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Results for "

RAC1

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Akt (1) Apoptosis (11) Biochemical Assay Reagents (9) Casein Kinase (2) CDK (1) DOCK (1) Endogenous Metabolite (4) ERK (1) FAK (1) Integrin (1) Isotope-Labeled Compounds (1) Liposome (1) MMP (1) NADPH Oxidase (1) Phosphatase (1) PI3K (1) Piezo Channel (1) Potassium Channel (1) Ras (23) Reactive Oxygen Species (1) Small Interfering RNA (siRNA) (1) Src (1) Taste Receptor (1)
By Research Areas:	Cancer (20) Cardiovascular Disease (2) Infection (1) Inflammation/Immunology (9) Metabolic Disease (1) Neurological Disease (3)
Oligonucleotides:	Pre-designed siRNA Sets (1) Phospholipids (1) siRNAs (1)

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P1382A

Rac1 Inhibitor W56 TFA	Ras	Cancer
Rac1 Inhibitor W56 TFA is a peptide containing residues 45-60 of Rac1. Rac1 Inhibitor W56 TFA inhibits Rac1 interaction with guanine nucleotide exchange factors TrioN, GEF-H1, and Tiam ^[1].

HY-158304

Rac1-IN-4	Ras	Cancer
Rac1-IN-4 (Cas: 2924486-45-1) is a *Rac1* inhibitor ^[1].

HY-156668

Rac1-IN-3	Ras	Cardiovascular Disease
Rac1-IN-3 (Compound 2) is a *Rac1* inhibitor with an IC₅₀ of 46.1 μM ^[1].

HY-136383

AZA1 1 Publications Verification RAC1/Cdc42-IN-1	Ras Apoptosis	Cancer
AZA1 is a potent dual inhibitor of *Rac1* and Cdc42. AZA1 induces prostate cancer cells apoptosis and inhibits prostate cancer cells proliferation, migration and invasion ^[1] .

HY-107501

*(Rac)-1-Oleoyl lysophosphatidic acid sodium* (RAC)-1-Oleoyl-sn-glycero-3-phosphate sodium; (RAC)-1-Oleoyl-LPA sodium	Others	Neurological Disease
(Rac)-1-Oleoyl lysophosphatidic acid ((Rac)-1-Oleoyl-sn-glycero-3-phosphate) sodium is the racemic isomer of 1-Oleoyl lysophosphatidic acid sodium (HY-107614) ^[1].

HY-P1382

Rac1 Inhibitor W56	Ras	Cancer
Rac1 Inhibitor W56 is a peptide containing residues 45-60 of Rac1. Rac1 Inhibitor W56 inhibits Rac1 interaction with guanine nucleotide exchange factors TrioN, GEF-H1, and Tiam ^[1].

HY-RS11591

RAC1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
RAC1 Human Pre-designed siRNA Set A contains three designed siRNAs for RAC1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

RAC1 Human Pre-designed siRNA Set A RAC1 Human Pre-designed siRNA Set A

HY-W777103

*(Rac)-1-Oleoyl-3-linoleoyl-glycerol*	Biochemical Assay Reagents
(Rac)-1-Oleoyl-3-linoleoyl-glycerol is a kind of biochemical reagent.

HY-167569

*(Rac)-1-Palmitoyl-glycero-3-phosphocholine*	Biochemical Assay Reagents
(Rac)-1-Palmitoyl-glycero-3-phosphocholine is a kind of biochemical reagent.

HY-W127415

rac-1-Stearoyl-3-chloropropanediol	Biochemical Assay Reagents	Others
rac-1-Stearoyl-3-chloropropanediol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W777682

*(Rac)-1-Linoleoyl-2,3-isopropylidene-glycerol*	Biochemical Assay Reagents
(Rac)-1-Linoleoyl-2,3-isopropylidene-glycerol is a kind of biochemical reagent.

HY-W749756

rac-1,2-Distearoyl-3-chloropropanediol-13C3	Isotope-Labeled Compounds	Others
rac-1,2-Distearoyl-3-chloropropanediol- ¹³C₃ is ¹³C labeled rac-1,2-Distearoyl-3-chloropropanediol ^[1].

