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Results for "

Sophora

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Akt (3) Apoptosis (15) Autophagy (6) Bacterial (3) Beta-secretase (1) Carboxylesterase (1) Cytochrome P450 (2) Estrogen Receptor/ERR (1) Ferroptosis (2) Filovirus (1) Fungal (2) Glucosidase (1) HIV (1) HSV (1) Indoleamine 2,3-Dioxygenase (IDO) (1) Influenza Virus (3) Mitophagy (2) Opioid Receptor (2) Phosphodiesterase (PDE) (1) PI3K (3) PINK1/Parkin (2) RANKL/RANK (1) SGLT (1) TGF-beta/Smad (2) TNF Receptor (2) Tyrosinase (4)
By Research Areas:	Cancer (26) Cardiovascular Disease (3) Infection (12) Inflammation/Immunology (18) Metabolic Disease (4) Neurological Disease (2)

By Targets:

Akt (3)

Apoptosis (15)

Autophagy (6)

Bacterial (3)

Beta-secretase (1)

Carboxylesterase (1)

Cytochrome P450 (2)

Estrogen Receptor/ERR (1)

Ferroptosis (2)

Filovirus (1)

Fungal (2)

Glucosidase (1)

HIV (1)

HSV (1)

Indoleamine 2,3-Dioxygenase (IDO) (1)

Influenza Virus (3)

Mitophagy (2)

Opioid Receptor (2)

Phosphodiesterase (PDE) (1)

PI3K (3)

PINK1/Parkin (2)

RANKL/RANK (1)

SGLT (1)

TGF-beta/Smad (2)

TNF Receptor (2)

Tyrosinase (4)

By Research Areas:

Cancer (26)

Cardiovascular Disease (3)

Infection (12)

Inflammation/Immunology (18)

Metabolic Disease (4)

Neurological Disease (2)

Inhibitors & Agonists

Natural
Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N5096

Sophorabioside	Others	Others
Sophorabioside is a flavonoid-glycoside isolated from Sophora japonica .

HY-N2529

Sophoranone (-)-Sophoranone; Sophoranon	Others	Neurological Disease
Sophoranone is a flavonoid compound that can be isolated from the root of Sophora subprostrata .

HY-N1231

Sophoraflavanone G 1 Publications Verification Kushenol F	Apoptosis	Cancer
Sophoraflavanone G (Kushenol F) is iaolated from Sophora flavescens and shows anti-tumor and anti-inflammatory properties.? Sophoraflavanone G (Kushenol F) induces MDA-MB-231 and HL-60 cells apoptosis through suppression of MAPK-related pathways .

HY-N8998

Sophoraflavanone I	Others	Others
Sophoraflavanone I the seeds of Sophora moorcroftiana BENTH. ex. BAKER (Leguminosae) .

HY-N8964

Sophoraflavanone H	Others	Others
Sophoraflavanone H is a Flavonoids product that can be isolated from the roots of Sophora moorcroftiana. .

HY-N8827

Sophoracarpan A	Others	Others
Sophoracarpan A is a Flavonoids product that can be isolated from the aerial parts of Sophora tomentosa L. .

HY-N1231R

Sophoraflavanone G (Standard)	Apoptosis	Cancer
Sophoraflavanone G (Standard) is the analytical standard of Sophoraflavanone G. This product is intended for research and analytical applications. Sophoraflavanone G (Kushenol F) is iaolated from Sophora flavescens and shows anti-tumor and anti-inflammatory properties. Sophoraflavanone G (Kushenol F) induces MDA-MB-231 and HL-60 cells apoptosis through suppression of MAPK-related pathways .

HY-N13187

7,3'-Dihydroxy flavonone-4'-O-β-D-glucopyranoside	Others	Others
7,3'-Dihydroxy flavonone-4'-O-β-D-glucopyranoside is derivated from the seeds of Sophora alopecuroides L. .

HY-N7806

7,3'-Di-O-Methylorobol	Others	Others
7,3'-Di-O-Methylorobol is a flavone that can be isolated from Sophora japonica .

HY-N1344

Robtin	Others	Cardiovascular Disease
Robtin (Compound 4) is a natural product isolated and purified from Sophora yunnanensis. Robtin has cardiotonic activity .

