AR antagonist 6 exhibits low toxicity and in vitro activity against the golden Syrian hamster ear model .
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- HY-P3350
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Bacterial
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Infection
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LS-BF1 is a stable and low toxic cationic antimicrobial peptide. LS-BF1 displays broad spectrum of antibacterial activity, including the challenging ESKAPE pathogens, by cell membrane disruptive mechanism. LS-BF1 shows good in vivo efficacy for elimination of bacteria in a mouse infection model[1].
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- HY-W725473
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Isotope-Labeled Compounds
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Others
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Oxyfluorfen-d5 is deuterated labeled Oxyfluorfen (HY-119176) Oxyfluorfen is a pre- and post-emergence diphenyl ether herbicide to control annual broad-leaved and grass weeds. Oxyfluorfen is a protoporphyrinogen oxidase inhibitor and inhibits photosynthesis by blocking chlorophyll synthesis.
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- HY-121914
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o-Chlorotriphenylmethanol
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Calcium Channel
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Neurological Disease
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(2-Chlorophenyl)diphenylmethanol (UCL 1880) is an analog of the metabolite 2-chlorophen-diphenyl-methanol (CBM) of 2-chlorophenyl, The IC50 for sI(AHP) inhibition is 1-2 μM. (2-chlorophenyl)diphenylmethanol is a weak Ca 2+ channel blocker .
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- HY-121914R
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Calcium Channel
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Neurological Disease
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(2-Chlorophenyl)diphenylmethanol (Standard) is the analytical standard of (2-Chlorophenyl)diphenylmethanol. This product is intended for research and analytical applications. (2-Chlorophenyl)diphenylmethanol (UCL 1880) is an analog of the metabolite 2-chlorophen-diphenyl-methanol (CBM) of 2-chlorophenyl, The IC50 for sI(AHP) inhibition is 1-2 μM. (2-chlorophenyl)diphenylmethanol is a weak Ca2+ channel blocker .
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- HY-105168
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Endothelin Receptor
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Cardiovascular Disease
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TAK 044 is an antagonist of Endothelin Receptor. TAK 044 strongly inhibits ET-induced deterioration in various animal models. TAK 044 can be used in study ET-related diseases such as acute myocardial infarction,acute renal failure, acute hepatic malfunction, and subarachnoid hemorrhage .
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- HY-P10563
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BHV-1100
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CD38
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Cancer
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Noraramtide (BHV-1100) is an antibody recruitment molecule. Noraramtide can specifically bind to CD38 molecules to recruit natural killer (NK) cells. Noraramtide enhances the ability of NK cells to kill tumor cells through antibody-dependent cellular cytotoxicity (ADCC). This mechanism allows NK cells to more effectively recognize and eliminate tumor cells while avoiding mutual killing between NK cells. Noraramtide can be used for the study of autologous cancer immunity .
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Cat. No. |
Product Name |
Type |
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- HY-118159
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DPPP
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Fluorescent Dyes/Probes
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Diphenyl-1-pyrenylphosphine (DPPP) is a fluoregenic peroxide reactive probe. Diphenyl-1-pyrenylphosphine exhibits a unique phototriggered aggregation-induced emission (AIE)/aggregation-induced quenching (ACQ) transition with a remarkable third-order nonlinear optical signal change .
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- HY-D0970
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Direct Blue 14; Trypan Blue
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Dyes
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Diphenyl Blue (Trypan Blue) is a cell active dye, the most commonly used dye for the identification of dead cells, of en used to test cell membrane integrity and cell viability. Diphenyl Blue staining is one of the methods for tissue and cell culture. When cells are deactivated or have incomplete cell membranes, Diphenyl Blue can stain them Blue. Normal living cells with intact cell membranes reject Diphenyl blue and do not stain them blue. However, macrophages are capable of phagocytosis of Diphenyl Blue, so it can be used as a living stain for macrophages .
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- HY-D0059
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DIB-Cl
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Fluorescent Dyes/Probes
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4-(4,5-Diphenyl-1H-imidazol-2-yl)benzoyl chloride (DIB-Cl) is a fluorescent labeling reagent. 4-(4,5-Diphenyl-1H-imidazol-2-yl)benzoyl chloride can be used for labeling amines and successfully being applied to determine activator amines by HPLC .