HY-W013060

*(Rac)-1,2-Dilinoleoyl-3-palmitoyl-glycerol*	Biochemical Assay Reagents
(Rac)-1,2-Dilinoleoyl-3-palmitoyl-glycerol is a kind of biochemical reagent.

HY-112307A

*(Rac)-1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol sodium*	Liposome	Others
(Rac)-1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol (sodium) is an anionic phospholipid, can be used for drug delivery and the synthesis of liposomes ^[1].

HY-W127570

rac-1,2-Distearoyl-3-chloropropanediol 3-Chloro-1,2-propanediol Distearate	Biochemical Assay Reagents	Others
rac-1,2-Distearoyl-3-chloropropanediol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W127363

*(Rac)-1,2-Dihexadecylglycerol*	Biochemical Assay Reagents	Others
1,2-O-Dihexadecyl-rac-glycerol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W127391

1,2-Dilaurin (RAC)-1,2-Didodecanoylglycerol	Biochemical Assay Reagents	Others
1,2-Dilaurin is a diacylglycerol containing lauric acid at the sn-1 and sn-2 positions. It has been used as an internal standard for the quantification of diglycerides in rat desheathed sciatic nerves. [1] Monomolecular films containing 1,2-dilauroyl-rac-glycerol have been used as substrates to measure surface pressure and the effect of pancreatic procolipase and colipase on porcine pancreatic lipase activity. [2] References: [1]. Zhu, X. and Eichberg, J. 1,2-Diacylglycerol content and its arachidonyl-containing molecular species are reduced in the sciatic nerve of streptozotocin-induced diabetic rats. J. Neurochemistry. 55(3), 1087-1090 (1990).[2]. Wieloch, T., Borgstr m, B., Piéroni, G. et al. Porcine trypsinogen and its trypsin-activated form: lipid binding and lipase activation on monomolecular membranes. FEBS Express. 128(2), 217-220 (1981).

HY-W778471

rac-1-Linoleoyl-3-linolenoyl-propanetriol DG(18:2/0:0/18:3); 1-Linolein-3-α-Linolenin; 1-Linolein-3-Linolenin	Endogenous Metabolite	Metabolic Disease
1-Linoleoyl-3-α-linolenoyl-rac-glycerol is a diacylglycerol that contains linoleic acid (HY-N0729) at the sn-1 position and α-linolenic acid (HY-N0728) at the sn-3 position. It has been found in olive oil subjected to lipase-catalyzed glycerolysis with immobilized lipase B from C. antarctica.

HY-102078

ZINC69391 1 Publications Verification	Ras Apoptosis	Cancer
ZINC69391, a specific *Rac1* inhibitor, interferes with Rac1-GEF interaction by masking Trp56 residue on Rac1 surface. ZINC69391 interferes with the interaction of Rac1 with Dock180 and reduces Rac1-GTP levels. ZINC69391 induces apoptosis, and shows antiproliferative and antimetastatic effects ^[1] .

HY-12810

EHop-016 4 Publications Verification	Ras	Cancer
EHop-016 is a potent and selective **Rac GTPase Rac1 and Rac3 inhibitor. EHop-016 inhibits Rac1 activity with an IC₅₀** of 1.1 μM in MDA-MB-435 cells. EHop-016 inhibits Vav2 interaction with Rac, Rac-activated PAK1, lamellipodia formation, and cell migration ^[1] .

HY-110100

CPYPP 2 Publications Verification	DOCK	Inflammation/Immunology
CPYPP is a DOCK2-Rac1 interaction inhibitor. CPYPP binds to DOCK2 DHR-2 domain and inhibits the guanine nucleotide exchange factor (GEF) activity of DOCK2 ^DHR-2 for Rac1 in a dose-dependent manner with an IC₅₀ of 22.8 μM. CPYPP also inhibits DOCK180 and DOCK5 and less inhibits DOCK9 ^[1].

HY-124306

ML-099 2 Publications Verification CID-888706	Ras	Cancer
ML-099 (CID-888706) is a pan Ras-related GTPases activator that can activate *Rac1, cell division cycle 42, Ras, Rab7, and Rab-2A* ^[1].