HY-N8095

Kushenol N	Others	Cardiovascular Disease
Kushenol N is a prenylated flavonoid that can be isolated from the root of Sophora flavescens. Kushenol N has anti-allergic and vasorelaxation activities .

HY-N8097

Kushenol W	Bacterial	Infection
Kushenol W is a prenylated flavonoid that can be isolated from the root of Sophora flavescens. Kushenol W has antimicrobial effect, with a MIC of 10 μg/mL for Staphylococcus aureus .

HY-N5009

Thermopsine	Bacterial	Infection
Thermopsine is a quinolizidine alkaloid isolated from the fruits and pods and stem bark of Sophora velutina subsp. Thermopsine has antibacterial activity .

HY-121381

Kuraridine	Phosphodiesterase (PDE)	Others
Kuraridine is a prenylated flavonol extract from the roots of Sophora flavescens. Kuraridine has an inhibitory effect on cGMP specific phosphodiesterase type 5 (PDE5) (IC₅₀=0.64 μM) .

HY-N2779

8-Lavandulylkaempferol	Others	Cancer
8-Lavandulylkaempferol is a flavonoid that can be isolated from Sophora flaWescens. 8-Lavandulylkaempferol exhibits cytotoxic activity against the KB epidermoid carcinoma cell line with an IC₅₀ of 15.1 μg/mL .

HY-N2286

Kushenol I 1 Publications Verification	Others	Inflammation/Immunology
Kushenol I is a natural compound isolated from the roots of Sophora flavescens .

HY-N1287

Sepinol	Others	Others
Sepinol is a Flavonoids product that can be isolated from the herbs of Sophora viciifolia .

HY-N1574

Puerol A	Others	Others
Puerol A is a Phenols product that can be isolated from the stem barks of Sophora japonica. .

HY-N10787

Methylkushenol C	Others	Others
Methylkushenol C is a phenolic substance. Methylkushenol C can be isolated from Sophora flavescens .

HY-N11671

9α-Hydroxymatrine	Others	Others
9α-Hydroxymatrine is a quinolizidine alkaloid that can be found in the leaves of Sophora macrocarpa .

HY-N9131

6-Methylgenistein	Others	Others
6-Methylgenistein is a Flavonoids product that can be isolated from the roots of Sophora dunnii. .

HY-N2847

alpha-Isowighteone	Others	Others
alpha-Isowighteone is a Flavonoids product that can be isolated from the roots of Sophora flavescens .

HY-13516

Aloperine 4 Publications Verification	Apoptosis Autophagy Filovirus HIV	Infection Inflammation/Immunology Cancer
Aloperine is an alkaloid in sophora plants such as Sophora alopecuroides L, which has shown anti-cancer, anti-inflammatory and anti-virus properties . Aloperine is widely used to treat patients with allergic contact dermatitis eczema and other skin inflammation in China . Aloperine induces apoptosis and autophagy in HL-60 cells .

HY-N0423

Sophoricoside 1 Publications Verification	Others	Inflammation/Immunology Cancer
Sophoricoside is an isoflavone glycoside isolated from Sophora japonica and has anti-inflammatory, anti-cancer and immunosuppressive effects.

HY-N8899

Daidzein-4'-glucoside	Others	Others
Daidzein-4'-glucoside is a Flavonoids product that can be isolated from the fruits of Sophora japonica L. .

HY-N9083

8α-Hydroxy-α-gurjunene	Others	Others
8α-Hydroxy-α-gurjunene is a Flavonoids product that can be isolated from the aerial parts of Sophora tomentosa L. .

HY-122933

Kurarinol	Tyrosinase Apoptosis	Cardiovascular Disease Cancer
Kurarinol is a flavanone found in the root of Sophora flavescens. Kurarinol is a competitive tyrosinase inhibitor, with IC₅₀ of 0.1 μM for mushroom tyrosinase .

HY-N6051

(-)-Maackiain	Fungal	Infection
(-)-Maackiain is a pterocarpan phytoalexin produced from Sophora flavescens. (-)-Maackiain is toxic to several genera of fungal pathogens of legume and non legume hosts .

