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Results for "

Sophora

" in MedChemExpress (MCE) Product Catalog:

58

Inhibitors & Agonists

58

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N5096
    Sophorabioside

    		Others Others
    Sophorabioside is a flavonoid-glycoside isolated from Sophora japonica .
    Sophorabioside
  • HY-N2529
    Sophoranone

    (-)-Sophoranone; Sophoranon

    		 Others Neurological Disease
    Sophoranone is a flavonoid compound that can be isolated from the root of Sophora subprostrata .
    Sophoranone
  • HY-N1231
    Sophoraflavanone G
    1 Publications Verification

    Kushenol F

    		 Apoptosis Cancer
    Sophoraflavanone G (Kushenol F) is iaolated from Sophora flavescens and shows anti-tumor and anti-inflammatory properties.? Sophoraflavanone G (Kushenol F) induces MDA-MB-231 and HL-60 cells apoptosis through suppression of MAPK-related pathways .
    Sophoraflavanone G
  • HY-N8998
    Sophoraflavanone I

    		Others Others
    Sophoraflavanone I the seeds of Sophora moorcroftiana BENTH. ex. BAKER (Leguminosae) .
    Sophoraflavanone I
  • HY-N8827
    Sophoracarpan A

    		Others Others
    Sophoracarpan A is a Flavonoids product that can be isolated from the aerial parts of Sophora tomentosa L. .
    Sophoracarpan A
  • HY-N8964
    Sophoraflavanone H

    		Others Others
    Sophoraflavanone H is a Flavonoids product that can be isolated from the roots of Sophora moorcroftiana. .
    Sophoraflavanone H
  • HY-N1231R
    Sophoraflavanone G (Standard)

    		Apoptosis Cancer
    Sophoraflavanone G (Standard) is the analytical standard of Sophoraflavanone G. This product is intended for research and analytical applications. Sophoraflavanone G (Kushenol F) is iaolated from Sophora flavescens and shows anti-tumor and anti-inflammatory properties. Sophoraflavanone G (Kushenol F) induces MDA-MB-231 and HL-60 cells apoptosis through suppression of MAPK-related pathways .
    Sophoraflavanone G (Standard)
  • HY-N13187
    7,3'-Dihydroxy flavonone-4'-O-β-D-glucopyranoside

    		Others Others
    7,3'-Dihydroxy flavonone-4'-O-β-D-glucopyranoside is derivated from the seeds of Sophora alopecuroides L. .
    7,3'-Dihydroxy flavonone-4'-O-β-D-glucopyranoside
  • HY-N7806
    7,3'-Di-O-Methylorobol

    		Others Others
    7,3'-Di-O-Methylorobol is a flavone that can be isolated from Sophora japonica .
    7,3'-Di-O-Methylorobol
  • HY-N1344
    Robtin

    		Others Cardiovascular Disease
    Robtin (Compound 4) is a natural product isolated and purified from Sophora yunnanensis. Robtin has cardiotonic activity .
    Robtin
  • HY-N8095
    Kushenol N

    		Others Cardiovascular Disease
    Kushenol N is a prenylated flavonoid that can be isolated from the root of Sophora flavescens. Kushenol N has anti-allergic and vasorelaxation activities .
    Kushenol N
  • HY-N8097
    Kushenol W

    		Bacterial Infection
    Kushenol W is a prenylated flavonoid that can be isolated from the root of Sophora flavescens. Kushenol W has antimicrobial effect, with a MIC of 10 μg/mL for Staphylococcus aureus .
    Kushenol W
  • HY-N5009
    Thermopsine

    		Bacterial Infection
    Thermopsine is a quinolizidine alkaloid isolated from the fruits and pods and stem bark of Sophora velutina subsp. Thermopsine has antibacterial activity .
    Thermopsine
  • HY-121381
    Kuraridine

    		Phosphodiesterase (PDE) Others
    Kuraridine is a prenylated flavonol extract from the roots of Sophora flavescens. Kuraridine has an inhibitory effect on cGMP specific phosphodiesterase type 5 (PDE5) (IC50=0.64 μM) .
    Kuraridine
  • HY-N2779
    8-Lavandulylkaempferol

    		Others Cancer
    8-Lavandulylkaempferol is a flavonoid that can be isolated from Sophora flaWescens. 8-Lavandulylkaempferol exhibits cytotoxic activity against the KB epidermoid carcinoma cell line with an IC50 of 15.1 μg/mL .
    8-Lavandulylkaempferol
  • HY-N2286
    Kushenol I
    1 Publications Verification

