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Saponin

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By Research Areas:	Cancer (67) Cardiovascular Disease (12) Infection (22) Inflammation/Immunology (75) Metabolic Disease (36) Neurological Disease (18)
Oligonucleotides:	Adjuvant (12)

276

Inhibitors & Agonists

269

Natural
Products

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-100597

Saponins 3 Publications Verification Saponin	Fungal Bacterial	Inflammation/Immunology
Saponins (Saponin) is a class of chemical compound of glycosides found in particular abundance in various plant species. In plants, Saponins may serve as anti-feedants, and to protect the plant against microbes and fungi .

HY-N5055

Saponin C, from Liriope muscari	Others	Others
Saponin C, from Liriope muscari is isolated from Liriope muscari.

HY-N3584

*Paris saponin* VII** 2 Publications Verification Chonglou Saponin VII	Akt p38 MAPK P-glycoprotein Bcl-2 Family Caspase PARP Autophagy Apoptosis	Cancer
Paris saponin VII (Chonglou Saponin VII) is a steroidal saponin isolated from the roots and rhizomes of Trillium tschonoskii. Paris saponin VII-induced apoptosis in K562/ADR cells is associated with Akt/MAPK and the inhibition of P-gp. Paris saponin VII attenuates mitochondrial membrane potential, increases the expression of apoptosis-related proteins, such as Bax and cytochrome c, and decreases the protein expression levels of Bcl-2, caspase-9, caspase-3, PARP-1, and p-Akt. Paris saponin VII induces a robust autophagy in K562/ADR cells and provides a biochemical basis in the treatment of leukemia .

HY-107233

Saponin CP4 Prosapogenin CP4	Others	Others
Saponin CP4 is an oleanolic acid derivative which lacks a 23-OH. Saponin CP4 shows no growth inhibition .

HY-107235

Saponin CP6 Clematoside S; Prosapogenin CP6	Others	Others
Saponin CP6 is a triterpenoid compound from the roots of Clematis grata .

HY-N7974

*Kizuta saponin* K11**	Others	Others
Kizuta saponin K11 is a saponin found in the leaves of Kalopanax pictum var. maximowiczii, a Korean medicinal plant .

HY-N11034

*24-Hydroxy-licorice-saponin* A3**	Others	Others
24-Hydroxy-licorice-saponin A3 is an oleanane-type triterpene saponin (OTS). 24-Hydroxy-licorice-saponin A3 can be isolated from G. uralensis. .

HY-N9332

*Kalopanax saponin* G**	Others	Others
Kalopanax saponin G is an ester glycoside of oleanolic acid possessing no sugar moiety at the C-3 hydroxyl group. Kalopanax saponin G is isolated from the bark of Kalopanax pictus .

HY-N4229

*Clematomandshurica saponin* C**	Others	Others
Clematomandshurica saponin C is found in Clematis manshurica .

HY-N4230

*Clematomandshurica saponin* B**	COX	Inflammation/Immunology
Clematomandshurica saponins B shows significant inhibitory activity on cyclooxygenase-2 (IC₅₀=2.58 mM) .

HY-N6068

*Pulsatilla saponin* H** Hederacolchiside F	Others	Others
Pulsatilla saponin H is a natural compound isolated from the Roots of Pulsatilla koreana .

HY-N6911

*Licorice-saponin* H2** (18β,20α)-Glycyrrhizic acid	Others	Metabolic Disease
Licorice-saponin H2 ((18β,20α)-Glycyrrhizic acid) is a saponin from Glycyrrhiza uralensis Fischer .

HY-N0834

*Pulsatilla saponin* D** SB365; Hederacolchiside A	Apoptosis	Cancer
Pulsatilla saponin D (SB365), isolated from the root of Pulsatilla chinensis, is an anti-tumor agent .

HY-N10074

Polygalacin D2	Others	Others
Polygalacin D2 is a saponin isolated from Platycodon grandiflorum .

HY-N11448

Bupleuroside XIII	Others	Metabolic Disease
Bupleuroside XIII is a natural hepatoprotective saponin .

HY-N12152

Molluscicidal agent-1	Others	Others
Molluscicidal agent-1 (Compound 3) is a saponin that can be isolated from S.vesicaria .