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- HY-W074143
-
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Fluorescent Dyes/Probes
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Tris(4,7-diphenyl-1,10-phenanthroline)ruthenium(II) dichloride is an oxygen-sensitive fluorescent indicator widely used as a probe for luminescence detection and quantitative oxygen determination .
|
Cat. No. |
Product Name |
Type |
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- HY-W011599
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- HY-W719518
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- HY-W008709
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Biochemical Assay Reagents
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4-(4,5-Diphenyl-1H-imidazol-2-yl)phenol is an organic compound commonly used in fluorescent dyes and catalysts. It can be used to prepare some organic light-emitting diodes (OLEDs) and organic solar cells, and is widely used in chemical sensors and analytical instruments. In addition, this compound is used as a catalyst or buffer in certain chemical reactions.
|
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- HY-W075433
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5,15-Di(4-Pyridyl)-10,20-Diphenylporphyrin
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Biochemical Assay Reagents
|
5,15-Diphenyl-10,20-di(pyridin-4-yl)porphyrin is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-163977
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2,2-Diphenyl-1,3-dioxa-2-silacyclooct-5-ene
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Biochemical Assay Reagents
|
Silyl-ether based ROMP Monomer (2,2-Diphenyl-1,3-dioxa-2-silacyclooct-5-ene) is a biochemical reagent that can be used in the synthesis of advanced polymer materials for biomedical applications, including drug delivery vehicles and hydrogels .
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- HY-W013343
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Biochemical Assay Reagents
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Diphenyl-2-pyridylphosphine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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Cat. No. |
Product Name |
Target |
Research Area |
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- HY-W008432
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- HY-W112057
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- HY-P3350
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Bacterial
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Infection
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LS-BF1 is a stable and low toxic cationic antimicrobial peptide. LS-BF1 displays broad spectrum of antibacterial activity, including the challenging ESKAPE pathogens, by cell membrane disruptive mechanism. LS-BF1 shows good in vivo efficacy for elimination of bacteria in a mouse infection model[1].
|
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- HY-105168
-
|
Endothelin Receptor
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Cardiovascular Disease
|
TAK 044 is an antagonist of Endothelin Receptor. TAK 044 strongly inhibits ET-induced deterioration in various animal models. TAK 044 can be used in study ET-related diseases such as acute myocardial infarction,acute renal failure, acute hepatic malfunction, and subarachnoid hemorrhage .
|
-
- HY-P10563
-
BHV-1100
|
CD38
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Cancer
|
Noraramtide (BHV-1100) is an antibody recruitment molecule. Noraramtide can specifically bind to CD38 molecules to recruit natural killer (NK) cells. Noraramtide enhances the ability of NK cells to kill tumor cells through antibody-dependent cellular cytotoxicity (ADCC). This mechanism allows NK cells to more effectively recognize and eliminate tumor cells while avoiding mutual killing between NK cells. Noraramtide can be used for the study of autologous cancer immunity .
|
Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
Cat. No. |
Product Name |
Chemical Structure |
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- HY-B1966S
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Diphenyl phthalate-3,4,5,6-d4 is the deuterium labeled Diphenyl phthalate[1].
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- HY-B0230S
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Phenylbutazone(diphenyl-d10) is the deuterium labeled Phenylbutazone. Phenylbutazone is an efficient reducing cofactor for the peroxidase activity of prostaglandin H synthase (PHS). Phenylbutazone, a hepatotoxin, is a nonsteroidal anti-inflammatory agent (NSAID). Phenylbutazone induces muscle blind-like protein 1 (MBNL1) expression and has the potential for ankylosing spondylitis research[1][2].
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- HY-Y0339S
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Diphenyl Ether-d10 is the deuterium labeled Diphenyl Ether[1].
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- HY-Y0339S1
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Diphenyl ether-d4 is the deuterium labeled Diphenyl ether (HY-Y0339). Oxydibenzene is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
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- HY-W016324S
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Diphenyl-2,2′,4,4′,6,6′-methylamine-d6 is the deuterium labeled Diphenyl-methylamine[1].
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- HY-W008151S
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Diphenyl Phosphate-d10 (DPhP-d10) is the deuterium labled Diphenyl Phosphate (HY-W008151). Diphenyl Phosphate inhibits growth and energy metabolism of zebrafish in a sex-specific manner.
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- HY-142784S
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Isopropyl diphenyl phosphate-d7 is the deuterium labeled Isopropyl diphenyl phosphate[1].
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- HY-142537S
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p-t-Butylphenyl diphenyl phosphate-d10 is the deuterium labeled p-t-Butylphenyl diphenyl phosphate[1].
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- HY-W717661
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4-Hydroxyphenyl diphenyl phosphate-d10 is the deuterium labeled 4-Hydroxyphenyl diphenyl phosphate-d10 (HY-W717661) .
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- HY-121914S
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(2-Chlorophenyl)diphenyl-methanol-d5 is the deuterium labeled (2-Chlorophenyl)diphenylmethanol[1].
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- HY-W725473
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Oxyfluorfen-d5 is deuterated labeled Oxyfluorfen (HY-119176) Oxyfluorfen is a pre- and post-emergence diphenyl ether herbicide to control annual broad-leaved and grass weeds. Oxyfluorfen is a protoporphyrinogen oxidase inhibitor and inhibits photosynthesis by blocking chlorophyll synthesis.
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