Search Result

Results for "

aminopeptidase

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Aminopeptidase (37) MetAP (7) Amino Acid Derivatives (1) Antibiotic (9) Apoptosis (3) Bacterial (11) Biochemical Assay Reagents (5) Bradykinin Receptor (1) Dipeptidyl Peptidase (5) Endogenous Metabolite (2) Endothelin Receptor (1) Epoxide Hydrolase (1) Fluorescent Dye (3) GCGR (3) GLP Receptor (2) GnRH Receptor (1) Isotope-Labeled Compounds (1) Leukotriene Receptor (2) Lipase (1) MMP (1) Neprilysin (2) Nucleoside Antimetabolite/Analog (1) Opioid Receptor (1) Parasite (2) Phosphatase (1) Prolyl Endopeptidase (PREP) (1) Renin (1) Somatostatin Receptor (3)
By Research Areas:	Cancer (24) Cardiovascular Disease (9) Endocrinology (3) Infection (14) Inflammation/Immunology (8) Metabolic Disease (14) Neurological Disease (13)

By Targets:

Aminopeptidase (37)

MetAP (7)

Amino Acid Derivatives (1)

Antibiotic (9)

Apoptosis (3)

Bacterial (11)

Biochemical Assay Reagents (5)

Bradykinin Receptor (1)

Dipeptidyl Peptidase (5)

Endogenous Metabolite (2)

Endothelin Receptor (1)

Epoxide Hydrolase (1)

Fluorescent Dye (3)

GCGR (3)

GLP Receptor (2)

GnRH Receptor (1)

Isotope-Labeled Compounds (1)

Leukotriene Receptor (2)

Lipase (1)

MMP (1)

Neprilysin (2)

Nucleoside Antimetabolite/Analog (1)

Opioid Receptor (1)

Parasite (2)

Phosphatase (1)

Prolyl Endopeptidase (PREP) (1)

Renin (1)

Somatostatin Receptor (3)

By Research Areas:

Cancer (24)

Cardiovascular Disease (9)

Endocrinology (3)

Infection (14)

Inflammation/Immunology (8)

Metabolic Disease (14)

Neurological Disease (13)

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Targets Recommended: Aminopeptidase MetAP

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-151518

Aminopeptidase-IN-1	Aminopeptidase	Neurological Disease
Aminopeptidase-IN-1 (compound 16o) is a potent *insulin-regulated aminopeptidase* (IRAP) inhibitor with an K_i** value of 7.7 μM. Aminopeptidase-IN-1 can be used tor research cognitive and memory impairments .

HY-P2779

*Microsomal aminopeptidase, Microorganism*	Endogenous Metabolite	Metabolic Disease
Microsomal aminopeptidase, Microorganism is first reported from C. elegans. The Microsomal aminopeptidase, Microorganism is beneficial for the development of molecular vaccines against parasitic nematodes .

HY-137528

H-Glu(4MβNA)-OH H-Glu(4MbetaNA)-OH; L-Glutamic acid γ-(4-methoxy-β-naphthylamide)	Others	Others
H-Glu(4MβNA)-OH is a substrate of aminopeptidases (APs) .

HY-P2842

*Aminopeptidase*	Others	Others Cancer
Aminopeptidase catalyzes the cleavage of amino acids from the amino terminus of protein or peptide substrates .

HY-P4205

Aminopeptidase N Ligand (CD13) NGR peptide	Aminopeptidase	Cancer
Aminopeptidase N Ligand (CD13) NGR peptide is a polypeptide targeting CD13 and can be used as a carrier to mediate intracellular transmission. Aminopeptidase N Ligand (CD13) NGR peptide is often used in cancer research .

HY-E70199

Aminopeptidase N (rat) APN/CD13	Others	Others
A Aminopeptidase N (rat) (APN/CD13) is a Zn ²⁺ dependent membrane-bound ectopeptidase that degrades preferentially proteins and peptides with a N-terminal neutral amino acid .

HY-E70128

Leucyl aminopeptidase	Others	Others
Leucyl aminopeptidase is a metallopeptidase that cleave N-terminal residues from proteins and peptides. Leucyl aminopeptidase serves as transcriptional repressors to control pyrimidine, alginate and cholera toxin biosynthesis, as well as mediate site-specific recombination events in plasmids and phages .

HY-108729

Tripeptidyl aminopeptidase Cerliponase alfa	Endogenous Metabolite	Neurological Disease
Tripeptidyl aminopeptidase (Cerliponase alfa) removes tripeptides from the free NH, terminus of longer peptides. Tripeptidyl aminopeptidase has the potential for the research of CLN2 disease .

HY-P2928

Aeromonas proteolytica aminopeptidase	Others	Others
Aeromonas proteolytica aminopeptidase is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-P3174

*Pyroglutamate aminopeptidase* I**	Others	Others
Pyroglutamate aminopeptidase I is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-129298

Amastatin	Aminopeptidase	Others
Amastatin is A slow, tightly bound, competitive inhibitor of aminopeptidase (AP) with an IC₅₀ of 0.54 μg/mL for AP-A .

HY-120868

TP-004	MetAP	Metabolic Disease
TP-004 is a potent and reversible inhibitor of *methionine aminopeptidase* 2 (MetAP2), with an IC₅₀** of 6 nM .

HY-163714

IRAP-IN-1	Aminopeptidase	Metabolic Disease
IRAP-IN-1 (compound 3) is a potent and selective *insulin regulated aminopeptidase* (IRAP) inhibitor with an IC₅₀** value of 157 nM .

HY-117238

Ketomethylenebestatin	Aminopeptidase	Others
Ketomethylenebestatin is an aminopeptidase (AP) inhibitor and an analog of the natural aminopeptidase inhibitor Bestatin (HY-B0134) with IC₅₀ of 56 μM, 752 μM and 0.39 μM for AP-B, AP-M and Leu-AP, respectively .

HY-136614

H-Val-βNA L-Valine β-naphthylamide	Others	Others
H-Val-βNA (L-Valine β-naphthylamide) can be used as an aminopeptidase and a Valine arylamidase substrate .

HY-137928

H-Ala-4MβNA hydrochloride	Fluorescent Dye	Others
H-Ala-4MβNA hydrochloride is a specific fluorogenic substrate for aminopeptidase M .

HY-158410

PSA-IN-1	Others	Neurological Disease
PSA-IN-1 (compound 19) is a *puromycin sensitive aminopeptidase* (PSA) inhibitor with IC₅₀** at 7 nM. PSA-IN-1 has analgesic activity .

HY-D1534

H-L-Ile-Amc TFA	Biochemical Assay Reagents	Others
H-L-Ile-Amc (TFA) is an enzyme substrate, and can detect the yeasts and molds in the sample using aminopeptidase substrates .

HY-133125

ERAP1-IN-1 2 Publications Verification	Others	Inflammation/Immunology
ERAP1-IN-1 is an *endoplasmic reticulum aminopeptidase* 1 (ERAP1)** inhibitor. ERAP1-IN-1 competitively inhibits ERAP1 activity towards a nonamer peptide representative of physiological substrates .

HY-168181

ERAP1-IN-2	Others	Others
ERAP1-IN-2 (compound 3f) is an inhibitor of ERAP1 (endoplasmic reticulum aminopeptidase 1). ERAP1-IN-2 has an IC₅₀ value of 1.72 μM against hERAP1 .