HY-N7952

Achyranthoside D	Others	Others
Achyranthoside D is a triterpene saponin from Achyranthes root .

HY-N2386

Polyphyllin E	Others	Others
Polyphyllin E is a steroidal saponin that can be isolated from Paris polyphylla .

HY-N12355

Disporoside C	Others	Others
Disporoside C is a steroidal saponin can be isolated from Disporopsis pernyi .

HY-N4272

Protodeltonin	Others	Cancer
Protodeltonin is a steroidal saponin from Dioscorea zingiberensis Wright, with anti-proliferation activity .

HY-N2516

Ginsenoside Rd2	Others	Inflammation/Immunology
Ginsenoside Rd2 is a saponin found in Panax japonicus with anti-inflammatory actions .

HY-N11923

Lysimachigenoside C	Others	Others
Lysimachigenoside C is a triterpene saponin isolated from Lysimachia foenum-graecum Hance .

HY-N11810

Polyfuroside	Others	Others
Polyfuroside is a triterpenoid saponin, which can be isolated from the defatted rhizome of jade bamboo .

HY-N12065

Parisyunnanoside H	Others	Others
Parisyunnanoside H is a steroidal saponin isolated from Paris polyphylla Smith var. yunnanensis* .*

HY-N6911B

*Licorice-saponin* H2 ammonium** (18β,20α)-Glycyrrhizic acid ammonium	Others	Others
Licorice-saponin H2 ammonium (compound 7) is a type of oleanolic acid triterpene glycoside that can be isolated from the roots of licorice .

HY-16941

Damulin A	Others	Cancer
Damulin A is a saponin found in G. pentaphyllum with anti-cancer activities .

HY-N8235

Virgaureagenin F	Others	Others
Virgaureagenin F is a saponin that can be extracted from the rhizoma bolbostemmae .

HY-N2046

Jujuboside D Jujuboside A1	Others	Others
Jujuboside D (Jujuboside A1) is a dammarane-type saponin that can be isolated from the seeds of Ziziphus jujube .

HY-N8662

Primulic acid II	Others	Inflammation/Immunology
Primulic acid II is a saponin isolated from root extract of Primula sp .

HY-N12148

Macrostemonoside I	Others	Others
Macrostemonoside I is a furostanol saponin that can be isolated from Allium macrostemon .

HY-N4262

Ginsenoside Rh7	Others	Others
Ginsenoside Rh7 is a minor saponin isolated from the leaves of Panax ginseng .

HY-N4217

Saikosaponin I	Others	Others
Saikosaponin I is a triterpene saponin extracted from Bupleurum falcatum L. Saikosaponin can be used to treat fever, inflammation, liver disease, and nephritis .

HY-N12533

Quinquenoside R1	Others	Others
Quinquenoside R1 (Compound 12) is a saponin compound that can be isolated from wild ginseng .

HY-N12292

Acanthopanaxoside A	Others	Metabolic Disease
Acanthopanaxoside A, a triterpenoid saponin, has pancreatic lipase inhibitory action .

HY-N8215

Achyranthoside C	Others	Metabolic Disease
Achyranthoside C is a saponin from Achyranthes bidentata. The derivative of Achyranthoside C has inhibitory activity on osteoclast formation .

HY-W019830

Polyphyllin F	Others	Others
Polyphyllin F is a diosgenyl saponin that can be found in Paris polyphylla .

HY-N8410

Momordicoside P	Others	Others
Momordicoside P is a cucurbitane-type triterpenoid saponin. Momordicoside P can be isolated from the fresh fruits of Momordica charantia .

HY-N8901

20-Gluco-ginsenoside-Rf	Biochemical Assay Reagents	Others
20-Gluco-ginsenoside-Rf (compound 4) is a bisdesmosidic saponin that can be obtained from the roots of Panax ginseng .

HY-N12587

Platycoside F	Others	Inflammation/Immunology
Platycoside F is a triterpenoid saponin compound that can be isolated from the roots of Platycodon grandiflorum .

HY-125686

Beesioside Q	Others	Others
Beesioside Q is a oleanolic acid triterpene saponin isolated from the rhizome of Beesia calthaefolia (Maxim.) Ulbr .

