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Results for "

Ruthenium

" in MedChemExpress (MCE) Product Catalog:

27

Inhibitors & Agonists

4

Fluorescent Dye

4

Biochemical Assay Reagents

1

Peptides

2

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-103311
    Ruthenium red
    Maximum Cited Publications
    10 Publications Verification

    Ammoniated Ruthenium oxychloride

    		 Calcium Channel Cardiovascular Disease
    Ruthenium red (Ammoniated ruthenium oxychloride) is a polycationic dye widely used for electron microscopy (EM) of cells, tissues and vegetative bacteria. Ruthenium red strongly reacts with phospholipids and fatty acids and binds to acidic mucopolysaccharides. Ruthenium red is a L-type calcium current (ICa) blocker .
    Ruthenium red
  • HY-W020958
    Ru(acac)3

    Tris(acetylacetonato)Ruthenium (III)

    		 Biochemical Assay Reagents Others
    Ru(acac)3 (Tris(acetylacetonato)ruthenium (III)) is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
    Ru(acac)3
  • HY-W140535
    Tetrasodium,4-(1,10-phenanthrolin-4-yl)benzenesulfonate,ruthenium((II))

    		Fluorescent Dye Others
    Tetrasodium,4-(1,10-phenanthrolin-4-yl)benzenesulfonate,ruthenium((II)) is a luminescent indicator dye .
    Tetrasodium,4-(1,10-phenanthrolin-4-yl)benzenesulfonate,ruthenium((II))
  • HY-W074143
    Tris(4,7-diphenyl-1,10-phenanthroline)ruthenium(II) dichloride
    3 Publications Verification

    		 Fluorescent Dye Others
    Tris(4,7-diphenyl-1,10-phenanthroline)ruthenium(II) dichloride ([Ru(dpp)3] 2+) is an electrochemiluminescent (ECL) probe that can be used to modify the electrode surface to detect sulfate (S2O8 2-) and oxalate. Tris(4,7-diphenyl-1,10-phenanthroline)ruthenium(II) dichloride can generate excited state species based on electrochemical reactions and release photons through irreversible redox reactions. When used as a cathode to detect persulfate, it can avoid the interference of hydrogen evolution. At the same time, the anode shows a wide linear range for oxalate. Tris(4,7-diphenyl-1,10-phenanthroline)ruthenium(II) dichloride can be used to construct a regenerable ECL sensor .
    Tris(4,7-diphenyl-1,10-phenanthroline)ruthenium(II) dichloride
  • HY-34544
    2-Hexylthiophene

    		Others Others
    2-Hexylthiophene is an extremely weak basic heteroaromatic compound. 2-Hexylthiophene can be used to modify and improve the molar absorption coefficient of ruthenium sensitizer
    2-Hexylthiophene
  • HY-W034154
    Dihydridotetrakis(triphenylphosphine)ruthenium(II)

    Tetrakis(triphenylphosphine)Ruthenium dihydride

    		 Drug Intermediate Endogenous Metabolite
    Dihydridotetrakis(triphenylphosphine)ruthenium(II) (Tetrakis(triphenylphosphine)ruthenium dihydride) is a catalyst with good catalytic activity. Dihydridotetrakis(triphenylphosphine)ruthenium(II) can be used in organic synthesis reactions, especially in hydrogenation and dehydrogenation reactions. Dihydridotetrakis(triphenylphosphine)ruthenium(II) has received extensive attention in the study of metal catalysts, and its high efficiency makes it an ideal research object.
    Dihydridotetrakis(triphenylphosphine)ruthenium(II)
  • HY-D1708
    RuBP-4S

    		Fluorescent Dye Others
    RuBP-4S is a luminescent ruthenium complex.
    RuBP-4S
  • HY-W033559
    Carbonylhydrido(tetrahydroborato)[bis(2-diphenylphosphinoethyl) aMino]ruthenium(II)

    		Biochemical Assay Reagents
    Carbonylhydrido(tetrahydroborato)[bis(2-diphenylphosphinoethyl) aMino]ruthenium(II) is a biochemical reagent .
    Carbonylhydrido(tetrahydroborato)[bis(2-diphenylphosphinoethyl) aMino]ruthenium(II)
  • HY-150966
    Antiproliferative agent-10

    		Mitochondrial Metabolism Cancer
    Antiproliferative agent-10 (compound 8) is an anti-tumour ruthenium(II)-tris-pyrazolylmethane complex that inhibits the growth of cancer cells by inhibiting mitochondrial calcium uptake .
    Antiproliferative agent-10
  • HY-150969
    Antiproliferative agent-12

