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and anti-pyretic properties

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37

Inhibitors & Agonists

2

Natural
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7

Isotope-Labeled Compounds

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-106823
    Tebufelone

    NE-11740

    		 COX Lipoxygenase Neurological Disease Inflammation/Immunology
    Tebufelone (NE-11740), a nonsteroidal anti-inflammatory drug (NSAID), is a selective dual COX-2/5-lipoxygenase inhibitor. Tebufelone displays potent anti-inflammatory, analgesic and anti-pyretic properties .
    Tebufelone
  • HY-B0578
    Loxoprofen
    1 Publications Verification

    		 COX Cardiovascular Disease Inflammation/Immunology Cancer
    Loxoprofen is a non-steroidal, orally active anti-inflammatory agent with analgesic and anti-pyretic properties. Loxoprofen is a nonselective COX inhibitor with IC50s of 6.5 and 13.5 μM for COX-1 and COX-2, respectively. Loxoprofen can reduce atherosclerosis and shows antitumor activity .
    Loxoprofen
  • HY-B0578A
    Loxoprofen sodium
    1 Publications Verification

    		 COX Cardiovascular Disease Inflammation/Immunology Cancer
    Loxoprofen sodium is a non-steroidal, orally active anti-inflammatory agent with analgesic and anti-pyretic properties. Loxoprofen sodium is a nonselective COX inhibitor with IC50s of 6.5 and 13.5 μM for COX-1 and COX-2, respectively. Loxoprofen sodium can reduce atherosclerosis and shows antitumor activity .
    Loxoprofen sodium
  • HY-B0440
    Tenoxicam

    Ro-12-0068

    		 COX Inflammation/Immunology
    Tenoxicam (Ro-12-0068), an antiinflammatory agent with analgesic and antipyretic properties.
    Tenoxicam
  • HY-119517
    Seclazone

    		Others Inflammation/Immunology
    Seclazone, a heterocyclic compound, possesses anti-inflammatory, analgesic, antipyretic and diuretic properties. Seclazone is orally active .
    Seclazone
  • HY-B0578S
    Loxoprofen-d4

    		Isotope-Labeled Compounds COX Inflammation/Immunology
    Loxoprofen-d4 is deuterium labeled Loxoprofen. Loxoprofen is a non-steroidal anti-inflammatory agent with analgesic and anti-pyretic properties. Loxoprofen sodium is a nonselective COX inhibitor with IC50s of 6.5 and 13.5 μM for COX-1 and COX-2, respectively[1][2].
    Loxoprofen-d4
  • HY-B0578B
    Loxoprofen sodium (dihydrate)

    		COX Cardiovascular Disease Inflammation/Immunology Cancer
    Loxoprofen sodium dihydrate is a non-steroidal, orally active anti-inflammatory agent with analgesic and anti-pyretic properties. Loxoprofen sodium dihydrate is a nonselective COX inhibitor with IC50s of 6.5 and 13.5 μM for COX-1 and COX-2, respectively. Loxoprofen sodium dihydrate can reduce atherosclerosis and shows antitumor activity .
    Loxoprofen sodium (dihydrate)
  • HY-B0578R
    Loxoprofen (Standard)

    		COX Cardiovascular Disease Inflammation/Immunology Cancer
    Loxoprofen (Standard) is the analytical standard of Loxoprofen. This product is intended for research and analytical applications. Loxoprofen is a non-steroidal, orally active anti-inflammatory agent with analgesic and anti-pyretic properties. Loxoprofen is a nonselective COX inhibitor with IC50s of 6.5 and 13.5 μM for COX-1 and COX-2, respectively. Loxoprofen can reduce atherosclerosis and shows antitumor activity .
    Loxoprofen (Standard)
  • HY-12384
    Tenosal

    		Others Inflammation/Immunology
    Tenosal is a new compound obtained by esterifying salicylic acid with 2-thiophene-carboxylic acid and displays anti-inflammatory, analgesic and antipyretic properties.
    Tenosal
  • HY-B0440S
    Tenoxicam-d3

    Ro-12-0068-d3

    		 Isotope-Labeled Compounds COX Inflammation/Immunology
    Tenoxicam-d3 is the deuterium labeled Tenoxicam. Tenoxicam (Ro-12-0068), an antiinflammatory agent with analgesic and antipyretic properties.
    Tenoxicam-d3
  • HY-W009706
    Alclofenac