HY-118208

ML-097 1 Publications Verification CID-2160985	Ras	Cancer
ML-097 (CID-2160985) is a pan Ras-related GTPases activator that can activate *Rac1, cell division cycle 42, Ras, and Rab7* ^[1].

HY-115376

Z62954982 ZINC08010136	Ras	Inflammation/Immunology
Z62954982 (ZINC08010136) is a potent, selective and?cell-permeable *Rac1* (IC₅₀=12 μM) inhibitor that is 4 times more effective than NSC23766 (HY-15723A) (IC₅₀=50 μM). Z62954982?disrupts the Rac1/Tiam1 complex and decreases cytoplasmic levels of active Rac1 (GTP-bound Rac1), without affecting the activity of other Rho GTPases (such as Cdc42 or RhoA) ^[1] .

HY-15723A

NSC 23766 trihydrochloride 30+ Cited Publications	Ras Apoptosis	Cancer
NSC 23766 trihydrochloride is an inhibitor of *Rac1* activation.

HY-104064

1A-116 5 Publications Verification	Ras Apoptosis	Cancer
1A-116, a potent *Rac1* inhibitor, is specific for W56 residues, can prevent EGF-induced *Rac1* activation and block *Rac1-P-Rex1* interaction. 1A-116 can induce apoptosis and inhibit cell proliferation, migration and cycle progression in a concentration-dependent manner. 1A-116 also demonstrates a high antimetastatic activity in vivo ^[1] .

HY-119576

Phox-I2	NADPH Oxidase Reactive Oxygen Species	Inflammation/Immunology
Phox-I2 is a selective inhibitor of p67 ^phox-Rac1 interaction, binds to p67 ^phox with high affinity with a K_d of ~150 nM. Phox-I2 is a NADPH oxidase 2 (NOX2) inhibitor and inhibits reactive oxygen species (ROS) production ^[1].

HY-134243

6-T-GDP 6-Thioguanosine 5'-diphosphate	Endogenous Metabolite Ras	Inflammation/Immunology
6-T-GDP (6-Thioguanosine 5'-diphosphate) is a metabolite of azathioprine. 6-T-GDP can reduce the transcription of inflammatory factors and the expression of cell adhesion molecules by inhibiting the activity of *Rac1*, thereby inhibiting the migration of leukocytes and the occurrence of tissue inflammation ^[1].

HY-U00145

Digeranyl bisphosphonate DGBP	Ras	Inflammation/Immunology
Digeranyl bisphosphonate (DGBP) is a potent geranylgeranylpyrophosphate (GGPP) synthase inhibitor, which inhibits geranylgeranylation of Rac1.

HY-50733A

CX-5011	Casein Kinase Ras Apoptosis	Cancer
CX-5011 is a CK2 inhibitor. CX-5011 also induces *Rac1* activation. CX-5011 induces apoptosis and induces cancer cell death ^[1] .

HY-152095

PPI-GIT1/β-Pix interaction-IN-1	Ras	Cancer
PPI-GIT1/β-Pix interaction-IN-1 is a potent and orally active GIT1/β-Pix protein-protein interaction (PPI) inhibitor with a K_D value of 7.7 µM. PPI-GIT1/β-Pix interaction-IN-1 disrupts the GIT/PIX interaction can impact the activation of the downstream Rho GTPase Rac1 and Cdc42. PPI-GIT1/β-Pix interaction-IN-1 inhibits metastasis of gastric cancer ^[1].

HY-N0710

alpha-Cyperone 2 Publications Verification α-Cyperone; (+)-α-Cyperone	Endogenous Metabolite	Inflammation/Immunology
alpha-Cyperone (α-Cyperone) is associated with the down-regulation of COX-2, IL-6, Nck-2, Cdc42 and Rac1, resulting in reduction of inflammation, which would be highly beneficial for treatment of inflammatory diseases such as AD.

HY-15031

l-Naproxen (R)-Naproxen	Others	Cancer
l-Naproxen ((R)-Naproxen) is an enantiomer of (S)-Naproxen. l-Naproxen can inhibit Cdc42 and *Rac1* (EC₅₀=96 μM and 212 μM, respectively), and show anti-tumor activity. l-Naproxen is a nonsteroidal antiinflammatory agent (NSAID) ^[1] .

