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Results for "

bacterium

" in MedChemExpress (MCE) Product Catalog:

63

Inhibitors & Agonists

1

Fluorescent Dye

6

Peptides

28

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-118448
    2,4-Diacetylphloroglucinol

    		Antibiotic Bacterial Fungal Parasite Infection
    2,4-Diacetylphloroglucinol, produced by some isolates of the beneficial bacterium Pseudomonas fluorescens, is a potent antibiotic. 2,4-Diacetylphloroglucinol is active against numerous organisms, including plants, fungi, viruses, bacteria, and nematodes .
    2,4-Diacetylphloroglucinol
  • HY-W012595A
    trans-Benzylideneacetone

    trans-Benzalacetone

    		 Phospholipase Inflammation/Immunology
    trans-Benzylideneacetone (trans-Benzalacetone), a metabolite of gram-negative entomopathogenic bacterium Xenorhabdus nematophila, is an enzyme inhibitor against phospholipase A2 (PLA2). trans-Benzylideneacetone is an immunosuppressant .
    trans-Benzylideneacetone
  • HY-W074648
    Antibacterial agent 18

    		Bacterial Infection
    Antibacterial agent 18 is a multi-arm AIE molecule extracted from patent CN110123801A, compound 23. Antibacterial agent 18 can be used for resisting Gram-positive and Gram-negative bacteria. Antibacterial agent 18 can be conjugated in the cell wall of rigid arm configuration insertion bacterium, and block cell wall turns sugar and turns peptide process, to inhibit or kill bacterium .
    Antibacterial agent 18
  • HY-110354
    UCM05

    G28UCM

    		 Fatty Acid Synthase (FASN) Bacterial Antibiotic Infection Cancer
    UCM05 (G28UCM) is a potent inhibitor of fatty acid synthase (FASN) shows activity against HER2+ breast cancer xenografts and is active in anti-HER2 drug-resistant cell lines. UCM05 is a Filamentous temperature-sensitive protein Z (FtsZ) inhibitor and inhibits the growth of the Gram-positive bacterium B. subtilis with MIC values of 100 μM but lack activity on the Gram-negative bacterium E. coli.
    UCM05
  • HY-Y0403
    3-Chlorobenzoic acid

    m-Chlorobenzoic acid

    		 Endogenous Metabolite Bacterial Infection
    3-Chlorobenzoic acid (m-Chlorobenzoic acid) is the only carbon source for the bacterium .
    3-Chlorobenzoic acid
  • HY-162329
    Antibacterial agent 195

    		Bacterial Fungal Antibiotic Infection Inflammation/Immunology
    Antibacterial agent 195 (compound A20), a Matrine (HY-N0164) derivative, is a potent antibiotic. Antibacterial agent 195 shows antibacterial activity against Gram-positive bacterium (MICS.aureus=0.021 mg/mL; MICP.acnes=0.030 mg/mL), Gram-negative bacterium (MICE.coli=0.092 mg/mL; MICC.albicans=0.379 mg/mL) and Fungus (MIC=2.806 mg/mL) .
    Antibacterial agent 195
  • HY-125617
    α-Lipomycin

    		Antibiotic Bacterial Infection
    α-Lipomycin is an acyclic polyene antibiotic isolated from the gram-positive bacterium Streptomyces aureofaciens Tü117 .
    α-Lipomycin
  • HY-122467
    Kumbicin C

    		Bacterial Infection Cancer
    Kumbicin C is a bis-indolyl benzenoid compound from an Australian soil fungus, Aspergillus kumbius. Kumbicin C inhibits the growth of mouse myeloma cells and the Gram-positive bacterium Bacillus subtilis .
    Kumbicin C
  • HY-N12096
    Galbinic acid

    α-Acetylsalazinic acid

    		 Bacterial Infection
    Galbinic acid (α-Acetylsalazinic acid), a lichen acid, shows antibacterial activities against the Gram-positive bacteria B. cereus, B. subtilis, and S. aureus (MICs=62.5, 62.5, 250 μg/ml, respectively). Galbinic acid inhibits the Gram-negative bacterium E. coli (MIC=125 μg/ml) .
    Galbinic acid
  • HY-132177B
    α1-2,4,6 Fucosidase O, Omnitrophica bacterium