    Allopydin; W-7320

    		 Prostaglandin Receptor Inflammation/Immunology
    Alclofenac (Allopydin) is a non-steroidal anti-inflammatory agent (NSAID). Alclofenac is a prostaglandin H2 synthase inhibitor. Alclofenac can be used for rheumatoid arthritis, degenerative joint disease and ankylosing spondylitis research .
    Alclofenac
  • HY-W009706B
    Alclofenac (lysinate)

    Allopydin (lysinate); W-7320 (lysinate)

    		 Prostaglandin Receptor Inflammation/Immunology
    Alclofenac lysinate is a non-steroidal anti-inflammatory agent (NSAID). Alclofenac lysinate is a prostaglandin H2 synthase inhibitor. Alclofenac lysinate can be used for rheumatoid arthritis, degenerative joint disease and ankylosing spondylitis research .
    Alclofenac (lysinate)
  • HY-W009706A
    Alclofenac sodium

    Allopydin sodium; W-7320 sodium

    		 Prostaglandin Receptor Inflammation/Immunology
    Alclofenac sodium is a non-steroidal anti-inflammatory agent (NSAID). Alclofenac sodium is a prostaglandin H2 synthase inhibitor. Alclofenac sodium can be used for rheumatoid arthritis, degenerative joint disease and ankylosing spondylitis research .
    Alclofenac sodium
  • HY-121132
    Butibufen

    		Others Inflammation/Immunology
    Butibufen is an orally active non-steroidal compound. Butibufen shows analgesic and antipyretic properties. Butibufen can be used for the research of inflammation .
    Butibufen
  • HY-17479A
    Amfenac Sodium Hydrate

    		Others Inflammation/Immunology
    Amfenac Sodium Hydrate is an orally active and potent anti-inflammatory compound possessing antipyretic and analgesic properties. Amfenac Sodium Hydrate can be used for the research of acute and chronic inflammation .
    Amfenac Sodium Hydrate
  • HY-105939
    Isofezolac

    LM 22070

    		 PGE synthase Inflammation/Immunology
    Isofezolac (LM 22070) is a non-steroidal anti-inflammatory drug (NSAID) that inhibits prostaglandin-synthetase. Isofezolac anti-inflammatory, and antipyretic properties .
    Isofezolac
  • HY-17482
    Difenpiramide

    Z-876

    		 Others Inflammation/Immunology
    Difenpiramide (Z-876) is a bisphenylalcanoic derivative with marked anti-inflammatory, analgesic, antipyretic and uricosuric properties. Difenpiramide has platelet anti-aggregation activity .
    Difenpiramide
  • HY-B0440R
    Tenoxicam (Standard)

    		COX Inflammation/Immunology
    Tenoxicam (Standard) is the analytical standard of Tenoxicam. This product is intended for research and analytical applications. Tenoxicam (Ro-12-0068), an antiinflammatory agent with analgesic and antipyretic properties.
    Tenoxicam (Standard)
  • HY-17479B
    Amfenac sodium

    AHR 5850 sodium

    		 Others Inflammation/Immunology
    Amfenac sodium (AHR 5850 sodium) is an orally active and potent anti-inflammatory compound possessing antipyretic and analgesic properties. Amfenac sodium can be used for the research of acute and chronic inflammation .
    Amfenac sodium
  • HY-17479
    Amfenac

    		Others Inflammation/Immunology
    Amfenac (AHR 5850) is an orally active and potent anti-inflammatory compound possessing antipyretic and analgesic properties. Amfenac can be used for the research of acute and chronic inflammation .
    Amfenac
  • HY-107795
    Benorilate
    1 Publications Verification

    Salipran

    		 Prostaglandin Receptor Inflammation/Immunology Endocrinology
    Benorylate (Salipran) is the esterification product of paracetamol and acetylsalicylic acid. Benorylate has anti-inflammatory, analgesic and antipyretic properties. Benorylate could also inhibit prostaglandin (PG) synthesis .
    Benorilate
  • HY-17479S
    Amfenac-d5

    		Isotope-Labeled Compounds Others
    Amfenac-d5 is the deuterium labeled Amfenac. Amfenac is an orally active and potent anti-inflammatory compound possessing antipyretic and analgesic properties. Amfenac can be used for the research of acute and chronic inflammation .
    Amfenac-d5
  • HY-17479BS
    Amfenac-d5 sodium