HY-N2279

Kurarinone 2 Publications Verification	Others	Inflammation/Immunology
Kurarinone, a flavanoid derived from shrub Sophora flavescens, inhibits the process of experimental autoimmune encephalomyelitis via blocking Th1 and Th17 cell differentiation .

HY-N0050

Allomatrine (+)-Allomatrine	Others	Neurological Disease
Allomatrine ((+)-Allomatrine) is an alkaloid from the bark of Sophora japonica. Allomatrine has antinociceptive properties mediated mainly through the activation ofκ-opioid receptors .

HY-N0423R

Sophoricoside (Standard)	Others	Inflammation/Immunology Cancer
Sophoricoside (Standard) is the analytical standard of Sophoricoside. This product is intended for research and analytical applications. Sophoricoside is an isoflavone glycoside isolated from Sophora japonica and has anti-inflammatory, anti-cancer and immunosuppressive effects.

HY-N8094

Kushenol M	Cytochrome P450	Others
Kushenol M is a flavonoid from Sophora flavescens. Kushenol M is a cytochrome P450 (CYP) inhibitor, with IC₅₀ values of 1.29 μM for CYP3A4 in human liver microsomes .

HY-N0616

Trifolirhizin	TNF Receptor Tyrosinase	Inflammation/Immunology Cancer
Trifolirhizin is a pterocarpan flavonoid isolated from the roots of Sophora flavescens. Trifolirhizin possesses potent tyrosinase inhibitory activity with an IC₅₀ of 506 μM . Trifolirhizin exhibits potential anti-inflammatory and anticancer activities .

HY-N1402

Oxysophoridine Sophoridine N-oxide	Apoptosis	Inflammation/Immunology
Oxysophoridine (Sophoridine N-oxide) is a bioactive alkaloid extracted from the Sophora alopecuroides Linn. Oxysophoridine (Sophoridine N-oxide) shows anti inflammatory, anti oxidative stress and anti apoptosis effects .

HY-N3414

Kushenol L	Others	Metabolic Disease
Kushenol L is one of the main components of EtOA cextracts from Kushen, a traditional medicinal herb derived from the dried roots of Sophora flavescens Ait. Kushenol L is a flavonoid and plays an important role in anti-diabeticeffects .

HY-N5143

(2R)-3α,7,4'-Trihydroxy-5-methoxy-8-prenylflavanone	Others	Others
(2R)-3α,7,4'-Trihydroxy-5-methoxy-8-prenylflavanone is isolated from the roots of Sophora flavescens .

HY-N1373

Sophoridine 3 Publications Verification	Apoptosis	Cancer
Sophoridine is a quinolizidine alkaloid isolated from Leguminous plant Sophora flavescens. Sophoridine induces apoptosis. Sophoridine has the potential to be a novel, potent and selective antitumor agent candidate for pancreatic cancer with well-tolerated toxicity .

HY-N0746

Oxysophocarpine 4 Publications Verification	Others	Cancer
Oxysophocarpine is an alkaloid extracted from Sophora alopecuroides.?Oxysophocarpine has neuroprotective and anti-nociceptive effects on the central and peripheral nervous systems . Oxysophocarpine inhibits the?growth?and?metastasis?of ?oral?squamous?cell?carcinoma?(OSCC) .

HY-N5129

Genistein 7-O-β-D-glucopyranoside-4'-O-[α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranoside]	Others	Others
Genistein 7-O-β-D-glucopyranoside-4'-O-[α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranoside] is an isoflavone triglycoside that could be isolated from Sophora japonica .

HY-N6051R

(-)-Maackiain (Standard)	Fungal	Infection
(-)?-Maackiain (Standard) is the analytical standard of (-)?-Maackiain. This product is intended for research and analytical applications. (-)-Maackiain is a pterocarpan phytoalexin produced from Sophora flavescens. (-)-Maackiain is toxic to several genera of fungal pathogens of legume and non legume hosts .

HY-N2463

Kushenol E	Indoleamine 2,3-Dioxygenase (IDO)	Cancer
Kushenol E is a class of flavonoids isolated from Sophora flavescens and is a non-competitive indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor with an IC₅₀ of 7.7 µM and a K_i of 9.5 µM, has anti-tumor activity .

