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Results for "

cytochalasin

" in MedChemExpress (MCE) Product Catalog:

15

Inhibitors & Agonists

14

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N6774
    Cytochalasin C
    1 Publications Verification

    		 Others Infection
    Cytochalasin C is a cell-permeable fungal toxin and induces the formation of nuclear rodlets. Cytochalasin C is 10 times less toxic in mice than is cytochalasin D .
    Cytochalasin C
  • HY-N6773
    Cytochalasin A

    		HIV Protease Fungal Infection
    Cytochalasin A is a cell-permeable fungal toxin that is an oxidized derivative of cytochalasin B. Cytochalasin A is an inhibitor of HIV-1 protease (IC50=3 μM) and inhibits actin polymerization and interferes with microtubule assembly by reacting with sulfhydryl groups. Antibiotic and fungicidal activitives .
    Cytochalasin A
  • HY-N6772
    Cytochalasin E

    		Autophagy Cancer
    Cytochalasin E, an epoxide containing Aspergillus-derived fungal metabolite, inhibits angiogenesis and tumor growth. Cytochalasin E is a potent actin depolymerization agent, and it binds and caps the barbed end of actin filaments to prevent actin elongation .
    Cytochalasin E
  • HY-16928
    Cytochalasin B
    25+ Cited Publications

    Phomin

    		 Arp2/3 Complex Cancer
    Cytochalasin B is a cell-permeable mycotoxin binding to the barbed end of actin filaments, disrupting the formation of actin polymers, with Kd value of 1.4-2.2 nM for F-actin. Cytochalasin B blocks cell migration.
    Cytochalasin B
  • HY-N10290
    Cytochalasin K

    		Others Others
    Cytochalasin K (Compounds 7) is a cytochalasin that inhibits wheat root elongation with an IC50 of 22.58 μM .
    Cytochalasin K
  • HY-N12195
    Cytochalasin R

    		Fungal Infection
    Cytochalasin R (compound 17) is a cytochalasin analogue that can be isolated from the endophytic fungus Phomopsis sp. xz-18. Cytochalasin R shows potential antifungal activity .
    Cytochalasin R
  • HY-N12193
    Cytochalasin N

    		Others Others
    Cytochalasin N is a cytorelaxin derived from endophytic fungus Phomopsis sp.CIB-109 .
    Cytochalasin N
  • HY-129325
    Cytochalasin H

    		Antibiotic Bacterial Apoptosis Bcl-2 Family Caspase Infection Cancer
    Cytochalasin H is a nature product that could be isolated from fungus Phomopsis sp. Cytochalasin H inhibits cell growth and induces apoptosis. Cytochalasin H has anti-angiogenic activity. Cytochalasin H is an antibiotic and has antibacterial activity .
    Cytochalasin H
  • HY-126556
    Cytochalasin J

    		Microtubule/Tubulin Cancer
    Cytochalasin J is a cytochalasin detivative. Cytochalasin J affects mitotic spindel microtubule organization and kinetochore structure, and exhibits cytotoxicity in human leukemia K562 cell with IC50 of 1.5 μM .
    Cytochalasin J
  • HY-N12194
    Cytochalasin O

    		Others Infection
    Cytochalasin O (compound 13) is a secondary metabolite of the phytopathogenic fungus P. sp. CIB-109 .
    Cytochalasin O
  • HY-N6682
    Cytochalasin D
    Maximum Cited Publications
    48 Publications Verification

    Zygosporin A; NSC 209835

    		 Arp2/3 Complex Antibiotic YAP Infection
    Cytochalasin D (Zygosporin A) is a potent actin polymerization inhibitor, could be derived from fungus. Cytochalasin D has cell-permeable activity. Cytochalasin D inhibits the G-actin–cofilin interaction by binding to G-actin. Cytochalasin D also inhibits the binding of cofilin to F-actin and decreases the rate of both actin polymerization and depolymerization in living cells. Cytochalasin D can reduce exosome release, in turn reducing the amount of survivin present in the tumour environment. Cytochalasin D induces phosphorylation and cytoplasmic retention of Yap .
    Cytochalasin D
  • HY-N10291
    10-Phenyl-[12]-cytochalasins Z16

    		Others Others
    10-Phenyl-[12]-cytochalasins Z16 (Compounds 5) is a cytochalasin that inhibits wheat root elongation with an IC50 of 17.35 μM .
    10-Phenyl-[12]-cytochalasins Z16
  • HY-N8349
    19,20-Epoxycytochalasin D

    		Parasite Endogenous Metabolite Infection Cancer
    19,20-Epoxycytochalasin D, a cytochalasin, is a fungal metabolite from Nemania sp. 19,20-Epoxycytochalasin D shows potent in vitro antiplasmodial activity and phytotoxicity .
    19,20-Epoxycytochalasin D
  • HY-N8385
    19,20-Epoxycytochalasin C

    		Parasite Endogenous Metabolite Infection Cancer
    19,20-Epoxycytochalasin C, a cytochalasin, is a fungal metabolite from Nemania sp. 19,20-Epoxycytochalasin C shows potent in vitro antiplasmodial activity and phytotoxicity .
    19,20-Epoxycytochalasin C
  • HY-N6701
    Dihydrocytochalasin B

    		Arp2/3 Complex Cancer
    Dihydrocytochalasin B (H2CB) is a Cytokinesis inhibitor and changes the morphology of the cells, similar to that of cytochalasin B; does not inhibit glucose transport . Dihydrocytochalasin B (H2CB) disrupts the actin structure and inhibits the ability of growth factors to stimulate DNA synthesis, reversibly blocks initiation of DNA synthesis . Dihydrocytochalasin B (H2CB) inhibits active calcium transport and causes a Ca 2+increase in the mucosal scrapings .
    Dihydrocytochalasin B

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