    		Glycosidase Metabolic Disease
    α1-2,4,6 Fucosidase O (EC 3.2.1.51) is a broad specificity exoglycosidase that catalyzes the hydrolysis of terminal α1-2, α1-4 and α1-6 linked fucose residues from oligosaccharides, with α1-6 fucose residues more efficiently .
    α1-2,4,6 Fucosidase O, Omnitrophica bacterium
  • HY-107027
    Polymyxin E2 sulfate

    		Antibiotic Infection
    Polymyxin E2 sulfate is an antibiotic produced by the soil bacterium Bacillus polymyxa .
    Polymyxin E2 sulfate
  • HY-111902
    MCB-3681

    		Bacterial Infection
    MCB-3681 is the antibacterial Oxaquin's active substance, active against gram-positive bacterium .
    MCB-3681
  • HY-W001963
    Pyrrole-2-carboxylic acid

    		Endogenous Metabolite Others
    Pyrrole-2-carboxylic acid is a natural alkaloid from the marine bacterium Pelomonas puraquae sp. Nov.
    Pyrrole-2-carboxylic acid
  • HY-124236
    Chrysobactin

    		Bacterial Others
    Chrysobactin is a compound isolated from the plant pathogenic bacterium Erwinia chrysanthemi. Chrysobactin has siderophore activity .
    Chrysobactin
  • HY-D0705
    Acid Yellow 9 monosodium salt

    Hydrogen 4-aminoazobenzene-3,4'-disulphonate sodium salt

    		 Fluorescent Dye Others
    Acid Yellow 9 monosodium salt is an azo dye, degraded by Pseudomonas fluorescens as sole source of carbon, nitrogen and energy for the bacterium .
    Acid Yellow 9 monosodium salt
  • HY-101128
    Bicyclomycin benzoate
    2 Publications Verification

    FR2054

    		 Bacterial Antibiotic Infection
    Bicyclomycin benzoate is an antibiotic exhibiting activity against a broad spectrum of Gram-negative bacteria and against the Gram-positive bacterium.
    Bicyclomycin benzoate
  • HY-P2120
    Pseudobactin A

    		Bacterial Others
    Pseudobactin A is a non-fluorescent extracellular iron carrier produced by the plant growth-promoting bacterium Pseudomonas B10 .
    Pseudobactin A
  • HY-122334
    Myxopyronin A

    		Antibiotic Infection
    Myxopyronin A is an antibiotic that can be found in culture supernatant of the gliding bacterium Myxococcus fulvus strain Mx f50 (Myxobacterales) .
    Myxopyronin A
  • HY-N12414
    Apicularen A

    		Bacterial Cancer
    Apicularen A is a macrolide isolated from the mucoid bacterium Chondrosporium spp. Apicularen A is also a highly selective inhibitor of vesicular ATPase .
    Apicularen A
  • HY-128780B
    SPR206 acetate
    1 Publications Verification

    		 Bacterial Antibiotic Infection
    SPR206 acetate is a polymyxin analog with antibiotic activity against Gram-negative pathogens, including multidrug-resistant (MDR) variants. SPR206 acetate has an anti-bacterial infection effect by interacting with the bacterium’s outer membrane. The MIC values of SPR206 acetate against Pseudomonas aeruginosa Pa14 and Acinetobacter baumannii NCTC13301 are both 0.125 mg/L .
    SPR206 acetate
  • HY-P5639
    Gageotetrin A

    		Fungal Infection
    Gageotetrin A is an antimicrobial peptide derived from the marine bacterium Bacillus subtilis. Gageotetrin A has antifungal activity, but none toxic to numerous human cancer cells .
    Gageotetrin A
  • HY-137911
    Sparsomycin