HY-50733

CX-5011 free base	Apoptosis Casein Kinase Ras	Cancer
CX-5011 free base is a potent CK2 inhibitor. CX-5011 free base also is a *Rac-1* activator. CX-5011 free base induces methuosis and promotes macropinocytosis. CX-5011 free base induces apoptosis. CX-5011 free base decreases the expression of rpS6 phosphorylation ^[1] .

HY-120213

YH-306	FAK Src PI3K MMP Apoptosis	Cancer
YH-306 is an antitumor agent. YH-306 suppresses colorectal tumour growth and metastasis via FAK pathway. YH-306 significantly inhibits the migration and invasion of colorectal cancer cells. YH-306 potently suppresses uninhibited proliferation and induces cell apoptosis. YH-306 suppresses the activation of FAK, c-Src, paxillin, and PI3K, Rac1 and the expression of MMP2 and MMP9. YH-306 also inhibita actin-related protein (Arp2/3) complex-mediated actin polymerization ^[1].

HY-120229

GGTI-2147	Others	Neurological Disease
GGTI-2147 is a potent GGTase I inhibitor. GGTI-2147 blocks geranyl-geranylation of Rap1A and reduces the activity of Rac1 (one of substrates for GGTI) and ameliorates the OGD/R-induced neuronal apoptosis.GGTI-2147 can be used for neurodevelopmental disorders research, such as autism, depression, and schizophrenia ^[1].

HY-18723

Yoda 1 Maximum Cited Publications 38 Publications Verification	Piezo Channel Akt ERK Potassium Channel	Cardiovascular Disease
Yoda 1 is a potent and selective *Piezo1* agonist. Yoda 1 activates purified Piezo1 channels. Yoda 1 potently inhibits macropinocytosis induced by epidermal growth factor (EGF). Yoda 1 enhances Ca ²⁺ influx followed by activation of the calcium-activated potassium channel *KCa3.1* and inhibition of *Rac1* activation ^[1] .

HY-113849

MLS-573151 1 Publications Verification MLS000573151	Ras	Inflammation/Immunology
MLS-573151 (MLS000573151) is a selective GTPase Cdc42 inhibitor with an EC₅₀ of 2 μM. MLS-573151 is inactive against other GTPases family members, such as Rab2, Rab7, H-Ras, Rac1, Rac 2 and RhoA wild-type. MLS-573151 acts by blocking the binding of GTP to Cdc42 ^[1] .

HY-P10038

mP6 Myr-FEEERA-OH	Integrin	Infection
mP6 (Myr-FEEERA-OH) is a myristoylated peptide. mP6 inhibits the interaction of Gα₁₃ with integrin β₃ without disrupting talin-dependent integrin function. mP6 can block the GTP usage of Rac1, Rap1, and Rab7, effectively inhibiting the infection of CHO-A24 cells ^[1].

HY-N0710R

alpha-Cyperone (Standard)	Endogenous Metabolite	Inflammation/Immunology
alpha-Cyperone (Standard) is the analytical standard of alpha-Cyperone. This product is intended for research and analytical applications. alpha-Cyperone (α-Cyperone) is associated with the down-regulation of COX-2, IL-6, Nck-2, Cdc42 and Rac1, resulting in reduction of inflammation, which would be highly beneficial for treatment of inflammatory diseases such as AD.

HY-12646

Rhosin hydrochloride 20+ Cited Publications	Ras Apoptosis	Cancer
Rhosin hydrochloride is a potent, specific RhoA subfamily Rho GTPases inhibitor. Rhosin hydrochloride specifically binds to RhoA to inhibit RhoA-GEF interaction with a K_d of ~ 0.4 uM, and does not interact with Cdc42 or Rac1, nor the GEF, LARG. Rhosin hydrochloride induces cell apoptosis ^[1] . Rhosin hydrochloride promotes stress resiliency through enhancing D1-MSN plasticity and reducing hyperexcitability .

