2. Search Result
Search Result
Results for "

aged skin

" in MedChemExpress (MCE) Product Catalog:

27

Inhibitors & Agonists

2

Biochemical Assay Reagents

9

Peptides

11

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-164159
    α-Glucosylrutin

    		Reactive Oxygen Species Inflammation/Immunology
    α-Glucosylrutin is a potent antioxidant with free radical scavenging activity. Due to its high epidermal bioavailability, α-Glucosylrutin can be used in the study of skin aging .
    α-Glucosylrutin
  • HY-N3127
    Orobol

    		Casein Kinase PI3K VEGFR Metabolic Disease
    Orobol is one of the major soy isoflavones and has various pharmacological activities, including anti-skin-aging and anti-obesity effects. Orobol inhibits CK1ε, VEGFR2, MAP4K5, MNK1, MUSK, TOPK, and TNIK (IC50=1.24-4.45 μM). Orobol also inhibits PI3K isoforms (IC50=3.46-5.27 μM for PI3K α/β/γ/K/δ) .
    Orobol
  • HY-P3163
    Hexapeptide-9

    		Biochemical Assay Reagents Others
    Hexapeptide-9 is a collagen peptide, with anti-aging activity. Hexapeptide-9 is commonly used as the ingredient in skin care products for improving the appearance of the skin .
    Hexapeptide-9
  • HY-N15152
    Isoaesculioside D

    		Others Metabolic Disease
    Isoaesculioside D (compound 3) is an agent for preventing or ameliorating skin aging. Isoaesculioside D exhibits an excellent effect on the suppression of formation, or the amelioration, of wrinkles on the skin or sagging skin .
    Isoaesculioside D
  • HY-164066
    Sodium Acetylated Hyaluronate

    		Biochemical Assay Reagents Others
    Sodium Acetylated Hyaluronate is an acetylated hyaluronic acid derivative with anti-wrinkle and deep skin penetration properties, which can be used in skin aging research and cosmetic development .
    Sodium Acetylated Hyaluronate
  • HY-N3612
    Communic acid

    (+)-Communic acid

    		 Bacterial Akt MMP Infection Inflammation/Immunology
    Communic acid ((+)-Communic acid) is a natural compound isolated from the branches of Platycladus orientalis. Communic acid displays minimum inhibitory concentration of 31 μM and IC50 of 15 μM against M. tuberculosis H37Ra.Communic acid exhibits protective effects against UVB-induced skin aging .
    Communic acid
  • HY-W127738
    6-O-Stearoyl-L-ascorbic acid

    Vitamin C stearate; Ascorbic acid 6-stearate; Ascorbyl stearate

    		 Biochemical Assay Reagents Others
    6-O-Staroyl-L-ascorbic acid is an organic compound commonly used in cosmetics and skin care products. It can be used as an antioxidant and whitening agent, and is widely used in anti-aging, moisturizing and skin repairing. In addition, this compound is used as a catalyst or buffer in certain chemical reactions.
    6-O-Stearoyl-L-ascorbic acid
  • HY-N13232
    Grape Skin Extract

    		Amyloid-β Neurological Disease
    Grape Skin Extract is a grape skin extract, and its ingredients include: Polyphenols. Grape Skin Extract has neuroprotective effects and can improve Aβ-induced cytotoxicity to SH-SY5Y cells. Grape Skin Extract can increase the proliferation and memory of neurogenic areas, but reduce the oxidative stress associated with proinflammatory cytokines during aging, thereby protecting neurons. .
    Grape Skin Extract
  • HY-N13299
    Glucoberteroin

    		Endogenous Metabolite Others
    Glucoberteroin is a glucosinolate, which could be isolated from Degenia velebitica. Glucoberteroin inhibits protein glycosylation and carbonylation, decreases the production of carbonyl protein, and contributes to the preventation of skin-aging .
    Glucoberteroin
  • HY-169085
    LRAT-IN-1

    		Acyltransferase Metabolic Disease
    LRAT-IN-1 (compound 1) is a retinol acyltransferase (LRAT) inhibitor (IC50=21.1 μM). LRAT-IN-1 provides anti-aging effects by inhibiting the esterification of retinol to form retinol esters, increasing the available retinol in the skin. Research on LRAT-IN-1 as an anti-aging ingredient in cosmetics .
    LRAT-IN-1
  • HY-P0095
    Acetyl tetrapeptide-5

    		Angiotensin-converting Enzyme (ACE) Others
    Acetyl tetrapeptide-5 inhibits glycosylation and ACE-1 activity. Acetyl tetrapeptide-5 reduces edema and relieves vascular pressure by improving the vascular system and strengthening the skin under the eyes. Acetyl tetrapeptide-5 can be used in the research of Antioxidant, anti-aging skin care .
    Acetyl tetrapeptide-5
  • HY-W997836
    4-Amino-3-hydroxyphenylalanine

    4-AHP

    		 Endogenous Metabolite Cancer
    4-Amino-3-hydroxyphenylalanine (4-AHP) is a photodegradation product of Eumelanin. 4-Amino-3-hydroxyphenylalanine can be used for research of melanomagenesis in the skin and age-related macular degeneration .
    4-Amino-3-hydroxyphenylalanine
  • HY-P0033A
    Argireline acetate