    		Mitochondrial Metabolism Cancer
    Antiproliferative agent-10 (compound 1) is an anti-tumour ruthenium(II)-tris-pyrazolylmethane complex that inhibits the growth of cancer cells by inhibiting mitochondrial calcium uptake .
    Antiproliferative agent-12
  • HY-131885
    RuBi-Glutamate hexafluorophosphate sodium

    		GABA Receptor Neurological Disease
    RuBi-Glutamate hexafluorophosphate sodium is a novel cage glutamate compound based on ruthenium photochemistry. RuBi-Glutamate hexafluorophosphate sodium can be excited at visible wavelengths and release glutamate after single or two-photon excitation. It has high quantum efficiency and can be used at low concentrations, partially avoiding the blocking of GABA energy transmission by other cage compounds. Two-photon release of RuBi-Glutamate hexafluorophosphate sodium has high spatial resolution and produces a physiodynamic excitatory response in a single dendritic spine .
    RuBi-Glutamate hexafluorophosphate sodium
  • HY-147039
    BOLD-100 free base

    NKP-1339 free base; IT-139 free base; KP-1339 free base

    		 HSP Autophagy Cancer
    BOLD-100 (NKP-1339; IT-139) free base is a ruthenium-based anticancer agent. BOLD-100 free base also is an inhibitor of stress-induced GRP78 upregulation, disrupting endoplasmic reticulum (ER) homeostasis and inducing ER stress and unfolded protein response (UPR). BOLD-100 free base interferes with the complex interplay between ER-stress response, lysosome dynamics, and autophagy execution .
    BOLD-100 free base
  • HY-16350
    BOLD-100

    NKP-1339; IT-139; KP-1339

    		 DNA/RNA Synthesis Apoptosis Cancer
    BOLD-100 (NKP-1339; IT-139) is the first-in-class ruthenium-based anticancer agent in development against solid cancer with limited side effects. BOLD-100 induces G2/M cell cycle arrest, blockage of DNA synthesis, and induction of apoptosis via the mitochondrial pathway. BOLD-100 has a high tumor targeting potential, strongly binds to serum proteins such as albumin and transferrin and activates in the reductive tumor milieu .
    BOLD-100
  • HY-19376
    NAMI-A

    		FAK Cancer
    NAMI-A is a ruthenium-based drug characterised by the selective activity against tumour metastases, inhibits the adhesion and migration.
    NAMI-A
  • HY-Y1312
    2-Phenylimidazole

    PhI; 2PZ

    		 Biochemical Assay Reagents Others
    2-Phenylimidazole (PhI) is a corrosion inhibitor for brass and can be used to prepare complexes with ruthenium (III) .
    2-Phenylimidazole
  • HY-59137
    1-Methylimidazole

    		Drug Intermediate Cancer
    1-Methylimidazole can be used as a ligand for ruthenium (II) complexes in the study of non-small cell lung cancer .
    1-Methylimidazole
  • HY-W033466
    Dichloro(benzene)ruthenium(II) dimer

    BenzeneRuthenium(II) chloride dimer

    		 Biochemical Assay Reagents Others
    Benzeneruthenium(II) Chloride Dimer is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    Dichloro(benzene)ruthenium(II) dimer
  • HY-162569
    Ru-TRZ2

    		Apoptosis Necroptosis Cancer
    Ru-TRZ2 is a potent ruthenium-based chemotherapeutic agent. Ru-TRZ2 induces apoptosis and necroptosis. Ru-TRZ2 shows antitumor activity .
    Ru-TRZ2
  • HY-103527
    RuBi-GABA

    		GABA Receptor Neurological Disease
    RuBi-GABA is a new ruthenium-based caged GABA compound. RuBi-GABA photocleaves and releases GABA after being excited with visible wavelengths. RuBi-GABA produces gaba receptor-mediated currents .
    RuBi-GABA
  • HY-157051
    [Ru(DIP)2TAP]Cl2

    		Photosensitizer Cancer
    [Ru(DIP)2TAP]Cl2, Ruthenium(II) polypyridyl compound, is a photosensitizer. [Ru(DIP)2TAP]Cl2 can be used for the research of photodynamic therapy (PDT) .
    [Ru(DIP)2TAP]Cl2
  • HY-34544R
    2-Hexylthiophene (Standard)