    		 Others Inflammation/Immunology
    Kushenol I is a natural compound isolated from the roots of Sophora flavescens .
    Kushenol I
  • HY-N1287
    Sepinol

    		Others Others
    Sepinol is a Flavonoids product that can be isolated from the herbs of Sophora viciifolia .
    Sepinol
  • HY-N1574
    Puerol A

    		Others Others
    Puerol A is a Phenols product that can be isolated from the stem barks of Sophora japonica. .
    Puerol A
  • HY-N10787
    Methylkushenol C

    		Others Others
    Methylkushenol C is a phenolic substance. Methylkushenol C can be isolated from Sophora flavescens .
    Methylkushenol C
  • HY-N9131
    6-Methylgenistein

    		Others Others
    6-Methylgenistein is a Flavonoids product that can be isolated from the roots of Sophora dunnii. .
    6-Methylgenistein
  • HY-N2847
    alpha-Isowighteone

    		Others Others
    alpha-Isowighteone is a Flavonoids product that can be isolated from the roots of Sophora flavescens .
    alpha-Isowighteone
  • HY-N11671
    9α-Hydroxymatrine

    		Others Others
    9α-Hydroxymatrine is a quinolizidine alkaloid that can be found in the leaves of Sophora macrocarpa .
    9α-Hydroxymatrine
  • HY-13516
    Aloperine
    4 Publications Verification

    		 Apoptosis Autophagy Filovirus HIV Infection Inflammation/Immunology Cancer
    Aloperine is an alkaloid in sophora plants such as Sophora alopecuroides L, which has shown anti-cancer, anti-inflammatory and anti-virus properties . Aloperine is widely used to treat patients with allergic contact dermatitis eczema and other skin inflammation in China . Aloperine induces apoptosis and autophagy in HL-60 cells .
    Aloperine
  • HY-N8899
    Daidzein-4'-glucoside

    		Others Others
    Daidzein-4'-glucoside is a Flavonoids product that can be isolated from the fruits of Sophora japonica L. .
    Daidzein-4'-glucoside
  • HY-N0423
    Sophoricoside
    2 Publications Verification

    		 Others Inflammation/Immunology Cancer
    Sophoricoside is an isoflavone glycoside isolated from Sophora japonica and has anti-inflammatory, anti-cancer and immunosuppressive effects.
    Sophoricoside
  • HY-N9083
    8α-Hydroxy-α-gurjunene

    		Others Others
    8α-Hydroxy-α-gurjunene is a Flavonoids product that can be isolated from the aerial parts of Sophora tomentosa L. .
    8α-Hydroxy-α-gurjunene
  • HY-122933
    Kurarinol

    		Tyrosinase Apoptosis Cardiovascular Disease Cancer
    Kurarinol is a flavanone found in the root of Sophora flavescens. Kurarinol is a competitive tyrosinase inhibitor, with IC50 of 0.1 μM for mushroom tyrosinase .
    Kurarinol
  • HY-N6051
    (-​)​-Maackiain

    		Fungal Infection
    (-)-Maackiain is a pterocarpan phytoalexin produced from Sophora flavescens. (-)-Maackiain is toxic to several genera of fungal pathogens of legume and non legume hosts .
    (-​)​-Maackiain
  • HY-N0050
    Allomatrine

    (+)-Allomatrine

    		 Others Neurological Disease
    Allomatrine ((+)-Allomatrine) is an alkaloid from the bark of Sophora japonica. Allomatrine has antinociceptive properties mediated mainly through the activation ofκ-opioid receptors .
    Allomatrine
  • HY-N0423R
    Sophoricoside (Standard)

    		Others Inflammation/Immunology Cancer
    Sophoricoside (Standard) is the analytical standard of Sophoricoside. This product is intended for research and analytical applications. Sophoricoside is an isoflavone glycoside isolated from Sophora japonica and has anti-inflammatory, anti-cancer and immunosuppressive effects.
    Sophoricoside (Standard)
  • HY-N8094
    Kushenol M

    		Cytochrome P450 Others
    Kushenol M is a flavonoid from Sophora flavescens. Kushenol M is a cytochrome P450 (CYP) inhibitor, with IC50 values of 1.29 μM for CYP3A4 in human liver microsomes .
    Kushenol M
  • HY-N5143
    (2R)-3α,7,4'-Trihydroxy-5-methoxy-8-prenylflavanone