    Acetyl hexapeptide-3 acetate

    		 Calcium Channel Neurological Disease
    Argireline acetate (Acetyl hexapeptide-3 acetate) is a non-toxic, skin-permeable, antiwrinkle peptide. Argireline acetate significantly inhibits Ca 2+ dependent neurotransmitter release (acetylcholine) at the neuromuscular junction. Argireline acetate has antiwrinkle and anti-aging activity .
    Argireline acetate
  • HY-P0033
    Argireline

    Acetyl hexapeptide-3

    		 Calcium Channel Neurological Disease
    Argireline (Acetyl hexapeptide-3) is a non-toxic, skin-permeable, antiwrinkle peptide. Argireline significantly inhibits Ca 2+ dependent neurotransmitter release (acetylcholine) at the neuromuscular junction. Argireline has antiwrinkle and anti-aging activity .
    Argireline
  • HY-108036
    Pro-xylane (30% in water)

    Hydroxypropyl tetrahydropyrantriol

    		 Biochemical Assay Reagents Metabolic Disease
    Pro-xylane (30% in water) (Hydroxypropyl tetrahydropyrantriol) is a biologically active C-glycoside in aqueous media, acts as an activator of glycosaminoglycans (GAGs) biosynthesis. Pro-xylane (30% in water) has potential skin anti-aging properties and is eco-friendly, biodegradable, and can be used in cosmetic research .
    Pro-xylane (30% in water)
  • HY-N1420
    Rhamnose

    L-Rhamnose

    		 Endogenous Metabolite MMP Interleukin Related PKA Cancer
    Rhamnose (L-Rhamnose) is an orally active deoxysugar that is widely found in plants and bacteria. Rhamnose can inhibit levels of pro-inflammatory interleukin and matrix metalloproteinases (MMPs) in skin aging models, showing anti-aging effects. Rhamnose can promote the phosphorylation levels of PKA substrates and HSL in SVF-derived adipocytes, stimulating PKA signaling. Rhamnose can act against obesity in mice by stimulating fat dopamine receptors and inducing thermogenesis. Rhamnose is also used in cancer research .
    Rhamnose
  • HY-P3164
    Acetyl tetrapeptide-9

    AcTP1

    		 Biochemical Assay Reagents Others
    Caprooyl-tetrapeptide-9 (AcTP1) is a bioactive peptide with anti-aging effect and has been reported used as a cosmetic ingredient .
    Acetyl tetrapeptide-9
  • HY-108036A
    (S)-Pro-xylane

    (S)-Hydroxypropyl tetrahydropyrantriol

    		 Biochemical Assay Reagents Others
    (S)-Pro-xylane ((S)-Hydroxypropyl tetrahydropyrantriol) is the S-enantiomer of Pro-xylane (HY-108036). Pro-xylane (Hydroxypropyl tetrahydropyrantriol) is a biologically active C-glycoside in aqueous media, acts as an activator of glycosaminoglycans (GAGs) biosynthesis. Pro-xylane has potential skin anti-aging properties and is eco-friendly, biodegradable, and can be used in cosmetic research .
    (S)-Pro-xylane
  • HY-P0064
    Palmitoyl Tetrapeptide-3

    Palmitoyl Tetrapeptide-7

    		 Interleukin Related Inflammation/Immunology
    Palmitoyl Tetrapeptide-3 (Palmitoyl Tetrapeptide-7) is a synthetic peptide corresponding to amino acids 341-344 of the human immunoglobulin heavy chain, with the ability to stimulate phagocytosis. Palmitoyl tetrapeptide-3 reduces interleukin-6 (IL-6) secretion in keratinocytes and inhibits the UVB radiation-exposure inflammatory response of skin. Palmitoyl tetrapeptide-3 It also has anti-inflammatory and anti-aging effects, reducing skin wrinkles by promoting the production of elastic fibers in the papillary dermis .
    Palmitoyl Tetrapeptide-3
  • HY-N1190
    DL-Syringaresinol

    (±)-Syringaresinol

    		 p38 MAPK AP-1 Bacterial Infection
    DL-Syringaresinol ((±)-Syringaresinol), a lignin, inhibits UVA-induced upregulation of MMP-1 by suppressing MAPK/AP-1 signaling in human HaCaT keratinocytes and dermal fibroblasts (HDFs). DL-Syringaresinol has antiphotoaging properties against UVA-induced skin aging. DL-Syringaresinol exhibits weak antimycobacterial activity against Mycobacterium tuberculosis H37Rv .
    DL-Syringaresinol
  • HY-168957
    RuDiOBn

    		MMP Reactive Oxygen Species Others
    RuDiOBn scanvages DPPH and ABTS free radicals (13.2% and 5.9% clearance at 100 μg/mL), exhibits low antioxidant activity. RuDiOBn inhibits the collagen glycation, reduces the formation of advanced glycation end products (AGEs) with an IC50 of 2.45 μg/mL. RuDiOBn enhances the proliferation and migration of fibroblasts, stimulates the synthesis of collagen, promoting the skin repair and regeneration. RuDiOBn also inhibits collagenase .
    RuDiOBn
  • HY-NP162
    Recombinant Humanized Type XVII Collagen