HY-137844

L-Leucine-7-amido-4-methylcoumarin hydrochloride Leu-AMC hydrochloride	Fluorescent Dye	Others
L-Leucine-7-amido-4-methylcoumarin (Leu-AMC) hydrochloride is a bright blue fluorogenic peptidyl substrate for LAP3 (leucine aminopeptidase). L-Leucine-7-amido-4-methylcoumarin hydrochloride can be used for leucine aminopeptidase inhibition assays in vitro .

HY-125422

Matlystatin A	Aminopeptidase	Cancer
Matlystatin A is a potent *aminopeptidase* inhibitor, with IC₅₀ values of 0.3 μM and 0.56 μM against 92 kDa and 72 kDa type IV collagenases, respectively. Matlystatin A can be utilized in cancer research .

HY-156960

JNJ-40929837	Aminopeptidase Leukotriene Receptor	Inflammation/Immunology
JNJ-40929837 is a selective and orally active LTA₄H (leukotriene A₄ hydrolase) inhibitor. JNJ-40929837 effectively inhibits *aminopeptidase* activity and causes serum accumulation of Pro-Gly-Pro. JNJ-40929837 can be used in asthma research .

HY-163727

MMV1557817	Parasite	Infection
MMV1557817 is an orally active and potent antimalarial compound. MMV1557817 is a selective, nanomolar inhibitor of both Plasmodium falciparum and Plasmodium vivax aminopeptidases M1 and M17, leading to inhibition of end-stage hemoglobin digestion in asexual parasites .

HY-156960A

JNJ-40929837 succinate	Aminopeptidase Leukotriene Receptor	Inflammation/Immunology
JNJ-40929837 succinate is a selective and orally active LTA₄H (leukotriene A₄ hydrolase) inhibitor. JNJ-40929837 succinate effectively inhibits *aminopeptidase* activity and causes serum accumulation of Pro-Gly-Pro. JNJ-40929837 succinate can be used in asthma research .

HY-136887

Arphamenine B hemisulfate	Others	Others
Arphamenine B (hemisulfate) is a Zn ²⁺-dependent exopeptidase that selectively removes arginine and/or lysine residues from the NH2-terminus of several peptide substrates. Arphamenine B (hemisulfate) Arphamenine B (hemisulfate) is an inhibitor of aminopeptidase B that can be isolated from bacteria. Arphamenine B (hemisulfate) enhances the immune response and is used to characterize novel proteases .

HY-W717329

EC33	Aminopeptidase	Cardiovascular Disease
EC33 is a selective aminopeptidase A (APA) inhibitor. EC33 blocks the pressor response of exogenous Ang II. EC33 does not cross the blood-brain barrier. EC33 has the potential for salt-dependent model of hypertension research .

HY-115194

Amastatin hydrochloride	Aminopeptidase Bacterial	Infection
Amastatin hydrochloride is a slow, tight binding, competitive aminopeptidase (AP) inhibitor with K_i values of 0.26 nM, 30 nM, 52 nM for Aeromonas aminopeptidase, cytosolic leucine aminopeptidase, microsomal aminopeptidase .

HY-117702

RB 101	Prolyl Endopeptidase (PREP) Aminopeptidase	Metabolic Disease
RB 101 is an active mixed inhibitor against two enzymes which metabolize the enkephalins neutral endopeptidase and aminopeptidase N. RB 101 has rather long-lasting antinociceptive effects. RB 101 inhibits the in vivo [ ³H]DPN binding both under basal conditions and after swim stress in mice. RB 101 can be used to determine the precise in vivo localization of enkephalinergic pathways recruited by various stimuli .

HY-101932

TNP-470 1 Publications Verification AGM-1470	Aminopeptidase	Cardiovascular Disease Cancer
TNP-470 is a methionine aminopeptidase-2 inhibitor and also an angiogenesis inhibitor.

HY-P1044

Spinorphin LVV-hemorphin-4	Others	Neurological Disease
Spinorphin is an inhibitor of enkephalin-degrading enzymes. Spinorphin inhibits aminopeptidase, dipeptidyl aminopeptidase III, angiotensin-converting enzyme and enkephalinase. Spinorphin possesses an antinociceptive effect .

HY-121483

Leucinal	Others	Others
Leucinal is a competitive inhibitor of brain aminopeptidase, inhibits brain soluble aminopeptidase activity (Ki = 22 microM), and can enhance the analgesia induced by leuprorelin, but has no effect on the analgesia induced by some other substances.

HY-13731

PPI-2458	MetAP	Inflammation/Immunology Cancer
PPI-2458 is a potent, orally active, selective and irreversible inhibitor of methionine aminopeptidase-2 (MetAP-2). PPI-2458 can be used for arthritis and lymphoma research .

HY-136542

H-β-Ala-AMC TFA	Others	Cancer
H-β-Ala-AMC TFA is a substrate for aminopeptidase.

HY-W027340

ARM1 1 Publications Verification 4BSA	Aminopeptidase Epoxide Hydrolase	Cancer
ARM1 (4BSA) is a potent *aminopeptidase* and epoxide hydrolase inhibitor. ARM1 shows aminopeptidase inhibitory activity with an IC₅₀ 7.61 µM and epoxide hydrolase inhibitory activity with an IC₅₀ 12.4 µM .

HY-133016A

(R)-M8891	MetAP	Others
(R)-M8891 (compound R-9) is a less active isomer of M8891. M8891 is an orally active, reversible and brain penetrant Methionine Aminopeptidase-2 (MetAP-2) inhibitor .

HY-147401

Sitagliptin fenilalanil	Dipeptidyl Peptidase	Metabolic Disease
Sitagliptin fenilalanil is a *dipeptidyl aminopeptidase* 4 (DPP-4)** inhibitor .

HY-W015876

L-Leucinol (+)-Leucinol	Aminopeptidase	Others
L-Leucinol ((+)-Leucinol) is a competitive *aminopeptidase* inhibitor with K_i value of 17 μM .

HY-147401A

Sitagliptin fenilalanil hydrochloride	Dipeptidyl Peptidase	Metabolic Disease
Sitagliptin fenilalanil hydrochloride is a *dipeptidyl aminopeptidase* 4 (DPP-4)** inhibitor .

HY-16710

GPDA GPN; Glycylproline p-nitroanilide tosylate	Fluorescent Dye	Others
GPDA(Glycylproline p-nitroanilide tosylate) is the substarate of X-Prolyl dipeptidyl-aminopeptidase in the enzyme assay.

HY-137901

L-Alanine 4-nitroanilide hydrochloride, 99% Ala-4-nitroanilide, 99%; H-Ala-pNA, 99%	Biochemical Assay Reagents	Others
L-Alanine 4-nitroanilide hydrochloride, 99% is a detection substrate for L-alanine aminopeptidase.

HY-W011911

L-Leucyl-4-nitroanilide	Biochemical Assay Reagents	Others
L-Leucyl-4-nitroanilide is a colorimetric substrate for leucine aminopeptidase assays.