    		Others Others
    Daucosterol (Standard) is the analytical standard of Daucosterol. This product is intended for research and analytical applications. Daucosterol is an orally active natural sterol compound, which has anti-inflammatory, anticancer and immunomodulatory activities. Daucosterol inhibits cancer cell proliferation by inducing autophagy through ROS-dependent manner. Daucosterol also inhibits colon cancer growth by inducing apoptosis, inhibiting cell migration and invasion and targeting caspase signalling pathway .
    2-Hexylthiophene (Standard)
  • HY-150968
    Antiproliferative agent-11

    		Apoptosis Cancer
    Antiproliferative agent-11 (compound 7) is an antiproliferative and selective Ruthenium(II)-Tris-pyrazolylmethane complex. Antiproliferative agent-11 shows antiproliferative activity towards MCF-7, HeLa, 518A2, HCT116 and RD with IC50s of 6, 10, 6.8, 6.7 and 6 μM, respectively. Antiproliferative agent-11 can be used for the research of cancer .
    Antiproliferative agent-11
  • HY-W591060
    Bis(bipyridine)-(5-aminophenanthroline)

    		Biochemical Assay Reagents Endogenous Metabolite
    Bis(bipyridine)-(5-aminophenanthroline) is an organic catalyst with photocatalytic activity. The use of Bis(bipyridine)-(5-aminophenanthroline) in hematology involves its use as a stain for tissue diagnosis. Bis(bipyridine)-(5-aminophenanthroline) can be used as a transition metal catalyst in catalytic reactions. Bis(bipyridine)-(5-aminophenanthroline) has also been used in the study of ruthenium catalysts.
    Bis(bipyridine)-(5-aminophenanthroline)
  • HY-W127790
    Bathophenanthrolinedisulfonic acid disodium

    		Biochemical Assay Reagents Others
    Bathophenanthrolinedisulfonic acid disodium salt (BPS) is a colorimetric reagent for iron detection, with a wavelength of 535 nm for iron complex. It can be used for iron determination in aqueous solution systems without the need for extraction solvents. BPS can serve as a precursor to prepare Europium(III) tris(dibenzoylmethanate) bis(bathophenanthrolinedisulfonate) complex and ruthenium(II) tris(bathophenanthrolinedisulfonate), or participate in the catalytic oxidation of 2-hexanol by forming water-soluble complexes with palladium .
    Bathophenanthrolinedisulfonic acid disodium
  • HY-W127716
    Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2
    1 Publications Verification

    		 Fluorescent Dye Cancer
    Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2 is a potent ruthenium-based dye. Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2 can bu used as an effective quencher of quantum dots (QDs) fluorescence and the capture probe of virus antigen EV71. Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2 can be used sensitive electrogenerated chemiluminescence (ECL) labels for detection of matrix metalloproteinases (MMPs) .
    Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2
  • HY-W127832
    Ru(dpp)3(PF6)2

    		Fluorescent Dye Others
    Ru(dpp)3(PF6)2 is a complex containing metallic ruthenium (Ru) and is a chemiluminescent oxygen probe. [Ru(dpp)3] 2+ is a luminescent substance that can undergo metal-to-ligand charge transfer (MLCT), and fluorescence will appear during the transfer of Ru to the ligand. At the same time, the fluorescence of Ru(dpp)3(PF6)2 is effectively quenched by molecular oxygen, so it is widely used in biosensors, environmental monitoring, and materials science. The property of Ru(dpp)3(PF6)2, which oxidizes Ru 2+ to Ru 3+, has also been used to design and construct solid-state light-emitting electrochemical cells .
    Ru(dpp)3(PF6)2
  • HY-P10667
    Ac-MRGDH-NH2

    		Integrin Cancer
    Ac-MRGDH-NH2 is a pentapeptide containing the RGD sequence. Ac-MRGDH-NH2 can be used to synthesize the diastereoisomeric prodrugs Λ- and Δ-[Ru(Ph2phen)2(κS,κN-(Ac-MRGDH-NH2))]Cl2. In these prodrugs, Ac-MRGDH-NH2 serves as a photolabile protecting group for the cytotoxic bis-aqua ruthenium warhead [Ru(Ph2phen)2(OH2)2]2+, and Ac-MRGDH-NH2 possesses integrin targeting ability and photosubstitution properties. Therefore, Ac-MRGDH-NH2 can be utilized in research on tumor-targeted photodynamic activation chemotherapy (PACT) .
    Ac-MRGDH-NH2

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