    		Biochemical Assay Reagents Others
    Recombinant Humanized Type XVII Collagen is a transmembrane protein that forms hemidesmosomes. Recombinant Humanized Type XVII Collagen facilitates interactions between stem cells，surrounding cells，and the extracellular matrix，thereby regulating skin homeostasis，aging，and wound healing. Recombinant Humanized Type XVII Collagen also possesses unique cell adhesion sites and signal transduction functions，which can regulate cell migration，proliferation，and differentiation .
    Recombinant Humanized Type XVII Collagen
  • HY-N2278
    Kushenol A
    1 Publications Verification

    Leachianone E

    		 Tyrosinase Glycosidase Cancer
    Kushenol A (Leachianone E) is isolated from the root of Sophora flavescent. Kushenol A is a non-competitive tyrosinase inhibitor to block the conversion of L-tyrosine to L-DOPA, shows IC50 and Kivalues of 1.1 μM and 0.4 μM, respectively . Kushenol A is a flavonoid antioxidant, has inhibitory effects on alpha-glucosidase (IC50: 45 μM; Ki: 6.8 μM) and β-amylase . Kushenol A is confirmed as potential inhibitors of enzymes targeted by cosmetics for skin whitening and aging .
    Kushenol A
  • HY-N6818
    5,​7,​4'-​Trimethoxyflavone

    MTF

    		 Apoptosis Caspase PARP Endogenous Metabolite CFTR Cancer
    5,7,4’-Trimethoxyflavone can be isolated from the medicinal plant Kaempferia parviflora (KP). 5,7,4’-Trimethoxyflavone is a CFTR activator and EC50 is 64 μM. 5,7,4’-Trimethoxyflavone induces apoptosis, increases proteolytic activation of caspase-3, and degradation of ADP-ribose polymerase (PARP) protein. 5,7,4’-Trimethoxyflavone has antitumor activity. 5,7,4’-Trimethoxyflavone can be used to prevent skin aging and oxidative stress .
    5,​7,​4'-​Trimethoxyflavone
  • HY-N0568
    Madecassoside

    Asiaticoside A

    		 Endogenous Metabolite Apoptosis Autophagy Keap1-Nrf2 p38 MAPK Caspase Cardiovascular Disease Others Neurological Disease Inflammation/Immunology Endocrinology Cancer
    Madecassoside is a pentacyclic triterpene isolated from Centella asiatica and has anti-inflammatory properties. Antioxidant and anti-aging effects. Madecassoside is a pentacyclic triterpene isolated from Centella asiatica. Madecassoside is orally active and has inhibitory properties against inflammation, oxidation, apoptosis and autophagy. Madecassosid inhibits activities of p38 MAPK and NF-kB [5][6], exhibits an anti-apopototic property, activates Nrf2 expression to reduce the neurotoxicity . Madecassoside can be used in endocrine diseases, cardiovascular diseases, skin diseases and other diseases.
    Madecassoside
  • HY-N0568R
    Madecassoside (Standard)

    		Endogenous Metabolite Apoptosis Autophagy Keap1-Nrf2 p38 MAPK Caspase Cardiovascular Disease Others Neurological Disease Inflammation/Immunology Endocrinology Cancer
    Madecassoside (Standard) is the analytical standard of Madecassoside. This product is intended for research and analytical applications. Madecassoside is a pentacyclic triterpene isolated from Centella asiatica and has anti-inflammatory properties. Antioxidant and anti-aging effects. Madecassoside is a pentacyclic triterpene isolated from Centella asiatica. Madecassoside is orally active and has inhibitory properties against inflammation, oxidation, apoptosis and autophagy. Madecassosid inhibits activities of p38 MAPK and NF-kB , exhibits an anti-apopototic property, activates Nrf2 expression to reduce the neurotoxicity[10]. Madecassoside can be used in endocrine diseases, cardiovascular diseases, skin diseases and other diseases.
    Madecassoside (Standard)
  • HY-N6818R
    5,​7,​4'-​Trimethoxyflavone (Standard)

    MTF (Standard)

    		 Apoptosis Caspase PARP Endogenous Metabolite CFTR Cancer
    5,?7,?4'-Trimethoxyflavone (Standard) is the analytical standard of 5,?7,?4'-Trimethoxyflavone. This product is intended for research and analytical applications. 5,7,4’-Trimethoxyflavone can be isolated from the medicinal plant Kaempferia parviflora (KP). 5,7,4’-Trimethoxyflavone is a CFTR activator and EC50 is 64 μM. 5,7,4’-Trimethoxyflavone induces apoptosis, increases proteolytic activation of caspase-3, and degradation of ADP-ribose polymerase (PARP) protein. 5,7,4’-Trimethoxyflavone has antitumor activity. 5,7,4’-Trimethoxyflavone can be used to prevent skin aging and oxidative stress .
    5,​7,​4'-​Trimethoxyflavone (Standard)

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

  

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

  

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: