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Results for "

HMGB 1

" in MedChemExpress (MCE) Product Catalog:

By Targets:	AMPK (1) Amyloid-β (2) Apoptosis (5) Autophagy (2) Bacterial (1) CXCR (1) Ferroptosis (3) HDAC (1) Interleukin Related (2) Isotope-Labeled Compounds (1) NF-κB (3) NOD-like Receptor (NLR) (1) Pyroptosis (2) Reactive Oxygen Species (1) RIP kinase (2) ROCK (1) Small Interfering RNA (siRNA) (1) TNF Receptor (3) Toll-like Receptor (TLR) (2) Virus Protease (5) β-catenin (1)
By Research Areas:	Cancer (13) Cardiovascular Disease (3) Inflammation/Immunology (22) Metabolic Disease (5) Neurological Disease (5)
Oligonucleotides:	Pre-designed siRNA Sets (1) siRNAs (1)

Inhibitors & Agonists

Peptides

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-155751

HMGB1-IN-1	Interleukin Related TNF Receptor NOD-like Receptor (NLR)	Inflammation/Immunology
HMGB1-IN-1 (compound 6) displays strong NO inhibitory effect in RAW264.7 cells with IC₅₀ value of 15.9 ± 0.6 μM. HMGB1-IN-1 inhibit the HMGB1/NF-κB/NLRP3 pathway. HMGB1-IN-1 shows good anti-inflammatory activity and good anti-sepsis effects in kidney injury .

HY-124750

NecroX-7	TNF Receptor Interleukin Related Toll-like Receptor (TLR) Reactive Oxygen Species	Cardiovascular Disease Inflammation/Immunology
NecroX-7 is a potent free radical scavenger and a *HMGB1* (high-mobility group box 1) inhibitor. NecroX-7 can be used as an antidote to acetaminophen toxicity. NecroX-7 exerts a protective effect by preventing the release of HMGB1 in ischemia/reperfusion injury. NecroX-7 inhibits the HMGB1-induced release of TNF and IL-6, as well as the expression of TLR-4 and receptor for advanced glycation end products. NecroX-7 can be used graft-versus-host disease (GVHD) research .

HY-N0184

Glycyrrhizic acid 25+ Cited Publications Glycyrrhizin	Virus Protease	Metabolic Disease Cancer
Glycyrrhizic acid is a triterpenoid saponinl, acting as a direct *HMGB1* antagonist, with anti-tumor, anti-diabetic activities.

HY-113772

Inflachromene	Others	Neurological Disease Inflammation/Immunology
Inflachromene, a microglial inhibitor, binds to *HMGB1* and *HMGB2* and exerts anti-inflammatory effects. Inflachromene effectively downregulates proinflammatory functions of *HMGB* and reduces neuronal damage. Inflachromene can be used for the research of neuroinflammatory disorders .

HY-N0184A

Dipotassium glycyrrhizinate 25+ Cited Publications Glycyrrhizic acid dipotassium; Dipotassium glycyrrhizate	Virus Protease	Metabolic Disease Inflammation/Immunology
Dipotassium glycyrrhizinate is a *HMGB1* inhibitor, inhibits atopic dermatitis-related gene expression with anti-anti-inflammatory activity .

HY-P2268

RAGE antagonist peptide 2 Publications Verification	Amyloid-β	Inflammation/Immunology Cancer
RAGE antagonist peptide is an advanced glycation end products (RAGE) antagonist. RAGE antagonist peptide prevents RAGE from binding with several of its most important ligands, including HMGB-1, S100P, and S100A4. RAGE antagonist peptide (RAP) possesses anti-tumor and anti-inflammatory activities .