HY-113952

Actinonin 5 Publications Verification (-)-Actinonin	Aminopeptidase Bacterial MMP Apoptosis Antibiotic	Infection Cancer
Actinonin ((-)-Actinonin) is a naturally occurring antibacterial agent produced by Actinomyces. Actinonin inhibits aminopeptidase M, aminopeptidase N and leucine aminopeptidase. Actinonin is a potent reversible peptide deformylase (PDF) inhibitor with a K_i of 0.28 nM. Actinonin also inhibits MMP-1, MMP-3, MMP-8, MMP-9, and hmeprin α with K_i values of 300 nM, 1,700 nM, 190 nM, 330 nM, and 20 nM, respectively. Actinonin is an apoptosis inducer. Actinonin has antiproliferative and antitumor activities .

HY-110259

HFI-142 1 Publications Verification	Aminopeptidase	Neurological Disease
HFI-142 is an *insulin-regulated aminopeptidase* (IRAP) inhibitor with a K_i** of 2.01 μM .

HY-118661

BDM14471	Aminopeptidase	Others
BDM14471 is a selective inhibitor of hydroxamate aminopeptidase M1 (PfAM1), with the IC₅₀ of 6 nM .

HY-B0134A

Bestatin hydrochloride 5+ Cited Publications Ubenimex hydrochloride	Aminopeptidase Bacterial Antibiotic	Infection Cancer
Bestatin hydrochloride is an inhibitor of *CD13 (Aminopeptidase* N)/APN and leukotriene A4 hydrolase**, used for cancer research.

HY-B0134B

Bestatin trifluoroacetate Ubenimex trifluoroacetate	Aminopeptidase Bacterial Antibiotic	Infection Cancer
Bestatin trifluoroacetate is an inhibitor of *CD13 (Aminopeptidase* N)/APN and leukotriene A4 hydrolase**, used for cancer research.

HY-P4549

H-D-Ala-D-Ala-D-Ala-D-Ala-OH	Aminopeptidase	Others
H-D-Ala-D-Ala-D-Ala-D-Ala-OH is a substrate for D-aminopeptidase .

HY-P1490

Bradykinin (2-9) Des-Arg1-bradykinin	Bradykinin Receptor	Cardiovascular Disease Endocrinology
Bradykinin (2-9) is an amino-truncated Bradykinin peptide. Bradykinin (2-9) is a metabolite of Bradykinin, cleaved by Aminopeptidase P.

HY-137895

L-Arginine p-nitroanilide dihydrochloride, 98% H-Arg-pNA 2HCl, 98%	Biochemical Assay Reagents	Others
L-Arginine p-nitroanilide dihydrochloride, 98% (H-Arg-pNA 2HCl, 98%) is a chromogenic substrate for cathepsin H and aminopeptidases.

Cat. No.	Product Name	Type

HY-137844

L-Leucine-7-amido-4-methylcoumarin hydrochloride Leu-AMC hydrochloride	Fluorescent Dyes/Probes
L-Leucine-7-amido-4-methylcoumarin (Leu-AMC) hydrochloride is a bright blue fluorogenic peptidyl substrate for LAP3 (leucine aminopeptidase). L-Leucine-7-amido-4-methylcoumarin hydrochloride can be used for leucine aminopeptidase inhibition assays in vitro .

HY-16710

GPDA GPN; Glycylproline p-nitroanilide tosylate	Chromogenic Substrates
GPDA(Glycylproline p-nitroanilide tosylate) is the substarate of X-Prolyl dipeptidyl-aminopeptidase in the enzyme assay.

HY-137928

H-Ala-4MβNA hydrochloride	Fluorescent Dyes/Probes
H-Ala-4MβNA hydrochloride is a specific fluorogenic substrate for aminopeptidase M .

Cat. No.	Product Name	Target	Research Area

HY-P1044A

Spinorphin TFA LVV-hemorphin-4 TFA	Peptides	Neurological Disease
Spinorphin TFA is an inhibitor of enkephalin-degrading enzymes. Spinorphin inhibits aminopeptidase, dipeptidyl aminopeptidase III, angiotensin-converting enzyme and enkephalinase. Spinorphin possesses an antinociceptive effect .

HY-P1490

Bradykinin (2-9) Des-Arg1-bradykinin	Bradykinin Receptor	Cardiovascular Disease Endocrinology
Bradykinin (2-9) is an amino-truncated Bradykinin peptide. Bradykinin (2-9) is a metabolite of Bradykinin, cleaved by Aminopeptidase P.

HY-P4205

Aminopeptidase N Ligand (CD13) NGR peptide	Aminopeptidase	Cancer
Aminopeptidase N Ligand (CD13) NGR peptide is a polypeptide targeting CD13 and can be used as a carrier to mediate intracellular transmission. Aminopeptidase N Ligand (CD13) NGR peptide is often used in cancer research .

HY-115431

Antho-rwamide I	Peptides	Neurological Disease
Antho-rwamide I is a neuropeptide that can be isolated from the sea anemone Anthopleura elegantissima. Antho-rwamide I is resistant to nonspecific aminopeptidases, which increases the stability of the peptide after neuronal release .

HY-137946

L-Leucine 4-methoxy-β-naphthylamide hydrochloride	Peptides	Others
L-Leucine 4-methoxy-β-naphthylamide hydrochloride is an aminopeptidase M and leucine aminopeptidase substrate .

HY-P4549

H-D-Ala-D-Ala-D-Ala-D-Ala-OH	Aminopeptidase	Others
H-D-Ala-D-Ala-D-Ala-D-Ala-OH is a substrate for D-aminopeptidase .

HY-P5607

Bombinin	Peptides	Infection
Bombinin is an antimicrobial peptide derived from frog Bombina variegata. Bombinin has a protective effect on aminopeptidase .

HY-P4584

TRH-βNA	Biochemical Assay Reagents	Others
TRH-βNA is a substrate for determining the membrane TRH-deamidating enzyme (TRH-DE) activity and membrane pyroglutamyl aminopeptidase II (PPII) activity .

HY-P4658

H-Val-Ala-pNA	Peptides	Others
H-Val-Ala-pNA is a substrate for the dipeptide aminopeptidase (DPAPase) of Streptococcus bovis. H-Val-Ala-pNA can be used to measure the activity of the protease .

HY-P4393

H-Leu-Trp-Met-Arg-OH	Aminopeptidase	Others
H-Leu-Trp-Met-Arg-OH is a tetrapeptide. H-Leu-Trp-Met-Arg-OH can be used as a substrate for *aminopeptidase*-mediated hydrolysis studies .

HY-P4553

H-Met-Pro-OH	Amino Acid Derivatives	Others
H-Met-Pro-OH is a dipeptide containing methionine and proline. H-Met-Pro-OH is a substrate for aminopeptidase P (APP) and skin fibroblast prolidase .

HY-P4461

Ala-Ala-Pro-pNA	Peptides	Others
Ala-Ala-Pro-pNA is a tripeptide, including chromophoric amino acids Pro-pNA. Ala-Ala-Pro-pNA is targeted by tripeptidyl aminopeptidase (SM-TAP) .

HY-P4227A

WRVYEKC(dnp)ALK tetraTFA	Peptides	Metabolic Disease
WRVYEKC(dnp)ALK tetraTFA contains tryptophan that can be liberated from the dinitrophenol (DNP) quencher by aminopeptidase activity. WRVYEKC(dnp)ALK tetraTFA can be used as a hydrolysis reaction decapeptide substrate .