    		Others Others
    (2R)-3α,7,4'-Trihydroxy-5-methoxy-8-prenylflavanone is isolated from the roots of Sophora flavescens .
    (2R)-3α,7,4'-Trihydroxy-5-methoxy-8-prenylflavanone
  • HY-N0616
    Trifolirhizin

    		TNF Receptor Tyrosinase Inflammation/Immunology Cancer
    Trifolirhizin is a pterocarpan flavonoid isolated from the roots of Sophora flavescens. Trifolirhizin possesses potent tyrosinase inhibitory activity with an IC50 of 506 μM . Trifolirhizin exhibits potential anti-inflammatory and anticancer activities .
    Trifolirhizin
  • HY-N1402
    Oxysophoridine

    Sophoridine N-oxide

    		 Apoptosis Inflammation/Immunology
    Oxysophoridine (Sophoridine N-oxide) is a bioactive alkaloid extracted from the Sophora alopecuroides Linn. Oxysophoridine (Sophoridine N-oxide) shows anti inflammatory, anti oxidative stress and anti apoptosis effects .
    Oxysophoridine
  • HY-N3414
    Kushenol L

    		Others Metabolic Disease
    Kushenol L is one of the main components of EtOA cextracts from Kushen, a traditional medicinal herb derived from the dried roots of Sophora flavescens Ait. Kushenol L is a flavonoid and plays an important role in anti-diabeticeffects .
    Kushenol L
  • HY-N1373
    Sophoridine
    3 Publications Verification

    		 Apoptosis Cancer
    Sophoridine is a quinolizidine alkaloid isolated from Leguminous plant Sophora flavescens. Sophoridine induces apoptosis. Sophoridine has the potential to be a novel, potent and selective antitumor agent candidate for pancreatic cancer with well-tolerated toxicity .
    Sophoridine
  • HY-N0746
    Oxysophocarpine
    4 Publications Verification

    		 Others Cancer
    Oxysophocarpine is an alkaloid extracted from Sophora alopecuroides.?Oxysophocarpine has neuroprotective and anti-nociceptive effects on the central and peripheral nervous systems . Oxysophocarpine inhibits the?growth?and?metastasis?of ?oral?squamous?cell?carcinoma?(OSCC) .
    Oxysophocarpine
  • HY-N6051R
    (-​)​-Maackiain (Standard)

    		Fungal Infection
    (-)?-Maackiain (Standard) is the analytical standard of (-)?-Maackiain. This product is intended for research and analytical applications. (-)-Maackiain is a pterocarpan phytoalexin produced from Sophora flavescens. (-)-Maackiain is toxic to several genera of fungal pathogens of legume and non legume hosts .
    (-​)​-Maackiain (Standard)
  • HY-N5129
    Genistein 7-O-β-D-glucopyranoside-4'-O-[α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranoside]

    		Others Others
    Genistein 7-O-β-D-glucopyranoside-4'-O-[α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranoside] is an isoflavone triglycoside that could be isolated from Sophora japonica .
    Genistein 7-O-β-D-glucopyranoside-4'-O-[α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranoside]
  • HY-N2463
    Kushenol E
    1 Publications Verification

    		 Indoleamine 2,3-Dioxygenase (IDO) Cancer
    Kushenol E is a class of flavonoids isolated from Sophora flavescens and is a non-competitive indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor with an IC50 of 7.7 µM and a Ki of 9.5 µM, has anti-tumor activity .
    Kushenol E
  • HY-108966
    Kushenol C

    		Beta-secretase Inflammation/Immunology
    Kushenol C, isolated from the roots of Sophora flavescens, shows anti-Inflammatory and anti-oxidative stress activities. Kushenol C inhibits BACE1 (β-site APP cleaving enzyme 1) with an IC50 of 5.45 µM .
    Kushenol C
  • HY-N3413
    Kushenol X

    		Carboxylesterase (CES) β-glucuronidase Metabolic Disease
    Kushenol X, a flavonoid compound isolated from the roots of Sophora flavescens. Kushenol X is a potent β-glucuronidase and human carboxylesterase 2 (hCE2) inhibitor with IC50s of 2.07 μM and 3.05 μM, respectively .
    Kushenol X
  • HY-N8228
    17-Hydroxyneomatrine