HY-RS06232

HMGB1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
HMGB1 Human Pre-designed siRNA Set A contains three designed siRNAs for HMGB1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HMGB1 Human Pre-designed siRNA Set A HMGB1 Human Pre-designed siRNA Set A

HY-155759

HMGB1-IN-2	Others	Inflammation/Immunology Cancer
HMGB1-IN-2 (compound 15) is an inhibitor of highly conserved nuclear protein (HMGB1), showing NO inhibitory effect with IC₅₀ value of 20.2 μM in RAW264.7 cells. HMGB1-IN-2 (30 μM) decreases the level of IL-1 β, TNF-α, caspase-1 p20, inhibits the phosphorylation of NF-κB p65, exhibits anti-apoptotic activity. HMGB1-IN-2 (15 mg/kg; ip) relives kidney injury in septic acute kidney injury mouse. HMGB1-IN-2 inhibits Huh7 cells and A549 cells with IC₅₀s of 77.0 μM, and 82.0 μM, respectively .

HY-168053

HMGB1-IN-3	Others	Inflammation/Immunology
HMGB1-IN-3 (compound E) is a glycyrrhizic acid derivative with strong inhibitory activity against *HMGB1* (high mobility group protein 1) and can be used in the study of intracerebral hemorrhage .

HY-P10321

HBP08	CXCR	Inflammation/Immunology
HBP08 is a selective inhibitor of *CXCL12/HMGB1* interaction. HBP08 has a high affinity for HMGB1 (K_d=0.8 μM). HBP08 inhibits CXCL12-mediated cell migration .

HY-P2268A

RAGE antagonist peptide TFA 2 Publications Verification	Amyloid-β	Inflammation/Immunology Cancer
RAGE antagonist peptide TFA is an advanced glycation end products (RAGE) antagonist. RAGE antagonist peptide TFA prevents RAGE from binding with several of its most important ligands, including HMGB-1, S100P, and S100A4. RAGE antagonist peptide TFA possesses anti-tumor and anti-inflammatory activities .

HY-143456

Anti-inflammatory agent 18	Others	Inflammation/Immunology
Anti-inflammatory agent 18 (compound 3b) shows NO inhibitory activity, with an IC₅₀ of 15.94 μM. Anti-inflammatory agent 18 inhibits HMGB1-induced later inflammation. Anti-inflammatory agent 18 can be used for the research of later inflammation diseases such as coronavirus diseases (COVID-19) and sepsis, etc .

HY-143457

Anti-inflammatory agent 19	Others	Inflammation/Immunology
Anti-inflammatory agent 19 (compound 2b) shows NO inhibitory activity, with an IC₅₀ of 36.00 μM. Anti-inflammatory agent 19 inhibits HMGB1-induced later inflammation. Anti-inflammatory agent 19 can be used for the research of later inflammation diseases such as coronavirus diseases (COVID-19) and sepsis, etc .

HY-N0184R

Glycyrrhizic acid (Standard)	Virus Protease	Metabolic Disease Cancer
Glycyrrhizic acid (Standard) is the analytical standard of Glycyrrhizic acid. This product is intended for research and analytical applications. Glycyrrhizic acid is a triterpenoid saponinl, acting as a direct *HMGB1* antagonist, with anti-tumor, anti-diabetic activities.

HY-162065

N6F11	Ferroptosis	Cancer
N6F11 is a selective ferroptosis inducer, and can selectively induce ferroptosis by targeting TRIM25-mediated GPX4 degradation in cancer cells while sparing immune cells. N6F11 initiates HMGB1-dependent antitumor immunity mediated by CD8 ⁺ T cells .

HY-N0184S

Glycyrrhizic acid-d3 Glycyrrhizin-d₃	Isotope-Labeled Compounds Virus Protease	Metabolic Disease Cancer
Glycyrrhizic acid-d₃ (Glycyrrhizin-d₃) is deuterium labeled Glycyrrhizic acid. Glycyrrhizic acid is a triterpenoid saponinl, acting as a direct *HMGB1* antagonist, with anti-tumor, anti-diabetic activities .

HY-N0184AR

Dipotassium glycyrrhizinate (Standard)	Virus Protease	Metabolic Disease Inflammation/Immunology
Dipotassium glycyrrhizinate (Standard) is the analytical standard of Dipotassium glycyrrhizinate. This product is intended for research and analytical applications. Dipotassium glycyrrhizinate is a HMGB1 inhibitor, inhibits atopic dermatitis-related gene expression with anti-anti-inflammatory activity .