    		Bacterial Infection Cancer
    Sparsomycin is a metabolite of the bacterium Streptomyces sparsogenes. Sparsomycin inhibits protein synthesis in both eukaryotic cells and bacteria. Sparsomycin inhibits the translation extension of ribosome PTC .
    Sparsomycin
  • HY-135024
    Phenylacetyl CoA

    Phenylacetyl Coenzyme A

    		 Endogenous Metabolite Metabolic Disease
    Phenylacetyl CoA is an acceptor oxidoreductase. Phenylacetyl CoA is a membrane-bound molybdenum–iron–sulfur enzyme involved in anaerobic metabolism of phenylalanine in the denitrifying bacterium Thauera aromatica .
    Phenylacetyl CoA
  • HY-120066
    Seriniquinone

    		Autophagy Cancer
    Seriniquinone, a selective anti-melanoma agent that targets Dermcidin, induces cell death by autophagocytosis. Seriniquinone is a metabolite produced by a rare marine bacterium of the genus Serinicoccus .
    Seriniquinone
  • HY-N0637AR
    (±)-Eriodictyol (Standard)

    		Melanocortin Receptor Metabolic Disease
    3-Chlorobenzoic acid (Standard) is the analytical standard of 3-Chlorobenzoic acid. This product is intended for research and analytical applications. 3-Chlorobenzoic acid (m-Chlorobenzoic acid) is the only carbon source for the bacterium .
    (±)-Eriodictyol (Standard)
  • HY-Y0403R
    3-Chlorobenzoic acid (Standard)

    		Endogenous Metabolite Bacterial Infection
    3-Chlorobenzoic acid (Standard) is the analytical standard of 3-Chlorobenzoic acid. This product is intended for research and analytical applications. 3-Chlorobenzoic acid (m-Chlorobenzoic acid) is the only carbon source for the bacterium .
    3-Chlorobenzoic acid (Standard)
  • HY-P5646
    Gageotetrin C

    		Bacterial Infection
    Gageotetrin C is an antimicrobial peptide derived from the marine bacterium Bacillus subtilis. Gageotetrin C is more active against fungi (MIC value is 0.02-0.04 μM) .
    Gageotetrin C
  • HY-N6705
    Tropodithietic acid

    		Bacterial Antibiotic Infection
    Tropodithietic acid is a sulfur-containing antibiotic produced by the marine bacterium Phaeobacter inhibens. Tropodithietic acid exhibits a strong antibiotic activity against a broad spectrum of bacteria including alpha- and gammaproteobacteria, flavobacteria and actinobacteria .
    Tropodithietic acid
  • HY-167887
    7PPD-Q

    		Endogenous Metabolite Infection
    7PPD-Q is a substituted p-phenylenediamine antioxidants derivatives. 7PPD-Q has toxic to the bacterium V. fischeri (EC50 = 14.9 mg/L) .
    7PPD-Q
  • HY-135024A
    Phenylacetyl CoA lithium

    Phenylacetyl Coenzyme A lithium

    		 Endogenous Metabolite Metabolic Disease
    Phenylacetyl CoA lithium (Phenylacetyl Coenzyme A lithium) is an acceptor oxidoreductase. Phenylacetyl CoA is a membrane-bound molybdenum–iron–sulfur enzyme involved in anaerobic metabolism of phenylalanine in the denitrifying bacterium Thauera aromatica .
    Phenylacetyl CoA lithium
  • HY-169764
    Pseudane V

    		Endogenous Metabolite Others
    Pseudane V is the secondary metabolite that can be isolated from the marine bacterium Pseudoalteromonas sp. M2. Pseudane V inhibits the melanin synthesis in cell Melan-A, and can be used as a potential skin whitening agent .
    Pseudane V
  • HY-N14193
    Estatin B

    		Cathepsin Inflammation/Immunology
    Estatin B is a thiol protease inhibitor found by the Thermophilic Bacterium M4323, which is specific to thiol proteases such as papain, fig protease, and bromelain. Estatin B inhibits the production of IgE antibodies but not IgG in mice .
    Estatin B
  • HY-142075
    Antibacterial agent 134