    		Bacterial Infection Inflammation/Immunology Cancer
    17-Hydroxyneomatrine, extracted from Sophora flavescens, can well inhibit the growth of human cervical carcinoma Hela cells, has the wide-range antibacterial, anti-allergy, anti-tumor, anti-arrhythmia, swelling-subsiding diuresis, immunizing, and biological regulation functions .
    17-Hydroxyneomatrine
  • HY-N0158
    Oxymatrine
    Maximum Cited Publications
    16 Publications Verification

    		 TGF-beta/Smad Apoptosis Infection Inflammation/Immunology Cancer
    Oxymatrine, an alkaloid from Sophora flavescens Alt. with anti-inflammatory, antifibrosis, and antitumor effects, inhibits the iNOS expression and TGF-β/Smad pathway. Oxymatrine inhibits bocavirus minute virus of canines (MVC) replication, reduces viral gene expression and decreases apoptosis induced by viral infection.
    Oxymatrine
  • HY-N0616R
    Trifolirhizin (Standard)

    		TNF Receptor Tyrosinase Inflammation/Immunology Cancer
    Trifolirhizin (Standard) is the analytical standard of Trifolirhizin. This product is intended for research and analytical applications. Trifolirhizin is a pterocarpan flavonoid isolated from the roots of Sophora flavescens. Trifolirhizin possesses potent tyrosinase inhibitory activity with an IC50 of 506 μM . Trifolirhizin exhibits potential anti-inflammatory and anticancer activities .
    Trifolirhizin (Standard)
  • HY-N1373A
    d-Sophoridine

    (+)-Sophoridine

    		 Apoptosis Cancer
    d-Sophoridine ((+)-Sophoridine) is the dextro isoform of Sophoridine (HY-N1373), which is a quinolizidine alkaloid isolated from Leguminous plant Sophora flavescens. Sophoridine induces apoptosis. Sophoridine has the potential to be a novel, potent and selective antitumor agent candidate for pancreatic cancer with well-tolerated toxicity .
    d-Sophoridine
  • HY-N1373R
    Sophoridine (Standard)

    		Apoptosis Cancer
    Sophoridine (Standard) is the analytical standard of Sophoridine. This product is intended for research and analytical applications. Sophoridine is a quinolizidine alkaloid isolated from Leguminous plant Sophora flavescens. Sophoridine induces apoptosis. Sophoridine has the potential to be a novel, potent and selective antitumor agent candidate for pancreatic cancer with well-tolerated toxicity .
    Sophoridine (Standard)
  • HY-N0746R
    Oxysophocarpine (Standard)

    		Others Cancer
    Oxysophocarpine (Standard) is the analytical standard of Oxysophocarpine. This product is intended for research and analytical applications. Oxysophocarpine is an alkaloid extracted from Sophora alopecuroides. Oxysophocarpine has neuroprotective and anti-nociceptive effects on the central and peripheral nervous systems . Oxysophocarpine inhibits the growth and metastasis of oral squamous cell carcinoma (OSCC) .
    Oxysophocarpine (Standard)
  • HY-N0158R
    Oxymatrine (Standard)

    		TGF-beta/Smad Apoptosis Infection Inflammation/Immunology Cancer
    Oxymatrine (Standard) is the analytical standard of Oxymatrine. This product is intended for research and analytical applications. Oxymatrine, an alkaloid from Sophora flavescens Alt. with anti-inflammatory, antifibrosis, and antitumor effects, inhibits the iNOS expression and TGF-β/Smad pathway. Oxymatrine inhibits bocavirus minute virus of canines (MVC) replication, reduces viral gene expression and decreases apoptosis induced by viral infection.
    Oxymatrine (Standard)
  • HY-N6052
    (+)-Medicarpin

    		Estrogen Receptor/ERR Cancer
    (+)-Medicarpin, a pterocarpan, is a type of isoflavonoid isolated from several medicinal plant species with various biological effects, including Sophora japonica, Zollernia paraensis and Platymiscium yucatamun, Machaerium aristulatum, Platymiscium floribundum, and so on. (+)-Medicarpin potently inhibits osteoclastogenesis and promotes bone healing and increases bone mass by osteoblast differentiation with estrogen receptor (ER) β-mediated osteogenic action .
    (+)-Medicarpin

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