HY-107242

Raddeanoside R8	Others	Others
Raddeanoside R8 is a saponin that can be isolated from fresh rhizoma of Anemone raddeana Regel .

HY-N8112

Polygalasaponin LII	Others	Others
Polygalasaponin LII is a triterpenoid saponin that ca n be isolated from the roots of Polygala japonica Houtt .

HY-N12298

Ciwujianoside C1	Others	Others
Ciwujianoside C1 is a saponin, that can be isolated from the leaves of Acanthopanax senticosus. Ciwujianoside C1 inhibits pancreatic lipase activity in vitro .

HY-N8922

Platycodin A	Others	Others
Platycodin A is monoacetylated saponin compound isolated fromhe roots of Platycodon grandiflorum A. DC. .

HY-107236

Huzhangoside D	Others	Others
Huzhangoside D is a saponin compound isolated from the roots and rhizomes of Clematis graveolens .

HY-N4064

Hederagonic acid	Others	Others
Hederagenic acid (compound 2) is a kind of triterpenoid saponin. Hederagenic acid can be isolated from the roots of Kalopanax septemlobus (Thunb.) Koidz .

HY-N4264

Vinaginsenoside R3	Others	Inflammation/Immunology
Vinaginsenoside R3 is a saponin composition of roots of Panax ginseng. Ginsengs have been not only used as therapeutic agents with tonic, anti-fatigue, and anti-gastric ulcer effect but also marketed as dietary supplements and raw materials of health food .

HY-N11073

Clematiganoside A	Others	Others
Clematiganoside A is a triterpenoid saponin that can be isolatred from Clematis ganpiniana .

HY-N1439

Methyl gypsogenin-3-O-glucuronide Gypsogenin-3-O-(6-O-methyl)-glucoside	Others	Inflammation/Immunology
Methyl gypsogenin-3-O-glucuronide (Gypsogenin-3-O-(6-O-methyl)-glucoside) is a ubiquitous saponin precursor in plants of the genus Gypsophila .

HY-N11983

(25R)-Ruscogenin-3-yl α-L-rhamnopyranosyl-(1→2)-[β-D-xylopyranosyl-(1→4)]-β-D-glucopyranoside	Others	Others
(25R)-Ruscogenin-3-yl α-L-rhamnopyranosyl-(1→2)-[β-D-xylopyranosyl-(1→4)]-β-D-glucopyranoside (compound 1) is a steroidal saponin , can be isolated from the roots of Ophiopogon japonicus .

Cat. No.	Product Name		Classification

HY-159751

HS101		Adjuvant
HS101 is a vaccine adjuvant and a key component in vaccines. Adjuvants can be divided into immunostimulants and delivery systems. Adjuvants can not only enhance the intensity and durability of immune responses, but also affect the type of immune responses. On the one hand, immunostimulants promote the production of antigen signals and co-stimulatory signals by targeting Toll-like receptors (TLRs) and other pattern recognition receptors (PRRs), leading to the maturation and activation of antigen presenting cells (APCs), thereby enhancing adaptive immune responses; on the other hand, delivery systems are carrier materials that promote antigen delivery by prolonging the bioavailability of loaded antigens and targeting antigens to lymph nodes or APCs. Several common adjuvants include: saponins, TLRs agonists, polysaccharides, nanoparticles, cytokines, and mucosal adjuvants .

HY-159752

HS103		Adjuvant
HS103 is a vaccine adjuvant and a key component in vaccines. Adjuvants can be divided into immunostimulants and delivery systems. Adjuvants can not only enhance the intensity and durability of immune responses, but also affect the type of immune responses. On the one hand, immunostimulants promote the production of antigen signals and co-stimulatory signals by targeting Toll-like receptors (TLRs) and other pattern recognition receptors (PRRs), leading to the maturation and activation of antigen presenting cells (APCs), thereby enhancing adaptive immune responses; on the other hand, delivery systems are carrier materials that promote antigen delivery by prolonging the bioavailability of loaded antigens and targeting antigens to lymph nodes or APCs. Several common adjuvants include: saponins, TLRs agonists, polysaccharides, nanoparticles, cytokines, and mucosal adjuvants .