HY-163409

CGK012	β-catenin	Inflammation/Immunology Cancer
CKG012 is an inhibitor for Wnt/βcatenin signaling pathway. CGK012 inhibits release of HMGB1 and transcription of β-catenin, exhibits attenuating activities against cecal ligation and puncture (CLP)-induced sepsis and multiple myeloma cancer .

HY-B0581

Dexrazoxane 5+ Cited Publications ICRF-187; ADR-529; NSC-169780	Ferroptosis Apoptosis	Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
Dexrazoxane, as an intracellular iron chelating agent, reduces the formation of superoxide radicals and has cardioprotective, anti-inflammatory, antioxidant, anti-tumor and neuroprotective activities. Dexrazoxane inhibits ferroptosis of H9c2 cells by inhibiting HMGB1. Dexrazoxane induces DNA damage and apoptosis in human fibrosarcoma cells .

HY-Y1362

Ethyl pyruvate 5 Publications Verification	Autophagy Apoptosis Pyroptosis NF-κB	Inflammation/Immunology Cancer
Ethyl pyruvate is a simple derivative of the endogenous metabolite pyruvate. Ethyl pyruvate is an *HMGB1* release inhibitor. Ethyl pyruvate can induce apoptosis by autophagy. Ethyl pyruvate has anti-inflammatory, antioxidant and anti-tumor activity. Ethyl pyruvate can be used in the study of neurodegenerative diseases such as Alzheimer's and Parkinson's disease .

HY-N9587

Tricin 7-O-β-D-glucopyranoside	Apoptosis	Neurological Disease
Tricin 7-O-β-D-glucopyranoside is a potent and orally active neuroprotective agent. Tricin 7-O-β-D-glucopyranoside induces Apoptosis. Tricin 7-O-β-D-glucopyranoside decreases the expression of TNF-α induced phosphor-κB-α, phosphor-NF-κB, HMGB1 .

HY-101872

GSK-872 Maximum Cited Publications 64 Publications Verification	RIP kinase	Inflammation/Immunology
GSK-872 is a RIPK3 inhibitor, which binds RIP3 kinase domain with an IC₅₀ of 1.8 nM, and inhibits kinase activity with an IC₅₀ of 1.3 nM. GSK-872 decreases the RIPK3-mediated necroptosis and subsequent cytoplasmic translocation and expression of HMGB1, as well as ameliorates brain edema and neurological deficits in early brain injury .

HY-101872A

GSK-872 hydrochloride Maximum Cited Publications 64 Publications Verification	RIP kinase	Inflammation/Immunology
GSK-872 hydrochloride is a RIPK3 inhibitor, which binds RIP3 kinase domain with an IC₅₀ of 1.8 nM, and inhibits kinase activity with an IC₅₀ of 1.3 nM. GSK-872 hydrochloride decreases the RIPK3-mediated necroptosis and subsequent cytoplasmic translocation and expression of HMGB1, as well as ameliorates brain edema and neurological deficits in early brain injury .

HY-B0581R

Dexrazoxane (Standard)	Ferroptosis Apoptosis	Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
Dexrazoxane (Standard) is the analytical standard of Dexrazoxane. This product is intended for research and analytical applications. Dexrazoxane, as an intracellular iron chelating agent, reduces the formation of superoxide radicals and has cardioprotective, anti-inflammatory, antioxidant, anti-tumor and neuroprotective activities. Dexrazoxane inhibits ferroptosis of H9c2 cells by inhibiting HMGB1. Dexrazoxane induces DNA damage and apoptosis in human fibrosarcoma cells .

HY-Y1362R

Ethyl pyruvate (Standard)	Autophagy Apoptosis Pyroptosis NF-κB	Inflammation/Immunology Cancer
Ethyl pyruvate (Standard) is the analytical standard of Ethyl pyruvate. This product is intended for research and analytical applications. Ethyl pyruvate is a simple derivative of the endogenous metabolite pyruvate. Ethyl pyruvate is an HMGB1 release inhibitor. Ethyl pyruvate can induce apoptosis by autophagy. Ethyl pyruvate has anti-inflammatory, antioxidant and anti-tumor activity. Ethyl pyruvate can be used in the study of neurodegenerative diseases such as Alzheimer's and Parkinson's disease .