HY-111173

Diprotin B	Dipeptidyl Peptidase	Others
Diprotin B is a dipeptidyl aminopeptidase IV (DPP IV) inhibitor. The apparent competitive inhibition of DPP-IV by the diprotins is a kinetic artifact, derived from the substrate-like nature of tripeptides containing a penultimate proline residue .

HY-P4528

Ala-Phe-Pro-βNA	Peptides	Others
Ala-Phe-Pro-βNA is the subsrate of prolyl tripeptidyl aminopeptidase, which is from Porphyromonas gingivalis. Ala-Phe-Pro-βNA binds to H-Ala-Ile-pyrrolidin-2-yl boronic acid for PTP39 and the E636A mutant with K_i values of 88.1 nM and 48.8 nM, respectivley .

HY-P2075

EMD 55068	Renin	Endocrinology
EMD 55068 is a renin antagonist. EMD 55068 inhibits the uptake of taurocholate .

HY-P10472

Azaline B	GnRH Receptor	Endocrinology
Azaline B is an antagonist for gonadotropin-releasing hormone (GnRH) with IC₅₀ of 1.37 nM, Azaline B can be used in research of sex hormone-related pathological states, ovulation induction and male contraception .

HY-P4757

N1-Glutathionyl-spermidine disulfide	Peptides	Others
N1-Glutathionyl-spermidine disulfide is a substrate of trypanothione reductase .

HY-P10341

ZP3022	GCGR	Metabolic Disease
ZP3022 is a dual agonist of glucagon-like peptide-1 (GLP-1) and gastrin that has the ability to sustainably improve glycemic control. Additionally, ZP3022 can effectively increase β-cell mass, promote β-cell proliferation, and enhance the function of pancreatic islets. ZP3022 can be used in anti-diabetic research .

HY-W345510

Opiorphin	Neprilysin	Neurological Disease
Opiorphin, an opioid peptide, is a potent enkephalin-inactivating zinc ectopeptidases in human inhibitor. Opiorphin inhibits two enkephalin-catabolizing ectoenzymes, human neutral ecto-endopeptidase, hNEP (EC 3.4.24.11) with an IC₅₀ value of 11 μM, and human ecto-aminopeptidase, hAP-N (EC 3.4.11.2). Opiorphin displays potent analgesic activity by activating endogenous opioid-dependent transmission .

HY-P4146

Survodutide BI 456906	GLP Receptor GCGR	Metabolic Disease
Survodutide (BI 456906) is a potent, selective glucagon receptor/GLP-1 receptor (GCGR/GLP-1R) dual agonist with EC₅₀s of 0.52 nM and 0.33 nM in CHO-K1 cells, respectively. Survodutide, a 29-amino-acid peptide, is a potent acylated peptide containing a C18 fatty acid. Survodutide has robust anti-obesity efficacy achieved by increasing energy expenditure and decreasing food intake .

HY-P4146A

Survodutide TFA BI 456906 TFA	GLP Receptor GCGR	Metabolic Disease
Survodutide (BI 456906) TFA is a potent, selective glucagon receptor/GLP-1 receptor (GCGR/GLP-1R) dual agonist with EC₅₀s of 0.52 nM and 0.33 nM in CHO-K1 cells, respectively. Survodutide TFA, a 29-amino-acid peptide, is a potent acylated peptide containing a C18 fatty acid. Survodutide TFA has robust anti-obesity efficacy achieved by increasing energy expenditure and decreasing food intake .

HY-103294

R892	Peptides	Others
R892 is a selective and efficient bradyK_inin B1 receptor antagonist with significant antagonistic activity. The pA2 values of R892 in human and rabbit B1 receptors are 8.8 and 8.6 respectively, indicating its strong anti-activity at these receptors. R892 exhibits selectivity with ID50 values of 2.8 nM and >600 nM for B1 and B2 receptors, respectively, and has no endogenous agonist activity. R892 is resistant to aminopeptidase and kininase II (ACE) degradation and exhibits metabolic stability .

HY-P2434

AP102	Somatostatin Receptor	Neurological Disease Metabolic Disease Cancer
AP102 is a dual SSTR2/SSTR5-specific somatostatin analog (SSA). AP102 is a disulfide-bridged octapeptide SSA containing synthetic iodinated amino acids. AP102 binds with subnanomolar affinity to SSTR2 and SSTR5 (IC₅₀: 0.63 and 0.65 nM, respectively). AP102 does not bind to SSTR1 or SSTR3. AP102 can be used for acromegaly and neuroendocrine tumors research .

HY-P5362

NODAGA-LM3	Somatostatin Receptor	Cancer
NODAGA-LM3 can be labeled by ⁶⁸Ga for PET imaging. ⁶⁸Ga-NODAGA-LM3 is a SSTR2 antagonist, and can be used for imaging of SSTR positive paragangliomas .

HY-P5362A

NODAGA-LM3 TFA	Somatostatin Receptor	Cancer
NODAGA-LM3 TFA can be labeled by ⁶⁸Ga for PET imaging. ⁶⁸Ga-NODAGA-LM3 TFA is a SSTR2 antagonist, and can be used for imaging of SSTR positive paragangliomas .

HY-105168

TAK 044	Endothelin Receptor	Cardiovascular Disease
TAK 044 is an antagonist of Endothelin Receptor. TAK 044 strongly inhibits ET-induced deterioration in various animal models. TAK 044 can be used in study ET-related diseases such as acute myocardial infarction,acute renal failure, acute hepatic malfunction, and subarachnoid hemorrhage .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-13731

PPI-2458	Classification of Application Fields Disease Research Fields Cancer	MetAP
PPI-2458 is a potent, orally active, selective and irreversible inhibitor of methionine aminopeptidase-2 (MetAP-2). PPI-2458 can be used for arthritis and lymphoma research .

HY-113952

Actinonin 5 Publications Verification (-)-Actinonin	Infection Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Disease Research Fields	Aminopeptidase Bacterial MMP Apoptosis Antibiotic
Actinonin ((-)-Actinonin) is a naturally occurring antibacterial agent produced by Actinomyces. Actinonin inhibits aminopeptidase M, aminopeptidase N and leucine aminopeptidase. Actinonin is a potent reversible peptide deformylase (PDF) inhibitor with a K_i of 0.28 nM. Actinonin also inhibits MMP-1, MMP-3, MMP-8, MMP-9, and hmeprin α with K_i values of 300 nM, 1,700 nM, 190 nM, 330 nM, and 20 nM, respectively. Actinonin is an apoptosis inducer. Actinonin has antiproliferative and antitumor activities .

HY-B0134A

Bestatin hydrochloride Maximum Cited Publications 7 Publications Verification Ubenimex hydrochloride	Infection Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease Research Fields	Aminopeptidase Bacterial Antibiotic
Bestatin hydrochloride is an inhibitor of *CD13 (Aminopeptidase* N)/APN and leukotriene A4 hydrolase**, used for cancer research.

HY-114336

Enocyanin 1 Publications Verification	Anthocyans Flavonoids Classification of Application Fields Source classification Vitis vinifera cv. Zalema Plants Vitaceae Disease Research Fields Inflammation/Immunology	Phosphatase
Enocyanin is an anthocyanin extracted from grapes. Enocyanin shows inhibitory effect on the leucine aminopeptidase, acid phosphatase, γ-glutamyl transpeptidase and esterase activity .