HY-159753

HS105		Adjuvant
HS105 is a vaccine adjuvant and a key component in vaccines. Adjuvants can be divided into immunostimulants and delivery systems. Adjuvants can not only enhance the intensity and durability of immune responses, but also affect the type of immune responses. On the one hand, immunostimulants promote the production of antigen signals and co-stimulatory signals by targeting Toll-like receptors (TLRs) and other pattern recognition receptors (PRRs), leading to the maturation and activation of antigen presenting cells (APCs), thereby enhancing adaptive immune responses; on the other hand, delivery systems are carrier materials that promote antigen delivery by prolonging the bioavailability of loaded antigens and targeting antigens to lymph nodes or APCs. Several common adjuvants include: saponins, TLRs agonists, polysaccharides, nanoparticles, cytokines, and mucosal adjuvants .

HY-159754

HS201		Adjuvant
HS201 is a vaccine adjuvant and a key component in vaccines. Adjuvants can be divided into immunostimulants and delivery systems. Adjuvants can not only enhance the intensity and durability of immune responses, but also affect the type of immune responses. On the one hand, immunostimulants promote the production of antigen signals and co-stimulatory signals by targeting Toll-like receptors (TLRs) and other pattern recognition receptors (PRRs), leading to the maturation and activation of antigen presenting cells (APCs), thereby enhancing adaptive immune responses; on the other hand, delivery systems are carrier materials that promote antigen delivery by prolonging the bioavailability of loaded antigens and targeting antigens to lymph nodes or APCs. Several common adjuvants include: saponins, TLRs agonists, polysaccharides, nanoparticles, cytokines, and mucosal adjuvants .

HY-159746

HS801		Adjuvant
HS801 is a vaccine adjuvant and a key component in vaccines. Adjuvants can be divided into immunostimulants and delivery systems. Adjuvants can not only enhance the intensity and durability of immune responses, but also affect the type of immune responses. On the one hand, immunostimulants promote the production of antigen signals and co-stimulatory signals by targeting Toll-like receptors (TLRs) and other pattern recognition receptors (PRRs), leading to the maturation and activation of antigen presenting cells (APCs), thereby enhancing adaptive immune responses; on the other hand, delivery systems are carrier materials that promote antigen delivery by prolonging the bioavailability of loaded antigens and targeting antigens to lymph nodes or APCs. Several common adjuvants include: saponins, TLRs agonists, polysaccharides, nanoparticles, cytokines, and mucosal adjuvants .

HY-159743

M101		Adjuvant
M101 is a vaccine adjuvant and a key component in vaccines. Adjuvants can be divided into immunostimulants and delivery systems. Adjuvants can not only enhance the intensity and durability of immune responses, but also affect the type of immune responses. On the one hand, immunostimulants promote the production of antigen signals and co-stimulatory signals by targeting Toll-like receptors (TLRs) and other pattern recognition receptors (PRRs), leading to the maturation and activation of antigen presenting cells (APCs), thereby enhancing adaptive immune responses; on the other hand, delivery systems are carrier materials that promote antigen delivery by prolonging the bioavailability of loaded antigens and targeting antigens to lymph nodes or APCs. Several common adjuvants include: saponins, TLRs agonists, polysaccharides, nanoparticles, cytokines, and mucosal adjuvants .

HY-159744

M103		Adjuvant
M103 is a vaccine adjuvant and a key component in vaccines. Adjuvants can be divided into immunostimulants and delivery systems. Adjuvants can not only enhance the intensity and durability of immune responses, but also affect the type of immune responses. On the one hand, immunostimulants promote the production of antigen signals and co-stimulatory signals by targeting Toll-like receptors (TLRs) and other pattern recognition receptors (PRRs), leading to the maturation and activation of antigen presenting cells (APCs), thereby enhancing adaptive immune responses; on the other hand, delivery systems are carrier materials that promote antigen delivery by prolonging the bioavailability of loaded antigens and targeting antigens to lymph nodes or APCs. Several common adjuvants include: saponins, TLRs agonists, polysaccharides, nanoparticles, cytokines, and mucosal adjuvants .