HY-N2055

Kaempferol 3-O-sophoroside	Toll-like Receptor (TLR) NF-κB TNF Receptor AMPK	Neurological Disease Inflammation/Immunology
Kaempferol 3-O-sophoroside is an orally active derivative of Kaempferol. It exhibits anti-inflammatory, analgesic, and antidepressant effects. Kaempferol 3-O-sophoroside is an inhibitor of the cell surface receptor toll-like receptor (TLR) 2/4 for High mobility group box 1 (HMGB1), and it also exerts anti-inflammatory effects by blocking the activation of NF-κB expression and the production of TNF-α. Kaempferol 3-O-sophoroside promotes the production of brain-derived neurotrophic factor (BDNF) and enhances autophagy by binding to AMP-activated protein kinase (AMPK), thereby exerting antidepressant effects. Kaempferol 3-O-sophoroside holds promise for research in the fields of inflammation and neurodegenerative diseases .

HY-168650

ROCK/HDAC-IN-1	ROCK HDAC	Inflammation/Immunology Cancer
ROCK/HDAC-IN-1 (Compound 10h) is an orally active ROCK/HDAC inhibitor. ROCK/HDAC-IN-1 inhibits ROCK1/2 (IC₅₀: 254.9 nM, 58.18 nM) and HDAC1/2/3/6/8 (IC₅₀: 9.09, 8.03, 6.26, 0.41, 7.69 nM). ROCK/HDAC-IN-1 stimulates the activation of DAMPs, specifically Calreticulin (CRT) exposure and HMGB1 release, indicating that it is a potential ICD inducer.. ROCK/HDAC-IN-1 has antiproliferative activity against breast cancer cells (IC₅₀: 0.37 μM for MDA-MB-231 cell), and inhibits tumor growth and activates T cells without apparent toxicity .

HY-19421

Orazamide	Bacterial	Inflammation/Immunology
Orazamide is an AICA orotate. Orazamide can prevent anti-TB drug-induced liver damage by downregulating the protein expression of *HMGB 1* and RAGE in liver tissue and inhibiting the secretion of inflammatory factors. Orazamide can be used in research on hepatitis and liver cirrhosis .

Cat. No.	Product Name	Target	Research Area

HY-P2268

RAGE antagonist peptide 2 Publications Verification	Amyloid-β	Inflammation/Immunology Cancer
RAGE antagonist peptide is an advanced glycation end products (RAGE) antagonist. RAGE antagonist peptide prevents RAGE from binding with several of its most important ligands, including HMGB-1, S100P, and S100A4. RAGE antagonist peptide (RAP) possesses anti-tumor and anti-inflammatory activities .

HY-P2268A

RAGE antagonist peptide TFA 2 Publications Verification	Amyloid-β	Inflammation/Immunology Cancer
RAGE antagonist peptide TFA is an advanced glycation end products (RAGE) antagonist. RAGE antagonist peptide TFA prevents RAGE from binding with several of its most important ligands, including HMGB-1, S100P, and S100A4. RAGE antagonist peptide TFA possesses anti-tumor and anti-inflammatory activities .

HY-P10321

HBP08	CXCR	Inflammation/Immunology
HBP08 is a selective inhibitor of *CXCL12/HMGB1* interaction. HBP08 has a high affinity for HMGB1 (K_d=0.8 μM). HBP08 inhibits CXCL12-mediated cell migration .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N0184

Glycyrrhizic acid 25+ Cited Publications Glycyrrhizin	Triterpenes Structural Classification Classification of Application Fields Leguminosae Terpenoids Source classification Metabolic Disease Plants Glycyrrhiza uralensis Fisch. Disease Research Fields Sweeteners Food Research	Virus Protease
Glycyrrhizic acid is a triterpenoid saponinl, acting as a direct *HMGB1* antagonist, with anti-tumor, anti-diabetic activities.