    		Bacterial Infection
    Antibacterial agent 134 (compound 1) is an diketopiperazine alkaloid with antimicrobial activity. Antibacterial agent 134 is the major metabolite in the culture of Hymeniacidon perleve associated bioactive bacterium Pseudomonas sp. NJ6-3-1 .
    Antibacterial agent 134
  • HY-W042191
    Oxychlororaphine

    		Fungal Apoptosis Caspase Bcl-2 Family MDM-2/p53 PARP Infection Cancer
    Oxychloroaphine could be isolated from the bacterium Pantoea agglomerans naturally present in soil. Oxychloroaphine has broad-spectrum antifungal activity. Oxychloroaphine has cytotoxicity in a dose-dependent manner and induces apoptosis. Oxychloroaphine can be used in research of cancer .
    Oxychlororaphine
  • HY-111903
    Levomecol

    		Bacterial Infection
    Levomecol (Chloramphenicol), made up of Chloramphenicol, Methyluracil, is a broad-spectrum antibiotic that is derived from the bacterium Streptomyces venezuelae. Levomecol (Chloramphenicol)) stops bacterial growth by binding to the bacterial ribosome (blocking peptidyl transferase) and inhibiting protein synthesis .
    Levomecol
  • HY-121050
    Ambruticin

    W7783

    		 Antibiotic Fungal Infection
    Ambruticin (W7783) is an orally active and potent antifungal antibiotic. Ambruticin represents a class of antibiotics, that can be isolated from a strain of Polyangium cellulosum var. fulvum, a bacterium belonging to the class Myxobacteriales. Ambruticin is a cyclopropyl-polyene-pyran acid and is active against fungi .
    Ambruticin
  • HY-W015786
    4-Ethoxyphenol

    		Bacterial Infection Metabolic Disease
    4-Ethoxyphenol is a natural compound isolated from marine gorgonian-associated bacterium Bacillus amyloliquefaciens SCSIO 00856. 4-Ethoxyphenol shows potent antilarval activity towards Bacillus amphitrite larvae with an EC50 value of 24.1 μg/mL .
    4-Ethoxyphenol
  • HY-118448R
    2,4-Diacetylphloroglucinol (Standard)

    		Antibiotic Bacterial Fungal Parasite Infection
    Tetrachlorvinphos (Standard) is the analytical standard of Tetrachlorvinphos. This product is intended for research and analytical applications. Tetrachlorvinphos is an organophosphorus pesticide that has the activity of inhibiting cholinesterase. Tetrachlorvinphos is used as a pesticide, mainly for the control of pests. Tetrachlorvinphos has low toxicity to mammals .
    2,4-Diacetylphloroglucinol (Standard)
  • HY-117166
    Naftoxate

    K-F-224

    		 Bacterial Infection
    Naftoxate is an ester compound containing aminomethylsulfate, and its ammonium salt analog can inhibit free thiols to chemically weaken the reactive oxygen species (ROS)-sensitive anaerobic bacterium Trichomonas vaginalis and inhibit common pathogens causing vaginal infections: Candida albicans and Staphylococcus aureus .
    Naftoxate
  • HY-112779
    Pertussis Toxin
    Maximum Cited Publications
    10 Publications Verification

    		 Endogenous Metabolite Infection
    Pertussis Toxin is a protein-based AB5-type exotoxin produced by the bacterium Bordetella pertussis, which causes whooping cough. Pertussis Toxin inhibits G protein-coupled receptor (GPR) signaling through Gi proteins .
    Pertussis Toxin
  • HY-N15299
    iso-C15:0 3-OH

    		Endogenous Metabolite Others
    iso-C15:0 3-OH is a fatty acid that can be isolated from strain PLR T. PLR T is a rod shaped, Gram-stain-negative, chemo-organotrophic, heterotrophic, strictly aerobic bacterium isolated from faeces of the mollusc Aplysia punctata .
    iso-C15:0 3-OH
  • HY-W012595AR
    trans-Benzylideneacetone (Standard)