HY-12646A

Rhosin	Ras Apoptosis	Cancer
Rhosin is a potent, specific RhoA subfamily Rho GTPases inhibitor, which specifically binds to RhoA to inhibit RhoA-GEF interaction with a K_d of ~ 0.4 uM, and does not interact with Cdc42 or Rac1, nor the GEF, LARG. Rhosin induces cell apoptosis ^[1] . Rhosin promotes stress resiliency through enhancing D1-MSN plasticity and reducing hyperexcitability .

HY-12755

ML141 20+ Cited Publications CID-2950007	Ras Apoptosis	Cancer
ML141 (CID-2950007) is a potent, allosteric, selective and reversible non-competitive inhibitor of Cdc42 GTPase. ML141 inhibits Cdc42 wild type and Cdc42 Q61L mutant with EC₅₀s of 2.1 and 2.6 μM, respectively. ML141 shows low micromolar potency and selectivity against other members of the Rho family of GTPases (Rac1, Rab2, Rab7). ML141 do not show cytotoxicity in multiple cell lines ^[1] .

HY-16659

EHT 1864 10+ Cited Publications	Ras	Neurological Disease Cancer
EHT 1864 is an inhibitor of Rac family small GTPases. EHT 1864 directly binds and impairs the ability of this small GTPase to engage critical downstream effectors required for growth transformation. The K_d values are 40, 50, 60, and 230 nM for Rac1, Rac1b, Rac2 and Rac3, respectively. EHT 1864 also potently inhibits other Rac-dependent transformation processes, Tiam1- and Ras-mediated growth transformation. EHT 1864 prevents Aβ 40 and Aβ 42 production in vivo. EHT 1864 dependently suppresses the release of migrasomes from podocytes induced by LPS, PAN, or HG ^[1] .

HY-100047

Nα,Nα-Bis(carboxymethyl)-L-lysine	Taste Receptor	Others
Nα,Nα-Bis(carboxymethyl)-L-lysine is a competitive inhibitor of bitter taste receptor 4, with an IC₅₀ of 59 nM. Nα,Nα-Bis(carboxymethyl)-L-lysine can be used in bitter receptors related study ^[1] .

HY-112842

MBQ-167 5 Publications Verification	Ras CDK	Cancer
MBQ-167 is a dual *Rac/Cdc42* inhibitor, with IC₅₀s of 103 nM for Rac 1/2/3 and 78 nM for Cdc42 in MDA-MB-231 cells, respectively.

HY-133146

DJ001	Phosphatase Apoptosis	Inflammation/Immunology
DJ001 is a highly specific, selective and non-competitive protein tyrosine phosphatase-σ (PTPσ) inhibitor with an IC₅₀ of 1.43 μM. DJ001 displays no inhibitory activity against other phosphatases, with only modest inhibitory activity against Protein Phosphatase 5. DJ001 promotes promote hematopoietic stem cell regeneration ^[1].

HY-W127550

*1,2-Dipalmitoyl-sn-glycero-3-phospho-rac-(1-glycerol) sodium* PG(16:0/16:0)	Biochemical Assay Reagents	Others
rac-DPPG sodium is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Cat. No.	Product Name	Type

HY-112307A

*(Rac)-1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol sodium*	Drug Delivery
(Rac)-1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol (sodium) is an anionic phospholipid, can be used for drug delivery and the synthesis of liposomes ^[1].

HY-W127391

1,2-Dilaurin

(RAC)-1,2-Didodecanoylglycerol

Drug Delivery

1,2-Dilaurin is a diacylglycerol containing lauric acid at the sn-1 and sn-2 positions. It has been used as an internal standard for the quantification of diglycerides in rat desheathed sciatic nerves. [1] Monomolecular films containing 1,2-dilauroyl-rac-glycerol have been used as substrates to measure surface pressure and the effect of pancreatic procolipase and colipase on porcine pancreatic lipase activity. [2] References: [1]. Zhu, X. and Eichberg, J. 1,2-Diacylglycerol content and its arachidonyl-containing molecular species are reduced in the sciatic nerve of streptozotocin-induced diabetic rats. J. Neurochemistry. 55(3), 1087-1090 (1990).[2]. Wieloch, T., Borgstr m, B., Piéroni, G. et al. Porcine trypsinogen and its trypsin-activated form: lipid binding and lipase activation on monomolecular membranes. FEBS Express. 128(2), 217-220 (1981).