HY-159745

M107		Adjuvant
M107 is a vaccine adjuvant and a key component in vaccines. Adjuvants can be divided into immunostimulants and delivery systems. Adjuvants can not only enhance the intensity and durability of immune responses, but also affect the type of immune responses. On the one hand, immunostimulants promote the production of antigen signals and co-stimulatory signals by targeting Toll-like receptors (TLRs) and other pattern recognition receptors (PRRs), leading to the maturation and activation of antigen presenting cells (APCs), thereby enhancing adaptive immune responses; on the other hand, delivery systems are carrier materials that promote antigen delivery by prolonging the bioavailability of loaded antigens and targeting antigens to lymph nodes or APCs. Several common adjuvants include: saponins, TLRs agonists, polysaccharides, nanoparticles, cytokines, and mucosal adjuvants .

HY-159747

M401		Adjuvant
M401 is a vaccine adjuvant and a key component in vaccines. Adjuvants can be divided into immunostimulants and delivery systems. Adjuvants can not only enhance the intensity and durability of immune responses, but also affect the type of immune responses. On the one hand, immunostimulants promote the production of antigen signals and co-stimulatory signals by targeting Toll-like receptors (TLRs) and other pattern recognition receptors (PRRs), leading to the maturation and activation of antigen presenting cells (APCs), thereby enhancing adaptive immune responses; on the other hand, delivery systems are carrier materials that promote antigen delivery by prolonging the bioavailability of loaded antigens and targeting antigens to lymph nodes or APCs. Several common adjuvants include: saponins, TLRs agonists, polysaccharides, nanoparticles, cytokines, and mucosal adjuvants .

HY-159748

M402		Adjuvant
M402 is a vaccine adjuvant and a key component in vaccines. Adjuvants can be divided into immunostimulants and delivery systems. Adjuvants can not only enhance the intensity and durability of immune responses, but also affect the type of immune responses. On the one hand, immunostimulants promote the production of antigen signals and co-stimulatory signals by targeting Toll-like receptors (TLRs) and other pattern recognition receptors (PRRs), leading to the maturation and activation of antigen presenting cells (APCs), thereby enhancing adaptive immune responses; on the other hand, delivery systems are carrier materials that promote antigen delivery by prolonging the bioavailability of loaded antigens and targeting antigens to lymph nodes or APCs. Several common adjuvants include: saponins, TLRs agonists, polysaccharides, nanoparticles, cytokines, and mucosal adjuvants .

HY-159749

M902		Adjuvant
M902 is a vaccine adjuvant and a key component in vaccines. Adjuvants can be divided into immunostimulants and delivery systems. Adjuvants can not only enhance the intensity and durability of immune responses, but also affect the type of immune responses. On the one hand, immunostimulants promote the production of antigen signals and co-stimulatory signals by targeting Toll-like receptors (TLRs) and other pattern recognition receptors (PRRs), leading to the maturation and activation of antigen presenting cells (APCs), thereby enhancing adaptive immune responses; on the other hand, delivery systems are carrier materials that promote antigen delivery by prolonging the bioavailability of loaded antigens and targeting antigens to lymph nodes or APCs. Several common adjuvants include: saponins, TLRs agonists, polysaccharides, nanoparticles, cytokines, and mucosal adjuvants .

HY-159750

M903		Adjuvant
M903 is a vaccine adjuvant and a key component in vaccines. Adjuvants can be divided into immunostimulants and delivery systems. Adjuvants can not only enhance the intensity and durability of immune responses, but also affect the type of immune responses. On the one hand, immunostimulants promote the production of antigen signals and co-stimulatory signals by targeting Toll-like receptors (TLRs) and other pattern recognition receptors (PRRs), leading to the maturation and activation of antigen presenting cells (APCs), thereby enhancing adaptive immune responses; on the other hand, delivery systems are carrier materials that promote antigen delivery by prolonging the bioavailability of loaded antigens and targeting antigens to lymph nodes or APCs. Several common adjuvants include: saponins, TLRs agonists, polysaccharides, nanoparticles, cytokines, and mucosal adjuvants .

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Saponin

Inhibitors & Agonists

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