    		Phospholipase Inflammation/Immunology
    trans-Benzylideneacetone (Standard)
  • HY-129252
    Prothracarcin

    		Antibiotic Bacterial Infection Cancer
    Prothracarcin is an antibiotic with antitumor activity that exerts its tumor cell toxicity by covalently binding to the C-2 amino group of guanine residues in the minor groove of DNA. Prothracarcin also shows antibacterial activity against Gram-positive bacteria and some Gram-negative bacteria such as Escherichia coli .
    Prothracarcin
  • HY-156004
    Ziapin 2

    		Bacterial Others
    Ziapin 2 is a molecular optomechanical light transducer. Ziapin 2 is an amphiphilic azobenzene with a strong non-covalent affinity to the plasma membrane. Ziapin 2 can be used to photo-modulate the membrane potential in cells of the Gram-positive bacterium Bacillus subtilis. Ziapin 2 enters the lipid membrane very rapidly (≈ 40 ns) .
    Ziapin 2
  • HY-N9923
    2-C-Methyl-D-erythritol 4-phosphate

    		Bacterial
    2-C-Methyl-D-erythritol 4-phosphate is a metabolite intermediate exclusive to the non-mevalonate MEP pathway, predominantly found in prokaryotes, serving as a precursor for the synthesis of isoprenoids and non-isoprenoids, including vitamins; its absence in humans makes it a promising target for the development of bacterium-specific drugs aimed at treating infectious diseases.
    2-C-Methyl-D-erythritol 4-phosphate
  • HY-163486
    Antituberculosis agent-10

    		Bacterial Infection
    Antituberculosis agent-10 (Compound 9) has excellent antibacterial activity against Mycobacterium tuberculosis (MIC = 0.3 μM). Antituberculosis agent-10 inhibits protein synthesis by targeting the 50S ribosomal subunit of the bacterium, thus exerting its antibacterial effect. Antituberculosis agent-10 is orally active .
    Antituberculosis agent-10
  • HY-E70518
    Oxalate decarboxylase, Microorganism

    		Bacterial Infection
    Oxalate decarboxylase, Microorganism (EC 4.1.1.2), a stress-response enzyme in certain soil bacteria, is a Mn-dependent enzyme in the cupin superfamily and is found in fungi and soil bacteria. Oxalate decarboxylase catalyzes the decarboxylation of the oxalate mono-anion in the soil bacterium Bacillus subtilis. Enzymatic activity of OxDC is strongly pH dependent, with a maximum at around pH 4.0 .
    Oxalate decarboxylase, Microorganism
  • HY-121716
    Pelagiomicin A

    Antibiotic 2088A; LL-14I352α

    		 Bacterial Cancer
    Pelagiomicin A is a novel phenazine antibiotic produced by the marine bacterium Pelagiobacter variabilis. The compound is unstable in water and small alcohols. The absolute structure of its major component, Pelagiomicin A, as well as the properties of minor amounts of other structures, were determined by spectroscopic data and synthesis. Pelagiomicin A is active against both Gram-positive and Gram-negative bacteria and exhibits antitumor activity in vitro and in vivo.
    Pelagiomicin A
  • HY-125117
    Simocyclinone D8

    		DNA/RNA Synthesis Bacterial Infection Cancer
    Simocyclinone D8 is an anthracycline antibiotic with antibacterial and antitumor activity against Gram-positive bacteria. Simocyclinone D8 inhibits DNA gyrase and thus has an inhibitory effect on a variety of tumor cell lines .
    Simocyclinone D8
  • HY-159080
    HgCht2-IN-1

    		Parasite Infection
    HgCht2-IN-1 (compound 1516b) is a HgCht2 inhibitor that successfully inhibits the antagonism of cyst nematodes against nitrogen-fixing rhizobia and phosphate-absorbing arbuscular mycorrhizal symbionts. HgCht2-IN-1 can be used in the study of cyst nematode antagonism against microbial symbionts .
    HgCht2-IN-1

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