HY-W777103

*(Rac)-1-Oleoyl-3-linoleoyl-glycerol*	Drug Delivery
(Rac)-1-Oleoyl-3-linoleoyl-glycerol is a kind of biochemical reagent.

HY-167569

*(Rac)-1-Palmitoyl-glycero-3-phosphocholine*	Drug Delivery
(Rac)-1-Palmitoyl-glycero-3-phosphocholine is a kind of biochemical reagent.

HY-W127415

rac-1-Stearoyl-3-chloropropanediol	Drug Delivery
rac-1-Stearoyl-3-chloropropanediol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W777682

*(Rac)-1-Linoleoyl-2,3-isopropylidene-glycerol*	Drug Delivery
(Rac)-1-Linoleoyl-2,3-isopropylidene-glycerol is a kind of biochemical reagent.

HY-W013060

*(Rac)-1,2-Dilinoleoyl-3-palmitoyl-glycerol*	Drug Delivery
(Rac)-1,2-Dilinoleoyl-3-palmitoyl-glycerol is a kind of biochemical reagent.

HY-W127570

rac-1,2-Distearoyl-3-chloropropanediol 3-Chloro-1,2-propanediol Distearate	Drug Delivery
rac-1,2-Distearoyl-3-chloropropanediol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W127363

*(Rac)-1,2-Dihexadecylglycerol*	Drug Delivery
1,2-O-Dihexadecyl-rac-glycerol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W127550

*1,2-Dipalmitoyl-sn-glycero-3-phospho-rac-(1-glycerol) sodium* PG(16:0/16:0)	Drug Delivery
rac-DPPG sodium is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Cat. No.	Product Name	Target	Research Area

HY-P1382A

Rac1 Inhibitor W56 TFA	Ras	Cancer
Rac1 Inhibitor W56 TFA is a peptide containing residues 45-60 of Rac1. Rac1 Inhibitor W56 TFA inhibits Rac1 interaction with guanine nucleotide exchange factors TrioN, GEF-H1, and Tiam ^[1].

HY-100047

Nα,Nα-Bis(carboxymethyl)-L-lysine	Taste Receptor	Others
Nα,Nα-Bis(carboxymethyl)-L-lysine is a competitive inhibitor of bitter taste receptor 4, with an IC₅₀ of 59 nM. Nα,Nα-Bis(carboxymethyl)-L-lysine can be used in bitter receptors related study ^[1] .

HY-P1382

Rac1 Inhibitor W56	Ras	Cancer
Rac1 Inhibitor W56 is a peptide containing residues 45-60 of Rac1. Rac1 Inhibitor W56 inhibits Rac1 interaction with guanine nucleotide exchange factors TrioN, GEF-H1, and Tiam ^[1].

HY-P1383A

Rac1 Inhibitor F56, control peptide TFA	Peptides	Others
Rac1 Inhibitor F56, control peptide TFA is a peptide containing residues 45-60 of Rac1. Rac1 Inhibitor F56, control peptide TFA contains a Trp ⁵⁶ to Phe ⁵⁶ mutation. Rac1 Inhibitor F56, control peptide TFA has no effect on Rac1 interaction with its guanine nucleotide exchange factors (GEFs) ^[1].

HY-P1383

Rac1 Inhibitor F56, control peptide	Peptides	Others
Rac1 Inhibitor F56, control peptide is a peptide containing residues 45-60 of Rac1. Rac1 Inhibitor F56, control peptide contains a Trp ⁵⁶ to Phe ⁵⁶ mutation. Rac1 Inhibitor F56, control peptide has no effect on Rac1 interaction with its guanine nucleotide exchange factors (GEFs) ^[1].

HY-P10107

TAT-PAK18 R192A	Peptides	Others
TAT-PAK18 R192A is an inactive Tat-Pak peptide. TAT-PAK18 R192A does not have any effect in the translocation of Rac1 triggered by any of the interrogated proteins ^[1].

HY-P10038

mP6 Myr-FEEERA-OH	Integrin	Infection
mP6 (Myr-FEEERA-OH) is a myristoylated peptide. mP6 inhibits the interaction of Gα₁₃ with integrin β₃ without disrupting talin-dependent integrin function. mP6 can block the GTP usage of Rac1, Rap1, and Rab7, effectively inhibiting the infection of CHO-A24 cells ^[1].