HY-N0184A

Dipotassium glycyrrhizinate 25+ Cited Publications Glycyrrhizic acid dipotassium; Dipotassium glycyrrhizate	Triterpenes Structural Classification Classification of Application Fields Leguminosae Terpenoids Source classification Plants Inflammation/Immunology Disease Research Fields Glycyrrhiza uralensis Fisch.	Virus Protease
Dipotassium glycyrrhizinate is a *HMGB1* inhibitor, inhibits atopic dermatitis-related gene expression with anti-anti-inflammatory activity .

HY-N2055

Kaempferol 3-O-sophoroside	Panax ginseng C. A. Meyer Flavonols Structural Classification Classification of Application Fields Source classification Plants Flavonoids other families Phenols Polyphenols Inflammation/Immunology Disease Research Fields Araliaceae	Toll-like Receptor (TLR) NF-κB TNF Receptor AMPK
Kaempferol 3-O-sophoroside is an orally active derivative of Kaempferol. It exhibits anti-inflammatory, analgesic, and antidepressant effects. Kaempferol 3-O-sophoroside is an inhibitor of the cell surface receptor toll-like receptor (TLR) 2/4 for High mobility group box 1 (HMGB1), and it also exerts anti-inflammatory effects by blocking the activation of NF-κB expression and the production of TNF-α. Kaempferol 3-O-sophoroside promotes the production of brain-derived neurotrophic factor (BDNF) and enhances autophagy by binding to AMP-activated protein kinase (AMPK), thereby exerting antidepressant effects. Kaempferol 3-O-sophoroside holds promise for research in the fields of inflammation and neurodegenerative diseases .

HY-N0184R

Glycyrrhizic acid (Standard)	Triterpenes Structural Classification Leguminosae Terpenoids Source classification Plants Glycyrrhiza uralensis Fisch.	Virus Protease
Glycyrrhizic acid (Standard) is the analytical standard of Glycyrrhizic acid. This product is intended for research and analytical applications. Glycyrrhizic acid is a triterpenoid saponinl, acting as a direct *HMGB1* antagonist, with anti-tumor, anti-diabetic activities.

HY-N0184AR

Dipotassium glycyrrhizinate (Standard)	Triterpenes Structural Classification Leguminosae Terpenoids Source classification Plants Glycyrrhiza uralensis Fisch.	Virus Protease
Dipotassium glycyrrhizinate (Standard) is the analytical standard of Dipotassium glycyrrhizinate. This product is intended for research and analytical applications. Dipotassium glycyrrhizinate is a HMGB1 inhibitor, inhibits atopic dermatitis-related gene expression with anti-anti-inflammatory activity .

HY-N9587

Tricin 7-O-β-D-glucopyranoside	Structural Classification Flavonoids Flavones Source classification Crassulaceae Sedum sarmentosum Bunge Plants	Apoptosis
Tricin 7-O-β-D-glucopyranoside is a potent and orally active neuroprotective agent. Tricin 7-O-β-D-glucopyranoside induces Apoptosis. Tricin 7-O-β-D-glucopyranoside decreases the expression of TNF-α induced phosphor-κB-α, phosphor-NF-κB, HMGB1 .

Species:	Human (8) Mouse (3)
Tag:	His (7) Tag Free (1) Fc (3)
Source:	HEK293 (6) E. coli (5)

Cat. No.	Compare	Product Name	Species	Source

HY-P78139

	HMGB1/HMG-1 Protein, Human (Biotinylated, HEK293, His) HMGB1; HMG1; HMG3; SBP-1; HMG-1	Human	HEK293
	The multifunctional and redox-sensitive HMGB1/HMG-1 protein plays multiple roles in cellular compartments. In the nucleus, it serves as a major chromatin-associated non-histone protein involved in key processes such as replication, transcription, chromatin remodeling, V(D)J recombination, DNA repair, and genome stability. HMGB1/HMG-1 Protein, Human (Biotinylated, HEK293, His) is the recombinant human-derived HMGB1/HMG-1 protein, expressed by HEK293 , with C-His labeled tag. The total length of HMGB1/HMG-1 Protein, Human (Biotinylated, HEK293, His) is 215 a.a., with molecular weight of 30-36 kDa.