HY-B0134

Bestatin Maximum Cited Publications 7 Publications Verification Ubenimex	Infection Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease Research Fields	Aminopeptidase Bacterial Antibiotic
Bestatin is a natural, broad-spectrum, and competitive *CD13 (Aminopeptidase* N)/APN and leukotriene A4 hydrolase** inhibitor. Bestatin has anticancer effects .

HY-P2842

*Aminopeptidase*	Classification of Application Fields Disease Research Fields Cancer	Others
Aminopeptidase catalyzes the cleavage of amino acids from the amino terminus of protein or peptide substrates .

HY-108729

Tripeptidyl aminopeptidase Cerliponase alfa	Structural Classification Natural Products Neurological Disease Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Tripeptidyl aminopeptidase (Cerliponase alfa) removes tripeptides from the free NH, terminus of longer peptides. Tripeptidyl aminopeptidase has the potential for the research of CLN2 disease .

HY-125422

Matlystatin A	Structural Classification Natural Products Microorganisms Source classification	Aminopeptidase
Matlystatin A is a potent *aminopeptidase* inhibitor, with IC₅₀ values of 0.3 μM and 0.56 μM against 92 kDa and 72 kDa type IV collagenases, respectively. Matlystatin A can be utilized in cancer research .

HY-B0134B

Bestatin trifluoroacetate Ubenimex trifluoroacetate	Infection Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease Research Fields	Aminopeptidase Bacterial Antibiotic
Bestatin trifluoroacetate is an inhibitor of *CD13 (Aminopeptidase* N)/APN and leukotriene A4 hydrolase**, used for cancer research.

HY-116306

Probestin	Structural Classification Natural Products Microorganisms Source classification	Aminopeptidase
Probestin is a potent aminopeptidase N (APN) inhibitor produced by Streptomyces cyanogens MH663-2F6 .

HY-116126

Leuhistin	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification	Aminopeptidase
Leuhistin is an AP-M (aminopeptidase-M) inhibitor. AP-M is an inactivating enzyme of bioactive peptides in cerebral membranes. Leuhistin can be produced by Bacillus laterosporus BMI156-14F1 .

HY-B0134R

Bestatin (Standard)	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification	Aminopeptidase Bacterial Antibiotic
Bestatin (Standard) is the analytical standard of Bestatin. This product is intended for research and analytical applications. Bestatin is a natural, broad-spectrum, and competitive *CD13 (Aminopeptidase* N)/APN and leukotriene A4 hydrolase** inhibitor. Bestatin has anticancer effects .

HY-125564

Acetyltrialanine	Structural Classification Natural Products Microorganisms Source classification	Aminopeptidase
Acetyltrialanine is a peptide containing three amino acid residues in which the N-terminal amino acid is acetylated and used as a substrate for Nα-acetyl alanine aminopeptidase in order to study the activity and properties of the enzyme. Acetyltrialanine can be used in the study of protein degradation and N-terminal regulation .

HY-126564

Ebelactone A	Structural Classification Natural Products Microorganisms Source classification	Lipase MetAP
Ebelactone A is a mycolic acid β-lactone, which exhibits inhibitory activity for esterase, lipase, fMet aminopeptidase (fMet AP) and PNBase, with IC₅₀s of 56, 3, 8 and 7.5 μM, respectively . Ebelactone A inhibits cutinase, exhibits plants protective potency against Erysiphe graminis .

HY-121071

Ascamycin	Infection Structural Classification Microorganisms Classification of Application Fields Antibiotics Source classification Antibacterial Disease Research Disease Research Fields Other Antibiotics	Bacterial Nucleoside Antimetabolite/Analog Antibiotic
Ascamycin is a 5'-O-sulfonamide ribonucleoside antibiotic produced by Streptomyces sp. JCM9888. Ascamycin has a selective antibacterial activity against *Xanthomonas* species with MIC values of 0.4 μg/mL, 12.5 μg/mL and 12.5 μg/mL for *Xanthomonas citri, Xanthomonas oryzae* and *Mycobacterium phlei*, respectively .

HY-N9898

Sinocrassoside C1	Structural Classification Sinocrassula indica (Decne.) Berger Flavonoids Flavones Source classification Crassulaceae Plants Saccharides Monosaccharides	Others
Sinocrassoside C1 is a natural compound isolated from themethanolic extract of the whole plant ofSinocrassula indica (Crassulaceae) .

Species:	Human (17) Rat (3) Mouse (7)
Tag:	SUMO (1) His (27) Tag Free (3) Strep (2) Myc (1) Flag (1)
Source:	HEK293 (11) Sf9 insect cells (6) E. coli (13)

Cat. No.	Compare	Product Name	Species	Source

HY-P7498

	Aminopeptidase P1 Protein, Human (His) rHuaminopeptidase P1, His; XPNPEP1; aminopeptidase P1	Human	E. coli
	Aminopeptidase P1 Protein, Human (His) is a recombinant human Aminopeptidase P1 with a His tag at the C-terminus. Aminopeptidase P1 belongs to a family of aminopeptidase Ps (aminopeptidases P1-3 encoded by the Xpnpep1-3 genes) that cleave the N-terminal amino acid residue of peptides in which the penultimate amino acid is proline.

HY-P72826

	Aminopeptidase A Protein, Rat (sf9, His) Glutamyl aminopeptidase; EAP; AP-A; CD249; ENPEP	Rat	Sf9 insect cells
	Aminopeptidase A, modulated by calcium, regulates central hypertension by preferentially cleaving N-terminal acidic residues from peptides, including angiotensin II. Aminopeptidase A Protein, Rat (sf9, His) is the recombinant rat-derived Aminopeptidase A protein, expressed by Sf9 insect cells , with N-His labeled tag. The total length of Aminopeptidase A Protein, Rat (sf9, His) is 905 a.a., with molecular weight of ~116 kDa.

HY-P72824

	Aminopeptidase A Protein, Human (sf9, His) Glutamyl aminopeptidase; EAP; AP-A; CD249; ENPEP	Human	Sf9 insect cells
	Aminopeptidase A protein has calcium-regulating activity and plays a key role in central hypertension by preferentially cleaving N-terminal acidic residues, including angiotensin II. The specificity of this enzyme highlights its involvement in the regulation of blood pressure-related peptides, suggesting potential implications for the physiological mechanisms of hypertension. Aminopeptidase A Protein, Human (sf9, His) is the recombinant human-derived Aminopeptidase A protein, expressed by Sf9 insect cells , with N-His labeled tag.

HY-P72825

	Aminopeptidase A Protein, Mouse (sf9, His) Glutamyl aminopeptidase; EAP; AP-A; CD249; ENPEP	Mouse	Sf9 insect cells
	The aminopeptidase A protein is a key player in the regulation of central hypertension, exerting its effects by selectively cleaving the N-terminal acidic residues of peptides such as angiotensin II. The enzyme's preference for specific substrates is regulated by calcium levels, underscoring its critical role in controlling blood pressure and maintaining cardiovascular health. Aminopeptidase A Protein, Mouse (sf9, His) is the recombinant mouse-derived Aminopeptidase A protein, expressed by Sf9 insect cells , with N-His labeled tag. The total length of Aminopeptidase A Protein, Mouse (sf9, His) is 905 a.a., with molecular weight of ~113 kDa.