HY-108966

Kushenol C	Beta-secretase	Inflammation/Immunology
Kushenol C, isolated from the roots of Sophora flavescens, shows anti-Inflammatory and anti-oxidative stress activities. Kushenol C inhibits BACE1 (β-site APP cleaving enzyme 1) with an IC₅₀ of 5.45 µM .

HY-N3413

Kushenol X	Carboxylesterase	Metabolic Disease
Kushenol X, a flavonoid compound isolated from the roots of Sophora flavescens. Kushenol X is a potent β-glucuronidase and human carboxylesterase 2 (hCE2) inhibitor with IC₅₀s of 2.07 μM and 3.05 μM, respectively .

HY-N8228

17-Hydroxyneomatrine	Bacterial	Infection Inflammation/Immunology Cancer
17-Hydroxyneomatrine, extracted from Sophora flavescens, can well inhibit the growth of human cervical carcinoma Hela cells, has the wide-range antibacterial, anti-allergy, anti-tumor, anti-arrhythmia, swelling-subsiding diuresis, immunizing, and biological regulation functions .

HY-N0158

Oxymatrine Maximum Cited Publications 14 Publications Verification	TGF-beta/Smad Apoptosis	Infection Inflammation/Immunology Cancer
Oxymatrine, an alkaloid from Sophora flavescens Alt. with anti-inflammatory, antifibrosis, and antitumor effects, inhibits the iNOS expression and TGF-β/Smad pathway. Oxymatrine inhibits bocavirus minute virus of canines (MVC) replication, reduces viral gene expression and decreases apoptosis induced by viral infection.

HY-N0616R

Trifolirhizin (Standard)	TNF Receptor Tyrosinase	Inflammation/Immunology Cancer
Trifolirhizin (Standard) is the analytical standard of Trifolirhizin. This product is intended for research and analytical applications. Trifolirhizin is a pterocarpan flavonoid isolated from the roots of Sophora flavescens. Trifolirhizin possesses potent tyrosinase inhibitory activity with an IC₅₀ of 506 μM . Trifolirhizin exhibits potential anti-inflammatory and anticancer activities .

HY-N1373A

d-Sophoridine (+)-Sophoridine	Apoptosis	Cancer
d-Sophoridine ((+)-Sophoridine) is the dextro isoform of Sophoridine (HY-N1373), which is a quinolizidine alkaloid isolated from Leguminous plant Sophora flavescens. Sophoridine induces apoptosis. Sophoridine has the potential to be a novel, potent and selective antitumor agent candidate for pancreatic cancer with well-tolerated toxicity .

HY-N0746R

Oxysophocarpine (Standard)	Others	Cancer
Oxysophocarpine (Standard) is the analytical standard of Oxysophocarpine. This product is intended for research and analytical applications. Oxysophocarpine is an alkaloid extracted from Sophora alopecuroides. Oxysophocarpine has neuroprotective and anti-nociceptive effects on the central and peripheral nervous systems . Oxysophocarpine inhibits the growth and metastasis of oral squamous cell carcinoma (OSCC) .

HY-N1373R

Sophoridine (Standard)	Apoptosis	Cancer
Sophoridine (Standard) is the analytical standard of Sophoridine. This product is intended for research and analytical applications. Sophoridine is a quinolizidine alkaloid isolated from Leguminous plant Sophora flavescens. Sophoridine induces apoptosis. Sophoridine has the potential to be a novel, potent and selective antitumor agent candidate for pancreatic cancer with well-tolerated toxicity .

HY-N0158R

Oxymatrine (Standard)	TGF-beta/Smad Apoptosis	Infection Inflammation/Immunology Cancer
Oxymatrine (Standard) is the analytical standard of Oxymatrine. This product is intended for research and analytical applications. Oxymatrine, an alkaloid from Sophora flavescens Alt. with anti-inflammatory, antifibrosis, and antitumor effects, inhibits the iNOS expression and TGF-β/Smad pathway. Oxymatrine inhibits bocavirus minute virus of canines (MVC) replication, reduces viral gene expression and decreases apoptosis induced by viral infection.

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