    		Isotope-Labeled Compounds Others
    Amfenac-d5 sodium is deuterated-labeled Amfenac sodium. Amfenac Sodium is an orally active and potent anti-inflammatory compound possessing antipyretic and analgesic properties. Amfenac Sodium can be used for the research of acute and chronic inflammation .
    Amfenac-d5 sodium
  • HY-B0363S
    Nimesulide D5

    		COX Inflammation/Immunology
    Nimesulide-d5 is a deuterium labeled Nimesulide. Nimesulide is a selective COX-2 inhibitor, with IC50s of 70 nM-70 μM in a time-dependent manner, but it shows no effect on COX-1 (IC50 >100 μM). Nimesulide has potent anti-inflammatory, analgesic and antipyretic properties[1][2].
    Nimesulide D5
  • HY-17361
    Etofenamate

    		COX Inflammation/Immunology
    Etofenamate, a non-steroid anti-inflammatory agent (NSAID) and a non-selective COX inhibitor, possesses analgesic, anti-rheumatic, antipyretic and anti-inflammatory properties. Etofenamate is used in the research for osteoarthritis, arthritis and other inflammatory diseases .
    Etofenamate
  • HY-B0363
    Nimesulide
    Maximum Cited Publications
    9 Publications Verification

    R805

    		 COX Inflammation/Immunology Cancer
    Nimesulide is a selective COX-2 inhibitor, with IC50s of 70 nM-70 μM in a time-dependent manner, but it shows no effect on COX-1 (IC50 >100 μM). Nimesulide has potent anti-inflammatory, analgesic and antipyretic properties.
    Nimesulide
  • HY-107795R
    Benorilate (Standard)

    		Prostaglandin Receptor Inflammation/Immunology Endocrinology
    Benorilate (Standard) is the analytical standard of Benorilate. This product is intended for research and analytical applications. Benorylate (Salipran) is the esterification product of paracetamol and acetylsalicylic acid. Benorylate has anti-inflammatory, analgesic and antipyretic properties. Benorylate could also inhibit prostaglandin (PG) synthesis .
    Benorilate (Standard)
  • HY-17361S
    Etofenamate-d4

    		Isotope-Labeled Compounds COX Inflammation/Immunology
    Etofenamate-d4 is the deuterium labeled Etofenamate. Etofenamate, a non-steroid anti-inflammatory agent (NSAID) and a non-selective COX inhibitor, possesses analgesic, anti-rheumatic, antipyretic and anti-inflammatory properties. Etofenamate is used in the research for osteoarthritis, arthritis and other inflammatory diseases[1][2][3].
    Etofenamate-d4
  • HY-135731AS
    4-Methylamino antipyrine-d3 hydrochloride

    		Isotope-Labeled Compounds COX Drug Metabolite Inflammation/Immunology
    4-Methylamino antipyrine-d3 (hydrochloride) is deuterium labeled 4-Methylamino antipyrine (hydrochloride). 4-Methylamino antipyrine hydrochloride is an active metabolite of Metamizole. Metamizole is a pyrazolone non-steroidal anti-inflammatory drug (NSAID) and inhibits COX. Metamizole is an nonopioid analgesic agent and can be used for pain and fever[1][2][3]. 4-Methylamino antipyrine hydrochloride has analgesic, antipyretic, and relatively weak antiinflammatory properties[2].
    4-Methylamino antipyrine-d3 hydrochloride
  • HY-135731
    4-Methylamino antipyrine

    		COX Drug Metabolite Inflammation/Immunology
    4-Methylamino antipyrine is an active metabolite of Metamizole. Metamizole is a pyrazolone non-steroidal anti-inflammatory drug (NSAID) and inhibits COX. Metamizole is an nonopioid analgesic agent and can be used for pain and fever . 4-Methylamino antipyrine has analgesic, antipyretic, and relatively weak antiinflammatory properties .
    4-Methylamino antipyrine
  • HY-135731A
    4-Methylamino antipyrine hydrochloride