HY-P73102

	HMGB1/HMG-1 Protein, Human (HEK293, Fc) 2 Publications Verification High mobility group protein B1; HMG-1; HMGB1; HMG1	Human	HEK293
	The multifunctional and redox-sensitive HMGB1/HMG-1 protein plays multiple roles in cellular compartments. In the nucleus, it serves as a major chromatin-associated non-histone protein involved in key processes such as replication, transcription, chromatin remodeling, V(D)J recombination, DNA repair, and genome stability. HMGB1/HMG-1 Protein, Human (HEK293, Fc) is the recombinant human-derived HMGB1/HMG-1 protein, expressed by HEK293 , with N-hFc labeled tag. The total length of HMGB1/HMG-1 Protein, Human (HEK293, Fc) is 215 a.a..

HY-P73104A

	HMGB1/HMG-1 Protein, Mouse (HEK293, Fc) 2 Publications Verification High mobility group protein B1; HMG-1; HMGB1; HMG1	Mouse	HEK293
	HMGB1, or high mobility group box 1, is a protein that plays a role in various cellular processes. It has different functionalities depending on its redox state and location within the cell. HMGB1/HMG-1 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived HMGB1/HMG-1 protein, expressed by HEK293 , with N-hFc labeled tag. The total length of HMGB1/HMG-1 Protein, Mouse (HEK293, Fc) is 215 a.a., with molecular weight of 57-59.24 kDa.

HY-P73103

	HMGB1/HMG-1 Protein, Human (102a.a, His) High mobility group protein B1; HMG-1; HMGB1; HMG1	Human	E. coli
	The multifunctional and redox-sensitive HMGB1/HMG-1 protein plays multiple roles in cellular compartments. In the nucleus, it serves as a major chromatin-associated non-histone protein involved in key processes such as replication, transcription, chromatin remodeling, V(D)J recombination, DNA repair, and genome stability. HMGB1/HMG-1 Protein, Human (102a.a, His) is the recombinant human-derived HMGB1/HMG-1 protein, expressed by E. coli , with N-His, N-6*His labeled tag. The total length of HMGB1/HMG-1 Protein, Human (102a.a, His) is 102 a.a., with molecular weight of ~15 kDa.

HY-P73104

	HMGB1/HMG-1 Protein, Mouse (HEK293, Fc, solution) 1 Publications Verification High mobility group protein B1; HMG-1; HMGB1; HMG1	Mouse	HEK293
	HMGB1, or high mobility group box 1, is a protein that plays a role in various cellular processes. It has different functionalities depending on its redox state and location within the cell. HMGB1/HMG-1 Protein, Mouse (HEK293, Fc, solution) is the recombinant mouse-derived HMGB1/HMG-1 protein, expressed by HEK293 , with N-hFc labeled tag. The total length of HMGB1/HMG-1 Protein, Mouse (HEK293, Fc, solution) is 215 a.a., with molecular weight of ~57 kDa.

HY-P72797

	HMGB1/HMG-1 Protein, Human (His) 1 Publications Verification High mobility group protein B1; High mobility group protein 1; HMG-1; HMGB1	Human	E. coli
	The multifunctional and redox-sensitive HMGB1/HMG-1 protein plays multiple roles in cellular compartments. In the nucleus, it serves as a major chromatin-associated non-histone protein involved in key processes such as replication, transcription, chromatin remodeling, V(D)J recombination, DNA repair, and genome stability. HMGB1/HMG-1 Protein, Human (His) is the recombinant human-derived HMGB1/HMG-1 protein, expressed by E. coli , with C-His labeled tag.