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N0710

alpha-Cyperone 2 Publications Verification α-Cyperone; (+)-α-Cyperone	Structural Classification other families Classification of Application Fields Terpenoids Sesquiterpenes Source classification Plants Endogenous metabolite Inflammation/Immunology Disease Research Fields	Endogenous Metabolite
alpha-Cyperone (α-Cyperone) is associated with the down-regulation of COX-2, IL-6, Nck-2, Cdc42 and Rac1, resulting in reduction of inflammation, which would be highly beneficial for treatment of inflammatory diseases such as AD.

HY-N0710R

alpha-Cyperone (Standard)	Structural Classification other families Terpenoids Sesquiterpenes Source classification Plants Endogenous metabolite	Endogenous Metabolite
alpha-Cyperone (Standard) is the analytical standard of alpha-Cyperone. This product is intended for research and analytical applications. alpha-Cyperone (α-Cyperone) is associated with the down-regulation of COX-2, IL-6, Nck-2, Cdc42 and Rac1, resulting in reduction of inflammation, which would be highly beneficial for treatment of inflammatory diseases such as AD.

Species:	Human (3)
Tag:	Tag Free (1) GST (2)
Source:	Sf9 insect cells (2) E. coli (1)

Cat. No.	Compare	Product Name	Species	Source

HY-P74608

	RAC1 Protein, Human (sf9, GST) Ras-related C3 botulinum toxin substrate 1; p21-RAC1; RAC1; TC25; MIG5	Human	Sf9 insect cells
	The RAC1 protein is a plasma membrane-associated small GTPase that dynamically regulates multiple cellular responses by cycling between an active GTP-bound state and an inactive GDP-bound state. In its active form, RAC1 regulates processes such as secretory function, phagocytosis, cell polarization, neuronal activity, and growth factor-induced membrane ruffle formation. RAC1 Protein, Human (sf9, GST) is the recombinant human-derived RAC1 protein, expressed by Sf9 insect cells , with N-GST labeled tag. The total length of RAC1 Protein, Human (sf9, GST) is 189 a.a., with molecular weight of ~44 kDa.

HY-P702748

	PAK5 Protein, Human PAK5; p21 (RAC1) activated kinase 5; PAK7	Human	E. coli
	PAK5 Protein, Human is the recombinant human-derived PAK5, expressed by E. coli , with tag Free labeled tag. ,

HY-P702745

	PAK2 Protein, Human (sf9, GST) PAK2; p21 (RAC1) activated kinase 2; KNO2; PAK65; PAKgamma	Human	Sf9 insect cells
	PAK2 Protein, Human (sf9, GST) is the recombinant human-derived PAK2, expressed by Sf9 insect cells , with GST labeled tag. ,

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HY-W749756

rac-1,2-Distearoyl-3-chloropropanediol-13C3
rac-1,2-Distearoyl-3-chloropropanediol- ¹³C₃ is ¹³C labeled rac-1,2-Distearoyl-3-chloropropanediol ^[1].

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P82859

	*Phospho-Rac1/CDC42 (Ser71) Antibody (YA2604)* CDC42; CDC42Hs; G25K; TKS; MIG5; Ras like protein TC25	WB	Human
	Phospho-Rac1/CDC42 (Ser71) Antibody (YA2604) is a non-conjugated IgG antibody, targeting Phospho-Rac1/CDC42 (Ser71), with a predicted molecular weight of 21 kDa (observed band size: 24 kDa). Phospho-Rac1/CDC42 (Ser71) Antibody (YA2604) can be used for WB experiment in human background.

HY-P83545

	Rac Antibody (YA3290) Cell migration-inducing gene 5 protein; EN-7; GX; p21-RAC1; p21-RAC2; p21-RAC3; RAC1; RAC2; RAC3; TC25	WB	Human, Mouse, Rat
	Rac Antibody (YA3290) is a biotin-conjugated non-conjugated IgG antibody, targeting Rac, with a predicted molecular weight of 21 kDa. Rac Antibody (YA3290) can be used for WB experiment in human, mouse, rat background.