    		COX Drug Metabolite Inflammation/Immunology
    4-Methylamino antipyrine hydrochloride is an active metabolite of Metamizole. Metamizole is a pyrazolone non-steroidal anti-inflammatory drug (NSAID) and inhibits COX. Metamizole is an nonopioid analgesic agent and can be used for pain and fever . 4-Methylamino antipyrine hydrochloride has analgesic, antipyretic, and relatively weak antiinflammatory properties .
    4-Methylamino antipyrine hydrochloride
  • HY-17361R
    Etofenamate (Standard)

    		COX Inflammation/Immunology
    Etofenamate (Standard) is the analytical standard of Etofenamate. This product is intended for research and analytical applications. Etofenamate, a non-steroid anti-inflammatory agent (NSAID) and a non-selective COX inhibitor, possesses analgesic, anti-rheumatic, antipyretic and anti-inflammatory properties. Etofenamate is used in the research for osteoarthritis, arthritis and other inflammatory diseases .
    Etofenamate (Standard)
  • HY-N3187
    Nimbin

    		Flavivirus Dengue virus Fungal Bacterial Histamine Receptor Infection Neurological Disease Inflammation/Immunology Cancer
    Nimbin is a intermediate limonoid isolated from Azadirachta. Nimbin prevents tau aggregation and increases cell viability. Nimbin is effective inhibits the envelope protein of dengue virus. Nimbin has anti-inflammatory, antipyretic, antifungal, antihistamine, antiseptic, antioxidant, anti-cancer and anti-viral properties. Nimbin can across blood-brain barrier .
    Nimbin
  • HY-B0363R
    Nimesulide (Standard)

    		COX Inflammation/Immunology Cancer
    Nimesulide (Standard) is the analytical standard of Nimesulide. This product is intended for research and analytical applications. Nimesulide is a selective COX-2 inhibitor, with IC50s of 70 nM-70 μM in a time-dependent manner, but it shows no effect on COX-1 (IC50 >100 μM). Nimesulide has potent anti-inflammatory, analgesic and antipyretic properties.
    Nimesulide (Standard)
  • HY-135731AR
    4-Methylamino antipyrine hydrochloride (Standard)

    		COX Drug Metabolite Inflammation/Immunology
    4-Methylamino antipyrine (hydrochloride) (Standard) is the analytical standard of 4-Methylamino antipyrine (hydrochloride). This product is intended for research and analytical applications. 4-Methylamino antipyrine hydrochloride is an active metabolite of Metamizole. Metamizole is a pyrazolone non-steroidal anti-inflammatory drug (NSAID) and inhibits COX. Metamizole is an nonopioid analgesic agent and can be used for pain and fever . 4-Methylamino antipyrine hydrochloride has analgesic, antipyretic, and relatively weak antiinflammatory properties .
    4-Methylamino antipyrine hydrochloride (Standard)
  • HY-135731R
    4-Methylamino antipyrine (Standard)

    		COX Drug Metabolite Inflammation/Immunology
    4-Methylamino antipyrine (Standard) is the analytical standard of 4-Methylamino antipyrine. This product is intended for research and analytical applications. 4-Methylamino antipyrine is an active metabolite of Metamizole. Metamizole is a pyrazolone non-steroidal anti-inflammatory drug (NSAID) and inhibits COX. Metamizole is an nonopioid analgesic agent and can be used for pain and fever . 4-Methylamino antipyrine has analgesic, antipyretic, and relatively weak antiinflammatory properties .
    4-Methylamino antipyrine (Standard)
  • HY-N3945
    Glaucine

    O,O-Dimethylisoboldine; S-(+)-Glaucine; NSC 34396

    		 Phosphodiesterase (PDE) Calcium Channel MMP NF-κB Inflammation/Immunology Cancer
    Glaucine (O,O-Dimethylisoboldine) is an alkaloid extracted from Glaucium flavum that possesses various activities, including cough relief, bronchodilation, anti-inflammatory effects, analgesia, antipyretic properties, and anticancer effects. Glaucine acts as a selective and orally active inhibitor of phosphodiesterase 4 (PDE4), with a Ki of 3.4 µM in human bronchial tissues and polymorphonuclear leukocytes. Glaucine induces relaxation of human isolated bronchi by antagonizing calcium channels. Additionally, Glaucine inhibits the activation of NF-κB, leading to a reduction in the expression of the MMP-9 gene, thereby suppressing the migration and invasion of breast cancer cells. Therefore, Glaucine holds potential for research in asthma and breast cancer .
    Glaucine

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