HY-P70051

	Aminopeptidase N/APN Protein, Mouse (HEK293, His) rMuaminopeptidase N/APN, His; aminopeptidase N; ANPEP; AP-M; APN; AP-N; CD13 antigen; CD13; CD13APN; PEPN; PEPNhAPN	Mouse	HEK293
	Aminopeptidase N/APN proteins act as aminopeptidases with broad specificity, assisting in the final stages of peptide digestion and processing of various peptides, including the hormones angiotensin III/IV and neuropeptides.Aminopeptidase N/APN Protein, Mouse (HEK293, His) is the recombinant mouse-derived Aminopeptidase N/APN protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P7899A

	Aminopeptidase N/APN Protein, Human (HEK293, His) rHuaminopeptidase N/APN Protein, His; aminopeptidase N; ANPEP; AP-M; APN; AP-N; CD13 antigen; CD13; CD13APN; PEPN; PEPNhAPN	Human	HEK293
	Aminopeptidase N/APN protein is a disulfide-bonded homotrimer functioning as a broad specificity aminopeptidase. It plays a crucial role in peptide digestion, peptide processing, antigen presentation, angiogenesis, and cholesterol crystallization. APN protein also interacts with the amino acid transporter SLC6A19 and acts as a receptor for human coronavirus 229E/HCoV-229E during infection. Aminopeptidase N/APN Protein, Human (HEK293, His) is the recombinant human-derived Aminopeptidase N/APN protein, expressed by HEK293 , with C-His labeled tag. The total length of Aminopeptidase N/APN Protein, Human (HEK293, His) is 899 a.a., with molecular weight of 130-140 kDa.

HY-P7899

	Aminopeptidase N/APN Protein, Human (HEK293, His, solution) rHuaminopeptidase N/APN Protein, His; aminopeptidase N; ANPEP; AP-M; APN; AP-N; CD13 antigen; CD13; CD13APN; PEPN; PEPNhAPN	Human	HEK293
	Aminopeptidase N/APN Protein, Human (HEK 293, His) is a recombinant aminopeptidase N/APN protein with a His tag. APN (also known as CD13) is a Zn²⁺ dependent membrane-bound ectopeptidase that degrades preferentially proteins and peptides with a N-terminal neutral amino acid.

HY-P700260

	Aminopeptidase P1 Protein, Human (His-SUMO) Aminoacylproline aminopeptidase; aminopeptidase P, cytosolic; APP1; Cytosolic aminopeptidase P; RP11 451M19.1; sAmp; Soluble aminopeptidase P; soluble; X Pro aminopeptidase 1; X prolyl aminopeptidase (aminopeptidase P) 1; X prolyl aminopeptidase (aminopeptidase P) 1 soluble; X prolyl aminopeptidase 1; X prolyl aminopeptidase 1 soluble; X-Pro aminopeptidase 1; X-prolyl aminopeptidase 1; Xaa Pro aminopeptidase 1; Xaa-Pro aminopeptidase 1; XPNPEP 1; XPNPEP; xpnpep1; XPNPEPL; XPNPEPL1; XPP1_HUMAN	Human	E. coli
	Aminopeptidase P1 Protein, a metalloaminopeptidase, crucially catalyzes the removal of penultimate prolyl residues from peptide N-termini, including substrates like Arg-Pro-Pro. This activity significantly contributes to specific peptide degradation, exemplified in bradykinin processing. Aminopeptidase P1's selective prolyl cleavage underscores its importance in modulating peptide structures and functions within biological systems. Aminopeptidase P1 Protein, Human (His-SUMO) is the recombinant human-derived Aminopeptidase P1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag. The total length of Aminopeptidase P1 Protein, Human (His-SUMO) is 622 a.a., with molecular weight of ~85.8 kDa.

HY-P7499

	Aminopeptidase P2 Protein, Human (HEK293, His) rHuaminopeptidase P2, His; XPNPEP2; aminopeptidase P2	Human	HEK293
	Aminopeptidase P2 Protein, Human (HEK293, His), a recombinant human Aminopeptidase P2 produced in HEK293 cells, has a His tag at the C-terminus. Aminopeptidase P2 is an aminoacylproline hydrolase that specifically removes the N-terminal amino acid from peptides with a penultimate prolyl residue.

HY-P702168

	*leucyl aminopeptidase* Protein, Geobacillus kaustophilus** pepA; Probable cytosol aminopeptidase; Leucine aminopeptidase; LAP; Leucyl aminopeptidase	Others	E. coli
	Leucyl aminopeptidase proteins play a role in the putative processing and normal turnover of proteins within cells. It catalyzes the removal of unsubstituted N-terminal amino acids from peptides, suggesting involvement in complex mechanisms controlling intracellular protein dynamics. leucyl aminopeptidase Protein, Geobacillus kaustophilus is the recombinant leucyl aminopeptidase protein, expressed by E. coli , with tag free. The total length of leucyl aminopeptidase Protein, Geobacillus kaustophilus is 500 a.a., .

HY-P702169

	*leucyl aminopeptidase* Protein, Geobacillus kaustophilus (His)** pepA; Probable cytosol aminopeptidase; Leucine aminopeptidase; LAP; Leucyl aminopeptidase	Others	E. coli
	Leucyl aminopeptidase proteins play a role in the putative processing and normal turnover of proteins within cells. It catalyzes the removal of unsubstituted N-terminal amino acids from peptides, suggesting involvement in complex mechanisms controlling intracellular protein dynamics. leucyl aminopeptidase Protein, Geobacillus kaustophilus (His) is the recombinant leucyl aminopeptidase protein, expressed by E. coli , with N-6*His labeled tag. The total length of leucyl aminopeptidase Protein, Geobacillus kaustophilus (His) is 500 a.a., .

HY-P71435

	XPNPEP3 Protein, Human (His) Probable Xaa-Pro aminopeptidase 3; X-Pro aminopeptidase 3; aminopeptidase P3; APP3; XPNPEP3	Human	E. coli
	The XPNPEP3 protein catalyzes the removal of prolyl residues from N-terminal peptides (such as Leu-Pro-Ala) and has low activity towards Ala or Ser at the P1 site. XPNPEP3 Protein, Human (His) is the recombinant human-derived XPNPEP3 protein, expressed by E. coli , with N-6His, C-6His labeled tag. The total length of XPNPEP3 Protein, Human (His) is 507 a.a., with molecular weight of ~65.0 kDa.