HY-P70570

	HMGB1/HMG-1 Protein, Human 1 Publications Verification High Mobility Group Protein B1; High Mobility Group Protein 1; HMG-1; HMGB1; HMG1	Human	E. coli
	The multifunctional and redox-sensitive HMGB1/HMG-1 protein plays multiple roles in cellular compartments. In the nucleus, it serves as a major chromatin-associated non-histone protein involved in key processes such as replication, transcription, chromatin remodeling, V(D)J recombination, DNA repair, and genome stability. HMGB1/HMG-1 Protein, Human is the recombinant human-derived HMGB1/HMG-1 protein, expressed by E. coli , with tag free. The total length of HMGB1/HMG-1 Protein, Human is 89 a.a., with molecular weight of ~14.35 kDa.

HY-P70274

	HMGB1/HMG-1 Protein, Human (HEK293, His, solution) 1 Publications Verification rHuHigh mobility group protein B1/HMGB1, His; High Mobility Group Protein B1; High Mobility Group Protein 1; HMG-1; HMGB1; HMG1	Human	HEK293
	The multifunctional and redox-sensitive HMGB1/HMG-1 protein plays multiple roles in cellular compartments. In the nucleus, it serves as a major chromatin-associated non-histone protein involved in key processes such as replication, transcription, chromatin remodeling, V(D)J recombination, DNA repair, and genome stability. HMGB1/HMG-1 Protein, Human (HEK293, His, solution) is the recombinant human-derived HMGB1/HMG-1 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P70274A

	HMGB1/HMG-1 Protein, Human (HEK293, C-His) rHuHigh mobility group protein B1/HMGB1, His; High Mobility Group Protein B1; High Mobility Group Protein 1; HMG-1; HMGB1; HMG1	Human	HEK293
	The multifunctional and redox-sensitive HMGB1/HMG-1 protein plays multiple roles in cellular compartments. In the nucleus, it serves as a major chromatin-associated non-histone protein involved in key processes such as replication, transcription, chromatin remodeling, V(D)J recombination, DNA repair, and genome stability. HMGB1/HMG-1 Protein, Human (HEK293, His) is the recombinant human-derived HMGB1/HMG-1 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P72797AF

	*Animal-Free HMGB1/HMG-1 Protein, Human (His)* High Mobility Group Protein B1; High Mobility Group Protein 1; HMG-1; HMGB1; HMG1	Human	E. coli
	The multifunctional and redox-sensitive HMGB1/HMG-1 protein plays multiple roles in cellular compartments. In the nucleus, it serves as a major chromatin-associated non-histone protein involved in key processes such as replication, transcription, chromatin remodeling, V(D)J recombination, DNA repair, and genome stability. Animal-Free HMGB1/HMG-1 Protein, Human (His) is the recombinant human-derived animal-FreeHMGB1/HMG-1 protein, expressed by E. coli , with C-His, C-His labeled tag. The total length of Animal-Free HMGB1/HMG-1 Protein, Human (His) is 215 a.a., with molecular weight of ~25.70 kDa.

HY-P700182AF

	*Animal-Free HMGB1/HMG-1 Protein, Mouse (His)* HMG-1; Hmg1; SBP; SBP-1; amph; p3; p30	Mouse	E. coli
	HMGB1, or high mobility group box 1, is a protein that plays a role in various cellular processes. It has different functionalities depending on its redox state and location within the cell. Animal-Free HMGB1/HMG-1 Protein, Mouse (His) is the recombinant mouse-derived animal-FreeHMGB1/HMG-1 protein, expressed by E. coli , with C-His labeled tag. The total length of Animal-Free HMGB1/HMG-1 Protein, Mouse (His) is 215 a.a., with molecular weight of ~25.56 kDa.

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HY-N0184S

Glycyrrhizic acid-d3
Glycyrrhizic acid-d₃ (Glycyrrhizin-d₃) is deuterium labeled Glycyrrhizic acid. Glycyrrhizic acid is a triterpenoid saponinl, acting as a direct *HMGB1* antagonist, with anti-tumor, anti-diabetic activities .

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HY-P80183

	HMGB1 Antibody	WB, ICC/IF, IHC-P, FC	Human, Mouse, Rat
	HMGB1 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 25 kDa, targeting to HMGB1. It can be used for WB,ICC/IF,IHC-P,FC assays with tag free, in the background of Human, Mouse, Rat.

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HMGB 1

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