HY-P703772

	XPNPEP2 Protein, Mouse (HEK293, His) Xaa-Pro aminopeptidase 2; Membrane-bound aminopeptidase P; Membrane-bound APP; mAPP; X-prolyl aminopeptidase 2; Xpnpep2;	Mouse	HEK293

HY-P703785

	XPNPEP2 Protein, Rat (HEK293, His) Xaa-Pro aminopeptidase 2; Membrane-bound aminopeptidase P; Membrane-bound APP; mAPP; X-prolyl aminopeptidase 2; Xpnpep2	Rat	HEK293

HY-P70380

	*METAP1/Methionine aminopeptidase* 1 Protein, Human** rHuMethionine aminopeptidase 1/METAP1; Methionine aminopeptidase 1; MAP 1; MetAP 1; Peptidase M 1; METAP1	Human	E. coli
	METAP1 (or methionine aminopeptidase 1) plays a crucial role in protein synthesis by co-translationally removing N-terminal methionine from nascent proteins.This enzymatic activity is particularly relevant when the second residue in the primary sequence is small and uncharged (including residues such as Ala, Cys, Gly, Pro, Ser, Thr or Val).METAP1/Methionine aminopeptidase 1 Protein, Human is the recombinant human-derived METAP1/Methionine aminopeptidase 1 protein, expressed by E.coli , with tag free.

HY-P75925

	*METAP2/Methionine aminopeptidase* 2 Protein, Mouse (sf9, His)** Methionine aminopeptidase 2; MAP 2; p67eIF2; Peptidase M; Mnpep	Mouse	Sf9 insect cells
	METAP2, also known as methionine aminopeptidase 2, plays a critical role in protein synthesis by co-translationally removing N-terminal methionine from nascent proteins. This enzymatic activity is particularly pronounced when the second residue in the primary sequence is small and uncharged (including residues such as Ala, Cys, Gly, Pro, Ser, Thr, or Val). METAP2/Methionine aminopeptidase 2 Protein, Mouse (sf9, His) is the recombinant mouse-derived METAP2/Methionine aminopeptidase 2 protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of METAP2/Methionine aminopeptidase 2 Protein, Mouse (sf9, His) is 477 a.a., with molecular weight of ~60 kDa.

HY-P70364

	*METAP2/Methionine aminopeptidase* 2 Protein, Human (Sf9, His)** rHuMethionine aminopeptidase 2/METAP2, His; Methionine aminopeptidase 2; MAP 2; MetAP 2; p67; p67eIF2; Peptidase M; METAP2; MAP2	Human	Sf9 insect cells
	METAP2/Methionine aminopeptidase 2 protein removes N-terminal methionine from nascent proteins. It preferentially cleaves when the second residue is small and uncharged. METAP2 has higher catalytic activity for Met-Val peptides than METAP1, suggesting its role in processing Met-Val and Met-Thr sequences in vivo. It also protects EIF2S1 from phosphorylation by inhibitory kinases, regulating protein synthesis. METAP2/Methionine aminopeptidase 2 Protein, Human (Sf9, His) is the recombinant human-derived METAP2/Methionine aminopeptidase 2 protein, expressed by Sf9 insect cells , with N-6*His labeled tag.

HY-P70862

	*METAP1D/Methionine aminopeptidase* 1D Protein, Human (His)** Methionine aminopeptidase 1D Mitochondrial; Methionyl aminopeptidase Type 1D Mitochondrial; METAP1D; MAP1D	Human	E. coli
	METAP1D or methionine aminopeptidase 1D plays a crucial role in protein maturation, catalyzing the removal of N-terminal methionine from nascent proteins. Its activity is prominent in the smaller, uncharged second residue (Met-Ala, Cys, Gly, Pro, Ser, Thr or Val). METAP1D/Methionine aminopeptidase 1D Protein, Human (His) is the recombinant human-derived METAP1D/Methionine aminopeptidase 1D protein, expressed by E. coli , with N-6His, C-6His labeled tag. The total length of METAP1D/Methionine aminopeptidase 1D Protein, Human (His) is 292 a.a., with molecular weight of 35-40 kDa.

HY-P703497

	dapb2 Protein, Pseudoxanthomonas mexicana (Flag, His) Dipeptidyl aminopeptidase BII; dapb2; Pseudoxanthomonas mexicana; aminopeptidase; Hydrolase; Protease	Others	E. coli
	dapb2 Protein, Pseudoxanthomonas mexicana (Flag, His) is the recombinant dapb2, expressed by E. coli , with His, Flag labeled tag. The total length of dapb2 Protein, Pseudoxanthomonas mexicana (Flag, His) is 698 a.a., .

HY-P75756

	ERAP2 Protein, Human (HEK293, His) Endoplasmic reticulum aminopeptidase 2; L-RAP; ERAP2; LRAP	Human	HEK293
	ERAP2 protein, a key aminopeptidase, plays a pivotal role in peptide trimming, crucial for generating peptides binding to HLA class I molecules. By selectively hydrolyzing basic residues like Arginine (Arg) and Lysine (Lys), ERAP2 precisely customizes longer precursor peptides, ensuring optimal length for effective presentation on MHC class I molecules. ERAP2 Protein, Human (HEK293, His) is the recombinant human-derived ERAP2 protein, expressed by HEK293 , with N-His, N-10*His labeled tag. The total length of ERAP2 Protein, Human (HEK293, His) is 905 a.a., with molecular weight of 115-125 kDa.

HY-P77098

	NAALADL1 Protein, Mouse (HEK293, His) aminopeptidase NAALADL1; Gm964; Naaladasel	Mouse	HEK293
	The NAALADL1 protein is an aminopeptidase that efficiently hydrolyzes a variety of substrates, except those with specific amino acid positions. It has lower activity against substrates containing Asp or Glu at the P2' position or Pro at the P3' position. NAALADL1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived NAALADL1 protein, expressed by HEK293 , with N-His labeled tag. The total length of NAALADL1 Protein, Mouse (HEK293, His) is 717 a.a., with molecular weight of ~110 kDa.

HY-P77450

	NAALADL1 Protein, Human (HEK293, His) aminopeptidase NAALADL1; I100; Ileal dipeptidylpeptidase; NAALADASEL; NAALADL	Human	HEK293
	NAALADL1 is an aminopeptidase with broad substrate specificity and shows lower activity towards substrates containing Asp or Glu at the P2' position or Pro at the P3' position. It is worth noting that it lacks activity against substrates with Pro at the P3' position and Asp or Glu at the P2' position. NAALADL1 Protein, Human (HEK293, His) is the recombinant human-derived NAALADL1 protein, expressed by HEK293 , with N-His labeled tag. The total length of NAALADL1 Protein, Human (HEK293, His) is 712 a.a., with molecular weight of ~90 kDa.

HY-P74780

	LAP3 Protein, Human (HEK293, His) Cytosol aminopeptidase; LAP-3; Peptidase S; LAP3; LAPEP; PEPS	Human	HEK293
	The LAP3 protein is a cytosolic metallopeptidase that serves as a catalytic entity responsible for the removal of unsubstituted N-terminal hydrophobic amino acids from a variety of peptides. The peptidase activity of LAP3 depends on the presence of Zn(2+) ions, and its substrate specificity can be modulated by binding to other cofactors. LAP3 Protein, Human (HEK293, His) is the recombinant human-derived LAP3 protein, expressed by HEK293 , with C-His labeled tag. The total length of LAP3 Protein, Human (HEK293, His) is 519 a.a., with molecular weight of ~57.6 kDa.

HY-P703362

	DPP3 Protein, Mouse (His, Strep) Dipeptidyl peptidase 3; Dipeptidyl aminopeptidase III; Dipeptidyl arylamidase III; Dipeptidyl peptidase III; DPP III; Enkephalinase B; Dpp3; Mus musculus; Mouse; DPP III; aminopeptidase; Hydrolase; Metalloprotease; Protease; 3.4.14.4	Mouse	E. coli
	DPP3 Protein, Mouse (His, Strep) is the recombinant mouse-derived DPP3, expressed by E. coli , with Strep, His labeled tag. The total length of DPP3 Protein, Mouse (His, Strep) is 738 a.a.,

HY-P703379

	DPP3 Protein, Rat (His, Strep) Dipeptidyl peptidase 3; Dipeptidyl aminopeptidase III; Dipeptidyl arylamidase III; Dipeptidyl peptidase III; DPP III; Enkephalinase B; Dpp3; Rattus norvegicus; Rat; DPP III; aminopeptidase; Hydrolase; Metalloprotease; Protease; 3.4.14.4	Rat	E. coli
	DPP3 Protein, Rat (His, Strep) is the recombinant rat-derived DPP3, expressed by E. coli , with Strep, His labeled tag. The total length of DPP3 Protein, Rat (His, Strep) is 738 a.a.,

HY-P76112

	TPP1 Protein, Mouse (sf9, His) Tripeptidyl-Peptidase 1; LPIC; Tripeptidyl aminopeptidase; TPP-I; CLN2	Mouse	Sf9 insect cells
	TPP1, a lysosomal serine protease, acts as a non-specific lysosomal peptidase, displaying tripeptidyl-peptidase I activity in lysosomal protein degradation. Its function involves generating tripeptides from the breakdown products of other lysosomal proteinases, emphasizing its role in processing and hydrolyzing peptides within the lysosomal environment. Notably, TPP1 requires substrates with an unsubstituted N-terminus. TPP1 Protein, Mouse (sf9, His) is the recombinant mouse-derived TPP1 protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of TPP1 Protein, Mouse (sf9, His) is 562 a.a., with molecular weight of ~60.9 kDa.

HY-P703450

	L-AP4 Protein, Human Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513); aminopeptidase; Hydrolase; Protease	Human	E. coli

HY-P71451

	TPP2 Protein, Human (Myc, His) TPP2; Tripeptidyl-peptidase 2; TPP-2; EC 3.4.14.10; Tripeptidyl aminopeptidase; Tripeptidyl-peptidase II; TPP-II	Human	E. coli
	TPP2 protein, a cytosolic tripeptidyl-peptidase, is a vital component of the ubiquitin-proteasome pathway, operating downstream of the 26S proteasome. It plays a crucial role in maintaining intracellular amino acid homeostasis by releasing N-terminal tripeptides from polypeptides. Furthermore, TPP2 protein is implicated in stimulating adipogenesis, contributing to processes involved in adipose tissue formation. TPP2 Protein, Human (Myc, His) is the recombinant human-derived TPP2 protein, expressed by E. coli , with N-His, C-Myc labeled tag. The total length of TPP2 Protein, Human (Myc, His) is 221 a.a., with molecular weight of ~31.8 kDa.

HY-P70112

	*Dipeptidyl peptidase* 3/DPP3 Protein, Human (His)** rHuDipeptidyl peptidase 3/DPP3, His; Dipeptidyl peptidase 3; Dipeptidyl aminopeptidase III; Dipeptidyl arylamidase III; Dipeptidyl peptidase III; Enkephalinase B; DPP3	Human	E. coli
	According to research reports, dipeptidyl peptidase 3 (DPP3) protein, as an enzymatic entity, is able to cleave and degrade various bioactive peptides, including substrates such as angiotensin, leucine-enkephalin, and methionine-enkephalin. According to the results of multiple studies, in addition to its role in processing these bioactive peptides, DPP3 also has the ability to cleave Arg-Arg-β-naphthylamide in vitro. Dipeptidyl peptidase 3/DPP3 Protein, Human (His) is the recombinant human-derived Dipeptidyl peptidase 3/DPP3 protein, expressed by E. coli , with N-6*His labeled tag. The total length of Dipeptidyl peptidase 3/DPP3 Protein, Human (His) is 737 a.a., with molecular weight of 76-88 kDa.

HY-P70980

	TPP1 Protein, Human (HEK293, His) Tripeptidyl-Peptidase 1; TPP-1; Cell Growth-Inhibiting Gene 1 Protein; Lysosomal Pepstatin-Insensitive Protease; LPIC; Tripeptidyl aminopeptidase; Tripeptidyl-Peptidase I; TPP-I; TPP1; CLN2	Human	HEK293
	TPP1, a lysosomal serine protease, acts as a non-specific lysosomal peptidase, displaying tripeptidyl-peptidase I activity in lysosomal protein degradation. Its function involves generating tripeptides from the breakdown products of other lysosomal proteinases, emphasizing its role in processing and hydrolyzing peptides within the lysosomal environment. Notably, TPP1 requires substrates with an unsubstituted N-terminus. TPP1 Protein, Human (HEK293, His) is the recombinant human-derived TPP1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of TPP1 Protein, Human (HEK293, His) is 544 a.a., with molecular weight of ~78.75 kDa.

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Cat. No.	Product Name	Chemical Structure

HY-B0134AS

Bestatin-d7 hydrochloride
Bestatin-d₇ (hydrochloride) is deuterium labeled Bestatin (hydrochloride). Bestatin hydrochloride is an inhibitor of CD13 (Aminopeptidase N)/APN and leukotriene A4 hydrolase, used for cancer research.

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P80221

	*Methionine Aminopeptidase* 2 Antibody**	WB, ICC/IF, IHC-P, FC	Human, Mouse, Rat
	Methionine Aminopeptidase 2 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 53 kDa, targeting to Methionine Aminopeptidase 2. It can be used for WB,ICC,IF,IHC-P,FC assays with tag free, in the background of Human, Mouse, Rat.

HY-P82414

	ERAP1 Antibody (YA2159) ERAP1; APPILS; ARTS1; KIAA0525; Endoplasmic reticulum aminopeptidase 1; ARTS-1; Adipocyte-derived leucine aminopeptidase; A-LAP; aminopeptidase PILS; Puromycin-insensitive leucyl-specific aminopeptidase; PILS-AP; Type 1 tumor necrosis facto	WB, IHC-P	Human, Rat
	ERAP1 Antibody (YA2159) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2159), targeting ERAP1, with a predicted molecular weight of 107 kDa (observed band size: 107 kDa). ERAP1 Antibody (YA2159) can be used for WB, IHC-P experiment in human, rat background.

HY-P81508

	CD13 Antibody (YA1253) ANPEP; APN; CD13; PEPN; aminopeptidase N; AP-N; hAPN; Alanyl aminopeptidase; aminopeptidase M; AP-M; Microsomal aminopeptidase; Myeloid plasma membrane glycoprotein CD13; gp150; CD antigen CD13	IHC-P	Human
	CD13 Antibody (YA1253) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1253), targeting CD13. CD13 Antibody (YA1253) can be used for IHC-P experiment in human background.

HY-P82419

	AP-A Antibody (YA2164) AP-A; aminopeptidase A; APA; bp1; CD249; EAP; Enpep; Gp160; Ly51	WB, IHC-P	Human
	AP-A Antibody (YA2164) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2164), targeting AP-A, with a predicted molecular weight of 109 kDa (observed band size: 160 kDa). AP-A Antibody (YA2164) can be used for WB, IHC-P experiment in human background.